Clinical trials: Digital Tomosynthesis
Breast Neoplasms, Breast Abnormalities
Detection and/or Evaluation of Dense Breast Abnormalities Using Tomosynthesis and Digital Mammography
The purpose of this study is to compare 3D mammography with digital mammography in women with dense breasts for the detection and evaluation of masses and/or breast cancer.
- Trial name
- NCT00722059
- Testing
- Breast Tomosynthesis
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Breast - Female, Dense Breast Parenchyma
Evaluation and Reclassification of ( BI-RADS 3) Breast Lesions in Dense Breast
This prospective study aims to compare combined breast ultrasound (US) and digital mammography (DM) with digital breast tomosynthesis (DBT) in the evaluation and reclassification of BI-RADS 3 (probably benign) breast lesions.
- Conditions
- Breast - Female, Dense Breast Parenchyma, Breast Lesion, Digital Mammography
- Trial name
- NCT07804147
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Breast Cancer
The Effect of Digital Breast Tomosynthesis in Breast Cancer Long-term Survival: a Single Institution Study
To investigate whether digital breast tomosynthesis (DBT) benefits survival improvement.
- Trial name
- NCT05600257
- Testing
- DBT, DM
- Where
- Taiwan
- Volunteers
- 1,517 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Breast Cancer
Test of Digital Breast Tomosynthesis vs. Common Mammography to Detect Breast Cancer for Women Undergoing Breast Biopsy
Comparison of the ability of DBT and FFDM to detect breast cancer.
- Trial name
- NCT00535184
- Volunteers
- 220 people
- Sponsor
- GE Healthcare
Breast Cancer Screening
B.Brilliant Revelation Comparision Study
This is an observational study to evaluate the MAMMOMAT B.brilliant system. All diagnostic decisions are made by the treating radiologist based upon standard of care clinical imaging acquired on FDA approved devices
- Trial name
- NCT07067788
- Testing
- Breast Imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer
Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts
The over-arching goal of the Contrast-Enhanced Spectral Mammography Imaging Screening Trial (CMIST) is to determine if dual-energy contrast-enhanced spectral mammography (CESM) can detect more cancers with fewer false positives…
- Trial name
- CMIST (NCT05625659)
- Testing
- Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 2,032 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Routine Screening Mammography
Acquisition and Clinical Image Evaluation of Fujifilm's High Resolution (HR) Digital Breast Tomosynthesis (DBT) Images.
Acquisition and clinical image evaluation of Fujifilm High Resolution (HR) Digital Breast Tomosynthesis (DBT) images.
- Trial name
- NCT07471750
- Testing
- DBT HR mode image acquisition
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Breast Cancer Screening
Breast Cancer Screening: Digital Breast Tomosynthesis Versus Digital 2D Mammography
This study is a randomized, multicenter, multivendor, controlled, diagnostic superiority trial to compare digital breast tomosynthesis plus synthesized 2D mammograms (DBT+s2D) versus standard 2D full-field digital mammography…
- Trial name
- TOSYMA (NCT03377036)
- Testing
- DBT+s2D, 2D-FFDM
- Where
- 21 sites in Germany
- Volunteers
- 99,689 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Architectural Distortions, Breast Tomosynthesis
Comparison of Conspicuity of Masses and Architectural Distortions Between Wide- and Narrow-angle Digital Breast Tomosynthesis Systems
To compare narrow-angle digital breast tomosynthesis (DBT) and wide-angle DBT.
- Trial name
- NCT06373354
- Testing
- Digital Breast Tomosynthesis (DBT)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- M.D. Anderson Cancer Center
Female Breast Cancer
Tomosymthesis for Breast Mass Lesion Characterization
To Estimate diagnostic value of tomo synthesis for breast mass lesions characterization ( shape, margin, and density, detail of mass margins, Differences in mass density , Tumor measurement,.)
- Trial name
- DBT (NCT04863833)
- Volunteers
- 30 people
- Sponsor
- Asmaa Abdelmonem Ahmed
Breast Cancer
Tomosynthesis Mammographic Imaging Screening Trial
A randomized screening trial to compare the diagnostic accuracy of screening for breast cancer with three-dimensional digital breast tomosynthesis (DBT) plus two-dimensional full-field digital mammography (FFDM) versus FFDM alone.
- Trial name
- TMISTLead-in (NCT02616432)
- Testing
- Tomosynthesis
- Where
- 4 sites in Canada
- Volunteers
- 3,065 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
Comparison of the Philips MicroDose Tomosynthesis System to 2D Digital Mammography
The primary objective of this study is to compare the safety and clinical performance of the Philips MicroDose Tomosynthesis system images and images from FFDM systems.
- Trial name
- NCT02615509
- Testing
- Imaging on experimental tomo device
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Philips Digital Mammography Sweden AB
Breast Carcinoma
Molecular Breast Imaging and Digital Breast Tomosynthesis in Screening Patients With Dense Breast Tissue
This study compares molecular breast imaging (MBI) and digital breast tomosynthesis (DBT) in screening patients with dense breast tissue. Breast imaging may help doctors find breast cancer sooner, when it may be easier to treat.
- Trial name
- NCT03220893
- Testing
- Digital Breast Tomosynthesis (DBT), Scintimammography
- Where
- 5 sites in United States
- Volunteers
- 3,023 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer
Assessment of Periodic Screening of Women With Denser Breast Using WBUS and DBT
The purpose of this study is to evaluate the role of technologist-performed whole breast ultrasound for detecting breast cancer in the screening population of women with dense breasts.
- Trial name
- DBTUST (NCT02643966)
- Testing
- Whole breast ultrasound
- Where
- 2 sites in United States
- Volunteers
- 6,266 people, healthy volunteers welcome
- Sponsor
- Wendie Berg
Recall Rate, Cancer Detection Rate
Tomosynthesis in the Oslo Breast Cancer Screening Program
The Digital Breast Tomosynthesis (DBT) in the Oslo Mammography Screening Program will include women aged 50 to 69 years invited to the population-based mammography-screening program.
- Conditions
- Recall Rate, Cancer Detection Rate, False Positive Rate, Positive Predictive Value
- Trial name
- DBT (NCT01248546)
- Testing
- Digital breast tomosynthesis
- Where
- Norway
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Breast Cancer, Breast Neoplasms
Biennial CEM in Women With a Personal History of Breast Cancer
This is a prospective clinical trial that will examine if biennial contrast-enhanced mammography added to annual 3D mammography (tomosynthesis) substantially improves breast cancer detection with minimal increase in…
- Conditions
- Breast Cancer, Breast Neoplasms, Breast Cancer Female, Neoplasms
- Trial name
- NCT06105749
- Testing
- contrast-enhanced mammography
- Where
- 6 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Wendie Berg
Breast Cancer Screening
Project 1: Self-Triage by 2D Full-field Digital Mammography or Synthetic Images
One method of breast cancer screening involves radiologists reading digital tomosynthesis (DBT) images. DBT consists of a 3D stack of x-ray "slices" through the breast.
- Trial name
- NCT05960188
- Testing
- AI Opinion
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer Female, Breast Cancer
Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania
This is a prospective clinical trial that will examine if contrast-enhanced mammography substantially improves breast cancer detection compared to mammography with tomosynthesis, with minimal increase in false-positives, in women…
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Neoplasms, Neoplasms
- Trial name
- TOCEM (NCT04085510)
- Testing
- Contrast-enhanced mammogram
- Where
- 3 sites in United States
- Volunteers
- 1,647 people, healthy volunteers welcome
- Sponsor
- Wendie Berg
Breast Cancer Screening
Breast Cancer Screening for Underserved Women: Comparing Outcomes and Lowering Recall Rates With 3D- vs. 2D-mammography
Three-dimensional (3D) + two-dimensional (2D)- mammography may have particular value for minority, rural, and underserved women in New Mexico by decreasing recall rates and improving diagnostic sensitivity, thus alleviating some…
- Trial name
- NCT03979729
- Testing
- Routine Screening Mammogram (3D + 2D), Routine Screening Mammogram (2D), No Screening Mammogram
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- New Mexico Cancer Research Alliance
Digital Breast Tomosynthesis
The Added Value of DBT Over Mammography in Local Tumor Staging in Patients With BIRADS 4 or 5 Lesions
Compare the diagnostic accuracy of tomosynthesis with 2D mammography in cases with suspected BI-RADS 4 or 5 to determine its potential benefit for staging
- Trial name
- NCT06854887
- Testing
- digital breast tomosynthesis and mammography
- Volunteers
- 64 people
- Sponsor
- Assiut University