Clinical trials: Digital Well-being
Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor
Transthyretin amyloid cardiomyopathy (ATTR-CM) is a heart condition caused by a protein called transthyretin (TTR) building up as amyloid in the heart muscle.
- Trial name
- ACO-MONITOR (NCT07557147)
- Testing
- Luscii
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Bayer
Covid19
Western Kenya Integrated COVID-19 Response
To respond to the COVID-19 pandemic, investigators will be deploying community health workers, equipped with mobile technology, and accompanied by youth to visit households door to door to screen for symptoms of COVID-19…
- Trial name
- NCT04501458
- Testing
- Training of youth, community health assistants and community health workers., Training clinicians in basic critical care and the management of severe COVID-19 cases
- Where
- Kenya
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Surgical Systems Research Group
Breast Cancer Stage IV
Trastuzumab Deruxtecan in First-Line HER2-Positive Metastatic Breast Cancer With Proactive Toxicity Management
This is an open-label, single arm, non-randomized, multicenter, phase 2 study assessing the efficacy and safety of T-DXd as first-line treatment in HER2-positive advanced/metastatic BC patients (N=300).
- Trial name
- TOP-REAL (NCT07371585)
- Testing
- Digital Health Tools, T-DXd, Pertuzumab
- Where
- 27 sites in France, Germany and 1 more
- Volunteers
- 300 people
- Sponsor
- SOLTI Breast Cancer Research Group
Digital Game Addiction, Sleep Deprivation
School-Based Self-Regulation Intervention for Digital Game Addiction and Sleep Deprivation
This study evaluates the effectiveness of a school-based self-regulation intervention designed to reduce digital game addiction and sleep deprivation among adolescents aged 10-14 years.
- Conditions
- Digital Game Addiction, Sleep Deprivation, Problematic Digital Gaming, Adolescent Behavioral Health
- Trial name
- SRDGA (NCT07423689)
- Testing
- School-Based Self-Regulation Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Turkan Akyol Guner
Mental Distress, Mental Resilience
Digital Care Programs for Mental Health
The purpose of this study is to create a research repository, composed of data collected over the course of digital care programs for mental health distress delivered by Sword Mind to individuals.
- Trial name
- NCT07183085
- Testing
- Intervention
- Where
- United States
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Sword Health, SA
Mental Health Care, Mental Disorders
Using Responsible Artificial Intelligence (AI) to Predict Online Therapy Outcome and Engagement
This study is to develop AI-based models for the personalised prediction of treatment engagement and treatment outcomes in patients engaging in digital psychotherapy.
- Trial name
- NCT05758285
- Testing
- AI-Based Prediction of Treatment Engagement and Outcomes
- Where
- Switzerland
- Volunteers
- 6,671 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Head and Neck Vascular Stenosis
Effectiveness of Digital Health Management on Patients With Head and Neck Vascular Stenosis
The purpose of this study is to evaluate the effectiveness of digital health management for intervention on Chinese population with head and neck vascular stenosis.
- Trial name
- NCT05798013
- Testing
- Digital health management
- Where
- China
- Volunteers
- 102,072 people
- Sponsor
- Yi Yang
Level of Digital Game Addiction, Level of Cyberbullying
Digital Game Addiction and Cyberbullying in Adolescents
With the widespread use of technology and internet, digital game addiction and cyberbullying behaviors have increased among adolescents. Effective interventions are needed to prevent these behaviors.
- Trial name
- NCT06241989
- Testing
- health education supported by motivational interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Fetal Alcohol Spectrum Disorders, Pregnancy
CARRII Native Intervention Optimization Trial
The purpose of this study is to identify the best combination of new intervention components to use with CARRII, the first automated online intervention for alcohol-exposed pregnancies (AEP).
- Conditions
- Fetal Alcohol Spectrum Disorders, Pregnancy, Alcohol-Related Disorders, Drinking, Alcohol
- Trial name
- NCT07547696
- Testing
- CARRII Native Cores
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Behavior, Health, Diet Modification
Testing the Feasibility of the DASH Cloud Intervention Using Amazon Alexa
The DASH diet is a proven behavioral strategy to reduce blood pressure, however, national adherence rates are poor. Using digital health tools may help to improve adoption of the DASH diet.
- Trial name
- NCT03455946
- Testing
- DASH cloud with Alexa
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Duke University
Pregnancy Related, Weight Gain
HealthyPregnancy - Digital Support for Pregnant Women with a BMI At 25 or Above (BMI≥25)
The study aims to examine the effectiveness of a digital care guide offering support and information on diet, physical exercise and mental well-being on pregnancy weight gain among pregnant women with a BMI at 25 or above in a…
- Trial name
- NCT06734910
- Testing
- HealthyPregnancy
- Where
- 2 sites in Denmark
- Volunteers
- 450 people
- Sponsor
- Center for Clinical Research and Prevention
Cognitive Wellness, Healthy Aging
MEVA Cognitive Wellness Platform Study for Adults
The goal of this observational study is to evaluate the reliability, usability, and feasibility of the MEVA Cognitive Wellness Platform in community-dwelling adults aged 55 to 75.
- Conditions
- Cognitive Wellness, Healthy Aging, Age-Related Cognitive Change, Aging
- Trial name
- MEVA (NCT07595250)
- Testing
- MEVA Cognitive Wellness Platform
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mentage LLC
Chronic Insomnia
Digital Management of Sleep Health
The goal of this clinical trial is to explore whether cognitive behavioral intervention for insomnia(CBT-I) realized through audio, video, and articles on smartphone apps("ForSleep" developed by the investigators) can improve the…
- Trial name
- NCT06481423
- Testing
- dCBT-I, Relaxing music
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Jia Xiu
Vaccination
Optimizing Weblinks Used in Digital Vaccination Invitations to Raise Trust and Booking Intention: Online Experiment 3
This study investigates how the design of weblinks in digital vaccination invitation emails influences recipient trust and their willingness to book an appointment.
- Trial name
- NCT07538349
- Testing
- Improvement to the weblink included in the vaccination email invitation, Concealing the weblink included in vaccination email invitation
- Where
- United Kingdom
- Volunteers
- 4,014 people, healthy volunteers welcome
- Sponsor
- University of Essex
Denture, Complete
Conventional Versus Neutral-Zone CAD/CAM Dentures Restoring Mandibular Resorbed Ridges
The study is a within-subject randomized clinical trial that will compare and evaluate patients' satisfaction and digitally analyze denture space Confines. Group I: CAD/CAM.
- Trial name
- CAD/CAM (NCT05895292)
- Testing
- CAD/CAM Milled Methacrylate Complete Removable Dentures based on bone-support concept., CAD/CAM Milled Methacrylate Complete Removable Dentures based on neutral zone concept.
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
Internet-Based Cognitive Behavioral Therapy With Treatment as Usual for Generalized Anxiety Disorder and Major Depressive Disorder in Taiwan (ICBT-TW)
This study aims to evaluate the effectiveness of internet-based cognitive behavioral therapy (ICBT) combined with treatment as usual (TAU) for adults diagnosed with generalized anxiety disorder (GAD) or major depressive disorder…
- Trial name
- ICBT-TW (NCT07177365)
- Testing
- Internet-Based Cognitive Behavioral Therapy (ICBT), Treatment as Usual (TAU) Only
- Volunteers
- 120 people
- Sponsor
- National Health Research Institutes, Taiwan
Frail Elderly Syndrome, Older Adults
A Digital Home-Based Physiotherapy Program for Active Aging
This clinical trial will aim to understand the effects of the TRAK-SILVER digital platform on pre-frail and older adults living at home, assessing its impact on physical activity level, emotional variables, and overall quality of…
- Trial name
- TRAK-SILVER (NCT06381336)
- Testing
- TRAK-SILVER platform
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Trak Health Solutions S.L.
Hip Fractures, Frailty
AI-Supported Physiotherapy After Hip Fracture in Frail Older Adults
Purpose Hip fractures in older adults often cause a serious loss of strength and independence. Physical therapy helps people recover, but patients do not always exercise consistently or correctly.
- Trial name
- Fisio-ACTIVA (NCT07857707)
- Testing
- Conventional hospital physiotherapy, Automated motivational support and movement-capture system
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Postnatal Depression, Mother-Infant Interaction
A Virtual Support Intervention for Postnatal Well-being
Postnatal depression (PND) and anxiety are significant public health concerns affecting a substantial proportion of new mothers worldwide.
- Trial name
- NCT06557200
- Testing
- Digital Infant- parents support
- Where
- Pakistan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Attention Deficit Hyperactivity Disorder
dHealth Solution for Improving Parent Adherence to Behavioral Treatment for ADHD
This study aims to develop, refine and preliminarily test a novel and scalable digital health solution designed to address parent adherence barriers in daily life contexts and increase parent's sustained use of evidence-based…
- Trial name
- dHealth (NCT04025814)
- Testing
- CaregiverAssist, Behavioral Parent Training (CLS Parent Group)
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
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