Clinical trials: Diplegic Cerebral Palsy With Spasticity
Cerebral Palsy
Sensory Integration Therapy and Cerebral Palsy
This intervention study was planned to investigate the effects of Sensory Integration Therapy that added to the conventional therapy program on spasticity, balance, motor function and functional independency levels of children…
- Trial name
- NCT05966428
- Testing
- Conventional Exercises, Sensory Integration Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Cerebral Palsy, Upper Extremity Dysfunction
The Effect of Upper Extremity Strengthening on Functionality, Muscle Strength and Trunk in Children With Cerebral Palsy
Cerebral Palsy (CP) is an activity limitation, movement and posture deficiencies in early stage of life. In 80% of these children, upper extremity (UE) dysfunctions are observed, which leads to loss of quality of life, resulting…
- Conditions
- Cerebral Palsy, Upper Extremity Dysfunction, Upper Extremity Functions, Muscle Strength
- Trial name
- NCT05115695
- Testing
- traditional physiotherapy approach, muscle strengthening exercise/Proprioceptive Neuromuscular Facilitation (PNF)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic
Impact of rTMS Combined With Neurorehabilitation on Lower Extremity Motor Function and Spasticity in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is widely recognized as the most prevalent cause of lifelong physical disability emerging in childhood across most global populations.
- Conditions
- Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic, Transcranial Magnetic Stimilation, Cerebral Palsy (CP)
- Trial name
- NCT07488429
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara City Hospital Bilkent
Cerebral Palsy
Task Oriented Activities Based on NDT Therapy Principles
Cerebral palsy (CP) is one of the primary causes of disability effecting majority of pediatric population. Cerebral Palsy is considered a neurological disorder caused by a non-progressive brain injury or malformation that occurs…
- Trial name
- NCT05903729
- Testing
- Neurodevelopmental therapy treatment, conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Spastic Diplegic Cerebral Palsy
Effects of Vestibular Stimulation in Addition to Conventional Physiotherapy in Improving Gross Motor Function and Mobility in Children With Spastic Diplegic Cerebral Palsy
This was a RCT to determine and compare the effects of vestibular stimulation in addition to conventional physical therapy on gross motor function and mobility in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07712315
- Testing
- Experimental Group A received Vestibular Stimulation along with Conventional therapy., Control Group B received Conventional physiotherapy alone.
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Ibadat International University, Islamabad
Cerebral Palsy Spastic Diplegia
Comparative Effects of Play-Based Therapy and NDT in Diplegic CP
To compare the efficacy of play-based therapy versus NDT in improving fine motor skills in children with Spastic Diplegic Cerebral Palsy.
- Trial name
- NCT07534228
- Testing
- Group B Play-Based Therapy, Group A NDT
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Cerebral Palsy, Spastic, Diplegic
Stretching and Strength Training for Improved Gait Function in Children With Spastic Cerebral Palsy
The purpose of this randomized and controlled intervention study is to explore the effect of a physiotherapy intervention targeting contract and spastic hamstring muscles in children having bilateral spastic cerebral palsy (CP)…
- Trial name
- NCT02917330
- Testing
- Stretching and progressive strength training
- Where
- Norway
- Volunteers
- 34 people
- Sponsor
- Oslo University Hospital
Spastic Diplegic Cerebral Palsy
Effect of Virtual Reality Mediated Gamified Rehabilitation in Children With Spastic Diplegic Cerebral Palsy
This randomized controlled trial aimed to evaluate the effectiveness of a Virtual Reality (VR)-mediated gamified rehabilitation program compared with conventional physical therapy in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07747961
- Testing
- Experimental Group, Control
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Ibadat International University, Islamabad
Spastic Diplegic Cerebral Palsy
Effects of Transcranial Direct Current Stimulation Combined With Virtual Reality on Balance and Executive Functions in Children With Spastic Diplegic Cerebral Palsy
Children with spastic diplegic cerebral palsy commonly experience difficulties with balance and may also have challenges involving attention, working memory, cognitive flexibility, and inhibitory control.
- Trial name
- NCT07829770
- Testing
- Active Transcranial Direct Current Stimulation, Virtual Reality Rehabilitation, Conventional Physical Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Cerebral Palsy Spastic Diplegia
Gait Improvement After Increased Frequency of Robot-assisted Gait Training in Cerebral Palsy Children
Robot-assisted gait training (RAGT) can provide a longer training duration with a higher repetition of stepping while maintaining a stable pattern of movement. However, the existing evidence of its effectiveness is not clear.
- Trial name
- NCT05412485
- Testing
- Robotic assisted gait training
- Where
- United Arab Emirates
- Volunteers
- 20 people
- Sponsor
- University of Sharjah
Spastic Diplegic Cerebral Palsy
Sensory Walkway and Gait in Children With Diplegic Cerebral Palsy
This study aims to evaluate the effect of sensory walkway training on gait performance in children with spastic diplegic cerebral palsy.
- Trial name
- SWGCP (NCT07595744)
- Testing
- Conventional Physical Therapy Program, Sensory Walkway Training
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Cerebral Palsy
Effects Of Bobath Exercises Combined With Gasotransmitter On Spastic Diplegic CP
This study examines the effects of combining Bo bath neurodevelopmental exercises with gasotransmitter in children with spastic diplegic cerebral palsy, a condition marked by muscle stiffness and coordination challenges in the…
- Trial name
- NCT06739538
- Testing
- Bobath exercises, Gasotransmitters
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- Superior University
Cerebral Palsy, Gait, Spastic
Validity and Reliability of the the Timed 360° Turn Test
Cerebral Palsy (CP) is a non-progressive neurodevelopmental disorder that starts in the early stages of life, causes activity limitation, and consists of movement and posture deficiencies.
- Conditions
- Cerebral Palsy, Gait, Spastic, Gait Disorders in Children, Diplegic Cerebral Palsy
- Trial name
- cp (NCT05213039)
- Testing
- assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Spastic Diplegia Cerebral Palsy, Quality of Lifte
Additional Effects of Cuevas Medek Exercises Along With Conventional Physical Therapy on Gross Motor Proficiency and Quality of Life, in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is a prevalent pediatric neurological disorder hindering movement and posture development due to non-progressive disruptions in brain development.
- Conditions
- Spastic Diplegia Cerebral Palsy, Quality of Lifte, Motor Function
- Trial name
- NCT06966609
- Testing
- Control Group, Experimental Group
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Foundation University Islamabad
Cerebral Palsy (CP)
TENS With Proprioceptive-Visual Training on Gait Parameters in CP
This study aimed to evaluate the effect of TENS with proprioceptive - visual training on gait parameters in children with spastic diplegic cerebral palsy.
- Trial name
- NCT07338994
- Testing
- TENS, 1. Tekscan Walkway system
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cerebral Palsy Spastic Diplegia
FES Assisted Cycling in Children With CP
This project proposes to assess if Functional Electrical Stimulation (FES) assisted cycling can improve the cycling ability, muscle strength, cardiovascular health, quality of life, self perception and functional mobility of…
- Trial name
- CP FES Cycling (NCT04688424)
- Testing
- FES, Cycling
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy
Effects of Routine Physical Therapy With and Without Neurodevelopmental Technique on GMF, Spasticity and HRQOL in Diplegic CP
The aim of this study is to investigate the effects of routine physical therapy with and without neurodevelopmental technique on gross motor function, spasticity and health related quality of life in diplegic cerebral palsy.
- Trial name
- NCT06444230
- Testing
- Routine Physical therapy with Neurodevelopmental technique, Routine Physical therapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Cerebral Palsy, Cerebral Palsy, Spastic
Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy
Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations.
- Trial name
- HABIT-ILE (NCT07253857)
- Testing
- GROUP -A , Hand and Arm Bimanual Intensive Therapy Including Lower Extremity, GROUP-B , Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Diplegic Cerebral Palsy With Spasticity
Effects of Ankle Mobilization on Body Structure, Function, Activities and Participation of Children With Cerebral Palsy
Cerebral palsy is the most common motor disability of childhood (Suvanand et al 1997). By definition CP is a static encephalopathy, but the musculoskeletal pathology is a major concern .
- Trial name
- NCT05500924
- Testing
- Intervention group
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University