Clinical trials: Difference, Individual
Knee Osteoarthritis
The Effect of Theory-driven Physiotherapy on Physical Activity in Knee OA.
Knee osteoarthritis (OA) is a leading cause of pain, disability, and reduced physical functioning worldwide. Although physiotherapy and physical activity are recommended as first-line treatments, many individuals with knee OA do…
- Trial name
- EXPLOR (NCT07901881)
- Testing
- EXPLOR-3
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Mark van Loo
Diabetic Macular Edema
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
This study is open to adults with diabetic macular edema that involves the center of the eye. The purpose of this study is to find out how well different doses of a medicine called BI 3812465 are tolerated by people with this…
- Trial name
- NCT07553429
- Testing
- Low dose BI 3812465, Medium dose BI 3812465, High dose BI 3812465
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 49 people
- Sponsor
- Boehringer Ingelheim
Metastatic Prostate Cancer
A Study of Tarlatamab for People With Prostate Cancer
The researchers are doing this study to find out whether tarlatamab is an effective treatment for Delta-like Protein 3 (DLL3)-positive prostate cancer that has spread to other parts of your body (metastasized) and has either come…
- Trial name
- NCT07111507
- Testing
- Tarlatamab
- Where
- 10 sites in United States
- Volunteers
- 32 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bronchiectasis, Quality of Life
A Series of N-of-1 Trials of Traditional Chinese Medicine Based on Bayesian Method
The guiding role of parallel randomized controlled trials in clinical practice is limited due to the insufficiency of individual information.
- Conditions
- Bronchiectasis, Quality of Life, Traditional Chinese Medicine, Sputum
- Trial name
- NCT04601792
- Testing
- Individualized Decoction, Tested drug minus heat-clearing herbs
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Healthy
Individual Response to Different Volumes of Resistance Training
The literature is not clear as to which training volume to employ during initial phases of resistance training programs to ensure optimal muscular adaptations.
- Trial name
- NCT02179307
- Testing
- 12-week progressive strength training protocol
- Where
- Norway
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Type 2 Diabetes
A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes
The purpose of the study is to find out if the new tablet formulation oral semaglutide D is equally safe and effective as the approved oral semaglutide for treating Japanese people with type 2 diabetes.
- Trial name
- NCT07271251
- Testing
- Oral semaglutide
- Where
- 15 sites in Japan
- Volunteers
- 267 people
- Sponsor
- Novo Nordisk A/S
Human Immunodeficiency Virus, Tuberculosis
Preventive Therapy for Tuberculosis in HIV Infected Persons
Title: Evaluation of efficacy of two different preventive therapy regimens for tuberculosis in HIV infected persons Phase: Phase III trial Population: 650 HIV positive patients without tuberculosis Number of sites: Three 1.
- Trial name
- NCT00351702
- Testing
- Isoniazid with Ethambutol
- Where
- India
- Volunteers
- 683 people
- Sponsor
- Tuberculosis Research Centre, India
Chronic Kidney Disease
A Study to Test the Effect of Different Doses of Avenciguat (BI 685509) on Kidney Function in People With Chronic Kidney Disease
This study is open to adults who have kidney disease that is not caused by diabetes. The purpose of the study is to find out whether a medicine called avenciguat (BI 685509) improves kidney function.
- Trial name
- NCT04736628
- Testing
- Avenciguat
- Where
- 110 sites in United States, Argentina and 16 more
- Volunteers
- 261 people
- Sponsor
- Boehringer Ingelheim
Coronary Arterial Disease (CAD)
Central vs Brachial BP, Exercise, and Coronary Artery Disease
High blood pressure (BP) is a major risk factor for coronary artery disease (CAD), with 30-70% of CAD patients having elevated BP.
- Trial name
- NCT06617117
- Testing
- High-intensity combined exercise, Moderate-intensity combined exercise
- Where
- Portugal
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Parkinson Disease, Gait Disorders, Neurologic
Benefits of Different Exercise Types to Enhance Walking for PD
Background: Gait disturbance is one of the most common complaints from patients with Parkinson's disease (PD). It is well-established that people with PD have motor learning impairments.
- Trial name
- NCT04895787
- Testing
- Gait + aerobic exercise, Gait + resistance exercises, Gait + conventional physical therapy
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital
Sport Participation
Running Environments on Physiological Responses, Emotion, Motivation, and Attention
The goal of this clinical trial is to learn how different running environments affect physiological responses, emotional regulation, exercise motivation, and attentional control in healthy college students.
- Trial name
- NCT07494552
- Testing
- Indoor Treadmill Running Session, Outdoor Road Running Session, Outdoor Grass Running Session
- Where
- China
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Individual Difference
Increasing Individualism and Collectivism
An online survey is conducted on MTurk populations from India and USA. Participants were assigned either a condition with primes of individualism or one with primes of collectivism, before responding to a scale on culture and…
- Trial name
- NCT03429725
- Testing
- Online prime (statements writing), Online prime (circling), Online prime (Sumarian Warrior)
- Where
- Singapore
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Dairy Intolerance
Comparing the Digestion of Milk With Different Beta-casein Protein Content by Dairy Intolerant Persons
Persons with dairy intolerance may experience cramps/abdominal pain, bloating, flatulence, acute diarrhea, or fecal urgency when they ingest excessive amounts of lactose.
- Trial name
- NCT03713346
- Testing
- Lactose free milk, Jersey milk, High A1 β-casein milk
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Purdue University
Pertussis (Whooping Cough), Diphtheria
A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents)
the safety and tolerability of different dosages of adsorbed acellular pertussis (two-component) diphtheria-tetanus combined vaccine
- Conditions
- Pertussis (Whooping Cough), Diphtheria, Tetanus
- Trial name
- NCT07492303
- Testing
- Tdap vaccine
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Long COVID, Brain Fog
Effect of Probiotic Strain Lactobacillus Paracasei PS23 on Brain Fog in People With Long COVID
The goal of this clinical trial is to test whether the intervention of probiotics supplement can improve symptoms of long covid syndrome. Participants will be given probiotics or placebo capsules for two month.
- Conditions
- Long COVID, Brain Fog, Cognitive Change
- Trial name
- COVID-19 (NCT06348212)
- Testing
- Lactobacillus paracasei PS23, microcrystalline cellulose
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Shift Work Schedule, Sleep Deprivation
Quick Returns - Sleep, Cognitive Functions and Individual Differences
The project will contribute with new knowledge concerning how short rest periods between two consecutive shifts (<11h, often defined as a Quick Return (QR)) affects sleep and cognitive performance.
- Trial name
- NCT05162105
- Testing
- Short rest (8 hour) between two consecutive shifts., 16 hour rest opportunity between to consecutive shifts.
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Stroke
Understanding Different Parameters in Locomotor Training (a Type of Walking Training) for Person After a Stroke
This is a research study to understand how people who have experienced a stroke walk in order to develop better and more effective types of therapy.
- Trial name
- NCT00712179
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Parkinson Disease
A Study That Compares the Extent to Which Apomorphine Becomes Available in the Body After Taking Either an Investigational Drug Containing Apomorphine or Apomorphine That is Injected Under the Skin in People With PD Complicated by "OFF" Episodes
A study that compares the extent to which apomorphine becomes available in the body after taking either an investigational drug containing apomorphine or apomorphine that is injected under the skin in people with PD complicated…
- Trial name
- NCT03292016
- Testing
- APL-130277, APO-go, Apokyn
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- Sumitomo Pharma America, Inc.
Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy
The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders
People with Parkinson's disease (PD) commonly experience a range of both motor (e.g., bradykinesia, rigidity, tremor, and postural instability) and non-motor (e.g., fatigue, psychiatric and behavioural disturbances, autonomic…
- Conditions
- Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, Different Types of Tremor Including Essential Tremor, Dystonia
- Trial name
- NCT06174948
- Testing
- CUE1 non-invasive device
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Queen Mary University of London
Healthy, Obesity
A Study in People With Overweight or Obesity to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body
The primary objective of this trial is to assess bioequivalence of two formulations of survodutide (formulation A and formulation B6) after multiple-dose treatment in male and female trial participants living with overweight or…
- Conditions
- Healthy, Obesity, Overweight
- Trial name
- NCT07407348
- Testing
- Formulation A, Formulation B6
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim