Clinical trials: Dipyrone
Intrapartum Fever, Chorioamnionitis
Antipyretic Treatment for Intrapartum Fever: Dipyrone vs Acetaminophen (RCT)
Chorioamnionitis, or intraamniotic infection, is a common condition affecting 2-5% of all term births. This condition poses well-recognized maternal and neonatal risks, and entails a series of clinical management decisions…
- Trial name
- PARADIP (NCT06950840)
- Testing
- Acetaminophen, dipyrone
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- Wolfson Medical Center
Analgesia, Surgery
Evaluation of the Added Value of Metamizole to Standard Post-operative Treatment After Ambulant Surgery
The aim of this study is to investigate if the addition of metamizole to the standard post-operative treatment, i.e. paracetamol and ibuprofen, is superior in reducing post-operative pain on day 1 after ambulatory surgery…
- Conditions
- Analgesia, Surgery, Recovery
- Trial name
- NCT04082728
- Testing
- Metamizole
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Jessa Hospital
Preeclampsia
Ibuprofen vs Dipyrone After C-section in Preeclampsia
The goal of this randomized, triple-masked clinical trial is to compare the effectiveness and safety of the use of ibuprofen versus dipyrone for postoperative analgesia in postpartum women with preeclampsia undergoing cesarean…
- Trial name
- DIPROFEN (NCT05586373)
- Testing
- medication 1, medication 2
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Oncologic Diseases, Coagulation Defect
Study Protocol: Impact of Metamizole (Optalgin®) on Anti-Xa Concentrations in Oncology Patients Receiving DOACs
Evaluation of the Effect of metamizole (Optalgin®) on Anti-Xa Levels in Oncology Patients Receiving Direct Oral Anticoagulants (DOACs)
- Conditions
- Oncologic Diseases, Coagulation Defect, Pain Management
- Trial name
- NCT07384013
- Testing
- metamizole
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Lumbar Sciatic Pain
Efficacy and Safety of Injectable Association of Dexamethasone, Dipyrone and Hydrocobalamin in Lumbar Sciatic Pain
A phase III, randomized, multicenter, open label clinical trial to evaluate efficacy and safety of the injectable association of dexamethasone, dipyrone, and hydroxocobalamin in lumbar sciatic pain.
- Trial name
- Dextra (NCT01147289)
- Testing
- Dextralgen, Meloxicam
- Where
- 6 sites in Brazil
- Volunteers
- 280 people
- Sponsor
- Eurofarma Laboratorios S.A.
Aortic Aneurysm, Postoperative Nausea and Vomiting
AoA Guided Thoracic Epidural Analgesia for Abdominal Aortic Repair
The aim of this randomized trial is to assess the efficacy of analgesia using either thoracic epidural or intravenous infusions for open lumbar infrarenal aortic aneurys repair and compare Numerical Rating Scale (NRS) with…
- Conditions
- Aortic Aneurysm, Postoperative Nausea and Vomiting, Postoperative Pain, Haemodynamic Stability
- Trial name
- AoA-AAA (NCT06609993)
- Testing
- intravenous rescue opioid analgesia using fentanyl, intravenous rescue atropine administration, intravenous rescue urapidil administration
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Michał Stasiowski
Pain, Postoperative
Potential Benefit of the Combination of Metamizole and Ibuprofen After Third Lower Molar Extraction
Postoperative pain is common and particularly outpatients may experience unsatisfactory pain relief. This randomized, double-blind, crossover study of postoperative pain in outpatients undergoing split-mouth, third lower molar…
- Trial name
- NovIbu (NCT02686021)
- Testing
- Metamizole and Ibuprofen
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University Hospital, Basel, Switzerland
Gastroenteritis
Optimal Analgesia in Acute Gastroenteritis
The purpose of this study is to find out an optimal way of analgesia in case of acute infectious gastroenteritis the investigators are going to compare two medicines that are used on everyday basis (without being ever before…
- Trial name
- NCT02711241
- Testing
- Dipyrone, Papaverine
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Hadassah Medical Organization
Lumbar Disc Disease
SPI-directed Analgesia for Lumbar Discectomy
The aim of this randomized trial is to assess the efficacy of analgesia for lumbar discectomy and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively.
- Trial name
- SPI (NCT02971540)
- Testing
- Metamizol, Tramadol, Bupivacaine
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Silesia
Scorpion Stings, Pain
Comparison of Lysine Clonixinate, Ketorolac and Metamizole Sodium in Scorpion Stings
The cases of scorpion stings are matters of medical importance, where Mexico is considered as one of the main countries of such public health problem.
- Conditions
- Scorpion Stings, Pain, Analgesic
- Trial name
- NCT03943199
- Testing
- Visual Analogue Scale for pain
- Where
- Mexico
- Volunteers
- 160 people
- Sponsor
- Mexican Red Cross
Pain
Metamizol for the Treatment of Neoplastic Chronic Pain
Study to evaluate the efficacy of metamizole in reducing morphine requirements in patients with moderate to severe chronic cancer pain in comparison to administration of placebo or diclofenac.
- Trial name
- NCT02181920
- Testing
- Metamizole, Diclofenac
- Volunteers
- 6 people
- Sponsor
- Boehringer Ingelheim
Healthy
Effect of Metamizole (Dipyrone) on Renal Function in Salt-depleted Healthy Subjects
The planned study is a single-center, randomized, open-label parallel group study in 16 healthy male subjects. Study subjects will be randomly allocated either to the metamizole group (1) or to the naproxen group (2).
- Trial name
- NCT01995006
- Testing
- metamizole, Naproxen
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Advanced Chronic Liver Disease, Portal Hypertension Related to Cirrhosis
Program to Avoid NSAIDs in Patients With Advanced Chronic Liver Disease
This study aims to implement measures to avoid the use of NSAIDs or metamizole in patients with advanced chronic liver disease (ACLD) scheduled for major surgery, which are contraindicated due to increased risk of renal…
- Trial name
- NCT07249294
- Testing
- Multidisciplinary support program
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Parc de Salut Mar
Postoperative Pain, Analgesia
Evaluation of the Added Value of Metamizole to Standard Postoperative Treatment After Ambulant Shoulder Surgery
This study aims to investigate if the combination of metamizole and paracetamol is superior in reducing post-operative pain on day 1 after ambulatory shoulder surgery where the use of NSAIDs is prohibited compared to paracetamol…
- Conditions
- Postoperative Pain, Analgesia, Surgery
- Trial name
- Metamizole003 (NCT04703257)
- Testing
- Metamizole
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Jessa Hospital
Ischemic Stroke
Antiplatelet Effects in Stroke-Patients
Many patients suffer from acute and chronic pain. The incidence of chronic pain correlates with increased age. Most of patients rely on analgesic medication to control the pain.
- Trial name
- NCT02148939
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Inhibition, Induction
Pharmacokinetic Interactions of Metamizole (Dipyrone) in Healthy Subjects
Investigators conducted a single center, two-phased, open, controlled pharmacokinetic study to investigate the drug-drug interaction potential of metamizole. For this reason, healthy male volunteers were screened.
- Conditions
- Inhibition, Induction, Drug-Drug Interaction
- Trial name
- NCT03990129
- Testing
- Metamizole
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland