Clinical trials: Disease, Acute
Pain, Acute, Pain, Chronic
Changes in Affective Pain Processing in Human Volunteers
The experience of pain is more than the conscious perception of nociceptive signals. Emotional and motivational aspects accompany pain, leading to its aversiveness and motivation for avoidance.
- Conditions
- Pain, Acute, Pain, Chronic, Low Back Pain
- Trial name
- NCT04280796
- Testing
- psychophysical tasks, cognitive task
- Where
- Switzerland
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- susanne becker
Acute Coronary Syndrome
Efficacy of Nursing Orientation to Reduce the Anxiety of Patients Undergoing Bed Bath
This study's general objective was to evaluate the efficacy of nursing orientation to reduce the anxiety of patients with acute coronary syndrome undergoing bed bath.
- Trial name
- NCT01724762
- Testing
- Nursing Orientation
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Federal University of São Paulo
Patients With Acute Stroke
Gait Trainer vs Traditional Physiotherapy in Acute Stroke
This is a trial aiming to evaluate the difference of effectiveness between two therapy methods in patients with acute stroke. The other aim is to use Navigated Brain Stimulation (NBS)to analyze changes in brain networks during…
- Trial name
- NCT00307762
- Testing
- intensified gait trainer
- Where
- Finland
- Volunteers
- 57 people
- Sponsor
- Kuopio University Hospital
Acute Graft Versus Host Disease
Clinical Trial With MSC for Graft Versus Host Disease Treatment
Sequential administration of MSCs obtained from adipose tissue is an effective and safe treatment for acute graft versus host disease refractory to first-line treatment.
- Trial name
- NCT02687646
- Testing
- Adult Allogeneic Mesenchymal cells from adipose tissue.
- Where
- 6 sites in Spain
- Volunteers
- 16 people
- Sponsor
- Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud
Stroke, Acute
The Intravascular Cooling in the Treatment of Stroke 2/3 Trial
The purpose of this trial is to determine whether the combination of thrombolysis and hypothermia is superior to thrombolysis alone for the treatment of acute ischemic stroke.
- Trial name
- ICTuS2/3 (NCT01123161)
- Testing
- hypothermia and anti-shivering treatment, Group1: IV t-PA and normothermia
- Where
- 31 sites in United States, Austria and 1 more
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Cholecystectomy, Laparoscopic, Cholangiopancreatography, Endoscopic Retrograde
Does Subtotal Cholecystectomy Rate for Acute Cholecystitis Change With a Previous ERCP?
Study is designed to investigate whether the history of ERCP is associated with subtotal cholecystectomy rates in patients underwent laparoscopic cholecystectomy operations with the diagnosis of acute cholecystitis.
- Trial name
- NCT05728073
- Testing
- ERCP
- Where
- Turkey (Türkiye)
- Volunteers
- 470 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Myocardial Infarction
Patients With Non-ST-segment Elevation Acute Coronary Syndrome
There are two types of acute coronary syndrome (ACS): ACS with persistent ST segment elevation (ACS ST +) and ACS without ST segment elevation (non-ST + ACS).
- Trial name
- SCA (NCT05159973)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Strasbourg, France
Respiratory Distress Syndrome
Evaluation of the Diagnostic Performance of Electrical Impedance Tomography to Detect Situations at Risk of Lesions Induced by Conventional Mechanical Ventilation in ARDS
Acute respiratory distress syndrome remains a serious condition, with a mortality rate of between 30 and 50%. The use of mechanical ventilation with small tidal volumes, and by limiting the plateau pressure in the respiratory…
- Trial name
- NCT02896673
- Testing
- ventilatory conditions and measures with scanner and EIT
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Hospices Civils de Lyon
Migraine
A Study of 3 Dosage Strengths of Almotriptan Malate (AXERT®) in the Treatment of Acute Migraine in Adolescents
The purpose of this study is to evaluate the effectiveness and safety of almotriptan malate (AXERT®) in treating acute migraine headaches in adolescents.
- Trial name
- NCT00210483
- Testing
- almotriptan malate
- Volunteers
- 866 people
- Sponsor
- Janssen-Ortho LLC
Respiratory Infection, COVID-19 Respiratory Infection
COVID-Like Illness Respiratory Pathogens. A Prospective Cohort on the COVID-19 Post-acute Condition
Identifying multiorgan sequalae and complications through high quality, prospective matched controlled studies throughout the course of COVID-19 is important for the acute and long-term management of patients and for health…
- Conditions
- Respiratory Infection, COVID-19 Respiratory Infection, Sequelae of; Infection
- Trial name
- CLEAR (NCT05047666)
- Volunteers
- 1,232 people
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Leukemia, Lymphoma
Donor Peripheral Stem Cell Transplant, Fludarabine, and Busulfan in Treating Patients With Hematologic Cancers
Giving chemotherapy drugs, such as fludarabine and busulfan, before a donor peripheral stem cell transplant helps stop the growth of cancer cells. It also stops the patient's immune system from rejecting the donor's stem cells.
- Conditions
- Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
- Trial name
- NCT00619645
- Testing
- busulfan, cyclosporine, fludarabine phosphate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of California, Davis
Severe Acute Pancreatitis
Effect of Epidural Anesthesia on Pancreatic Perfusion and Clinical Outcome in Patients With Severe Acute Pancreatitis
The aim of the study is to evaluate the safety, the potential beneficial effect of epidural anesthesia on pancreatic perfusion and clinical outcome of patients with severe acute pancreatitis.
- Trial name
- NCT01607996
- Testing
- Epidural anesthesia, Patient controlled intravenous analgesia
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
Myelofibrosis, Acute Leukemia
Peri-graft Cytokine Profile: Influence of Hematologic Disease and Donor Type
Cytokine profiles in the early post-transplant phase may influence the Development of early post-transplant inflammatory or immunological complications.
- Conditions
- Myelofibrosis, Acute Leukemia, Myelodysplastic Syndrome, Hematopoietic Stem Cell Transplant (HSCT)
- Trial name
- Cytokinegreffe (NCT07805746)
- Testing
- Blood sampling
- Volunteers
- 96 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chest Pain, Myocardial Infarction
ECG Methods for the Prompt Identification of Coronary Events
There is a clear need to develop improved tools to stratify risk in patients who seek emergency care for chest pain, one of the most common and potentially deadliest conditions encountered in acute care settings.
- Conditions
- Chest Pain, Myocardial Infarction, Myocardial Ischemia, Acute Coronary Syndrome
- Trial name
- EMPIRE (NCT04237688)
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- University of Pittsburgh
Nasopharyngeal Carcinoma
Predictor Analysis of Acute Radiation Oral Mucositis in NPC Patients Treated With IMRT/TOMO Combined Chemotherapy
Radiation induced oral mucositis which may result in reduced quality of life is commonly seen during radiotherapy, especially combined with chemotherapy. This study is a prospective, single center, and exploratory study.
- Trial name
- NCT03647527
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhejiang Cancer Hospital
Acute Coronary Syndromes
Drug Interaction Statin
This purpose of this study is to assess the effects of BMS-919373 on the single dose Pharmacokinetics (PK) of Rosuvastatin and Atorvastatin in healthy subjects.
- Trial name
- NCT02089061
- Testing
- BMS-919373, Rosuvastatin, Atorvastatin
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Isquemic Stroke, Upper Limb Weakness Due to Central Neurologic Injury
Effectiveness of m-CIMT of the Upper Limb in Acute Post-stroke Patients. (m-CIMT, Modified Constraint-induced Movement Therapy)
m-CIMT therapy is the restriction of the unaffected upper extremity in conjunction with an upper extremity specific exercise protocol to improve the functionality and use of the affected upper extremity.
- Trial name
- m-CIMT (NCT07233161)
- Testing
- m-CIMT
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Hospital Clinic of Barcelona
Chronic Myelogenous Leukemia in Blast Crisis, Lymphocytic Leukemia, B Cell, Acute
MK0457 in Patients With Leukemia (0457-003)
In this study participants with relapsed/refractory leukemia will be given MK-0457 in sequential cohorts and with varying treatment duration to determine the maximum tolerated dose (MTD) for MK-0457.
- Conditions
- Chronic Myelogenous Leukemia in Blast Crisis, Lymphocytic Leukemia, B Cell, Acute, Myelodysplastic Syndromes, Myelogenous Leukemia, Chronic
- Trial name
- NCT00111683
- Testing
- MK0457
- Volunteers
- 28 people
- Sponsor
- Merck Sharp & Dohme LLC
Acute Lung Injury, Adult Respiratory Distress Syndrome
Clinical Trial of Nebulized Hypertonic Saline to Attenuate Post-Traumatic Acute Lung Injury
This study evaluates the use of nebulized hypertonic saline (aerosolized salt water) as a preventive treatment for post-traumatic acute lung injury (ALI).
- Trial name
- NCT01667666
- Testing
- Nebulized hypertonic saline
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Denver Health and Hospital Authority
Throat Pain
The Effectiveness of Probiotics for the Therapy of Acute Pharyngotonsillitis in Adult Patients
The addition of probiotics to the routine therapy of Acute Pharyngotonsillitis in adult patients may shorten the duration, and reduce the severity of the disease.
- Trial name
- NCT01679366
- Testing
- Probiotics
- Where
- Israel
- Volunteers
- 57 people
- Sponsor
- Ziv Hospital
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