Clinical trials: Dietary Zinc Deficiency
Alcoholism
Examination of Zinc, S-adenosylmethionine, and Combination Therapy Versus Placebo in Alcoholics
This is a randomized, placebo controlled trial of dietary zinc and S-adenosylmethionine (SAMe) in otherwise healthy alcoholic US Veterans.
- Trial name
- ExZACTO (NCT01899521)
- Testing
- Bronchoscopy, Zinc sulfate 220 mg once daily, S-adenosylmethionine 400 mg twice daily
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- VA Office of Research and Development
Vitamin D Deficiency
The Effect of Combinatorial Nutritional Supplementation on Immune Function in Healthy Older Adults
Many older adults do not get enough zinc, vitamin C and vitamin D, and this can be related to decreased ability to fight infection.
- Trial name
- NCT02876315
- Testing
- Redoxon VI
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Zinc Deficiency
Dose Adjustment Study of NPC-02 in Patients With Zinc Deficiency
The objective of this study is to check the dose control method of NPC-02 and the holding effect for the target serum zinc concentration in patients with zinc deficiency.
- Trial name
- NCT02321865
- Testing
- NPC-02
- Where
- Japan
- Volunteers
- 43 people
- Sponsor
- Nobelpharma
Fractional Absorption of Zinc (Focus of the Study)
Zinc Absorption From Fortified Water
A water purifying system, called LifeStrawFamily (LSF), able to fortify water with zinc to a concentration of 4 mg/l has been developed.
- Trial name
- NCT01636583
- Testing
- LSF water without meal, LSF water and inhibitory meal, Fortified inhibitory meal with water
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Nutritional Deficiency
Bioavailability of Zinc and Iron From a Whey-based Protein Supplement Consumed With a Habitual Plant-based Diet
Bioavailability of iron and zinc from habitual plant-based diets consumed by young children in Mexico is low due to the high phytate content.
- Trial name
- NCT02208622
- Testing
- Study 1: Whey Supplement Day 1, Study 1: Whey Supplement Day 2, Study 2: Whey Supplement
- Where
- 2 sites in United States, Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Deficiency, Zinc Deficiency
Effect of Iron/Zinc-Biofortified Pearl Millet on Growth and Immunity in Children Aged 12-18 Months in India
In this study, iron- and zinc-biofortified pearl millet will be fed to young children in Mumbai, Maharashtra, India over a period of nine months to measure iron status, growth and immune function in comparison to children…
- Trial name
- NCT02233764
- Testing
- FeZnPM, CtrlPM
- Where
- 3 sites in India
- Volunteers
- 223 people
- Sponsor
- Cornell University
Preterm Infant, Effect of Drugs
Zinc Supplementation In Very Low Birth Weight Infants-A Randomised Controlled Trial
Zinc (Zn) is a structural component of human body and is a crucial element for a wide variety of cascades that take place in almost all organ systems.
- Conditions
- Preterm Infant, Effect of Drugs, Zinc Deficiency Disease
- Trial name
- NCT05311540
- Testing
- Zinc Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Weight Gain, Anemia, Iron Deficiency
Egg Intervention During Pregnancy in Indonesia
The study consists of two arms: 1) intervention group using eggs as supplementary food given from 2nd trimester of pregnancy to birth, and 2) observational group of pregnant mothers.
- Conditions
- Weight Gain, Anemia, Iron Deficiency, Birth Weight, Birth Length
- Trial name
- PRECODE (NCT04694235)
- Testing
- Egg intervention
- Where
- Indonesia
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
HIV, ART
Effect of Zinc and Selenium Supplementation on HIV+ Individuals on Antiretroviral Treatment.
The aim of this study is to evaluate the effect of zinc gluconate and/or selenium yeast supplementation during six months on clinical (glucose, cholesterol, triglycerides, bone mineral density and body composition) and…
- Conditions
- HIV, ART, Zinc Deficiency, Selenium Deficiency
- Trial name
- NCT03421314
- Testing
- Zinc gluconate and/or Selenium yeast
- Where
- Mexico
- Volunteers
- 37 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Zinc Deficiency
Clinical Trial to Determine the Bioavailability of Three Different Zinc Preparations
The main objective of this clinical is to get information on pharmacokinetics of zinc-enriched yeast.The bioavailability of the yeast enriched with zinc will be compared to two selected zinc salts used in food supplements that…
- Trial name
- NCT02292303
- Testing
- zinc-enriched yeast, Zinc references
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Lesaffre International
HIV, AIDS
Zinc Supplementation Effect on Immune Recovery in HIV Patients
INTRODUCTION: An adequate zinc supplementation is essential for a good immunological function. However, zinc deficiency is seen in more than 50% of adults infected with HIV.
- Conditions
- HIV, AIDS, Immunological Deficiency, Inadequate Immune Recovery
- Trial name
- NCT02162797
- Testing
- Zinc supplementation
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
Zinc Deficiency, Child Nutrition Disorders
Daily Zinc Supplement Effect on Prevention of Diarrhea and Acute Respiratory Infections in Children Less Than Five Years
Zinc deficiency in children is a major problem which leads to compromised immunity and accordingly repeated infections. This study aims to investigate the effect of supplementing zinc to decrease the incidence of diarrhea and…
- Trial name
- RCTZ (NCT05002101)
- Testing
- zinc
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Human Immunodeficiency Virus (HIV)
Repeat Doses of SB-728mR-T After Cyclophosphamide Conditioning in HIV-Infected Subjects on HAART
The purpose of this study is to evaluate the safety and tolerability of repeat doses of T-cell immunotherapy (SB-728mR-T) following cyclophosphamide conditioning. CCR5 is a major co-receptor for HIV entry into T-cells.
- Trial name
- NCT02225665
- Testing
- SB-728mR-T, Cyclophosphamide
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- Sangamo Therapeutics
Poliomyelitis
Effect of Zinc Supplementation on Response to Oral Polio Vaccine in Infants in Pakistan
Pakistan is one of the 4 developing countries where cases of poliomyelitis are still being identified. Despite the incessant efforts by WHO and UNICEF, this disease is far from control.
- Trial name
- NCT01229579
- Testing
- Zinc Sulfate
- Where
- Pakistan
- Volunteers
- 320 people
- Sponsor
- Aga Khan University
Zinc Deficiency
Impact of Mass Zinc Fortification Programs on Plasma Zinc Concentration
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of mass zinc fortification programs.
- Trial name
- NCT00944723
- Testing
- Zinc-fortified bread, Zinc supplement, Non-fortified bread
- Where
- Senegal
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Nutritional Deficiency
Zinc Bioavailability From Amaranth-enriched Maize Tortillas
Young children in Guatemala are at risk for nutrient deficiencies due to plant-based diets and poor sanitation. Stunting, frequent diarrhea, and respiratory infections are common.
- Trial name
- NCT02208609
- Testing
- Day 1: Maize Tortillas with 20% Amaranth, Day 2 Maize Tortillas without 20% Amaranth
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hiv
CD4 CAR+ ZFN-modified T Cells in HIV Therapy
This research study is being carried out to study a new way to possibly treat HIV. As part of this study, doctors will take some of your own white blood cells, called T-cells, and modify them so that they can identify and target…
- Trial name
- NCT03617198
- Testing
- CD4 CAR+CCR5 ZFN T-cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Zinc; Deficiency With Anemia
Zinc and Iron in Children With Short Stature
Short stature is defined as height below 3rd centile or less than two standard deviations below the median height for that age and sex according to the population standard zinc and iron have important role in growth for children
- Trial name
- zincandiron (NCT03131349)
- Testing
- serum zinc and iron
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vitamin A Deficiency, Iron-deficiency
Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Background: Micronutrient (MN) deficiencies are severe and widespread in West Africa, particularly among young children and women of reproductive age.
- Conditions
- Vitamin A Deficiency, Iron-deficiency, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- NCT05178407
- Testing
- Multiple micronutrient-fortified bouillon cube, Control bouillon cube (iodine-only)
- Where
- Ghana
- Volunteers
- 2,372 people
- Sponsor
- University of California, Davis
Zinc Deficiency
Zinc Deficiency in Dilated Cardiomyopathy
The aim of this study is to detect effect of oral zinc supplementation in pediatric patients with dilated cardiomyopathy.
- Trial name
- NCT04860921
- Volunteers
- 50 people
- Sponsor
- Assiut University