Clinical trials: Dietary Supplementation
Sarcopenia, Frailty
Sarcopenia Prevention With a Targeted Exercise and Protein Supplementation Program
Physical inactivity and protein malnutrition have been implicated to be key and modifiable causes of enhanced muscle mass loss among seniors.
- Conditions
- Sarcopenia, Frailty, Malnutrition; Protein, Fall
- Trial name
- STRONG (NCT03417531)
- Testing
- Protein Supplement, Protein-free Supplement, Active Exercise
- Where
- 2 sites in Switzerland
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Vitamin A Deficiency
Efficacy of Newborn Vitamin A Supplementation in Improving Immune Function
Vitamin A supplementation at birth may increase survival of infants through one year of age by reducing mortality from infectious diseases, though current studies are not conclusive on this point.
- Trial name
- NCT01583972
- Testing
- retinyl palmitate
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Stroke
Nutrition Blood Outcomes Following Tocotrienol N2B
A natural form of vitamin E called tocotrienol (TCT) has blood thinning and cholesterol lowering properties, both of which may benefit stroke survivors.
- Trial name
- NIIB (NCT01858311)
- Testing
- Tocotrienol Capsules
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Frail Elderly Syndrome
No Association Between Vitamin C and E Supplementation, Frailty, and Grip Strength Over Five Years: The CoLaus Study
To assess the cross-sectional and 5-year prospective association between self-reported vitamin C+E dietary supplementation and markers of grip strength and frailty in community-dwelling Swiss adults.
- Trial name
- CoLaus (NCT03258970)
- Testing
- Observational cohort study
- Where
- Switzerland
- Volunteers
- 2,711 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Diabetes Mellitus, Type 1
Probiotics Supplementation Effect on Glucose Homeostasis in Children With Type 1 Diabetes
Background: Probiotics influence immune homeostasis, through altering gut microbiota. The efficacy of probiotics in diabetes has been shown in preclinical settings as well as in human trials.
- Trial name
- NCT04579341
- Testing
- probiotics
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Chronic Kidney Diseases, Constipation
Polydextrose for Patients With Chronic Kidney Disease
Constipation is a common complication in patients with chronic kidney disease (CKD), especially in hemodialysis (HD) patients. Reduced intake of fibre-rich food is among the most important causes of constipation.
- Trial name
- NCT05336305
- Testing
- Polydextrose
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal Fluminense
Stroke, Ischemic
Effect of Supplementation With Creatine on the Recovery of Ischemic Stroke
Stroke is a leading cause of disability and the second leading cause of death worldwide. Most strokes are ischemic, caused by acute arterial occlusion.
- Trial name
- SUCRE (NCT06576466)
- Testing
- Creatine monohydrate
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Recurrent Respiratory Tract Infections
Impact of Vitamin D Supplementation on Recurrent Respiratory Infections in Paediatric Primary Care.
Up to date, some clinical trial have evaluated the efficacy and safety of Vitamin D supplementation in children with RRI, with no conclusive information.
- Trial name
- NCT02617771
- Testing
- Vitamin D3
- Volunteers
- 84 people
- Sponsor
- Policlinico Hospital
Muscle Loss
The Effect of Creatine on Muscle Loss
The primary aim of this study is to determine the effect of creatine supplementation on muscle mass loss during short-term immobilisation in healthy, young people.
- Trial name
- CML (NCT01894737)
- Testing
- Creatine supplementation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Ulcerative Colitis
Multi-Strain Probiotics Supplementation With Standard Care in Mild to Moderate Ulcerative Colitis
Probiotics are one of the adjunctive treatments that have been extensively explored for Ulcerative colitis (UC) disease management.
- Trial name
- NCT06595719
- Testing
- Multi-Strain Probiotics
- Where
- Malaysia
- Volunteers
- 124 people
- Sponsor
- National University of Malaysia
Body Weight Changes, Athletic Performance
Whey Protein Supplementation in High School Athletes
The overall aim of this project is to compare protein supplementation on performance, recovery, and body composition changes in adolescent soccer players between the whey protein and the control group in response to the…
- Conditions
- Body Weight Changes, Athletic Performance, Recovery, Sleep
- Trial name
- NCT05589129
- Testing
- Whey Protein Supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cirrhosis, Chronic Liver Disease
Copper Supplementation in Cirrhosis
End stage liver disease or cirrhosis is a major cause of mortality in the United States and the world. Other than targeting the underlying cause, such as alcohol cessation and antiviral therapy, very few medical treatments can…
- Conditions
- Cirrhosis, Chronic Liver Disease, Fibrosis, Infection
- Trial name
- NCT07471542
- Testing
- Copper Gluconate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Diet, Healthy, Systemic Inflammatory Response
Effect Dietary Fibre Supplementation on Gut Microbiota Composition
The study involves taking pectin fibre at increasing doses ranging from 5g, 10g and 15g for a total period of 6 weeks with the increase every 2 weeks.
- Trial name
- NCT06758570
- Testing
- Pectin dosages
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Elizabeth Simpson
Healthy
Oral Liposomal Glutathione Supplementation in Healthy Subjects
This trial is designed to provide evidence of the efficacy of liposomal glutathione supplementation on healthy adults. The investigators anticipate that liposomal glutathione supplementation will enhance the levels of blood…
- Trial name
- NCT02278822
- Testing
- Low dose oral liposomal glutathione supplementation, High dose oral liposomal glutathione supplementation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Spinal Cord Injury
The Effect of Probiotic and Prebiotic Supplementation on Gastrointestinal Health in Individuals With Chronic Spinal Cord Injury
The goal of this clinical trial is to evaluate the effect of probiotic and prebiotic supplementation in individuals with chronic spinal cord injury experiencing gastrointestinal complaints.
- Trial name
- PRO-GIDSCI (NCT06870331)
- Testing
- Probiotic, Prebiotic
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Healthy Adult Females, Gastrointestinal Symptoms
The Effect of Daily Supplementation With Humiome® Post LB on Gastrointestinal Symptoms in Female Athletes
Female athletes are often overlooked in scientific research, including the understanding of their digestive system and its impact on overall health, training, and performance.
- Trial name
- GI-Jane (NCT07366931)
- Testing
- Postbiotic
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Metabolic Syndrome, Osteoporosis
Exercise and Flax-Based Nutritional Supplementation for Lowering Cholesterol
The purpose of our study is to use a flaxseed-based nutritional supplement in combination with exercise training (walking) for improving cholesterol levels.
- Trial name
- NCT00204412
- Testing
- Flax lignan, Exercise (walking)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
SIAD - Syndrome of Inappropriate Antidiuresis
Urea for Treatment of Hyponatremia in Patients With SIAD Unresponsive to Fluid Restriction
Hyponatremia due to SIAD is frequently insufficiently corrected by fluid restriction alone, which remains the first-line therapy but is often poorly tolerated. Urea supplementation is recommended as second-line therapy.
- Trial name
- UREA-BIVA (NCT07528365)
- Testing
- urea
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Turin, Italy
Gingivitis and Periodontal Diseases
Alpha-Lipoic Acid as an Adjunct to Non-Surgical Periodontal Treatment in Gingivitis
Gingivitis is an early and reversible form of periodontal disease characterized by an increased inflammatory response to dental biofilm.
- Trial name
- NCT07882394
- Testing
- Alpha-Lipoic Acid 200 mg, Alpha-Lipoic Acid 600 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Biruni University
Iron Deficiency Anemia Treatment, Iron Deficiency Anemia
Probiotic Use in Oral Iron Replacement Deficiency Anemia Patients Initiating Oral Iron Replacement
Investigation of gastrointestinal tolerability, treatment compliance and iron status markers in patients with iron deficiency anemia who received oral iron replacement therapy with versus without concomitant probiotic…
- Trial name
- NCT06521879
- Testing
- Lactobacillus plantarum 299v probiotic support
- Where
- Turkey (Türkiye)
- Volunteers
- 295 people
- Sponsor
- Antalya Training and Research Hospital
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