Clinical trials: Disc Herniations
Lumbar Disc Herniation
Comparison of Cyriax Manipulation and Decompression in LDP
In this study, compare the effects of Cyriax manipulation and Decompression in patient with lumber disc prolapseThis research will provide an important addition to the evidence based treatment intervention in physical therapy in…
- Trial name
- NCT04653870
- Testing
- cyriax manipulation lumber, lumber decompression
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Lumbar Disc Herniation, Lumbosacral Radiculopathy
Comparing Three Epidural Steroid Injection Approaches for Lumbar Radicular Pain
This study will compare three fluoroscopy-guided epidural steroid injection approaches for adults with unilateral lumbosacral radicular pain caused by lumbar disc herniation.
- Trial name
- NCT07813988
- Testing
- High-Volume Parasagittal Interlaminar Epidural Steroid Injection, Low-Volume Parasagittal Interlaminar Epidural Steroid Injection, Transforaminal epidural steroid injection
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Benha University
Neck Pain, Cervical Disc Herniation
Comparison of Conservative Treatment and Graston and Cup Applications in Patients With Cervical Disc Herniation
The aim of the study is to examine the effects of graston and dry cupping techniques applied in addition to the conservative treatment program on neck awareness, grip strength, balance and sleep quality in patients with cervical…
- Trial name
- NCT06003907
- Testing
- conventional, traditional and complementary medicine methods
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Uskudar University
Lumbar Disc Herniation
Compare the Effects of Decompression on Lumber Disc Protrusion Patient
This is an RCT study in which 60 participant are included and half of the participant are randomized via lottery method in control and experimental group after fulfilling the inclusion criteria.
- Trial name
- NCT04860609
- Testing
- Conventional Physiotherapy, Lumber Spinal Decompression
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Pain, Pain Postoperative
The Effects of Body Mass Index on Erector Spinae Plane Block Analgesia
In recent years, obesity has become one of the leading health problems worldwide. It is known that obesity can cause various diseases and negatively impact the quality of life.
- Conditions
- Pain, Pain Postoperative, Pain Acute, Erector Spinae Plane Block
- Trial name
- NCT06257953
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Lumbar Disc Herniation
Preoperative Magnetic Resonance Imaging Abnormalities Predictive of Lumbar Herniation Recurrence
There are currently no standard criteria for evaluating the risk of recurrent disk herniation following surgical repair. This study investigated the predictive values of five presurgical imaging parameters, paraspinal muscle…
- Trial name
- NCT05246241
- Testing
- magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people
- Sponsor
- Ataturk University
Lumbar and Other Intervertebral Disc Disorders With Radiculopathy
Epidural Clonidine for Lumbosacral Radiculopathy
This was a randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy.
- Trial name
- NCT00588354
- Testing
- Clonidine, Triamcinolone hexacetonide, Lidocaine HCl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Disc Herniation, Cervical Radiculopathy
Mobilization With Movement vs. Neural Mobilization on Nerve Root Function in Patients With Cervical Radiculopathy
This study will be conducted to compare the effect of sustained natural apophyseal glides (SNAGS) versus neural mobilization on clinical outcomes such as 1- nerve root function in the form of: (A) peak to peak amplitude; (B)…
- Conditions
- Disc Herniation, Cervical Radiculopathy, Cervical Radiculopathy at C5 Nerve Root, Cervical Radiculopathy at C6 Nerve Root
- Trial name
- NCT05803954
- Testing
- Sustained natural apophyseal glides (SNAGS), Neural mobilization, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Cairo University
Lumbar Disc Herniation
Effects of Exercise in Lumbal Disc Herniation
Lumbar disc herniation, which causes 5% of all low back pain, is the rupture of the annulus fibrosis in the intervertebral disc in the lumbar region and the protrusion of the nucleus pulposus at various degrees, and as a result…
- Trial name
- NCT05927051
- Testing
- Stabilization exercises, McKenzie exercises, Home exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Firat University
Degenerative Disc Disease, Chronic Low-back Pain
"Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2)
This study will be a prospective, open-label, multi-center study including 72 patients that will collect additional safety and efficacy data for the Spinal Stabilization Technologies PerQdisc Nucleus Replacement System.
- Trial name
- LOPAIN2 (NCT05508360)
- Testing
- PerQdisc Nucleus Replacement System
- Where
- 11 sites in Colombia, Costa Rica and 3 more
- Volunteers
- 72 people
- Sponsor
- Spinal Stabilization Technologies
Low Back Pain, Disc, Herniated
Motor Control Mechanisms by CNS of Tuina in Patients With Lumbar Disk Herniation
Lumbar disk herniation (LDH)is a prevalent health problem around the world. It can cause symptoms of low back pain, numbness or weakness.The understanding of low back pain in traditional Chinese medicine(TCM) theory"unbalanced…
- Trial name
- NCT03475095
- Testing
- Tuina
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Lumbar Disc Herniation, Radial Artery
A Diagnostic Test of Abnormal Sound Waves in Modern Pulsology of Lumbar Disc Herniation
The purpose of this study is to use the " Pulse Detection System of Sound Waves " to collect the pulse information of recruited subjects, and to extract characteristic pulse information by multi-scale entropy, Fourier transform…
- Trial name
- NCT04859712
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Sciatica
Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients With Sciatica
Disc herniation, stenosis of the spine and spondylolisthesis are the common causes of radiculitis in medical practice today, and can cause symptoms of sciatica.
- Trial name
- NCT03801512
- Testing
- Steroid, Acupuncture, Platelet Rich Plasma
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Medical University Hospital
Lumbar Disc Herniation
Post-marketing Clinical Follow-up of the Medical Device DIVA®
Observational, ambispective, longitudinal, comparative, open, multicentric study. The main objective is to compare the performance of care in patients operated with and without DIVA®.
- Trial name
- NCT05277818
- Testing
- Surgery lumbar disc herniation
- Where
- France
- Volunteers
- 822 people
- Sponsor
- SC Medica
Lumbar Disc Herniation, Anular Tear of Lumbar Disc
Incidence of Large Annular Defects in Primary Lumbar Discectomy Patients
Lumbar discectomy study, collection and evaluation of incidence of large annular defects.
- Conditions
- Lumbar Disc Herniation, Anular Tear of Lumbar Disc, Nucleus Pulp Hernia;Lumbosac
- Trial name
- USLSI (NCT03252691)
- Where
- United States
- Sponsor
- Intrinsic Therapeutics
Low Back Pain, Disk Prolapse
Effects of Sustained Natural Apophyseal Glides in Combination With McKenzie Extension Protocol in the Management of Discogenic Low Back Pain
Lumbar degenerative disc disease and discogenic low back pain is comparatively common and disabling musculoskeletal condition. McKenzie's extension protocol is considered to be the gold standard physical therapy treatment for…
- Conditions
- Low Back Pain, Disk Prolapse, Disk Herniated Lumbar, Sciatic Radiculopathy
- Trial name
- NCT05314049
- Testing
- Mckenzie Extension Protocol, Lumbar SNAGs, inferential therapy
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Impact of Muscle Degeneration in Chronic Low Back Pain
Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Radiculopathy, Back Pain
- Trial name
- NCT04273828
- Testing
- Lumbar decompressive surgery
- Where
- Brazil
- Volunteers
- 168 people
- Sponsor
- Hospital Israelita Albert Einstein
Lumbar Disc Herniation
The Effect of Progressive Relaxation Exercise on Pain and Kinesiophobia After Lumbar Disc Herniation Surgery
We aimed to assess the influence of progressive muscle relaxation exercise on kinesiophobia and pain during after lumbar disc surgery using the Visual Analog Scale (VAS) and the Tampa Kinesiophobia Scale in a prospective…
- Trial name
- NCT05288634
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Aksaray University
Cervical Disc Herniation, Pain, Neuropathic
Effect of the Cervical Interlaminar Epidural Steroid Injection on Quality of Life, Pain and Disability
To evaluate the effect of cervical interlaminar epidural steroid injections on the neuropathic pain, quality of life and disability patients with cervical radiculopathy.
- Trial name
- NCT04235478
- Testing
- Combination Product: triamcinolone and saline
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Marmara University
Cervical Radiculopathy, Cervical Radicular Pain
Effect of Myofascial Release Technique in Patients with Unilateral Cervical Radiculopathy
The aim of the study is to investigate the effectiveness of myofascial release technique on pain, range of motion, muscle strength, functionality and quality of life in individuals diagnosed with cervical radiculopathy with…
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Cervical; Hernia, Cervical Disc Disease
- Trial name
- NCT04597112
- Testing
- Myofascial Release Technique, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital