Clinical trials: Discomfort
Gastrointestinal Discomfort, Performance Status
A Safety/Tolerance Phase, Ascending Single Dose Study to Evaluate the Safety and Tolerability of G3P-01, a Food-Grade Pectic Product, in Healthy Volunteers
This is an interventional, open-label study to evaluate the safety, tolerability and PK of escalating single doses of G3P-01 in 10 healthy adult subjects.
- Trial name
- G3P-01-01 (NCT05296083)
- Testing
- G3P-01
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- SQ Innovation, Inc.
Menstrual Pain, Menstrual Discomfort
An Exploratory Investigation of Dietary Supplementation and the Effect on Common PMS and Menstrual Symptoms
Dietary supplementation is widely used to alleviate various symptoms of PMS and menstruation such as bloating and cramping. Providing a combination of synergistic dietary supplements is hypothesized to significantly reduce…
- Trial name
- NCT05019924
- Testing
- Semaine
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Vascular Access Complication, Catheter-Related Infections
BIP CVC in Access Center at Danderyd Hospital, Stockholm, Sweden
Primary objective of the study is to establish the incidence of all any catheter related complications in BIP CVC and standard CVC groups in patients requiring CVC.
- Conditions
- Vascular Access Complication, Catheter-Related Infections, Catheter Thrombosis, Catheter Blockage
- Trial name
- IMPROWE (NCT03976557)
- Testing
- BIP CVC, Standard CVC
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Bactiguard AB
Knee Discomfort
Hydrolyzed Fish Cartilage Effect on Knee Joint Functionality and Discomfort in Adult Population
This study is an exploratory, non-comparative, multi-centric trial in 30 free-living healthy male and female subjects with moderate knee joint discomfort and loss of functionality.
- Trial name
- NCT04420091
- Testing
- Cartidyss
- Where
- 2 sites in Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Abyss Ingredients
General Wellbeing, Gastrointestinal Health
Hemp Oil + User Experience Study
Presented as an online survey, this study seeks to better understand how Thorne customers are using and experiencing the new Hemp Oil + product and how they feel it compares in the marketplace.
- Conditions
- General Wellbeing, Gastrointestinal Health, Physical Discomfort, Sleep
- Trial name
- NCT04026672
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Thorne HealthTech, Inc
Ocular Discomfort
Evaluation of the VisuXL® Performance on Ocular Surface Discomfort
VisuXL® is a medical device that is effective in various ocular surface disorders (ocular dryness, changes in the continuity of the corneal and conjunctival surface, environmental stress, exposure to UV and ionizing radiation…
- Trial name
- NCT03844737
- Testing
- VisuXL®
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- VISUfarma SpA
Knee Discomfort, Knee Pain
Dietary Supplement for Joint: the OLE Study
This clinical study evaluates if the oral administration of Bonolive can contribute to the improvement of functionnality in healthy elderly people with knee discomfort.
- Trial name
- NCT03072108
- Testing
- Bonolive
- Where
- Belgium
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Joint Discomfort
Efficacy and Safety of b-2Cool on Adults With Joint Discomfort
This study evaluates the effects of 40 mg of b-2Cool, a food supplement rich in native type-II collagen, on healthy adults with joint discomfort.
- Trial name
- NCT02843620
- Testing
- b-2Cool
- Sponsor
- Bioiberica
Constipation, Gastrointestinal Discomfort
Clinical Evaluation of the Effects of EpiCor on Digestive Comfort
Previous in vitro studies suggest that EpiCor is well fermented in the colon and has prebiotic potential. The repeated long-term administration of low doses of EpiCor in the Simulator of the Human Intestinal Microbial Ecosystem…
- Trial name
- NCT03051399
- Testing
- EpiCor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ProDigest
Upper Gastric Discomfort
Effect of Consumption of Dairy Product on Upper Gastric Discomfort
The purpose of this study is to determine whether the consumption of test dairy products is effective in reducing upper gastric discomfort after 2 weeks of product consumption.
- Trial name
- NCT01422980
- Testing
- 1- Test dairy product containing specific ingredients, 2- Control dairy product without specific ingredients
- Where
- Argentina
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Abdominal Discomfort
Benefit and Tolerability of a Probiotic Product in Infants With Abdominal Discomfort
To demonstrate benefit and tolerability of a probiotic product in infants with abdominal discomfort.
- Trial name
- NCT01893814
- Testing
- Probiotics, Control
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- Probi AB
Knee Discomfort, Pain Physical Activity
Polyherbal Capsule Formulation for Joint Health
This is a multicenter, randomized, double-blind, placebo-controlled, study in subjects with exercise-related knee pain/discomfort to determine the efficacy of a polyherbal capsule compared to placebo capsule in improving exercise…
- Trial name
- NCT02157701
- Testing
- Polyherbal capsule
- Where
- 5 sites in United States
- Volunteers
- 108 people
- Sponsor
- NewChapter, Inc.
Abdominal Pain/ Discomfort, Slightly Constipation
Effect of Perilla Extract on Improvement on Gastrointestinal Discomfort
In the current study the effects of proprietary Perilla frutescens leaf extract in comparison to Maltodextrin, a fully digestible carbohydrate (placebo control), on gastrointestinal discomfort and bowel function were…
- Trial name
- NCT01931930
- Testing
- Perilla extract, Maltodextrin
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Amino Up Chemicals Co., Ltd.
Post Laser Vision Correction Pain and Discomfort
Laser Vision Correction Use of an Eye Shield for Maintaining Vision and Mitigating Pain
The purpose of this research is to determine if an investigational thin shield can effectively reduce discomfort following Laser Vision Correction.
- Trial name
- NCT01675375
- Testing
- Eye Shield
- Where
- 5 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Abdominal Discomfort, Bloating
Study to Evaluate a Probiotic in Healthy Subjects With a History of Abdominal Discomfort and Bloating
This is a multicenter, double-blind, randomized, placebo-controlled, 6-week study of a probiotic for abdominal discomfort and bloating in healthy subjects.
- Trial name
- NCT01099696
- Testing
- B. infantis 35624
- Where
- 10 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Ocular Discomfort
A Study to Evaluate the Clinical Performance of a Novel Multipurpose Solution
The objective of this study is to evaluate the clinical performance of Bausch \& Lomb investigational Multi-Purpose Solution compared to Ciba Vision Multi-Purpose Solution when used by wearers of silicone hydrogel or Group IV…
- Trial name
- NCT01024751
- Testing
- Bausch & Lomb Multi-Purpose Solution, Ciba's Multi-Purpose Solution
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated