Clinical trials: Disc Displacement
Lumbar Disc Herniation
QLB vs ESPB for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle to anesthetize the thoracolumbar nerves.
- Trial name
- NCT06477198
- Testing
- QLB, ESPB, Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Lumbar Radiculopathy, Lumbar Herniated Disk
Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?
Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy
- Trial name
- NCT07411326
- Testing
- Intervention Group, Control group (Normal Saline) (C)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Lumbar Disc Herniation
RCT - Epidural Anesthetic Cocktail Following Endoscopic Lumbar Discectomy
The study aims to study the effect of intraoperative epidural application of anesthetic cocktail following endoscopic lumbar discectomy in improving postoperative pain, length of hospital stay, time at first dose analgesia…
- Trial name
- NCT05738759
- Testing
- Epidural Anesthetic Cocktail
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Lumbar Herniated Disc
Assesment of Epidural Platelet-Rich Plasma (PRP) Injection During Uniportal Endoscopic Lumbar Disc Herniation Excision on Residual Neuropathies
The aim of this study is to assess neuropathic pain in the lower limb at 6 months post-operation in patients who have undergone surgery for a lumbar disc herniation using single-port endoscopic discectomy combined with an…
- Trial name
- HERDISPLA (NCT07770750)
- Testing
- Uniportal endoscopic lumbar disc herniation removal
- Where
- France
- Volunteers
- 50 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Lumbar Disc Herniation With Radiculopathy
Comparison of the Effectiveness of Ultrasound-Guided Periradicular Injections in Patients With Lumbar Radicular Pain
This study aims to compare the effects of different ultrasound-guided periradicular injection solutions in patients with chronic unilateral radicular pain caused by a single-level lumbar disc herniation.
- Trial name
- NCT07771374
- Testing
- Lidocaine Hydrochloride 2% Injection Solution, Dexamethasone 4 Mg/mL Injectable Solution, Dextrose 5% Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Temporomandibular Disorder (TMD), Internal Derangement
Computer Guided Single Needle Arthrocentesis
The intra-articular injection is considered the first line of minimally invasive treatment in temporomandibular joint with internal derangement (TMJ-ID) patients who do not respond to conservative treatment.
- Conditions
- Temporomandibular Disorder (TMD), Internal Derangement, Anterior Disc Displacement
- Trial name
- NCT07306936
- Testing
- Computer-guided single needle arthrocentesis, conventional free hand single needle arthrocentesis
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Alexandria University
Lumbar Disc Herniation, Sciatica
Bilateral Sacroiliac Joint (SIJ) Injection in Lumbar Disc Prolapse
Bilateral sacroiliac joint injection in symptomatic lumbar disc prolapse under ultrasound guidance and studying the effect of this technique on pain, spine mobility and activity of daily living.
- Conditions
- Lumbar Disc Herniation, Sciatica, Low Back Pain, Mechanical, Spine Stiffness
- Trial name
- NCT04326699
- Testing
- Bilateral SIJ injection
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Sohag University
Intervertebral Disc Displacement, Electromyography
EMG Finding According to the Type of Lumbar Disc Herniation
Disc herniation is a common cause of low back pain and leg pain. Electromyography is the only test that can objectively examine nerve damage caused by a lumbar disc herniation.
- Trial name
- NCT04538807
- Testing
- electromyography
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Yeungnam University Hospital
Lumbar Disc Herniation
STA363 in the Treatment of Lumbar Disc Herniation
The goal of this clinical trial is to establish safety and tolerability of STA363 injected into a herniated intervertebral disc in patients with sciatica due to disc herniation. The main questions the trial aims to answer are: 1.
- Trial name
- NCT06022263
- Testing
- Lactic Acid
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Stayble Therapeutics
Lumbar Disc Herniation
A Comparison Between Biportal and Uniportal Endoscopic Lumbar Discectomy
This study aims to provide a detailed comparison between different methods of lumbar discectomy by the use of different types of spine endoscopy to evaluate the benefits and drawbacks of each type
- Trial name
- NCT07151651
- Testing
- Endoscopic lumbar discectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Lumbar Disc Degeneration, Lumbar Disc Herniation
Human Umbilical Cord Mesenchymal Stem Cells For the Treatment of Lumbar Disc Degeneration Disease
This study aims to investigate the safety and efficiency of Human Umbilical Cord Mesenchymal Stem Cells (hUCMSC) for treating lumbar disc degeneration diseases.
- Trial name
- NCT04414592
- Testing
- human umbilical cord mesenchymal stem cells
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
TMJ Disorder
Condylar Position Changes in Anterior Disc Displacement with Reduction
the goal of this clinical trial is to know if TMJ lavage does change the condyle position in patients diagnosed with unilateral anterior disc displacement with reduction.
- Trial name
- NCT06856811
- Testing
- tmj lavage with ringer lactate solution
- Where
- Yemen
- Volunteers
- 14 people
- Sponsor
- Sana'a University
Temporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction
Comparative Assessment of Arthrocentesis Methods in TMJ Disorders
Temporomandibular disorders (TMD) are common conditions in society, characterised by symptoms such as pain, limited movement and joint noises, which negatively affect an individual's quality of life.
- Trial name
- NCT07327099
- Testing
- Y-shaped cannula without a source, Y-shaped cannula with a source
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Helin Merve Özalp
TMJ Disc Disorder
Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials
comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.
- Trial name
- NCT06441279
- Testing
- intra-articular injection with Platelet lysate (PL)., intra-articular injection with Hyaluronic Acid.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pain, Myofacial, Pain, Neck
Does Dry Needling Affect Treatment Outcomes of Interlaminar Epidural Steroid Injection in Cervical Disc Herniation?
Chronic neck pain is among the most frequently seen chronic painful conditions. As an important cause of disability, chronic neck pain is a musculoskeletal disorder that negatively affects quality of life.
- Conditions
- Pain, Myofacial, Pain, Neck, Pain, Chronic
- Trial name
- NCT04914637
- Testing
- Cervical interlaminar epidural steroid injection, Dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Lumbar Disc Herniation
VR Therapy Effects in Lumbar Disc Herniation
This study aims to evaluate the effects of incorporating virtual reality (VR) therapy into routine physical therapy (RPT) on balance, pain, kinesiophobia, quality of life, and depression in individuals diagnosed with lumbar disc…
- Trial name
- NCT07309627
- Testing
- Conventional Physiotherapy, VR
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Uskudar University
Interleukines
Study of Cytokines Serum Levels in Chronic Low Back Pain
The purpose of this study is to: evaluate if there is an association between elevated levels of cytokines and chronic pain due to herniated disk disease measured cytokines levels in chronic low back pain and in healthy subjects.
- Trial name
- cytokine (NCT00991042)
- Testing
- blood collect
- Where
- Brazil
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Intervertebral Disc Herniation, Stiffness; Spine
Cervical Changes by 4h of Hyper-buoyancy Flotation and Followed by 15 Mins 1g Re-loading
Study with the aim to see the effect on a space ground anaologue, Hyperbuoyancy Floatation (HBF) on cervical column.
- Trial name
- NCT05296200
- Testing
- Hyperbuoyancy Floatation
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Universidad Autonoma de Madrid
Disc Herniation, Surgery
Exercise After Lumbar Disc Herniation Surgery
Physical therapy and rehabilitation may improve low back pain and quality of life after lumbar disc herniation. But there is not any agreement of its optimal start time, and rehabilitative methods.
- Trial name
- NCT06046781
- Testing
- physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people
- Sponsor
- Istanbul Medeniyet University