Clinical trials: Digital
Soft Tissue Defect of the Finger
A Comparison of Dorsal Branch of the Digital Nerve Versus Dorsal Digital Nerve for Finger Pulp Reconstruction
As the donor nerve attached with the flap, the dorsal branch of the digital nerve and the dorsal digital nerve is commonly used for finger pulp reconstruction.This study compares two donor nerves: the dorsal branch of the digital…
- Trial name
- NCT01826539
- Testing
- flap includes a donor nerve
- Where
- China
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Major Depressive Disorder
The Effects of Videogames on Depression Symptoms and Brain Dynamics
The purpose of the study is to evaluate the effects of a game-based digital-therapeutics (DTx) medical software device on the symptoms of depression in adults with confirmed major depressive disorder.
- Trial name
- NCT05426265
- Testing
- MEL-T01, MEL-S01
- Where
- 6 sites in Finland
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Aalto University
Breast Cancer
Evaluation of the Efficacy of Digital Breast Tomosynthesis Imaging
The primary objective of this protocol is to collect the 2-dimensional (2D) screening and diagnostic images, and 3-dimensional (3D) Digital Breast Tomosynthesis (DBT) scans from patient mammography examinations acquired on…
- Trial name
- DBT (NCT01373671)
- Testing
- SIEMENS INSPIRATION DIGITAL BREAST TOMOSYNTHESIS (DBT) SYSTEM
- Where
- United States
- Volunteers
- 764 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions USA - CSG
Head and Neck Cancer
The Impact of Qigong on Quality of Life and Sleep Disturbance in Head and Neck Patients Undergoing Radiotherapy
This study aimed to observe how a six week qigong program influence patients with head and neck cancer during active radiotherapy treatment course.
- Trial name
- NCT03136575
- Testing
- Qigong, Wait-list control
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Hearing Disability, Depression
Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching
The purpose of this study is to see if a mobile-delivered mental health program called Toivoa-002, which combines digital cognitive behavioral therapy (CBT) with personal coaching, can effectively reduce depression in adults with…
- Conditions
- Hearing Disability, Depression, Mobility Disability
- Trial name
- NCT07195292
- Testing
- Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Toivoa Inc
Pancreas Neoplasm
Usefulness of 3D Digital Reconstruction in the Imaging Diagnosis of Pancreatic Tumors
Reconstruction using 3D virtual models has brought about a revolution in diagnostic imaging and its use is increasingly widespread.
- Trial name
- NCT04783844
- Testing
- Virtual modelization.
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Eye Disease
Digital Photography to Evaluate Dry Eye
Surface eye problems (problems of the cornea and conjunctiva), such as dry eye, are often evaluated using ocular surface staining - the application of a colored dye to the surface of the eye.
- Trial name
- NCT00073099
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Eye Institute (NEI)
Chronic Kidney Disease
INCLUDE-CKD: INCLUsive Digital carE for Chronic Kidney Disease
This study will provide valuable insights into the demographics of MyRenalCare users, their digital adherence, and the overall impact of the app on health outcomes, healthcare costs, and environmental sustainability.
- Trial name
- INCLUDE-CKD (NCT07613593)
- Testing
- Non-Interventional Study
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Breast Carcinoma
Research on the Whole-Process Intelligent Diagnosis and Treatment of Digital Breast Tomosynthesis Based on Deep Learning
This study aims to construct a multi-task deep learning model system to mine deep features in DBT images, so as to achieve accurate detection of breast lesions, differential diagnosis of benign and malignant (especially for the…
- Trial name
- NCT07605195
- Testing
- To explore the value of digital breast tomosynthesis based on deep learning in the diagnosis of breast cancer
- Volunteers
- 5,000 people
- Sponsor
- Yunnan Cancer Hospital
Overweight and Obesity
WW Improving Nutrition Study: A Randomized Controlled Trial
The main objective of this study is to determine whether a behavior change weight management and wellness program (WW) delivered via an app for 6-months will be effective in improving diet quality in U.S.
- Trial name
- WINS (NCT05648344)
- Testing
- WW, Control
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- Georgia Southern University
COVID-19
A Randomized Controlled Trial of a Digital, Self-testing Strategy for COVID-19 Infection in South Africa.
As the world opens up to rapidly increasing vaccination coverage and newer variants, there is an even greater need for timely access to at-home COVID-19 testing, or self-testing based out of kiosks, offices, or private spaces.
- Trial name
- NCT05436795
- Testing
- Abbott Panbio rapid antigen self-tests, COVIDSmart CARE! app
- Where
- South Africa
- Volunteers
- 600 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Mild Cognitive Impairment
Five Lives MED to Improve Cognitive Function in Mild Cognitive Impairment
The goal of this randomized controlled trial is to determine whether the digital health app Five Lives MED can improve cognitive function in people with mild cognitive impairment (MCI).
- Trial name
- NCT06598163
- Testing
- Five Lives MED
- Where
- 7 sites in France, United Kingdom
- Volunteers
- 170 people
- Sponsor
- SharpTx
Depressive Symptoms, Anxiety Disorders and Symptoms
Evaluating a Virtual Mentoring Program Plus Mental Health Videos for Teens
This clinical trial evaluates Appa Health, a mental health smartphone and computer app for teenagers. Appa is built from two components.
- Trial name
- NCT06138730
- Testing
- Appa Complete, Appa Lite
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Appa Health
Cancer
A Digital Art Activity to Enhance Self-Disclosure and the Detection of Psycho-social Distress in Adult Cancer Patients
To look at how a digital art activity may help cancer patients improve their ability to express their distress, symptoms, and lived experience.
- Trial name
- NCT06127121
- Testing
- Digital Art Activity
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- M.D. Anderson Cancer Center
Onset and Duration of a Digital Nerve Block
Determination of the Duration of Action of a Lidocaine and a Bupivacaine Digital Nerve Block in Human Volunteers
The duration of the autonomic (sympathetic) block will last longer than the sensory block. The duration of the increased perfusion index will last longer than either the sympathetic or sensory block.
- Trial name
- NCT01508832
- Testing
- Lidocaine Digital Nerve Block, Bupivacaine Digital Block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Psychosis, Anxiety
Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis
The aim of this trial is to evaluate the feasibility and preliminary efficacy of using passive smartphone sensors to detect moments of heightened negative mood and inform the timing of brief mental health interventions, such as…
- Conditions
- Psychosis, Anxiety, Depression, Rumination
- Trial name
- NCT07503093
- Testing
- Smartphone-based Mindfulness Exercise, Smartphone-based Psychoeducation, Neutral Control Message
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mclean Hospital
Depression - Major Depressive Disorder
Integrating Digital Phenotypes and AI-Driven Cognitive-Behavioral Therapy: Advancing Precision Medicine in Depression Through Digital Medicine
This project aims to integrate digital phenotyping and AI-driven iCBT into a comprehensive platform for MDD diagnosis and treatment in Taiwan.
- Trial name
- NCT07500714
- Testing
- Internet Cognitive-Behavioral Therapy
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Alcohol Misuse
The PSP Alcohol Reset Course
This observational study evaluates an internet-delivered cognitive behavioural therapy for alcohol misuse adapted for public safety personnel (PSP), called the PSP Alcohol Reset Course.
- Trial name
- NCT07873684
- Testing
- Self-Guided PSP Alcohol Reset Course
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Regina
Sepsis, Emergent Infections, Treatment
Droplet Digital PCR Combines With Transcriptome Analysis in Early Warning of Sepsis in the Emergency Department
Rapid identification of pathogens and early warning of host response are key to improve the prognosis of sepsis. Establishing a comprehensive identification system based on pathogen identification and host immune status is an…
- Trial name
- NCT06028178
- Testing
- Droplet digital PCR
- Volunteers
- 360 people
- Sponsor
- Shanghai East Hospital
Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM)
Pediatric Insulin Plan Calculator for T1DM Management
This is a multi-centre, prospective, randomized, open-label controlled trial designed to evaluate the effectiveness of a flexible digital insulin dose calculator in children under 12 years of age with Type 1 Diabetes Mellitus…
- Conditions
- Type 1 Diabetes Mellitus, Type 1 Diabetes Mellitus (T1DM), T1DM, T1DM - Type 1 Diabetes Mellitus
- Trial name
- FLEXI-T1D (NCT07427134)
- Testing
- Flexible Digital Insulin Dose Calculator
- Where
- 2 sites in Iraq, Pakistan
- Volunteers
- 440 people
- Sponsor
- Sultan Qaboos University
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