Clinical trials: Digestive System Surgical Procedures
Liver Neoplasms, Hepatectomy
Hypovolemic Phlebotomy to Reduce Blood Transfusions in Major Hepatic Resections
Major liver resection is associated with substantial intraoperative blood loss and subsequently blood transfusions. Blood transfusion in elective liver surgery is a significant factor of perioperative morbidity and mortality, as…
- Conditions
- Liver Neoplasms, Hepatectomy, Blood Transfusion, Blood Loss, Surgical
- Trial name
- PRICE2 (NCT03651154)
- Testing
- Hypovolemic Phlebotomy
- Where
- 4 sites in Canada
- Volunteers
- 440 people
- Sponsor
- Ottawa Hospital Research Institute
Liver Cancer
Feasibility of a Minimally Invasive Image-Guided Surgery System for Hepatic Procedures
This study was designed to confirm that the surgeon is able to perform accurate liver surface registration including standard liver features used as landmarks during a scheduled laparoscopic liver procedure.
- Trial name
- NCT01238653
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Pathfinder Therapeutics
Obesity, Bariatric Surgery
Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
This is a two-site randomized clinical trial aiming to test whether a modified investigational bariatric surgical procedure can improve gastroesophageal reflux disease (GERD) after sleeve gastrectomy.
- Conditions
- Obesity, Bariatric Surgery, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
- Trial name
- INNOVATE-VSG (NCT06783751)
- Testing
- Modified Vertical Sleeve Gastrectomy (mVSG), Conventional Vertical Sleeve Gastrectomy (cVSG)
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- University of California, Irvine
Obesity, Gastric Cancer
Effect of Obesity on Surgical Outcomes and Survival for Gastric Cancer
As the number of obesity continues to increase, surgical oncologist pay more attention to the effect of obesity on surgical outcomes and survival of digestive systemin cancers.
- Trial name
- NCT02800005
- Testing
- AFA group (successive patients), BMI group (successive patients)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Jian-Kun Hu
Rectal Cancer, Quality of Life
Quality of Life in RECTal Cancer - a Prospective Multicenter Cohort Study
Rectal cancer is a common type of cancer occuring more frequently in men but also common in women. Almost 60% of the patients survive 5-years and the treatment has been continuously developed in the last three decades.
- Conditions
- Rectal Cancer, Quality of Life, Surgery
- Trial name
- QoLiRECT (NCT01477229)
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Sahlgrenska University Hospital
Achalasia
A Prospective Study Comparing Two Reconstructive Operation Techniques After Myotomy of Achalasia
Achalasia is a rare motor disorder of the gastroesophageal junction which is associated with an increased pressure of the esophageal sphincter. This leads to impairment to swallow and heartburn.
- Trial name
- NCT01933373
- Testing
- Toupet, Dor
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska University Hospital
Gallstone, Cholecystitis
A Clinical Study of Chinese Domestic Surgical Robot
This is a prospective, multi-center, randomized, single-blind, parallel-controlled clinical trial to evaluate the safety and efficacy of the Chinese domestic endoscopic instrument control system in clinical treatment.
- Trial name
- NCT04122261
- Testing
- the MicroHand S endoscopic instrument control system, the da Vinci endoscopic instrument control system
- Where
- China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Liver Cancer, Adult
AI-Driven Quantitative Decision and Surgical Planning System for Liver Cancer
This study aims to develop and validate an integrated AI-powered system for liver cancer that includes intelligent tumor boundary detection, micro-metastasis prediction, staging, treatment decision-making, and surgical planning.
- Trial name
- NCT07042841
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Crohn Disease, Colorectal Cancer
Colorectal Cancer in Crohn's Disease
Retrospective multicentre study. All patients with a diagnosis of Crohn's disease (CD) and operated for colorectal cancer (CRC) between 01/01/2010 and 01/01/2020 will be included in the dataset.
- Conditions
- Crohn Disease, Colorectal Cancer, Inflammatory Bowel Diseases
- Trial name
- NCT04654494
- Testing
- Total proctocolectomy, Total colectomy, Segmental colectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Rome Tor Vergata
Advanced Pancreatic Adenocarcinoma, Pancreatic Adenocarcinoma
Resistance Training Intervention to Improve Physical Function in Patients With Pancreatic Cancer Receiving Combination Chemotherapy or Have Undergone Surgery, PancStrength Study
This clinical trial studies the safety of a real-time tele-exercise resistance training (training done using a tablet) in maintaining skeletal muscle, strength, physical function, and health-related quality of life in patients…
- Conditions
- Advanced Pancreatic Adenocarcinoma, Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8
- Trial name
- NCT04837118
- Testing
- Educational Intervention, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Neoplasm Malignant Head Primary
A New Anatomical Classification of Portal Vein Location of Pancreas Tumors
In this retrospective study, we recorded the location of pancreatic tumors and relation/proximity to the portal vein. The surgical difficulty and requirement of additional interventions were also evaluated.
- Trial name
- NCT04416685
- Testing
- primary repair, segmental resection, graft reconstruction
- Volunteers
- 43 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Fistula in Ano
Two Approaches to Lower the Chances of Recurrence of Anal Fistula After Surgery
A total of 80 patients with complex fistula in ano of both genders were included. All patients in Group A underwent a loose seton technique.
- Trial name
- NCT06380036
- Testing
- video assisted fistula tract surgery
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sairah Sadaf
Nephrostomy; Complications, Pneumoperitoneum
A Trial Comparing Deep Versus Moderate Neuromuscular Block - in Low Pressure Pneumoperitoneum
Live kidney transplantation is first choice for patients with end-stage kidney disease. Therefore, the safety and well-being of kidneys donors are highly important objectives in live kidney donation.
- Conditions
- Nephrostomy; Complications, Pneumoperitoneum, Observation of Neuromuscular Block
- Trial name
- LEOPARD-3 (NCT02602964)
- Testing
- Deep neuromsucular block
- Where
- Netherlands
- Volunteers
- 34 people
- Sponsor
- Radboud University Medical Center
Acute Kidney Injury, Pneumoperitoneum
The Effect of Pneumoperitoneum (Raised Pressure in the Peritoneal Cavity) During Robotic Kidney/Prostate Cancer Surgery.
Within all the surgical specialties, major surgeries are performed whenever possible, as minimally invasive procedures to reduce blood loss, reduce pain and discomfort after surgery, avoid major scars, provide a faster recovery…
- Conditions
- Acute Kidney Injury, Pneumoperitoneum, Kidney
- Trial name
- NCT04755452
- Testing
- Low intra-abdominal pressure, High (standard) intra-abdominal pressure
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aalborg University Hospital
Colonic Neoplasms, Pain, Postoperative
The Effect of Methods of Self-regulation of Mental State on Pain Perception in the Postoperative Period in Colon Cancer Patients
In this study, it will be investigated whether the methods of self-regulation of mental state have an effect on postoperative pain perception in colon cancer patients.
- Conditions
- Colonic Neoplasms, Pain, Postoperative, Hypnotherapy
- Trial name
- NCT05708872
- Testing
- Autohypnosis, Relaxing music
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Colon Cancer
Intracorporeal Anastomosis Versus Extracorporeal Anastomosis for Left Colon Cancer
This study aims to investigate the effects of intracorporeal anastomosis and extracorporeal anastomosis in laparoscopic-assisted radical left hemicolectomy on surgical site infection.
- Trial name
- NCT04201717
- Testing
- laparoscopic assisted left colectomy (extracorporeal anastomosis group), total laparoscopic left colectomy (intracorporeal anastomosis group)
- Where
- 12 sites in China
- Volunteers
- 350 people
- Sponsor
- Jilin University
Inflammatory Bowel Diseases
Assessing Cardiovascular Dysfunction Pre- & Post-treatment in Inflammatory Bowel Diseases
The aim of this study is to compare medical and surgery treatment in IBD patients and healthy controls, by assessing the endothelial and cardiac function and the inflammation status.
- Trial name
- NCT03615287
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Athens
Gastric Cancer
Standardization of D2 Lymphadenectomy and Surgical Quality Control: KLASS-02-QC
Gastric cancer is one of the most common cancers in Korea. Having achieved excellent long-term survival for early gastric cancer patients, there is a growing interest in improving the quality of life of these patients without…
- Trial name
- NCT01283893
- Testing
- Laparoscopic distal gastrectomy with D2 lymphadenectomy
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Yonsei University
Peritoneal Carcinomatosis
Peritoneal Carcinomatosis Extent Evaluation: Radiologic, Laparoscopic and Pathologic.
pathologically proved ovarian cancer patients that underwent contrast enhanced abdomino-pelvic CT and diagnostic laparoscopy before cytoreductive surgery (CRS) will be included in the study.
- Trial name
- NCT03798132
- Testing
- laparoscopy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Shimaa Abdalla Ahmed
Crohns Disease, Fistula
Study to Look at Benefit of Surgical Drainage Before Beginning Medical Therapy for Crohns Perianal Fistulas
This study is looking at the advantage of establishing surgical drainage for Crohn's fistulas and abscesses prior to starting medical therapy.
- Conditions
- Crohns Disease, Fistula, Abscess
- Trial name
- NCT01145365
- Testing
- Exam under anesthesia (EUA)
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt University Medical Center