Clinical trials: Digestive System Surgical Procedures
Colorectal Cancer, Surgery
Cardiopulmonary Exercise Test Data Averaging Methods and Preoperative Risk Assessment
Cardiopulmonary exercise testing (CPET) is used for preoperative risk assessment in patients with colorectal cancer who need to undergo surgery.
- Conditions
- Colorectal Cancer, Surgery, Colorectal Neoplasms Malignant
- Trial name
- NCT05353127
- Testing
- CPET/Cardiopulmonary Exercise Test
- Where
- Netherlands
- Volunteers
- 21 people
- Sponsor
- VieCuri Medical Centre
GERD
A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors
Background: Gastroesophageal reflux disease (GERD), which affects at least 20% of adult Americans, may be especially common and severe in Veteran patients.
- Trial name
- NCT01265550
- Testing
- Nissen fundoplication, baclofen, Desipramine
- Where
- 15 sites in United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neuromuscular Blockade, Intraoperative Bleeding
Bleeding in Laparoscopic Liver Surgery
Blood loss during liver resection surgery affects patients morbidity, short and long-term mortality. Among non-surgical interventions to minimize intraoperative blood loss and perioperative blood products transfusion, maintaining…
- Conditions
- Neuromuscular Blockade, Intraoperative Bleeding, Hepatic Cancer
- Trial name
- MODELS (NCT04609410)
- Testing
- Neuromuscular blockade
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Università Vita-Salute San Raffaele
Colorectal Cancer
CRC Post-surgical Assessment and Recurrence Monitoring
The surgical therapeutic effect of stage II-IV CRC patients will be assessed by the plasma mSEPT9 assay, and patients will be followed up by the same assay for recurrence monitoring.
- Trial name
- NCT03334890
- Testing
- plasma mSEPT9 level
- Where
- 4 sites in China
- Volunteers
- 50 people
- Sponsor
- BioChain (Beijing) Science and Technology, Inc.
Surgical Training, Residency
Laparoscopic Elective Colorectal Procedures Performed by Supervised Residents Are Safe and Sufficient.
The ability to perform laparoscopic colorectal surgery is an essential attribute of a general surgeon. Data on the participation of residents and the outcomes of colorectal procedures performed by surgeons in training are in…
- Trial name
- NCT06622720
- Testing
- surgery
- Where
- Poland
- Volunteers
- 498 people
- Sponsor
- Jagiellonian University
Colorectal Neoplasms, Diverticulitis
Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery
This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery.
- Conditions
- Colorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases, Surgical Site Infection
- Trial name
- NCT03042091
- Testing
- Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Thomas Jefferson University
Liver Cancer, Pancreatic Cancer
Postoperative Thoracic Epidural Analgesia Versus Intravenous Patient-Controlled Analgesia For Liver and/or Pancreas
The goal of this clinical research study is to learn if there is a difference in patients' quality of recovery if they receive 1 of 2 standard kinds of pain control treatments after surgery on the liver and/or pancreas.
- Trial name
- NCT01438476
- Testing
- Intravenous Patient-Controlled Analgesia (IVPCA), Thoracic Epidural Analgesia (TEA), Questionnaires
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- M.D. Anderson Cancer Center
Gastrointestinal Neoplasms
The Use of a OCT Probe in Assessment of Endoscopic and Surgical Resection Specimen of Gastrointestinal Tract
This is a pilot study aiming to investigate the ability of a novel Optical Coherence Tomography (OCT) probe in assessing the different layers of the gastrointestinal tract and the depth of invasion of early neoplasia, utilising…
- Trial name
- NCT04670718
- Testing
- Optical Coherence Tomography Probe
- Where
- Hong Kong
- Volunteers
- 8 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer, Colorectal Cancer
Satisfaction & Efficacy of Compression Using Surgical Gloves in Chemo-induced Peripheral Neuropathies
Evaluation of Satisfaction \& Efficacy of Compression Using Surgical Gloves in Peripheral Neuropathies Due to Chemotherapy
- Trial name
- ELEGANT (NCT03872908)
- Testing
- Chilled gloves, Surgical gloves
- Where
- 2 sites in France
- Volunteers
- 177 people
- Sponsor
- Centre Leon Berard
Acute Pancreatitis
Enhanced Recovery in Acute Pancreatitis
Prospective randomized-controlled trial evaluating impact of enhanced recovery protocol compared to standard care for recovery of patients with acute pancreatitis.
- Trial name
- ASERT (NCT02813876)
- Testing
- Enhanced recovery protocol
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Kaiser Permanente
Robotic Gastrectomy, Stomach Neoplasms
Carina™ Surgical Platform for Minimal Radical Gastrectomy
To evaluate the safety and effectiveness of the laparoscopic surgical system（Carina™ Surgical Platform, developed by Ronovo Surgical, Inc) for use in gastrectomy.
- Trial name
- NCT07113340
- Testing
- Carina™ Surgical Platform, developed by Ronovo Surgical, Inc
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Acute Calculous Cholecystitis
GALLVIA Trial: EUS-Guided vs Transpapillary Gallbladder Drainage for Acute Calculous Cholecystitis
This multicenter, prospective, open-label, randomized controlled trial compares endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) with endoscopic transpapillary gallbladder drainage (EGBS) in poor surgical candidates…
- Trial name
- GALLVIA (NCT07536191)
- Testing
- Endoscopic Ultrasound-Guided Gallbladder Drainage, Endoscopic Transpapillary Gallbladder Drainage
- Where
- 5 sites in Japan
- Volunteers
- 90 people
- Sponsor
- Aichi Medical University
Rectal Neoplasms
Selection of Surgical Technique in Rectal Cancer
Currently, there is no prediction scale available to identify patients with rectal neoplasms as technically complex in the middle and lower thirds; that is, those who are at high risk of affected circumferential margins and low…
- Trial name
- TECARE (NCT06442215)
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 333 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Pancreatic Fistula, Pancreaticoduodenectomy
Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic Fistula
Postoperative pancreatic fistula (POPF) is a major complication and an important cause of mortality after pancreaticoduodenectomy (PD).
- Conditions
- Pancreatic Fistula, Pancreaticoduodenectomy, Complication of Surgical Procedure
- Trial name
- NCT04989868
- Testing
- Trans-Nasal Afferent Loop Decompression, Without Trans-Nasal Afferent Loop Decompression
- Where
- China
- Volunteers
- 299 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Pancreatic Neoplasms, Rectal Neoplasms
Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer
This study will evaluate light therapy used in combination with standard therapies for pancreatic and rectal cancer. Participants will receive chemotherapy, radiation, and surgical treatments identical to that they had not been…
- Trial name
- NCT06164691
- Testing
- Blue light, Amber light, Ambient White Light
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Matthew Neal MD
Colorectal Neoplasms
Effect of TroVax in Patients Having Colorectal Cancer With Liver Metastases Removed
This study will test the safety and efficacy of TroVax in patients undergoing surgical resection of colorectal cancer with liver metastases.
- Trial name
- NCT00259844
- Testing
- TroVax
- Volunteers
- 20 people
- Sponsor
- Cancer Research UK
Gastric Cancer
Curative D2 vs D1 Lymphadenectomy in Operable Gastric Carcinoma
Gastric carcinoma is the second most common cause of cancer-related deaths and its main treatment modality if potentially curable is surgery but the optimal surgical resection is controversial.
- Trial name
- NCT04340440
- Testing
- D1 lymphadenectomy, D2 lymphadenectomy
- Volunteers
- 80 people
- Sponsor
- University of Alexandria
Gallbladder Disease, Biliary Colic
Fluorescence Imaging on the da Vinci Surgical System for Intra-operative Near Infrared Imaging of the Biliary Tree (up to 2-weeks Post-operatively)
The investigators hypothesize that the da Vinci Fluorescence Imaging Vision System provides real-time endoscopic near infrared fluorescence imaging of the biliary anatomy as defined as identifying biliary vessels; either cystic…
- Conditions
- Gallbladder Disease, Biliary Colic, Gallstones
- Trial name
- NCT01410734
- Testing
- Indocyanine green (ICG)
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 72 people
- Sponsor
- Intuitive Surgical
Endoscopic Surgical Procedure
Percutaneous Sigmoid Fixation For Management Of Recurrent Sigmoid Volvulus
The investigators included all patients who were presented to emergency department with recurrent sigmoid volvulus at Zagazig University hospital between (August 2024 to August 2025).
- Trial name
- NCT07155304
- Testing
- percutaneous sigmoid colon fixation
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Heart; Surgery, Heart, Functional Disturbance as Result
Multifunctional Approach in Cardiac Surgery
Postoperative pain and swallowing disorders are complex, multifactorial phenomenon that frequently occur after cardiac surgery. Preoperative anxiety and the interaction between sex and other sociocultural factors may predict…
- Trial name
- TITANIC (NCT05824598)
- Testing
- Multifunctional rehabilitation treatment
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS