Clinical trials: Dietary Supplementation
Alzheimer Disease, Gut Microbiota
Design of Personalised SupplemenTs Based on the Gut MicRobiota Through Artificial Intelligence for Alzheimer's Patients
Studies indicate that the intestinal microbiota could have an implication in Alzheimer's disease; recently, a positive relationship has been established between levels of bacterial lipopolysaccharide (LPS) and cerebral…
- Trial name
- TREAT (NCT06199193)
- Testing
- Personalized diet, Dietary counseling
- Where
- 2 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Vitamin D Deficiency in Older Persons
Daily Vitamin D Supplementation Compared to a Loading Dose and Monthly Supplementation in Elderly Nursing Home Residents
Vitamin D deficiency is common in older persons, in particular in residents of nursing homes. This is mainly explained by the fact that older persons do not often go outside in the sunshine.
- Trial name
- VIDIV (NCT01168544)
- Testing
- loading dose Vitamin D and 50.000 IU vit D3/month, loading dose and 25.000 IU vit D3/month, Vitamin D 800 IU /day
- Where
- Netherlands
- Volunteers
- 160 people
- Sponsor
- Rijnstate Hospital
The Focus of the Study is to Investigate the Effects of Phosphatidylserine Supplementation on Exercise Physiology and Cycling Time-trial Performance
The Effect of Phosphatidylserine on Time Trial Performance in Trained Male Cyclists
Phosphatidylserine is a phospholipid found in high concentrations in the brain and nervous tissues along with naturally occurring in many foods.
- Trial name
- NCT04967404
- Testing
- Phosphatidylserine
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mark Glaister
Osteoporosis
Impact of Vitamin D Supplementation on Lactation Associated Bone Loss
Studies have shown that lactation is associated with a loss of bone density from four to seven percent at the spine and hip among women who lactate for six months. Decline in bone density with lactation occurs rapidly.
- Trial name
- NCT00903344
- Testing
- Vitamin D3, Multivitamin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Leigh Eck, MD
Cardiovascular Disease
Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk
The purpose of this study is to evaluate the effects of freeze dried strawberry powder on LDL cholesterol, central and peripheral blood pressure, indices of arterial stiffness, and other lipid and lipoprotein concentrations.
- Trial name
- NCT02557334
- Testing
- Low Dose Strawberry Powder, High Dose Strawberry Powder
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Penn State University
Sarcopenia in Elderly
Feasibility of Egg White Pudding Supplementation for Individuals in Personal Care Home Centres Needing Dietary Supplementation
This trial is an open-label randomized controlled parallel arm feasibility trial. 54 residents in care homes receiving nutrition supplementation (minimum 40% of each sex, ≥ 50 years of age).
- Trial name
- NCT07805993
- Testing
- Egg White Pudding, Nestle Resource
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seven Oaks Hospital Chronic Disease Innovation Centre
Pulmonary Disease, Chronic Obstructive, Dietary Supplements
Physical Capacity of Patients With Chronic Obstructive Pulmonary Disease With and Without Supplementation of Whey
Chronic obstructive pulmonary disease is characterized by obstruction to pulmonary airflow and dyspnea. These characteristics are a consequence of exposure to harmful gases and particles that lead to oxidative stress in the lungs…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Dietary Supplements, Rehabilitation
- Trial name
- NCT03386604
- Testing
- Whey protein, Maltodextrin
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hiv, Vaccine Reaction
B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV
The primary objectives of this study are to evaluate the effect of early-life B. infantis Rosell®-33 supplementation in infants exposed to HIV on: gut microbiome composition and diversity at 4 weeks of life markers of intestinal…
- Conditions
- Hiv, Vaccine Reaction, Microbial Colonization, Infant Development
- Trial name
- BifIID (NCT05923333)
- Testing
- B. infantis Rosell®-33
- Where
- South Africa
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Healthy Adult
Investigating the Impact of Probiotics on Wellbeing in a Community
The aim of this clinical trial is to investigate whether taking probiotics can improve thinking ability and digestive symptoms in healthy adults, and whether these effects depend on how often someone drinks alcohol.
- Trial name
- NCT07504952
- Testing
- Probiotic Arm
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Vitamin D Deficiency, Vitamin D Insufficiency
Vitamin D to Improve Nutrition Prior to Bariatric Surgery and Investigate the Relationship With Negative Outcomes
VISTA is looking to see if vitamin D supplements before bariatric surgery might improve vitamin D stores, which may help to prevent some complications like infections.
- Trial name
- VISTA (NCT02212652)
- Testing
- Vitamin D, Standard of Care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Chronic Kidney Disease, Vitamin D Deficiency
Effect of Vitamin D Supplementation on Coronary Calcification and Parathyroid Hormone in CKD Patients
The investigators hypothesize that the chronic kidney disease patients who suffer from vitamin D deficiency will be benefit from given Vitamin D2 because coronary artery calcification and hyperparathyroidism will be improved.
- Trial name
- EVIDENCE (NCT01672047)
- Testing
- Vitamin D2
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Peking University People's Hospital
Obesity & Overweight, Circadian Rhythm Disorders
Effects of Akkermansia Muciniphila and Berberine Supplementation on Insulin Sensitivity in Night-shift Workers
Night shift work is associated with an increased risk of obesity, insulin resistance, and cardiometabolic disorders, largely due to circadian misalignment, disrupted sleep, and altered eating patterns.
- Conditions
- Obesity & Overweight, Circadian Rhythm Disorders, Gut Microbiota Modulation, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
- Trial name
- Shift2Health (NCT07440147)
- Testing
- Verum (A)
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
Bifidobacterium
The Role of Bifidobacterium Animalis Ssp Lactis DR10 Supplementation in Women During Pregnancy and Lactation on Breast Milk IL-8 and Gut Mucosa Integrity in Infant
Hopefully this research can help to provide the optimal nutrition management from pregnancy so that the babies wiil born with better quality of health and reduce the morbidity and mortality.
- Trial name
- NCT02377544
- Testing
- Probiotic
- Where
- Indonesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Naomi Esthernita
Iron Deficiency Anemia, Iron-deficiency
Multiple Daily Condensed Tannin Supplementation and Iron Bioavailability: The Tannin Dose Response Trial
Tannins are known to inhibit iron absorption through formation of insoluble tannin-mineral complexes, and have thus been termed 'antinutritional.' Despite this, there is evidence that adaptation to similar antinutritional factors…
- Trial name
- NCT03030716
- Testing
- 95% condensed proanthocyanidins from grape seed extract
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Chronic Kidney Diseases
Effects of Jaboticaba (Plinia Cauliflora) Supplementation in Chronic Kidney Disease Patients
The increase prevalence of chronic kidney disease (CKD) over the years represent a significant public health problem. The role of inflammation and oxidative stress in the pathophysiology of CKD, as well as progression and…
- Trial name
- NCT06394531
- Testing
- Jaboticaba Peel Extract
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Vitamin D, Burn Injury
Effects of Cholecalciferol Supplementation on Bone Health and Muscle Strength in Adults During Post-burn Period
Vitamin D has pleiotropic effects. Burn patients are at risk of hypovitaminosis D and may experience post-injury osteopenia and sarcopenia.
- Trial name
- NCT02092701
- Testing
- Cholecalciferol
- Where
- Belgium
- Sponsor
- University of Liege
HDL, Health, Subjective
HDL Function Dietary Supplement Safety and QOL
Nutritional supplements are routinely purchased by consumers with suboptimal HDL to support their health, lifestyle and overall quality of life. Many such products receive minimal evaluation prior to marketing.
- Trial name
- NCT04097119
- Testing
- Dietary supplementation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Premature, Extremely Low Birth Weight Infants, Polyunsaturated Fatty Acid Levels
PUFA Supplementation in Premature Infants
The purpose of this study is to determine if buccal administration of a concentrated formulation of long-chain polyunsaturated fatty acids (LCPUFA) can help to maintain docosahexaenoic acid (DHA) levels in extremely low birth…
- Trial name
- NCT01955044
- Testing
- LCPUFA supplement
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Acute Watery Diarrhea
Comparison of Effectiveness of Zinc Supplementation With ORS and Bacillus Clausii Versus Zinc With ORS and Saccharomyces Boulardii in Acute Watery Diarrhea in Paediatric Patients
The current study was carried out to directly compare the effectiveness of zinc supplementation with ORS and Bacillus clausii versus zinc with ORS and Saccharomyces boulardii among the local pediatric population presenting with…
- Trial name
- NCT06540209
- Testing
- Bacillus clausii, Saccharomyces boulardii, Zinc
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- RESnTEC, Institute of Research
Hand Grasp
Magnesium Citrate Supplementation on Hand Grip Strength
The purpose of this research study is to determine the effectiveness of magnesium on handgrip strength using the more bioavailable magnesium citrate.
- Trial name
- NCT06091007
- Testing
- Magnesium
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
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