Clinical trials: Dietary Supplementation
Aging, Supplementation
Aquatic Power Training Dosing Strategies and Creatine Supplementation in Older Adults
This randomized controlled trial will investigate the effects of different aquatic power training dosing strategies and creatine supplementation on functional and multisystem adaptations in community-dwelling older adults.
- Conditions
- Aging, Supplementation, Exercise
- Trial name
- NCT07914270
- Testing
- Time-Based Aquatic Power Training + Creatine, Sedentary Control + Creatine
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Valencia
Non-alcoholic Fatty Liver Disease
Prebiotic Fibre Supplementation and Gut Microbiota in Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) is a condition where accumulation of fat in the liver leads to metabolic dysfunction. Currently there are no approved treatments for NAFLD.
- Trial name
- NCT02568605
- Testing
- Prebiotic fibre, Weight Loss
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Calgary
The Effects of Sodium Bicarbonate Supplementation on Endurance Performance in Recreational Female Runners
Sodium Bicarbonate Intake on Endurance Performance
Sodium bicarbonate (SB) is one of the ergogenic aids that enhance short-duration, high-intensity sports performance by improving the buffering system.
- Trial name
- NCT06826222
- Testing
- Sodium Bicarbonate (NaHCO3), Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cell Migration, Cell Invasion
This Repeated Measures Parallel-group Investigation Will Examine the Influence of Short-term Melatonin Supplementation (5mg, 3 x Day for 72 Hours) on Cellular Responses, Functional Performance and Recovery Following an Acute Bout of Dynamic Resistance Exercise in Resistance Trained Men and Women
Oral Melatonin is a commercially available product available alone and as a constituent in a number of supplements. Previous research suggests that short-term supplementation with oral melatonin may amplify the recovery response…
- Conditions
- Cell Migration, Cell Invasion, Exercise Recovery
- Trial name
- NCT06617351
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Vitamin B 12 Deficiency
Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation
Vitamin B12, a vital nutrient, plays a crucial role in red blood cell formation, neurological function, and DNA synthesis. Deficiency in B12 can lead to anemia, neurological symptoms such as tingling or numbness, and cognitive…
- Trial name
- NCT06376591
- Testing
- Vit B12
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
ADHD
Single-dose Potassium Supplementation in Patients With ADHD for Whom the Anesthetic Lidocaine is Ineffective
Randomized, controlled, double-blind trial of the effect of a single dose of potassium on ADHD symptoms as measured by changes in measures of symptoms of ADHD correlated with the results of their Lidocaine Effectiveness Test.
- Trial name
- NCT03563573
- Testing
- Potassium Gluconate Oral Capsule
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- AlkaliDx, Inc.
Obesity and Overweight, Anemia, Iron-Deficiency
Different Efficacy of IFA Supplementation Among Obese and Non-obese Women
This clinical trial aims to learn if there is a relationship between OWT/OB and IDA in nonpregnant women of reproductive age and its impact on iron supplementation.
- Trial name
- NCT06622551
- Testing
- Iron-folic acid supplement
- Where
- Indonesia
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Griffith University
Sarcopenia in Elderly, Malnourished
The Effects of MediDrink Platinum+ and Fava Bean Protein Hydrolysate on Fitness in an Aged Population
Examining the effects of MediDrink Platinum+ containing novel protein blend SRP-01 alone or when combined with PeptiStrong on clinical responses in elderly adults with sarcopenia
- Conditions
- Sarcopenia in Elderly, Malnourished, Protein Supplementation, Muscle Mass
- Trial name
- NCT07322653
- Testing
- MediDrink Platinum+, MediDrink Platinum+ and PeptiStrong
- Where
- 2 sites in Hungary
- Volunteers
- 75 people
- Sponsor
- Nuritas Ltd
Cancer
Effects of Nutritional Supplementation (Product 4808) on Acute Skeletal Muscle Protein Synthesis in Cancer Patients
The purpose of the study is to compare two different nutritional supplements with respect to their effect on building muscle, and to determine the factors that control the rate at which muscle tissue can be produced in subjects…
- Trial name
- NCT00446888
- Testing
- Standardized Meals for Diet Stabilization, Forticare, Product 4808
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arkansas
Influenza Vaccine Response
Effect of Oral Supplements for Influenza Vaccine Response
The aim of this clinical trial is to explore the efficacy of fatty acid and bile acid based supplements on enhancing influenza vaccine immune response in adults aged 60-70 years. The objectives of this study are: 1.
- Trial name
- EOSIIVE-RCT (NCT06827873)
- Testing
- ARA (Arachidonic Acid) Supplementation, TUDCA (Tauroursodeoxycholic Acid) Supplementation, Shanghai Biological Quadrivalent Influenza Virus Inactivated Vaccine
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Sodium Bicarbonate
Effect of Sodium Bicarbonate on Exercise Performance
This was a randomized, double-blind, placebo controlled, crossover trial. The study aimed to assess the effect of sodium bicarbonate on the ability to perform a repeated sprint task by female football players.
- Trial name
- NCT06098794
- Testing
- Sodium Bicarbonate
- Where
- Portugal
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Chronic Arsenic Poisoning
Vitamin E Level in Buccal Cells of Arsenicosis Patients
To understand the pathogenesis of chronic arsenic toxicity, the investigators need to know the levels of vitamin E in patients chronically exposed to high concentration of arsenic and if changes are found, what happens when…
- Trial name
- NCT01743066
- Testing
- Vitamin E
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Carpal Tunnel Syndrome (CTS)
Comparative Outcomes of Endoscopic and Open Carpal Tunnel Release with Neurotrophic Supplementation in Severe Carpal Tunnel Syndrome
This study addresses the pressing clinical question of optimizing surgical and pharmacological interventions for severe Carpal Tunnel Syndrome (CTS), a prevalent and debilitating condition caused by median nerve compression.
- Trial name
- NCT06902831
- Testing
- Endoscopic Carpal Tunnel Release, Open carpal tunnel release, Neurotrophic supplementation
- Where
- Italy
- Volunteers
- 497 people
- Sponsor
- University of Bari
Glomerular Disease
Vitamin D Supplementation in Glomerular Disease
This multi-site, pilot study will assess vitamin D supplementation in children and young adults with Glomerular Disease. .
- Trial name
- NCT01835639
- Testing
- Cholecalciferol, 2000 or 4000 IUs by mouth daily for 12 weeks
- Where
- 5 sites in United States
- Volunteers
- 32 people
- Sponsor
- Children's Hospital of Philadelphia
Gluten Sensitivity, Wheat Sensitivity
Effects of a Probiotic Supplementation on Symptoms and Microbiome Characteristics in Patients With Non-celiac Gluten/Wheat Sensitivity.
The aim of this randomized, double-blind, placebo-controlled clinical trial is to investigate the effects of probiotics on symptoms and gut microbiota composition following gluten reintroduction.
- Trial name
- NCT06884241
- Testing
- Probiotic supplementation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Turin, Italy
Healthy
Forearm Immobilization, Metabolic Health, and Muscle Loss
The present study will investigate the impact of altered substrate availability on muscle atrophy, insulin sensitivity and muscle protein synthesis following short-term forearm immobilization
- Trial name
- NCT03866512
- Testing
- Forearm immobilization
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Aortic Stenosis, Iron-deficiency
Iron Supplementation in TAVI and SAVR Patients With Iron Deficiency
The INERTIA trial is a multicenter double-blinded randomized trial of intravenous iron supplementation in patients with severe aortic stenosis and iron deficiency undergoing TAVI or SAVR.
- Trial name
- INERTIA (NCT04786769)
- Testing
- Ferric carboxymaltose
- Volunteers
- 2,500 people
- Sponsor
- Hospital de Santa Cruz, Portugal
Hepatocellular Carcinoma, Liver Function
Effects of Vitamin D Status and Multiple Mega-dose Supplementation on Health Care Disparities in Perioperative Patients With Hepatocellular Carcinoma Receiving Hepatectomy
High concentrations of parathyroid hormone (PTH) are common in patients with hepatocellular carcinoma (HCC). This study is aimed to investigate effects of vitamin D status and its multiple mega-dosage supplementation on PTH and…
- Conditions
- Hepatocellular Carcinoma, Liver Function, Postoperative Complications
- Trial name
- NCT05887505
- Testing
- Vitamin D
- Volunteers
- 120 people
- Sponsor
- Taoyuan General Hospital
Muscle Wasting, End Stage Renal Disease on Dialysis
Muscle Status to Oral Nutritional Supplementation in Hemodialysis Patients With Protein Energy Wasting
This multi-centred randomized, open label-controlled trial consists of hemodialysis (HD) patients identified with protein energy wasting (PEW) using the International Society of Renal Nutrition and Metabolism criteria.
- Trial name
- NCT04789031
- Testing
- Oral nutritional supplementation (ONS)
- Volunteers
- 54 people
- Sponsor
- Taylor's University
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