Clinical trials: Discoloured Teeth
Teeth Color, Teeth Staining
A Clinical Study to Evaluate the Stain Reduction Efficacy of a Non-Fluoride Tooth Whitening Dentifrice Containing Nano-Hydroxyapatite (nHAP) and a High Cleaning Silica Abrasive System Compared to a Commercial Fluoride Non-Whitening Dentifrice as a Negative Control
To determine whether brushing with a non-fluoride tooth whitening dentifrice containing nHAP and a high cleaning silica system produces a greater level of stain reduction as indicated by the Modified Lobene Stain Index (MLSI) for…
- Trial name
- NCT07214038
- Testing
- toothpaste
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Discoloration, Tooth
Effect of Glutathione vs KI in Reducing SDF Staining When Used in Treatment of Primary Carious Teeth
Although black staining is considered a drawback that is clinically observed following SDF application and is the main primary barrier for its use clinically .
- Trial name
- NCT04816487
- Testing
- Potassium Iodide or Glutathione
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth
A Comparative Clinical Study Assessing Dentin Thickness and Discoloration in Deep Carious Lesions Treated With Biodentine Alone Versus Diode Laser Pre-treatment Followed by Biodentine
This interventional clinical study aims to compare dentin thickness preservation and tooth discoloration in deep carious lesions treated with Biodentine alone versus diode laser pre-treatment followed by Biodentine.
- Conditions
- Patients With Deep Carious Lesions, Deep Caries Lesion of Pemanent Teeth, Deep Carious Lesion
- Trial name
- NCT07358442
- Testing
- Biodentin, Diode laser
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Misr International University
Tooth Discoloration, Tooth Fractures
Patient Satisfaction of Glazed IPS Empress CAD Versus Glazed Celtra Duo Ceramic Laminate Veneers
The most frequent reason for failure of laminate veneers made of glass ceramics (feldspathic, leucite based and lithium silicate based ceramics) was fracture of the ceramic, Therefore, ceramic materials that have higher fracture…
- Trial name
- NCT03129711
- Testing
- glazed Celtra Duo, IPS Empress CAD
- Volunteers
- 36 people
- Sponsor
- Cairo University
Endodontically Treated Teeth, Root Canal Infection
Tooth Crown Discoloration Caused by Endodontic Treatment
The color change of endodontically treated teeth is a common concern in clinical practice. The objective of this study will be to evaluate, in vivo, the color change (ΔE00) caused by endodontic treatment.
- Conditions
- Endodontically Treated Teeth, Root Canal Infection, Tooth Discoloration
- Trial name
- NCT03841370
- Testing
- endodontic treatment
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Molar Incisor Hypomineralisation, Enamel Hypomineralization
Comparison of Two Minimally Invasive Approaches for Masking Molar-Incisor Hypomineralization Opacities
This clinical study aimed to compare the effectiveness of two minimally invasive approaches for masking molar-incisor hypomineralization (MIH) opacities and to evaluate esthetic perceptions of children and their parents.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypomineralization, Tooth Discoloration
- Trial name
- NCT07494682
- Testing
- Resin infiltration, Etch Bleach Seal Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Tooth Discoloration
Efficacy of Teeth Whitening Product Offerings in Adults
This is a 30 day randomized, parallel comparative trial where participants with tooth shade of C2 or darker will be assigned to one of five groups.
- Trial name
- NCT04124068
- Testing
- Hydrogen peroxide teeth whitening gel, GLO Brilliant Teeth Whitening Device, GLO Lit Teeth Whitening Device
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Glo Science, Inc.
Teeth Sensitivity, Tooth Discoloration
Efficacy of CPP-ACP on Bleaching Related Sensitivity
Objective: The purpose of this randomized controlled split-mouth clinical trial was to evaluate the effectiveness of MI paste in reducing sensitivity associated vital bleaching.
- Trial name
- NCT04112706
- Testing
- CPP-ACP
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of New England
Tooth Discoloration
Clinical Effectiveness of In-office Bleaching Activated With a LED/Laser Device
There is a controversy in the dentistry literature about how the use of associated light to activate 35% hydrogen peroxide gel during in-office tooth bleaching may increase the bleaching effectiveness.
- Trial name
- NCT01231243
- Testing
- in-office bleaching with/without light
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Tooth Discoloration, Tooth Fractures
One Year Clinical Evaluation of IPS Empress CAD Versus Polished Celtra Duo Ceramic Laminate Veneers
When restoring teeth with IPS Empress laminate veneers, fracture of restorations may occur. So, material with higher mechanical properties is required.
- Conditions
- Tooth Discoloration, Tooth Fractures, Diastema
- Trial name
- NCT03136276
- Testing
- IPS Empress CAD, polished Celtra Duo
- Volunteers
- 36 people
- Sponsor
- Cairo University
Black Staining
Comparison of Erythritol Air-Polishing and Conventional Polishing Following Ultrasonic Scaling on the Relapse of Chromogenic Tooth Staining in Children
The goal of this randomized clinical trial is to compare the effect of erythritol air-polishing and conventional polishing following ultrasonic scaling on the relapse of chromogenic tooth staining in children aged 4-13 years…
- Trial name
- NCT07730658
- Testing
- Guided Biofilm Therapy with erythritol, Conventional Polishing
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Marmara University
Tooth Discoloration
Evaluation of Template Assisted Monochromatic Structural Colored Versus Universal Multi-Shade Direct Composite Veneers
The aim of this study was to conduct a clinical trial utilizing a modified split-mouth, double-blinded, randomized strategy to clinically assess template assisted one shade structural colored versus universal multi-shade direct…
- Trial name
- NCT06543654
- Testing
- Omnichroma, Ceram. X Spectra
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tanta University
Endodontically Treated Teeth, Tooth Discoloration
Color Dental Alteration Caused by Endodontic Treatment
The color change of endodontically treated teeth is a common concern in clinical practice. The objective of this study will be to evaluate, in vivo, the color change (ΔE00) caused by endodontic treatment.
- Conditions
- Endodontically Treated Teeth, Tooth Discoloration, Root Canal Infection
- Trial name
- NCT03841877
- Testing
- endodontic treatment
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Tooth Discoloration
Phycosocial Impact of Bleaching Teeth
58 patients between 18 and 76 years who attended the Operative Dentistry Clinic at Dental School, Universidad de Chile, were included in the study.
- Trial name
- PSYBLE (NCT02605239)
- Testing
- Bleaching teeth
- Where
- Chile
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Chile
Healthy Volunteers, Discoloration of Teeth
Evaluation of Tooth Sensitivity and Whitening Effects of Different Content Teeth Whitening Agents
The goal of this clinical study is to evaluate the success of different whitening agents in whitening teeth in healthy volunteers aged 18-50. Also, patients' tooth sensitivity will be assessed after application.
- Conditions
- Healthy Volunteers, Discoloration of Teeth, Bleaching Sensitivity
- Trial name
- NCT06855940
- Testing
- Bleaching Agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Betül Tokat
Tooth Discoloration, Morphologic Change
Influence of Polishing After Bleaching on Color Change and Enamel Morphology
This trial evaluated the influence of polishing on enamel color change after in-office bleaching treatment. It also evaluated the influence of polishing on tooth morphology and sensitivity.
- Conditions
- Tooth Discoloration, Morphologic Change, Tooth Sensitivity
- Trial name
- NCT05635253
- Testing
- Hydrogen Peroxide 35%, Hydrogen Peroxide 35% + Polishing whitened teeth
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Tooth Discoloration
Efficacy of Manual Toothbrushes in Removing Tooth Stains
Efficacy of Manual Toothbrushes in Removing Tooth Stains: A 6-Week Clinical Research Study.
- Trial name
- NCT06486974
- Testing
- NaF, Na MFP
- Where
- Dominican Republic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Discoloration
450 nm Blue Diode Laser Versus Blue LED for In-Office Tooth Bleaching
Tooth discoloration is commonly managed using in-office dental bleaching. This randomized clinical trial compared the efficacy and safety of activating the same 35% hydrogen peroxide bleaching gel with either a 450 nm blue diode…
- Trial name
- NCT07870317
- Testing
- 450 nm Blue Diode Laser, Blue Light-Emitting Diode Lamp, 35% Hydrogen Peroxide Dental Bleaching Gel
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Misr University for Science and Technology
Mineral Trioxide Aggregate
Clinical and Radio-graphic Evaluation of Non-staining Bio-active Bio-ceramic (Neo MTA 2) in Revascularization
The study will compare the clinical and radio-graphic performance of newly introduced non-staining bio-active bio-ceramic (Neo MTA 2) versus White MTA used as coronal plug material in revascularization of non-vital immature…
- Trial name
- NCT06637761
- Testing
- NeoMTA2, WMTA
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Discoloration
Efectiveness of a Brief Protocol by a Low (6%) Concentration Gel Peroxide Hydrogen of Teeth Bleaching
The purpose of this clinical study was to evaluate, the effectiveness and sensitivity post-treatment of a 6% hydrogen peroxide with nitrogen-doped titanium dioxide light activated bleaching agent, the impact of shorter interval…
- Trial name
- Brief6% (NCT02603354)
- Testing
- peroxide gel tooth bleaching 6%
- Where
- Chile
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Chile