Clinical trials: Dietary Supplementation
Hypertension
Watermelon Supplementation and Arterial Stiffness
Increased abdominal obesity (waist circumference) and systolic blood pressure (BP) are main risk factors for the metabolic syndrome. Approximately 60% of adults in the United States are prehypertensive or hypertensive.
- Trial name
- NCT01185041
- Testing
- Watermelon Extract
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida State University
Resistance Exercise
Exercise and Galactooligosaccharide Supplementation on Inflammation and Iron Absorption (FexerGOS)
Iron depletion is common in female athletes depending on the sports discipline. Endurance and resistance exercise can induce inflammation thereby reducing dietary iron absorption.
- Trial name
- FexerGOS (NCT06038656)
- Testing
- Galactooligosaccharides (GOS)
- Where
- South Africa
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
HIV Infections, Substance-Related Disorders
The Effects of Nutritional Supplementation and Drug Abuse on HIV
The purpose of this trial is to determine whether supplementation with multivitamins and selenium will delay disease progression in HIV infected individuals in Botswana.
- Trial name
- NCT00149656
- Testing
- Multivitamins, Selenium
- Where
- Botswana
- Volunteers
- 878 people
- Sponsor
- Florida International University
Neurodevelopmental Abnormality
ASPIRIN: Neurodevelopmental Follow-up Trial
A total of 620 children will be enrolled in this study from six sites in sub-Saharan Africa, South Asia, and Latin America. Half of the children's mothers will have taken aspirin and half will have taken placebo.
- Trial name
- NCT04888377
- Testing
- Aspirin
- Where
- 14 sites in United States, Democratic Republic of the Congo and 4 more
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Hypertension
Whole Soy and Daidzein on Reduction of Blood Pressure in Postmenopausal Chinese Women
The investigators hypothesize that whole soy or purified daidzein alone could reduce blood pressure and CVD risks in equol-producing menopausal Chinese women.
- Trial name
- NCT01270737
- Testing
- Whole soy (soy flour), daidzein, milk powder
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
ADHD
Single-dose Potassium Supplementation in Patients With ADHD for Whom the Anesthetic Lidocaine is Ineffective
Randomized, controlled, double-blind trial of the effect of a single dose of potassium on ADHD symptoms as measured by changes in measures of symptoms of ADHD correlated with the results of their Lidocaine Effectiveness Test.
- Trial name
- NCT03563573
- Testing
- Potassium Gluconate Oral Capsule
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- AlkaliDx, Inc.
Denutrition
Effectiveness and Cost of a Quantitative and Qualitative Nutritional Supplementation in Elderly Patients
Evaluation of the effectiveness and the costs of a quantitative and qualitative nutritional supplementation in elderly patients
- Trial name
- NCT00560729
- Testing
- Renutryl 500, Generique, Generique + Renutryl 500
- Where
- 3 sites in France
- Volunteers
- 63 people
- Sponsor
- Société des Produits Nestlé (SPN)
Erectile Dysfunction
The Effects of a Nitrate Supplementation on Erectile Function
Twenty (20) individuals to be recruited from Ballantyne Medical Associates in Charlotte, NC, without any significant chronic medical history. These patients are general patients for primary care that meet inclusion criteria.
- Trial name
- NCT06213077
- Testing
- Nitric Oxide, Tadalafil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RHA Investments Ltd
Obesity
Evaluation of Fructans Supplementation on Parameters of Metabolic Syndrome
Obesity is constantly increasing, causing an important risk to develop diseases such as heart disease, diabetes,... Some recent studies have shown that obese people present modifications of colon microflora and a low-grade…
- Trial name
- FRUCTOB (NCT00616057)
- Testing
- Synergy 1, maltodextrin
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Pyruvate Kinase Deficiency, Glucose 6 Phosphate Dehydrogenase Deficiency
High-Dose Vitamin C in G6PDA and Pyruvate Kinase Deficiency: A Safety Study
This study is testing whether high-dose Vitamin C is safe and well-tolerated in patients with two inherited red blood cell disorders - Pyruvate Kinase Deficiency (PKD) and Class A Glucose-6-Phosphate Dehydrogenase Deficiency…
- Trial name
- G6PDA PKD (NCT07612345)
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Nutrition, Critical Illness
Micronutrients in Critically Ill Patients
Nutritional support is an important component of modern critical care. The practice of vitamin and micronutrient supplementation is variable and official guidelines are not consistent.
- Conditions
- Nutrition, Critical Illness, Vitamin Supplementation
- Trial name
- MiNuCrit (NCT04136119)
- Testing
- questionnaire
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Healthy Volunteers, Exercise Intensity
Combined Effect of Exercise Intensity With Nutritional Supplementation on Skeletal Muscle Function
The main objective of this study is to determine the effectiveness of a nutritional intervention (olive leaf extract) combined with a specific training session (MICT or SIT) on PDH activation (as well as other protein…
- Conditions
- Healthy Volunteers, Exercise Intensity, Neuromuscular Fatigue, Skeletal Muscle Adaptations
- Trial name
- NUTSPORT (NCT05350566)
- Testing
- Olive leaf extract
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Trained or Competitive Cyclists
Beet Root Supplement Trial
To examine the effects of two forms of beetroot juice supplementation on exercise performance in trained cyclists.
- Trial name
- NCT02010502
- Testing
- Beetroot juice, Beetroot powder
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Spinal Cord Injuries
Creatine or Vitamin D Supplementation in Persons With Spinal Cord Injury Undergoing Resistance Training
The purpose of this study is to determine the effects of creatine monohydrate or vitamin D supplementation on strength gains following a traditional resistance training program for adults with spinal cord injury.
- Trial name
- NCT02099357
- Testing
- Creatine, Vitamin D
- Where
- 2 sites in Portugal
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Gastrointestinal Health
The Impact of Postbiotic Supplementation on Tolerability and Physiological/Metabolic Parameters
This study aimed to evaluate whether daily postbiotic supplementation could improve gastrointestinal well-being and influence physiological and metabolic parameters in healthy young adults.
- Trial name
- PIProBaTo-II (NCT07893301)
- Testing
- Postbiotic Supplement
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Chronic Lung Disease
Nutritional Supplementation in Patients With Chronic Respiratory Disease
The aim of this study is to investigate the nutritional status of patients with chronic pulmonary disease undergoing regular outpatient pulmonary rehabilitation.
- Trial name
- NCT06112730
- Testing
- Standard pulmonnary rehabilitation, Nutritional supplementation intervention
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Fu Jen Catholic University
Hashimoto Disease, Treatment Levothyroxine
Effect of Treatment for Vitamin D Deficiency on Thyroid Function and Autoimmunity in Hashimoto's Thyroiditis.
The objective of this study is to evaluate the effect of vitamin D supplementation on thyroid autoimmunity, thyroid function, and other metabolic and clinical variables associated with the thyroid axis in patients with…
- Conditions
- Hashimoto Disease, Treatment Levothyroxine, Vitamin D Deficiency
- Trial name
- NCT04778865
- Testing
- Vitamin D-correction, Vitamin D-RDA
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Chronic Fatigue Syndrome
Creatine Supplementation in Chronic Fatigue Syndrome
This study evaluates the effectiveness of medium-term supplementation with creatine to improve clinical outcomes in well-defined adult CFS population.
- Trial name
- CREFAS (NCT02374112)
- Testing
- Creatine
- Volunteers
- 60 people
- Sponsor
- Center for Health Sciences, Serbia
Locally Advanced Gastric Adenocarcinoma
Effect of High Protein ONS on Older Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy
This interventional prospective randomized controlled study was conducted to compare the effects of high-protein oral nutritional supplement (ONS) and medical nutritional therapy to medical nutrition therapy alone on nutritional…
- Trial name
- NCT06645912
- Testing
- oral nutritional supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Erzincan Binali Yildirim University Mengucek Gazi Training and Research Hospital
Critically Ill
The Association of Vitamin D Supplementation With the Outcome in Critically Ill Children
Vitamin D deficiency is highly prevalent in critically ill adult and pediatric population that causes multiple adverse health outcomes including higher illness severity score, increased morbidity and mortality, multiple organ…
- Trial name
- NCT04536831
- Testing
- Vitamin D, Normal saline
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Dr Mustahsin Khalil
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