Clinical trials: Diplegia, Spastic
Cerebral Palsy (CP)
Effects of Circuit Training and Task Oriented Training on Balance and Quality of Life in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is a group of permanent disorders affecting movement and posture, caused by non-progressive disturbances in the developing fetal or infant brain.
- Trial name
- NCT07799064
- Testing
- Group A Circuit Training, Group B Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 25 people
- Sponsor
- Ibadat International University, Islamabad
Spastic Diplegic Cerebral Palsy
Sensory Walkway and Gait in Children With Diplegic Cerebral Palsy
This study aims to evaluate the effect of sensory walkway training on gait performance in children with spastic diplegic cerebral palsy.
- Trial name
- SWGCP (NCT07595744)
- Testing
- Conventional Physical Therapy Program, Sensory Walkway Training
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Cerebral Palsy
Effect of Antigravity Shoes on Improving the Quality of Gait in Children With Spastic Diplegia
Improving the quality of gait in the diplegic children is a major concern in the rehabilitation program. Thirty children with spastic diplegia were distributed equally into 2 groups, group A (control) and group B (study).
- Trial name
- NCT04117282
- Testing
- gait training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy, Gait Disorders, Neurologic
Precision Gait Retraining for Children With Cerebral Palsy
This project will develop the first sensor-based mobile Pelvic Assist Device (mPAD) that can deliver precise, adaptable, pelvic control to restore natural coordination of upper- and lower-limb movements during gait in children…
- Trial name
- NCT04717323
- Testing
- mPAD (or TPAD) Pelvic Assist Device, No Intervention
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Altec Inc.
Cerebral Palsy Spastic Diplegia
Investigation of the Effects of Diaphragm Exercises in Children With Cerebral Palsy
The aim of this study is to examine the effects of diaphragmatic myofascial relaxation exercise and diaphragmatic breathing exercises added to the conventional physiotherapy and rehabilitation program in children with diplegic…
- Trial name
- NCT05559346
- Testing
- Diaphragmatic exercises, conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Uskudar University
Gait, Spastic Diplegia
Efficacy of Combination Taping Technique vs Ankle Foot Orthosis on Improving Gait Parameters in Cerebral Palsy
Gait in children with spastic CP is often characterized by abnormal gait kinematics as knee flexion and equines foot which associated with such gait deviations, an elevated walking energy cost is often observed which may…
- Trial name
- NCT04839939
- Testing
- Conventional physical therapy, Ankle Foot Orthosis, Combination Taping
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- Batterjee Medical College
Children With Spastic Diplegia, Between the Ages of 2 to 10 Years, Gross Motor Function Classification System (GMFCS) Level I,II and III
Effects of Mirror Neurons Stimulation on Motor Skill Rehabilitation in Children With Cerebral Palsy
This study aimed to develop Video Compact Disc (VCD) program that applying the concept of imitative learning with mirror neurons stimulation on standard rehabilitation technique in children with cerebral palsy.
- Trial name
- NCT01267929
- Testing
- The mirror neurons stimulation based VCD program, The conventional physical therapy
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Thammasat University
Cerebral Palsy, Spastic Diplegia Cerebral Palsy
The Effect of Action Observation Therapy on Spasticity, Motor Function, and Balance in Children With Cerebral Palsy
In our randomized controlled study, which aims to investigate the contribution of Action Observation Therapy to rehabilitation by examining the effect of Action Observation Therapy on spasticity, gross motor function, balance and…
- Conditions
- Cerebral Palsy, Spastic Diplegia Cerebral Palsy, Hemiplegic Cerebral Palsy
- Trial name
- AOT-CP (NCT07247331)
- Testing
- action observation therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Suleyman Demirel University
Gait, Spastic
Effect of Weight on Hip Excursion During Gait
Background: Children with diplegia had considerably larger hip and knee excursion during gait cycle than did normal developing children.
- Trial name
- NCT05579535
- Testing
- gait training exercises
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Cerebral Palsy Spastic Diplegia
Virtual Reality Training With Sensory Integration On The Gross Motor Functions Of Lower Limb
The objectives of this study are To determine the effect of virtual reality on balance and gross motor functions of the lower limb in spastic diplegic cerebral palsy.
- Trial name
- NCT04467385
- Testing
- VR training + Sensory Integration therapy + conventional therapy, VR training + conventional therapy
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Spastic Diplegia Cerebral Palsy
Dual-Task Training in Children With Spastic Diplegic Cerebral Palsy
This randomized controlled trial aims to investigate the effect of dual-task oriented training on functional performance in children with spastic diplegic cerebral palsy. Participants will be randomly assigned to two groups.
- Trial name
- NCT07870135
- Testing
- Dual-Task oriented, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Raneem Ahmad Mohammad Ashshi
Spastic Diplegia, Periventricular Leukomalacia
Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia
This is a randomized controlled trial, comparing 3 months of intensive leg exercise to standard physiotherapy care for the improvement of gross motor function in young children with spastic diplegia.
- Trial name
- NCT03672877
- Testing
- Intensive exercise
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Diplegic Cerebral Palsy
"Immediate Effect of DAFO on Gross Motor Function and Balance in Diplegic Cerebral Palsy
" Study will investigate the immediate effect of DAFO usage on balance and gross motor functions in individuals with spastic diplegic cerebral palsy.
- Trial name
- NCT06343688
- Testing
- "Assessment of Balance and Lower Extremity Gross Motor Function with and without DAFO"
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
Healthy Little Eyes
The purpose of this research study is to gather more information on how eye injury is related to a baby's future development and see if eye function and brain test results can be used, along with current measures, to better…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Encephalopathy
- Trial name
- NCT05971446
- Testing
- Visual Evoked Potential (VEP), Electroretinogram (ERG)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Thrombotic Thrombocytopenic Purpura (TTP)
A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)
This is a study of TAK-755 in adults with immune-mediated thrombotic thrombocytopenic purpura (iTTP). The main aim of this study is to determine the percentage of participants with a clinical (Part 1) or platelet (Part 2)…
- Trial name
- NCT05714969
- Testing
- TAK-755
- Where
- 22 sites in United States, Austria and 4 more
- Volunteers
- 29 people
- Sponsor
- Takeda
Mothers of Children With Colostomy, A Multi-component Educational Program
Effectiveness of a Digital Educational Booklet on Mothers' Colostomy Care Knowledge and Practices
This study aimed to evaluate the effectiveness of a digital education and simulation-supported training intervention on mothers' knowledge and practices regarding colostomy care for their children.
- Conditions
- Mothers of Children With Colostomy, A Multi-component Educational Program, Digital Booklet, WhatsApp
- Trial name
- NCT07662707
- Testing
- digital education and simulation-supported training intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- King Saud Bin Abdulaziz University for Health Sciences
Tobacco Use, Oxidative Stress
Little Cigar Oxidants
Determine the effects of little cigars on human exposure to tobacco smoke oxidants. In a balanced randomized cross-over study design in cigarette smokers, subjects will be assigned to 3 exposure groups.
- Trial name
- NCT06310187
- Testing
- High Oxidant Little Cigar, Low Oxidant Little Cigar, Usual Cigarette
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Milton S. Hershey Medical Center
Cerebral Palsy Spastic Diplegia
Oculomotor Training in Spastic Diplegia: Effects on Postural Stability and Motor Proficiency
This randomized clinical trial investigates the effect of oculomotor training on postural stability and motor proficiency in children with spastic diplegia.
- Trial name
- NCT07731074
- Testing
- Oculomotor Training, Conventional Physiotherapy
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Dynamic Surface Exercise Training and Static Surface Exercise Training in Cerebral Palsy Children
This randomized clinical trial aims to compare the effects of Dynamic Surface Exercise Training (DSET) and Static Surface Exercise Training (SSET) on balance and gross motor function in children with spastic diplegic cerebral…
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Gross Motor Functions, Balance
- Trial name
- NCT07129785
- Testing
- Dynamic Surface Exercise Training (DSET), Static Surface Exercise Training (SSET)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Lahore
Cerebral Palsy, Spastic Diplegia Cerebral Palsy
FES to Improve Gait in CP
The goal of this proposal is to mitigate the typical decline in walking function experienced by children with cerebral palsy (CP) via a Functional Electrical Stimulation (FES)-assisted treadmill training intervention.
- Conditions
- Cerebral Palsy, Spastic Diplegia Cerebral Palsy, Gait
- Trial name
- CP FES Walking (NCT04591288)
- Testing
- Functional Electrical Stimulation protocol, Treadmill only protocol
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Shriners Hospitals for Children