Clinical trials: Disability, Evaluation
Infantile Refsum's Disease, Zellweger Syndrome
Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid
OBJECTIVES: I. To Evaluate the therapeutic efficacy of cholic acid during provision of compassionate treatment to patients with identified inborn errors of bile acid synthesis and metabolism II.
- Conditions
- Infantile Refsum's Disease, Zellweger Syndrome, Adrenoleukodystrophy, Peroxisomal Disorders
- Trial name
- NCT00007020
- Testing
- Cholic Acids
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Mirum Pharmaceuticals, Inc.
Tetraplegia
Clinical Trial to Evaluate the Safety and Efficacy of an Implantable Neural Acquisitor & Stimulator System in Patients With Motor Disability
Through brain-computer interface alternative technology, patients can control the external equipment（wheelchairs, robotic arms, the WeChat app and other physical aids）with brain signals to improve the patients quality of life.
- Trial name
- NCT05920174
- Testing
- NEO
- Where
- 4 sites in China
- Volunteers
- 9 people
- Sponsor
- Neuracle Medical Technology(Shanghai) Co.,Ltd.
Low Back Pain
Kinematical Evaluation of Lumbar Rotation in Chronic Low Back Pain
Low back pain (LBP) is considered one of the most common musculoskeletal disorders in modern society, resulting in substantial costs to society.
- Trial name
- NCT01217554
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Disability Physical, Neck Pain
Evaluation of the Relationship Between Neck Pain and Ergonomic Factors in Office Workers
The current study aimed to explore the associations between disability levels and occupational risk factors in computer-using office workers with neck pain.
- Conditions
- Disability Physical, Neck Pain, Ergonomic Factors
- Trial name
- NCT04821024
- Testing
- A self-administered questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Kinesiophobia, Disability
Kinesiophobia in Patients With Chronic Low Back Pain
Low back pain is an important health problem that is common in public and causes serious socio-economic losses. Low back pain that persists for more than 12 weeks is defined as chronic low back pain.
- Conditions
- Kinesiophobia, Disability, Quality of Life
- Trial name
- NCT06190041
- Volunteers
- 200 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Multiple Sclerosis, Pathologic Processes
Disability, MRI Lesions and Thickness of Retinal Fibers: Evaluation 15 Years After a First Episode of Demyelination
Knowledge of the evolution of multiple sclerosis (MS) and its long-term prognostic factors is essential to guide the therapeutic management.
- Conditions
- Multiple Sclerosis, Pathologic Processes, Tomography, Optical Coherence, Magnetic Resonance Imaging
- Trial name
- DB-SEP15 (NCT03268096)
- Testing
- Cerebral MRI and Optical Coherence Tomography
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Disabilities Physical, Sensory Disorder
Systematic Development and Test-Retest Reliability of EISA
The purpose of this proposed study, is the development and validation of EISA, a Self-report outcome measurement tool, for assessing the satisfaction of everyday functional needs, for consumers using Electronic Assistive Devices…
- Trial name
- EISA (NCT04797754)
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Pittsburgh
Developmental Delay, Body Perception
Investigation of the Effects of Basic Body Awareness Training on Motor Skills İn Children at Risk of Developmental Delay
The aim of this study is to investigate the effects of basic body awareness training on preschool children with developmental delays.
- Trial name
- NCT07054996
- Testing
- body awareness therapy, play-based exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Harran University
Leprosy, Disability Evaluation
Prevention of Disability: Proposal for a Guidance Manual for Leprosy Patients
Leprosy is an infectious disease of slow evolution, manifested primarily by signs and symptoms dermatoneurological with skin lesions and peripheral nerve, especially in the eyes, hands and feet.
- Conditions
- Leprosy, Disability Evaluation, Quality of Life
- Trial name
- NCT01006759
- Testing
- exercise and orientation
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo
Myofascial Pain Syndromes
Myofascial Release and Positional Release Techniques in Unilateral Trapezitis
Unilateral trapezitis is characterized by upper trapezius myofascial pain and trigger points and commonly causes neck pain, restricted cervical range of motion (ROM), and functional disability.
- Trial name
- NCT07515352
- Testing
- Myofascial Release Technique, Positional Release Technique
- Where
- India
- Volunteers
- 30 people
- Sponsor
- King Saud University
Fragile X Syndrome
An Open Label Extension Study in Subjects With Fragile X Syndrome
This study will enroll subjects who have completed Protocols 209FX301, 209FX302, or are currently participating in Protocol 2202 into a long-term study in which all subjects will receive active drug (arbaclofen).
- Trial name
- 209FX303 (NCT01555333)
- Testing
- arbaclofen
- Where
- 23 sites in United States
- Volunteers
- 357 people
- Sponsor
- Seaside Therapeutics, Inc.
Rett Syndrome
A Study to Evaluate Ketamine for the Treatment of Rett Syndrome
This 2 cohort, sequential, ascending dose study will assess the safety, tolerability and efficacy of oral ketamine dosed in a single 5-day BID regimen in addition to placebo, in a 4-week cross-over design in patients with Rett…
- Trial name
- NCT03633058
- Testing
- Ketamine
- Where
- 7 sites in United States
- Volunteers
- 23 people
- Sponsor
- Rett Syndrome Research Trust
Stroke, Amyotrophic Lateral Sclerosis
Auto-calibrating System for Upper Limb Disability Assessment, Neurological and Occupational Rehabilitation
This interventional, multicenter, low-intervention clinical trial aims to evaluate the usability, feasibility, safety, and preliminary clinical impact of a robotic rehabilitation system designed for upper limb rehabilitation in…
- Conditions
- Stroke, Amyotrophic Lateral Sclerosis, PARKINSON DISEASE (Disorder), Mild Cognitive Impairment (MCI)
- Trial name
- ASULDAR (NCT07636538)
- Testing
- Auto-calibrating System for Upper Limb disability Assessment, neurological and occupational Rehabilitation, conventional therapy
- Volunteers
- 30 people
- Sponsor
- University of Pavia
Diet Habits, Body Composition
Body Composition and Lifestyles in Athletes With Disabilities
Disability involves limitations that affect mobility and the ability to perform daily activities and achieve competitive goals. It is expected that disability has a significant impact on body composition, including reductions in…
- Conditions
- Diet Habits, Body Composition, Athlete Assessment, Sport Nutrition
- Trial name
- PADES (NCT07464899)
- Testing
- Diet, body composition, Physical activity
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Low Back Pain, Mechanical, Pelvic Floor Muscle Weakness
Investigation of Pelvic Floor Muscle Strength in Low Back Pain
To evaluate the effect of pelvic floor muscle strength on women with non-specific low back pain
- Conditions
- Low Back Pain, Mechanical, Pelvic Floor Muscle Weakness, Non-specific Low Back Pain, Disability Physical
- Trial name
- NCT05811572
- Testing
- measurement of pelvic floor muscle with perinometer
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Gulhan Yilmaz Gokmen
Hearing Loss
Thai-version Five Minute Hearing Test
This study is aimed to test the sensitivity and specificity of Thai-version Five Minutes Hearing test against the audiometry to screen hearing problem in community.
- Trial name
- Thai_FMHT (NCT01408992)
- Testing
- Audiometry, Thai-Five Minute Hearing Test
- Where
- Thailand
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Brain Injuries, Cerebral Palsy
Program Intensive Habilitation (PIH) for Young Children With Early Brain Damage
By longitudinal, prospective research in children with neurodisabilities including severe motor impairments and their parents to explore the beneficial effects of participating in an intensive habilitation program on the child's…
- Conditions
- Brain Injuries, Cerebral Palsy, Motor Skills Disorders, Empowerment
- Trial name
- PIHMulti (NCT05093777)
- Testing
- Program Intensified Habilitation, Habilitation as usual
- Where
- Norway
- Volunteers
- 93 people
- Sponsor
- Sorlandet Hospital HF
Myopia
A Prospective Evaluation of Contrast Sensitivity and Disability Glare in Refractive Surgery, a Sub-Study of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)
The purpose of this study is to conduct a prospective assessment of small target contrast sensitivity and disability glare in refractive surgery.
- Trial name
- NCT00413868
- Testing
- LASIK, PRK, Small target contrast sensitivity and disability glare
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Chronic Disabling, COVID-19
COVID-19 Outbreak Consequences for Outpatients Followed in PRM
Objectives This survey aims at reporting the immediate impact of the COVID-19 epidemic on outpatients followed in Physical and Rehabilitation Medicine (PRM).
- Trial name
- Handicall (NCT04384406)
- Where
- France
- Volunteers
- 467 people
- Sponsor
- University Hospital, Montpellier
Postpartum Lumbopelvic Pain
Investigation the Effects of Stabilization Exercises on Pain, Disability and Activity of Pelvic Floor Muscles in Patients With Postpartum Lumbopelvic Pain
The purpose of this study was to evaluate the effects of stabilization exercises on pain, disability and pelvic floor muscles function in patients with lumbopelvic pain.
- Trial name
- NCT03030846
- Testing
- Stabilization exercise, Control group
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Zahedan University of Medical Sciences