Clinical trials: Difference, Individual
HIV Infection Primary
Assessing Differential Adherence to Medications and Quality of Life Among People Living With HIV and Comorbidities
The investigators propose to utilize quantitative and qualitative methodology to better understand the impact of multiple drug use (polypharmacy) on medication adherence as well as the driving forces behind differential adherence…
- Trial name
- TEAMH (NCT03387397)
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Severe Mental Illness, Schizophrenia
The Potential Efficacy of the Chinese Health Improvement Profile- A Pilot Clustered Randomised Controlled Trial
The investigators programme of research will evaluate an existing physical health care screening intervention with the aim of helping Community Psychiatric Nurses (CPN) to improve the physical health wellbeing of people with a…
- Conditions
- Severe Mental Illness, Schizophrenia, Schizoaffective Disorder, Bipolar Affective Disorder
- Trial name
- CHIP (NCT02453217)
- Testing
- Chinese CHIP, Treatment as usual
- Volunteers
- 144 people
- Sponsor
- Wai-Tong Chien
Appetite Self-regulation, Pediatric Obesity
Food Form & Energy Intake
This study primarily aims to examine how food presented in various forms (i.e., solid, semi-solid, and liquid) affects children's ability to self-regulate energy intake at a subsequent meal.
- Trial name
- NCT05258097
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Penn State University
Hypertension, Frailty
Can Frailty Inform the Management of Hypertension in Older People?
The purpose of this study was to investigate in large scale routine primary care data whether frailty is a prognostic factor for relevant outcomes in the management of hypertension in older people and whether frailty causes…
- Trial name
- Frail_BP (NCT04662203)
- Volunteers
- 145,598 people
- Sponsor
- University of Leeds
Obesity, Sedentary
Consistency in Individual Differences in Energy Intake Following Acute Exercise
The importance of exercise for weight control is well documented; however if exercise results in an increase in food intake, the beneficial effect of exercise may not be seen.
- Trial name
- NCT01645956
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Heat Stress, Heat Exposure
Validity of Humidity Ramp Protocols for Identifying Limits of Survivability in Heat-exposed Persons
The global populace is at growing risk of heat-related illness due to climate change and accompanying increases in the intensity and regularity of extremely hot temperatures.
- Conditions
- Heat Stress, Heat Exposure, Temperature Change, Body, Temperature; Extreme, Exposure
- Trial name
- NCT05963529
- Testing
- Humidity-ramp protocol, Above-inflection fixed-condition exposure, Below-inflection fixed-condition exposure
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Healthy
A Study in Healthy People to Compare How 2 Different Low Dose Formulations of BI 1015550 Are Taken up in the Body
The main objective of this trial is to establish the bioequivalence of the BI 1015550 Formulation C2 (Test, T) and the BI 1015550 Formulation C1 (Reference, R) following a single oral dose administration.
- Trial name
- NCT06408870
- Testing
- BI 1015550
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Human Immuno-deficiency Virus (HIV) Disease
A Study to Assess Change in Disease Activity, Adverse Events, and How the Drug Moves Through the Body in Adult Participants Living With Human Immunodeficiency Virus (HIV) Receiving Intravenous (IV) Infusion or Subcutaneous (SC) Injection of Budigalimab and/or ABBV-382
Human immuno-deficiency virus (HIV) is the virus that causes Acquired Immuno-Deficiency Syndrome (AIDS). HIV disease is considered to be a chronic disease requiring lifelong therapy.
- Trial name
- NCT06032546
- Testing
- Budigalimab, ABBV-382
- Where
- 80 sites in United States, Belgium and 11 more
- Volunteers
- 163 people
- Sponsor
- AbbVie
Parkinson's Disease
Feasibility and Acceptability of a Physical Activity Behavior Change Intervention for Parkinson's Disease
The purpose of this study is to assess the feasibility, in regards to acceptability and implementation, of the Pre-Active PD intervention for increased high intensity goal-directed aerobic exercise engagement in people with…
- Trial name
- Preactive-PD (NCT03696589)
- Testing
- Physical Activity Coaching
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Teachers College, Columbia University
Complex Sensorimotor Disabilities
Evaluation of Different Visual Keyboard Organizations on People With Complex Sensorimotor Disabilities
comparison of different visual keyboard configurations
- Trial name
- SK4All (NCT06876480)
- Testing
- Keyboard
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Contraceptive Usage, Contraceptive Behavior
A Web-Based Tool to Help People With Health Conditions Make Contraceptive Decisions
Among people who do not want to get pregnant, some do not use any birth control. This is also called contraceptive nonuse. Common reasons for contraceptive nonuse include concerns about birth control safety or side effects.
- Conditions
- Contraceptive Usage, Contraceptive Behavior, Chronic Disease, Chronic Condition
- Trial name
- NCT07075536
- Testing
- My Health, My Choice Web-Based Contraceptive Decision Tool, Usual Contraceptive Care
- Where
- 19 sites in United States, Puerto Rico
- Volunteers
- 795 people
- Sponsor
- University of Michigan
HIV Infections
Anti-HIV Activity and Safety of 3 Different Doses of Mifepristone in HIV Infected People
The purpose of this study is to determine the anti-HIV activity and safety of 3 different doses of mifepristone (also known as VGX-410 and RU486) in HIV infected people.
- Trial name
- NCT00099645
- Testing
- Mifepristone
- Where
- 10 sites in United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Frail Elderly
High Intensity Interval Training Versus Moderate Intensity Continuous Training in Frail Elderly
The assessment and systematic integration of physical activity into the care pathway of frail elderly people is essential to prevent loss of independence and improve the quality of life of this population.
- Trial name
- EPAF (NCT07211334)
- Testing
- Exercise Training
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Grenoble
Depression, Multiple Chronic Conditions
An Approach to "Move a Little & Often" With Health Conditions
People with long term conditions such as diabetes and arthritis, and who also have depression spend a lot of time sedentary during the day. This is because they face many barriers to being active, such as pain and fatigue.
- Trial name
- NCT03537053
- Testing
- A plan to Move a Little and Often
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Manchester
HIV Infections
Phase IV, a Clinical Trial to Assess Safety and Convenience of the Change From DTG/3TC to BIC/FTC/TAF in People With HIV, Good Virological Control and Neuropsychiatric Vulnerabilities
In people infected with HIV, with suppressed HIV viral load and receiving treatment with DTG/3TC: The change to BIC/FTC/TAF will decrease the development of adverse events of neuropsychiatric etiology.
- Trial name
- MIND (NCT05549180)
- Where
- 14 sites in Spain
- Volunteers
- 84 people
- Sponsor
- Fundacion SEIMC-GESIDA
COVID-19 SARS-CoV-2 Infection
A Phase III Clinical Trial to Evaluate the Efficacy and Safety of SCTV01E in Healthy People
The objective of this study is to evaluate the effectiveness of SCTV01E in healthy people
- Trial name
- NCT05683561
- Testing
- CoronaVac, SCTV01E
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Solid Tumors
A Study to Evaluate the Safety and Effectiveness of Different Doses of RO7836748 Alone or in Combination With Other Cancer Therapies in People With Solid Tumors With a Rat Sarcoma Viral Oncogene Homolog Glycine 12 Valine (RAS G12V) Mutation
The study will evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary clinical activity of RO7836748 as monotherapy and in combination with other anti-cancer therapies, including…
- Trial name
- NCT07905924
- Testing
- RO7836748, Pembrolizumab, mFOLFIRINOX
- Volunteers
- 540 people
- Sponsor
- Hoffmann-La Roche
Atherosclerosis
Effect of Atorvastatin and Lifestyle Intervention on Progression of Pre-Clinical Atherosclerosis
The purpose of this study is to determine whether atorvastatin, aggressive lifestyle intervention, and their interaction are effective in delaying the progress of pre-clinical atherosclerosis.
- Trial name
- EALIPPCA (NCT00723320)
- Testing
- Atorvastatin, Aggressive lifestyle intervention
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Musculoskeletal Disorders
PRISM: The PRimary Care Individual Social Norms MSK Data Dashboard: a Feasibility Trial
Background: 20 million people in UK have musculoskeletal (MSK) aches and pains. They commonly see their GP about this problem, but practices are so busy that it can mean a long wait for appointments.
- Trial name
- PRISM (NCT07112508)
- Testing
- PRISM dashboard is a data report, THe usual care intervention is a first contact physiotherapy service.
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University College, London
KINESIOTAPING
Effect of Kinesiotaping in Different Directions on Muscle
The study was conducted to investigate the effects of different Kinesio taping directions on dynamic muscle endurance. This randomized, double-blind, crossover study was implemented on 27 healthy male subjects.
- Trial name
- NCT04379674
- Testing
- FACILITATION TAPING, INHIBITION TAPING
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University