Clinical trials: Difficulty Breathing
Aging Disorder
Physical Impairments in Elderly Individuals
There are no studies in the literature reporting the dyspnea, posture, strength, physical activity, functional mobility and balance in elderly individuals.
- Trial name
- NCT06267625
- Testing
- Physical Evaluations of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Acute Respiratory Distress Syndrome
Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS)
ARDS (Acute Respiratory Distress Syndrome) is a condition of severe inflammation and excess fluids in the lungs that impairs their function of oxygen uptake to the point of needing a ventilator (breathing machine) to help them…
- Trial name
- NCT00446706
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Breathlessness, Quality of Life
Structured Exercise Training Programme in Idiopathic Pulmonary Fibrosis
In this single centre non-randomised pilot cohort study we wish to quantify the effect of a twice weekly, 8 week, structured responsive exercise training programme on exercise tolerance, symptoms and health related quality of…
- Conditions
- Breathlessness, Quality of Life, Idiopathic Pulmonary Fibrosis
- Trial name
- Rehab-IPF (NCT03222648)
- Testing
- Structured Responsive Exercise Training, Usual Care
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Respiratory Distress Syndrome, Acute, Severe Community-Acquired Pneumonia
Multimodal Database and Large Language Model for ARDS
The goal of this observational study is to integrate existing clinical cohorts from the research team to establish dedicated cohorts for ARDS and high-risk ARDS patients (primarily SCAP patients), then systematically collect…
- Trial name
- NCT06973733
- Testing
- Clinical data and biospecimen collection
- Volunteers
- 6,500 people
- Sponsor
- China-Japan Friendship Hospital
Acute Respiratory Failure, Acute on Chronic Respiratory Failure
Treatment of Dyspnea in Do-not-intubate Patients
Patients with severe chronic diseases are often admitted to the hospital complaining of shortness of breath. Some of these patients decide that they do not want placement of a breathing tube in the windpipe to assist their…
- Conditions
- Acute Respiratory Failure, Acute on Chronic Respiratory Failure, Dyspnea
- Trial name
- NCT02114944
- Testing
- NIV, CPAP, Standard oxygen
- Where
- 2 sites in United States, Italy
- Volunteers
- 400 people
- Sponsor
- Tufts Medical Center
Dyspnea; Cardiac
Test-Retest Reliability of Cardiopulmonary Exercise Testing With Echocardiography
CPETecho is progressively employed in diagnostic settings for pathophysiological detection, offering comprehensive assessment of both pulmonary and cardiac functions.
- Trial name
- REPEATCPETecho (NCT07281534)
- Testing
- CPETecho
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Bronchopulmonary Dysplasia
Point of Care Lung Ultrasound in Preterm Infants With Respiratory Distress
The goal of this observational study is to learn about the role of bedside lung ultrasound in infants born prematurely with breathing problems.
- Trial name
- NCT05925075
- Testing
- Lung Ultrasound
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Phoenix Children's Hospital
Intensive Care Unit Syndrome, Intensive Care Neuropathy
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO).
- Conditions
- Intensive Care Unit Syndrome, Intensive Care Neuropathy, Intensive Care (ICU) Myopathy, Acute Respiratory Distress Syndrome
- Trial name
- CLEVERER (NCT03753412)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
ARDS
NMR Based Metabolomics Kinetics in ARDS Patients
Acute respiratory distress syndrome (ARDS) is a life-threatening condition requiring respiratory support to maintain oxygenation.
- Trial name
- NCT06036056
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Hypoxemic Acute Respiratory Distress, Infant Between 1 Month and 24 Months Old
Automatic Oxygen Administration During the Respiratory Distress in Infants and Children (Infant-FreeO2)
The aim of the study is to assess the use feasibility of the FreeO2 system so as to deliver automatically oxygen in infants and children admitted at hospital for hypoxemic acute respiratory distress.
- Conditions
- Hypoxemic Acute Respiratory Distress, Infant Between 1 Month and 24 Months Old, Child Between 2 and 15 Years Old
- Trial name
- Infant-Free02 (NCT02302183)
- Testing
- FreeO2 v2.0 automatic adjustment, FreeO2 v2.0 data collecting
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
ARDS, Human
Clinical Study of Titrating PEEP of Different Methods on Right Heart Function
To observe the influence of different methods titrating PEEP on right heart function and pulmonary artery pressure in ARDS patients .
- Trial name
- NCT03845556
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Southeast University, China
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
Cerebral Bleeding in COVID-19 ARDS Patients on Veno-venous ECMO
Critically ill patients with severe acute respiratory distress syndrome (ARDS) sometimes require treatment with veno-venous extracorporeal membrane oxygenation (ECMO) to support gas exchange.
- Conditions
- Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication, Corona Virus Infection
- Trial name
- NCT04853953
- Testing
- Incidence of bleeding complications in ARDS patients on veno-venous ECMO
- Volunteers
- 400 people
- Sponsor
- University of Zurich
COVID-19
Pulmonary Vascular Dysfunction as a Cause of Persistent Exertional Dyspnea After Coronavirus Disease (COVID-19)
To identify pulmonary vascular disease in post/long-COVID-19 patients as a cause of dyspnea/exercise limitation and to differentiate it from other causes of dyspnea
- Trial name
- PulmVasC (NCT05374577)
- Testing
- pulmonary vascular dysfunction, pulmonary vascular function
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Giessen
Acute Respiratory Distress Syndrome (ARDS), Cardiogenic Shock
Cerebral Autoregulation in Pediatric ECMO (ECMOX 2)
Children supported by Extra-Corporeal Membrane Oxygenation (ECMO) present a high risk of neurological complications and cerebral autoregulation (CA) impairment may be a risk factor.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Cardiogenic Shock, Cardiac Arrest
- Trial name
- ECMO-ECMOX2 (NCT04548739)
- Where
- 4 sites in France, Italy
- Volunteers
- 132 people
- Sponsor
- Nantes University Hospital
COPD
The Effect of Fluticasone/Salmeterol Combination on Exertional Breathlessness in Patients With Mild COPD
Even patients with milder COPD can have significant physiological abnormalities which become more pronounced during exercise, leading to intolerable breathing discomfort (dyspnea).
- Trial name
- NCT00559312
- Testing
- fluticasone/salmeterol combination
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Queen's University
Foreign Body in Oropharynx
Foreign Body Swallows in Pediatrics
Foreign Body Ingestion (FBI) is a common clinical emergency in children. Most FBs smoothly pass through the digestive tract without complications; nevertheless, some FBs can cause severe morbidity and mortality.
- Trial name
- NCT05253027
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Bahaa Mohammed Refaie
Bronchopulmonary Dysplasia
Trial II of Lung Protection With Azithromycin in the Preterm Infant
The hypothesis of this study is that administration of azithromycin to ventilated premature infants will decrease the incidence and severity of BPD.
- Trial name
- NCT00319956
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Hubert Ballard
ARDS, Human
Evaluation of Von Willebrand Factor as a Marker For Early Diagnosis of Acute Respiratory Distress Syndrome (A.R.D.S) in Comparison to Interleukin 6 [IL-6]
In this prospective study of 60patients, we tested the hypothesis That markedly elevated levels of plasma von Willebrand factor (VWF) a marker of endothelial cell injury might predict the development of acute respiratory distress…
- Trial name
- NCT04317469
- Testing
- VWF measurement
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Acute Respiratory Failure
Physiological Effects of a New Interface on Lung Ventilation and Gas Distribution
Hypoxemic Acute Respiratory Failure (hARF) is a common reason of admission to Intensive Care. Different modalities can be used to administer oxygen, which is the first supportive treatment in these patients.
- Trial name
- NCT04619641
- Testing
- High Flow Nasal Cannula (HFNC), Continuous Positive Airway Pressure (CPAP)
- Volunteers
- 15 people
- Sponsor
- University Magna Graecia