Clinical trials: Digital
Myasthenia Gravis
Digital Phenotyping and Lifestyle Intervention in Patients with Myasthenia Gravis
Myasthenia Gravis (MG) is a chronic autoimmune neurological disorder where an antibody attack of muscle receptors causes fatigable skeletal muscle weakness. In addition to fatigue, several MG patients experience general fatigue.
- Trial name
- DIG-MG (NCT05992025)
- Testing
- Physical activity, Sleep hygiene
- Where
- Sweden
- Volunteers
- 83 people
- Sponsor
- Uppsala University
Visual Acuity
Non-Invasive Assessment of Contact Lens Performance During Use of a Digital Display
This is a two-arm, open-label, bilateral dispensing clinical investigation. Eligible subjects will proceed to either a low-sphere or high-sphere arm based on refraction measurements in the baseline assessment.
- Trial name
- NCT04869189
- Testing
- JJVC Marketed Contact Lens
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Peripheral Arterial Disease
Telerehabilitation in Patients With Peripheral Arterial Disease
This prospective longitudinal study evaluated the feasibility, adherence, and clinical and functional effects of a 6-month home-based telerehabilitation program in patients with peripheral arterial disease of the lower limbs.
- Trial name
- PAD_TR (NCT07825168)
- Testing
- Home-based telerehabilitation
- Where
- Romania
- Volunteers
- 42 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Breast - Female, Dense Breast Parenchyma
Evaluation and Reclassification of ( BI-RADS 3) Breast Lesions in Dense Breast
This prospective study aims to compare combined breast ultrasound (US) and digital mammography (DM) with digital breast tomosynthesis (DBT) in the evaluation and reclassification of BI-RADS 3 (probably benign) breast lesions.
- Conditions
- Breast - Female, Dense Breast Parenchyma, Breast Lesion, Digital Mammography
- Trial name
- NCT07804147
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Oncology
A Remote Evaluation of NAVIFY Oncology Hub Using Clinical Simulation
This work seeks to understand current clinical workflow practice and validate use cases for NAVIFY Oncology Hub. The main purpose of NAVIFY Oncology Hub is to enhance clinical and operational effectiveness, from diagnostic workup…
- Trial name
- NCT05478135
- Testing
- NAVIFY Oncology Hub
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Prova Health Limited
Arteriopathy Upper Limb, Renal Insufficiency
Evaluation of Macro and Microcirculatory Arterial Condition of the Upper Limb in Insufficiently Renal Patients
Evaluation of macro and microcirculatory arterial condition of the upper limb in insufficiently renal patients Hand ischemia affects 1.6 to 8% of patients with arteriovenous fistula (FAV) of hemodialysis in the upper limb.
- Conditions
- Arteriopathy Upper Limb, Renal Insufficiency, Digital Pressure
- Trial name
- SYSTOE-HAIDI (NCT04451018)
- Testing
- evaluation of arterial anomalies in upper limbs
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Grenoble
Atrial Fibrillation (AF), Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)
An AI-ECG-Based Approach for Dynamic Assessment of Heart Failure Risk and Myocardial Recovery Following Atrial Fibrillation Ablation
Background Artificial intelligence-enabled electrocardiography (AI-ECG) has emerged as a promising digital biomarker for detecting latent myocardial dysfunction and predicting cardiovascular risk.
- Trial name
- NCT07708818
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Postmenopausal Symptoms, Literacy
The Effect of Digital Literacy Education Given to Postmenopausal Women on Health Literacy and Quality of Life
During menopause, women may experience many conditions and symptoms due to fluctuation in hormone levels. These symptoms can affect a woman's social and personal functioning and quality of life.
- Conditions
- Postmenopausal Symptoms, Literacy, Quality of Life, Health Literacy
- Trial name
- NCT05659693
- Testing
- digital literacy education specific to menopause
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Stress
Feasibility and Efficacy of a Digital Training Intervention to Increase Reward Sensitivity- Imager
Development and feasibility test of an Ecological Momentary Intervention (EMI) - Imager, to promote and improve stress resilience, specifically to increase reward sensitivity.
- Trial name
- IMAGER (NCT05623826)
- Testing
- Cognitive- behavioral imagery-based training
- Where
- Switzerland
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Physical Activity - Digital Phenotyping - Activity Tracking
Unveiling the Digital Phenotype of PA Behavior
Observational data from healthy adults aged 65+ will be collected through cross-sectional and longitudinal methods to analyze physical activity patterns, identifying digital phenotypes.
- Trial name
- MIADP (NCT06094374)
- Testing
- observation of physical activity behavior
- Volunteers
- 200 people
- Sponsor
- PXL University College
Colorectal Cancer, Fatigue
UNTIRE: Cancer-related Fatigue With Digital Treatment
This research is being done to find out if using a smartphone app as digital treatment to reduce Cancer Related Fatigue is feasible and easy to use.
- Trial name
- NCT05584540
- Testing
- UNTIRE App
- Where
- United States
- Sponsor
- Dana-Farber Cancer Institute
Substance Use Disorder (SUD)
Correctional Service of Canada Pilot Trial of Digital Substance Use Disorder Interventions (PROCESS)
Problems with substance use are common in prisoners. Since most substances are still illegal in Canada, substance use problems can increase the risk for re-incarceration.
- Trial name
- PROCESS (NCT07342218)
- Testing
- Breaking Free Online (BFO), Computer-Based Training for Cognitive Behavioural Therapy (CBT4CBT)
- Where
- 4 sites in Canada
- Volunteers
- 20 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Cerebral Palsy (CP), Motor Disability
Complex Rehabilitation Technology Enabled Physical Activity for Children With Motor Delays Via Telehealth in Natural Environments
The primary goal of CP-MOVES is to evaluate 1) the preliminary efficacy of a telehealth-delivered, parent coaching intervention in the use of adaptive standers, on physical activity, sleep, and endurance in young children with…
- Conditions
- Cerebral Palsy (CP), Motor Disability, Motor Delay
- Trial name
- CP-MOVES (NCT07252713)
- Testing
- Stander Use
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ohio State University
Device Latency
Substudy of the Accuracy of Ingestible Event Marker (IEM) Detection by the Medical Information Device #1 (MIND1)
The purpose of this study was to determine the accuracy of IEM detection by the MIND1 System by completing a series of Patch applications and IEM ingestions in the clinic.
- Trial name
- OSMITTER (NCT02091882)
- Testing
- Combination product of Aripiprazole + IEM + Sensor + MIND1 Application
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Oral Health
SmartJournal for Improved Oral Care in Nursing Homes
Poor oral health is common in care-dependent older adults, and healthcare professionals report numerous barriers when it comes to provision of oral care for elderly patients.
- Trial name
- NCT05724043
- Testing
- SmartJournal
- Where
- Norway
- Volunteers
- 322 people
- Sponsor
- Oral Health Center of Expertise Rogaland, Norway
Amblyopia, Vision; Low, One Eye (Other Eye Normal)
Next Generation Home Vision Assessment
Comparison of live remote paediatric digital vision testing outcomes versus face to face appointments in orthoptic clinic
- Conditions
- Amblyopia, Vision; Low, One Eye (Other Eye Normal), Pediatric Disorder
- Trial name
- NGHVA (NCT06428435)
- Testing
- Vision Test
- Where
- 4 sites in United Kingdom
- Volunteers
- 206 people
- Sponsor
- NHS Forth Valley
Diabetes Mellitus, Diabetic Retinopathy
Efficacy and Safety of AEYE-DS Software Device for Automated Detection of Diabetic Retinopathy From Digital Fundus Images
AEYE-DS is a software device developed to increase compliance with diabetic retinopathy screening by automatically detecting more-than-mild diabetic retinopathy from digital fundus images using Artificial Intelligence (AI)-based…
- Trial name
- NCT04612868
- Testing
- AEYE Software Device
- Where
- United States
- Volunteers
- 531 people
- Sponsor
- AEYE Health Inc
Pediatric Obesity
Pilot RCT of E4W App in Adolescents
Recommendations for weight management in adolescents with obesity include setting small goals to improve eating behaviours. This frequently includes manually recording food intake over a few days.
- Trial name
- NCT05548868
- Testing
- E4W mobile app, Standard Care
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- The Hospital for Sick Children
Hematologic Malignancy, Stem Cell Transplant
Mosaic Trial for Stem Cell Transplant Recipients
The goal of this clinical trial is to learn if using an intervention website (Mosaic) improves selected patient-reported outcomes in adult blood cancer patients undergoing allogeneic or autologous stem cell transplant, compared…
- Conditions
- Hematologic Malignancy, Stem Cell Transplant, Bone Marrow Transplant, Leukemia
- Trial name
- Mosaic (NCT06960993)
- Testing
- Intervention website, Enhanced Usual Care (Control) Website
- Where
- 3 sites in United States
- Volunteers
- 356 people
- Sponsor
- Northwestern University
Diet Habit
Dietary Assessment Study Via Digital Images
The purpose of this investigation is to validate a passive image-assisted dietary assessment method using images taken by Sony Smarteyeglass and an automatic image analysis software, DietCam, to identify food items and estimate…
- Trial name
- NCT03267004
- Testing
- Dietary Assessment of Meal A using images taken by Sony Smarteyeglass, Dietary Assessment of Meal B using Images taken by Sony Smarteyeglass
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
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