Clinical trials: Digital
Breast Cancer
Characterization of Extracellular Vesicles in Breast Cancer Patients
Extracellular vesicles (EVs) are lipid bilayer-delimited particles, naturally released from cells and mediators of intercellular cross-talk.
- Trial name
- NCT05798338
- Testing
- Blood sample
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Head and Neck Cancer
Digital Patient Education Platform in Head and Neck Cancer
Head and neck cancer is a disease that has a particular propensity for treatment-related morbidity. It is hypothesized that patients who are more involved in their care in hospital and who are actively provided with more…
- Trial name
- NCT05211778
- Testing
- Digital Education Group
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of British Columbia
Elder Abuse
Feasibility of VOICES Elder Abuse Intervention in Primary Care Setting (VOICES-PC Feasibility)
To test an interactive intervention to screen for Elder Abuse and Mistreatment (EM) in the Primary Care (PC) setting to promote self-identification and self-disclosure of EM.
- Trial name
- VOICES-PC (NCT05224843)
- Testing
- Virtual cOaching in making Informed Choices on Elder Mistreatment Self-Disclosure (VOICES)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia Spectrum and Other Psychotic Disorders
Feasibility and Outcomes of a Digital Health Support for the Schizophrenia Spectrum
This protocol describes an attempt to capture the development phase of a mobile support for individuals with schizophrenia. The intent is to describe and account for a rigorous development process that will result in the creation…
- Trial name
- NCT03649815
- Testing
- App4Independence
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Centre for Addiction and Mental Health
Cancer Colorectal, Frailty
Digital Home-Based Prehabilitation Before Surgery
This clinical trial compares two different prehabilitation programs, with no organized prehabilitation, prior to major colorectal cancer surgery.
- Conditions
- Cancer Colorectal, Frailty, Surgery
- Trial name
- dHOPE (NCT06231576)
- Testing
- Prehabilitation
- Volunteers
- 140 people
- Sponsor
- Vestre Viken Hospital Trust
Breast Cancer
Comparison of CE-DBT and MRI in Patients With Known Breast Lesions
The purpose of this pilot study is to compare radiologist confidence level in evaluating patients with known breast lesions between contrast enhanced digital breast tomosynthesis (CE- DBT) and contrast enhanced dynamic magnetic…
- Trial name
- NCT05754749
- Testing
- Iohexol 350 Mg/mL Injectable Solution
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Dementia, Lewy Body
ANeED Joint Effort 21: eHealth and a PPI Program in Dementia With Lewybodies (DLB)
The goal of the study is to develop predictive algorithms and digital biomarkers to capture disease fluctuations in (prodromal) dementia with lewybodies (DLB) patients and to improve treatment, diagnosis and prognosis of the…
- Trial name
- JointEffort21 (NCT05773443)
- Testing
- Digital biomarkers
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Bergen
Digital Nerve Injuries
Sensory Recovery of Digital Nerves After Microsurgical Epineural Neurorrhaphy Alone or in Combination With Tisseel - RET
Evaluation of sensitivity after primary surgical treatment of digital nerve injuries with microsurgical epineural end-to-end neurorrhaphy alone or in combination with the fibrin glue Tisseel®
- Trial name
- RET (NCT05490940)
- Testing
- Tisseel®
- Where
- Switzerland
- Volunteers
- 74 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Prostate Cancer
Hybrid Intelligence for Trustable Diagnosis and Patient Management of Prostate Cancer (HIT-PIRADS)
The purpose of this study is to develop a new way to diagnose prostate cancer through the use of artificial intelligence. The goal is for this new method to reduce delays in diagnoses and to avoid invasive procedures such as…
- Trial name
- HIT-PIRADS (NCT06804785)
- Where
- United States
- Sponsor
- Northwestern University
Mental Health Wellness 1
Digital Intervention to Promote Medical Trainee Well-being (OptimalWork Pilot)
This project aims to address stress, anxiety, burnout, and depression among medical trainees using a web-based intervention that teaches cognitive behavioral therapy (CBT)-based skills to increase resilience.
- Trial name
- NCT06914843
- Testing
- OptimalWork, Podcast Listening
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Loneliness, Self-Efficacy
Digital Storytelling-Based Psychoeducation for Loneliness and Self-Efficacy in Adults Aged 65-74
This study is testing whether a psychoeducation program developed using digital storytelling affects loneliness and self-efficacy in adults aged 65 to 74.
- Trial name
- NCT07878715
- Testing
- Digital Storytelling-Based Psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Şura KILIÇ
Child Development
Digital Support Systems to Improve Child Health and Development in Peru
About 250 million children under age five are at risk of not reaching their developmental potential due to continued exposure to ill health, malnutrition and lack of appropriate learning environments.
- Trial name
- DigitalECD (NCT05202106)
- Testing
- Home visits, Afini App
- Where
- 2 sites in Peru, Switzerland
- Volunteers
- 2,400 people
- Sponsor
- Swiss Tropical & Public Health Institute
Anxiety, Social Phobia
Efficacy of an App-based CBT Featuring Virtual Reality for Anxiety Disorders
Primary aim is to evaluate the efficacy of a (minimally) therapist-guided app-based psychotherapy with virtual reality exposure therapy (ALISA) in participants with agoraphobia with or without panic disorder, social anxiety…
- Conditions
- Anxiety, Social Phobia, Panic Disorder, Agoraphobia
- Trial name
- ALISA (NCT05510804)
- Testing
- ALISA
- Where
- 2 sites in Germany
- Volunteers
- 222 people
- Sponsor
- Bartosz of Zurowski
Systemic Sclerosis
Ultrasound Therapy and Manual Therapy in Digital Ischemic Ulcers
The objective of this before-after non-randomized trial study is to evaluate the efficacy of ultrasound therapy in combination with manual therapy in the management of systemic sclerosis patients with IDU.
- Trial name
- NCT05907200
- Testing
- combination ultrasound therapy and manual therapy, manual therapy
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- University of Palermo
Cardiovascular Diseases, Cardiovascular Morbidity
Assessment and Digital-health Based Intervention on Subclinical Organ Damage and Cardiovascular Risk in Chinese
To comprehensively evaluate subclinical organ damage of Chinese adults and its association with future cardiovascular disease and events.
- Conditions
- Cardiovascular Diseases, Cardiovascular Morbidity, Subclinical Organ Damage, Digital Health
- Trial name
- NCT05435898
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Shanghai 10th People's Hospital
Pain in Pediatric Dentistry, Dental Anxiety
Effectiveness of Digital Anesthesia Versus Conventional Techniques in Reducing Pain and Anxiety in Children
This multicenter randomized controlled clinical trial was conducted to evaluate the effectiveness of digital anesthesia using a computer-controlled intraosseous system (SleeperOne 5®) compared to traditional local anesthesia…
- Trial name
- DAPAED (NCT06992193)
- Testing
- Digital Anesthesia, Infiltration Anesthesia, Mandibular Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Ege University
Systemic Sclerosis, Scleroderma
Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine
This study will evaluate the effect of treprostinil diethanolamine (UT-15C) sustained release tablets(compared to placebo) on digital ulcers in patients with scleroderma. Treprostinil diethanolamine is an analog of prostacyclin.
- Trial name
- DISTOL-1 (NCT00775463)
- Testing
- treprostinil diethanolamine
- Where
- 30 sites in United States, Canada and 1 more
- Volunteers
- 148 people
- Sponsor
- United Therapeutics
Diabetes Mellitus, Type 2
SugarVita: a Digital Board Game
The serious digital game, SugarVita, is a collaborative effort between the Máxima Medical Centre (MMC) and Eindhoven University of Technology (TUe), intending to enhance self-management for individuals with diabetes.
- Trial name
- NCT06392178
- Testing
- SugarVita
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Obesity
HealthyWeightHub.fi: Web-based Management of Obesity in a Real-life Clinical Setting
This study evaluates the effectiveness of a web-based obesity management program HealthyWeightCoaching (HWC), within a HealthyWeightHub.fi (HWH) platform. HWC is a 12-month intervention within a real-life clinical setting.
- Trial name
- NCT04019249
- Testing
- Healthy Weight Coaching
- Where
- Finland
- Volunteers
- 6,000 people
- Sponsor
- Helsinki University Central Hospital
Covid19
Western Kenya Integrated COVID-19 Response
To respond to the COVID-19 pandemic, investigators will be deploying community health workers, equipped with mobile technology, and accompanied by youth to visit households door to door to screen for symptoms of COVID-19…
- Trial name
- NCT04501458
- Testing
- Training of youth, community health assistants and community health workers., Training clinicians in basic critical care and the management of severe COVID-19 cases
- Where
- Kenya
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Surgical Systems Research Group
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