Clinical trials: Digital
Systemic Sclerosis
Open-Label Study of Oral Treprostinil in Digital Ulcers
This open label extension trial will allow ongoing treatment of subjects who participated in the randomized controlled trials, and will provide long term information about the safety of treprostinil diethanolamine SR in subjects…
- Trial name
- DISTOL-EXT (NCT00848107)
- Testing
- treprostinil diethanolamine
- Where
- 26 sites in United States, Canada and 1 more
- Volunteers
- 115 people
- Sponsor
- United Therapeutics
Ulcer, Acral Nevus
Effectiveness of the EmoLED Medical Device in the Healing of Digital Ulcers in Patients With Scleroderma.
The present clinical study aims to compare, in the two groups of patients with acral ulcers, the reparative process of the injured area, the evaluation of the healing time (with "healing" interpreted as the complete…
- Conditions
- Ulcer, Acral Nevus, Scleroderma, Digital Ulcer
- Trial name
- SUITABLE (NCT05181644)
- Testing
- EmoLED treatment, current Standard of Care
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Emoled
Digital Nerve Injury
NeuraGen 3D Pilot Study
This is a 10-subject, 12-month follow-up, prospective, multi-center, open-label, single arm clinical trial designed to understand the initial performance characteristics and confirm the safety profile of the NeuraGen 3D Nerve…
- Trial name
- NCT05343143
- Testing
- NeuraGen 3D Nerve Guide Matrix
- Where
- 4 sites in United States
- Volunteers
- 1 people
- Sponsor
- Integra LifeSciences Corporation
Digital Competences, Emotional Intelligence
Digital Literacy and Emotional Intelligence and Professional Burnout Among Doctors
The role of digital technologies in healthcare is growing. Therefore, the roles and responsibilities of medical professionals are constantly changing and there is a need for continuous professional development.
- Conditions
- Digital Competences, Emotional Intelligence, Emotional Burnout, Doctor Patient Relation
- Trial name
- NCT06349187
- Testing
- Interview
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- Limited Liability Company "Docstarclub"
Blended-care Counselling, Digital and Mental Literacy Training
Prevention Programme for Improvement of Well-being and Level of Participation in Adolescents With Enhanced Psychiatric Burden in the School Environment.
The objectives of this two-arm phase-IIa randomized, controlled study are: to prove whether the combination of a clinic-guided personal counseling with a therapy-assistive digital support (blinded care approach) and a training of…
- Conditions
- Blended-care Counselling, Digital and Mental Literacy Training, App STEPS
- Trial name
- STEPS@SCHOOL (NCT06390384)
- Testing
- blinded-care counselling, App STEPS, digital and mental literacy training
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Diet Modification, Hypertension
DASH Cloud: Using Digital Health to Improve Adherence to the DASH Diet Among Women
This study will test whether a digital health intervention (DASH Cloud) using smartphones can improve diet quality among women at risk for cardiovascular disease.
- Conditions
- Diet Modification, Hypertension, Women's Health, Cardiovascular Diseases
- Trial name
- NCT03215472
- Testing
- DASH Cloud, Nutritionix Track app
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Duke University
Venous Thromboembolism, Clinical Decision Support Systems
Smart Technology Facilitated Venous Thromboembolism Prophylaxis Based on Bundled Evidence-based Prevention Strategies
Venous thromboembolism (VTE) is the third leading cause of cardiovascular disease deaths globally, and its incidence is increasing over the years.
- Conditions
- Venous Thromboembolism, Clinical Decision Support Systems, Digital Health
- Trial name
- SmaVTE-BEST (NCT06353373)
- Testing
- Application of the modified DeVTEcare system
- Volunteers
- 15,626 people
- Sponsor
- Navy General Hospital, Beijing
Implementation; Digital Health, Chronic Insomnia
Optimizing the Scalability of Evidence-Based Behavioral Sleep Medicine Practices With a Digital Health Platform
The purpose of this study is to compare three different ways to deploy a clinician-decision support platform called NOCTEM COAST among behavioral health care providers who encounter patients with insomnia.
- Trial name
- NCT04366284
- Testing
- No Facilitation Support, External Facilitation Support, External and Internal Facilitation Support
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Noctem, LLC
Pancreas Adenocarcinoma, Endoscopic Ultrasound
Digital Confocal Microscopy for Real-time Diagnosis of Pancreatic Solid Lesion
Endoscopic ultrasound-guided (EUS) tissue acquisition is the current standard of care for the diagnosis of pancreatic solid lesions but it is burdened by a non-negligible risk of non-diagnostic or inconclusive results.
- Conditions
- Pancreas Adenocarcinoma, Endoscopic Ultrasound, Digital Pathology
- Trial name
- Multi-RELAMI (NCT06315439)
- Testing
- Endoscopic ultrasound fine needle biopsy
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Campus Bio-Medico University
Application of Digital Therapeutic in Lung Cancer Whole Process Management
Effects of Digital Therapeutic in Whole Process Management of Lung Cancer
This trial will randomize patients into two groups, the treatment group will use the digital therapeutic application named 'UHealth' for the whole process management and the control group will use regular follow-up.
- Trial name
- NCT06230445
- Testing
- UHealth digital therapeutic
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Sun Yat-sen University
Painful Digital Neuroma
Treatment of Painful Digital Neuroma Using A Pedicled Nerve Flap
Neuroma excision and digital nerve reconstruction remain the best option for the treatment of Painful Digital Neuroma (PDN). When the distal nerve end is preserved, conventional nonvascularized nerve grafting is the primary…
- Trial name
- NCT01684839
- Testing
- Pedicled nerve flap
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Prostate Disease, Elevated Prostate Specific Antigen
MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer
This research study is designed to determine if targeted Magnetic Resonance Imaging (MRI) Ultrasound (US) fusion biopsy is better than the standard of care ultrasound guided biopsy alone in diagnosing subjects with clinically…
- Conditions
- Prostate Disease, Elevated Prostate Specific Antigen, Family History of Prostate Cancer, Positive Digital Rectal Exam
- Trial name
- NCT04599218
- Testing
- Prostate Biopsy, MR US Fusion Guided Prostate Biopsy, MR/TRUS Fusion Guided Prostate Biopsy
- Where
- 3 sites in United States
- Volunteers
- 1,586 people
- Sponsor
- Ardeshir Rastinehad
Nerve Injury, Digital Pulp Defect
Free Dorsal Digital Flap for Reconstruction of Volar Soft Tissue Defect of Digits
The aim of the current report is to investigate the feasibility of transferring the free dorsal digital flap, including both dorsal branches of the proper digital nerves (PDNs), to reconstruct the volar soft tissue defect of…
- Trial name
- NCT01533337
- Testing
- Free dorsal digital flap
- Volunteers
- 12 people
- Sponsor
- The Second Hospital of Tangshan
New-generation Digital PET/CT Imaging
Feasibility Assessment of Next-generation PET Technology and Procedures
The purpose of this study is to assess the feasibility of investigational Positron Emission Tomography (PET) imaging using the new generation digital detector PET technology for new procedures beyond the current standard of care.
- Trial name
- NCT03387618
- Testing
- Digital PET/CT imaging
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- University of Cincinnati
Climate Change, Interactive Digital-based Educational Program
Interactive Digital-based Educational Program and Climate Change
Nursing's climate action position may shift from a white and wealthy world to a more inclusive one. Nurses in Egypt and elsewhere have found resonance with this method of campaigning, pressing their employers to implement…
- Conditions
- Climate Change, Interactive Digital-based Educational Program, Rural Nurses
- Trial name
- NCT06196476
- Testing
- Interactive digital-based educational program
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Digital Education Interventions, Knowledge Types (Mechanistic Versus Procedural)
Digital Delivery of Patient Education: A Case Study of Symptom Self-Management During Cancer Treatment
The increasing shift from face-to-face to online patient-clinician encounters in the healthcare system requires patients to be more involved in their medical care.
- Trial name
- NCT06187610
- Testing
- Digital education
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Tel Aviv University
Digital Technology, Dental
Accuracy of Tooth Modified Scan Bodies as a Novel Technique
The clinical performance of a novel scan body Tooth Modified Scan Body (TMSB) in the degree of trueness of IOS impression for full arch cases. I
- Trial name
- NCT06177782
- Testing
- Tooth modified scan bodies, Conventional scan bodies
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Orthodontics, Bracket Bonding
Indirect Bonding Accuracy of 3D Printed Digital Transfer Trays
The goal of this study is to compare the bracket transfer accuracy of two frequently used 3D printed indirect bonding trays. This is an interventional study. Participants have 3-6mm crowding without tooth loss and deformity.
- Conditions
- Orthodontics, Bracket Bonding, Indirect Bonding, Digital Indirect Bonding Transfer Tray
- Trial name
- NCT06167278
- Testing
- Indirect bonding with two different digital bracket bonding transfer tray
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Scleroderma, Digital Ulcer
Effectiveness of Bosentan Therapy in Patients With Systemic scleRosis and Progressive Digital ulcEr Disease.
Digital Ulcers (DEs), are painful open sores on the fingers and toes and are due to limited perfusion of blood vessels in patients with Scleroderma.
- Conditions
- Scleroderma, Digital Ulcer, Autoimmune Diseases, Diffuse Cutaneous Systemic Sclerosis
- Trial name
- CURE (NCT05168215)
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Hypovolemic Shock, Cardiogenic Shock
Digital Ischemia Reduction in Critically Ill Patients
Patients requiring high dose pressors (minimum 2) who are unlikely to be weaned off them over 1 day will be identified. Patients will have the device applied to one hand while expectant medical management will continue to the…
- Conditions
- Hypovolemic Shock, Cardiogenic Shock, Digital Ischemia
- Trial name
- DIR (NCT05661773)
- Testing
- the combined use of vacuum assisted suction and heat exchanger warming
- Sponsor
- Wake Forest University Health Sciences