Clinical trials: Diplegia
Spastic Diplegia
Early Intensive Exercise to Improve Walking in Children With Spastic Diplegia
This is a randomized controlled trial comparing 3 months of intensive leg exercise to standard physiotherapy care for the improvement of motor function in the legs in young children with spastic diplegia.
- Trial name
- NCT03166293
- Testing
- Intensive leg training with a physical therapist
- Where
- 2 sites in Canada
- Volunteers
- 4 people
- Sponsor
- University of Alberta
CP (Cerebral Palsy), Diplegia
Static and Dynamic Postural Stability in Cerebral Palsy Children
Cerebral palsy (CP) concerns 2 children out of 1000 in the general population (SCPE 2002). It is the main cause of postural and motor deficits in children.
- Conditions
- CP (Cerebral Palsy), Diplegia, Hemiplegia, Postural; Defect
- Trial name
- Dual-Task (NCT01799304)
- Testing
- no distractor control group, visual and sound attentional distractors, sound attentional distractor alone
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Grenoble
Cerebral Palsy
Motion Analysis of Sit-to-Stand Movements in Children With Spastic Diplegia
The purpose of this study is to compare movement variations before and after the loaded training, with kinematics, kinetics, and electromyography, in children with spastic diplegia and to further discuss mechanisms of the loaded…
- Trial name
- NCT00314301
- Testing
- loaded sit-to-stand training
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Far Eastern Memorial Hospital
Spastic Diplegic Cerebral Palsy
Effect of Virtual Reality Mediated Gamified Rehabilitation in Children With Spastic Diplegic Cerebral Palsy
This randomized controlled trial aimed to evaluate the effectiveness of a Virtual Reality (VR)-mediated gamified rehabilitation program compared with conventional physical therapy in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07747961
- Testing
- Experimental Group, Control
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Ibadat International University, Islamabad
Cerebral Palsy, Spastic Diplegia
Evaluation of Brain MRI Changes in Cerebral Palsy Patients
Cerebral palsy (CP) is a neurodevelopmental syndrome characterized by sensorimotor impairment that arises during early childhood defined as a static insult to the developing brain.
- Conditions
- Cerebral Palsy, Spastic Diplegia, Spastic Quadriplegia, Spastic Hemiplegia
- Trial name
- NCT07433647
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Columbia University
Spastic Diplegia Cerebral Palsy
Post Facilitation Stretch, Post Isometric Relaxation and Myofascial Release in Spastic Cerebral Palsy.
The purpose of the study is to compare the effect of Post Facilitation Stretch, Post Isometric Relaxation and Myofascial Release on Lower Limb Spasticity in Spastic Cerebral Palsy.
- Trial name
- NCT06686719
- Testing
- Post Facilitation, Post Isometric Relaxation, Myofascial Release
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Cerebral Palsy, Spastic Diplegia
Walking Inclined Plane
The adaptations in kinematics and muscle activity, investigated by 3D gait analysis and dynamic electromyography recordings, will be studied in children with bilateral spastic cerebral palsy during level walking, and before and…
- Trial name
- NCT02988557
- Testing
- walking on a treadmill with a sloped surface, treadmill
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Spastic Diplegia Cerebral Palsy
Effect of Spring Gravity Bar on Gait Pattern in Children With Spastic Diplegia
The purpose of the study is to determine the effect of spring gravity bar on gait pattern in children with spastic diplegia
- Trial name
- NCT04628247
- Testing
- Spring gravity bar
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Cerebral Palsy, Diplegia, Spastic
Validity of the Kinematic Classification of Gait in Diplegic Children With Cerebral Palsy (CP)
In recent years Ferrari et al. proposed a new classification of gait in diplegic children with spastic diplegia that describes four different patterns of gait by analyzing the strategies that each children adopts to need his/her…
- Trial name
- NCT01158833
- Testing
- classification of gait in diplegic children with CP
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Modena and Reggio Emilia
Gait Disorders in Children, Cerebral Palsy Spastic Diplegia
Comparison of Walking Parameters Between Idiopathic Toe Walking and Independent Walking Diparetic Cerebral Palsy
The aim of the observational study is to compare static, kinematic and kinetic parameters with normal gait parameters in cases with Idiopathic toe walking (ITW) and Diparetic Cerebral Palsy (DCP) who have Gross Motor Function…
- Trial name
- NCT06142721
- Testing
- 3D Gait Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Biruni University
Hyperekplexia, CTNNB1 Gene Mutation
Hyperekplexia in Patients With CTNNB1 Mutation
A few years ago, a new genetic disorder (OMIM # 615075) has been associated with loss-of-function variations in the CTNNB1 gene.
- Trial name
- CTNNB1 (NCT05168969)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spastic Diplegia Cerebral Palsy, Spastic Hemiplegia
Spinal Mobility in Children With Cerebral Palsy: NDT-Bobath and Exergaming
The purpose of this study is to evaluate changes in spinal mobility in the cervical, thoracic, and lumbar regions in children with cerebral palsy aged 10-15 years.
- Trial name
- NCT07421505
- Testing
- NDT-Bobath Therapy, Sitting Exergaming, Standing Exergaming
- Where
- 2 sites in Poland
- Volunteers
- 42 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Cerebral Palsy, Acquired Brain Injury
Virtual Reality and Active Video Games to Improve Balance in Children With Brain Injury
The purpose of this pilot feasibility study is to assess the feasibility of using the Playstation Xbox 360 and Rutgers V-step via a Kinect Sensor with active video game software as a part of a physical therapy intervention to…
- Trial name
- NCT03386968
- Testing
- Active video gaming, Usual care physical therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Blythedale Children's Hospital
Cerebral Palsy (CP)
TENS With Proprioceptive-Visual Training on Gait Parameters in CP
This study aimed to evaluate the effect of TENS with proprioceptive - visual training on gait parameters in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07338994
- Testing
- TENS, 1. Tekscan Walkway system
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Spastic Diplegic Cerebral Palsy
A New Multimodal Treatment Approach for Children With Spastic Diplegic Cerebral Palsy
Combining the advantages of both Neuromuscular electrical stimulation and lower limb serial casting to a selected physical therapy program in children with spastic diplegic cerebral palsy to overcome the adverse effects during…
- Trial name
- NCT05504798
- Testing
- Selected physical therapy program, Interrupted serial casting, Neuromuscular electrical stimulation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cerebral Palsy
Moderate Versus High-intensity Interval Training in Children With Diplegia.
The aim is to compare the effects of moderate-intensity training and high-intensity interval training on gait, energy expenditure, and functional mobility in children with spastic diplegia.
- Trial name
- NCT07289373
- Testing
- Moderate intensity training, High intensity interval training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Spastic Diplegic Cerebral Palsy
Study of a Stationary Cycling Intervention for Children With Spastic Diplegic Cerebral Palsy
The study is about the effect of an exercise program using stationary bicycling for children with the spastic diplegic form of cerebral palsy.
- Trial name
- PEDALS (NCT00401154)
- Testing
- Stationary Cycling
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Southern California
Spastic Diplegia
Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy
The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.
- Trial name
- NCT02535936
- Testing
- 3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cerebral Palsy, Gait Disorders
The Effects of Exoskeletal Robot-Assisted Gait Training on Children With Cerebral Palsy: A Pilot Study
Cerebral Palsy (CP) is a complex neurodevelopmental disorder caused by early brain injury, leading to motor impairments such as muscle weakness, stiffness, and gait instability, which impact daily functioning.
- Conditions
- Cerebral Palsy, Gait Disorders, Gait Disorders in Children, Gait Disorders, Neurologic
- Trial name
- NCT05759182
- Testing
- Powered Exoskeleton Gait Training
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Functional Electrical Stimulation, Cerebral Palsy
Functional Electrical Stimulation With Core Stabilization Exercises in Children With Spastic Diplegia
This study was done to: investigate the combined effect of functional electrical stimulation with core stabilization exercises on pelvic tilting in children with spastic diplegia.
- Conditions
- Functional Electrical Stimulation, Cerebral Palsy, Core Stability
- Trial name
- NCT07110025
- Testing
- designed physical therapy program, core stabilization exercise with neuromuscular electrical stimulation
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University