Clinical trials: Disease, Acute
Thorax Injuries, Embolism Vein
Retrospectively Analyze the Risk Factors of VTE in 5774 Patients With Thoracic Trauma From 33 Hospitals in China, and Established a Risk Prediction Model
Retrospectively analyze the risk factors of VTE in 5774 patients with thoracic trauma from 33 hospitals in China, and established a risk prediction model
- Conditions
- Thorax Injuries, Embolism Vein, Embolism, Pulmonary, Rib Fractures
- Trial name
- MCTTVTE (NCT05770232)
- Where
- China
- Volunteers
- 5,774 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Myocarditis Acute
MYTHS - MYocarditis THerapy With Steroids
This is a phase III, multi-center international, single blind randomized controlled trial to test the efficacy of pulsed intravenous (IV) methylprednisolone versus standard therapy on top of maximal support in patients with Acute…
- Trial name
- MYTHS (NCT05150704)
- Testing
- Methylprednisolone, saline solution
- Where
- 49 sites in United States, Austria and 7 more
- Volunteers
- 288 people
- Sponsor
- Niguarda Hospital
Acute Myocardial Infarction (AMI)
Artificial Intelligence Scalable Solution for ST Myocardial Infarction
The ASSIST clinical study is an observational, multicenter study to assess the performance of a cloud-based and AI-powered electrocardiogram (ECG) analysis platform, named Willem™, developed to detect Acute Myocardial Infarction…
- Trial name
- ASSIST (NCT06939738)
- Where
- 5 sites in Portugal, Spain
- Volunteers
- 489 people
- Sponsor
- Idoven 1903 S.L.
Leukemia, Myeloid, Acute, Myelodysplastic Syndromes
Nivolumab for High-Risk MDS/AML Patients After Allogeneic Stem Cell Transplant With Post-Transplant Cyclophosphamide
There are no strategies developed post-stem cell transplant (SCT) for patients who receive allogenic SCT with a significant amount of blasts prior SCT.
- Conditions
- Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Myelodysplastic Syndrome Acute Myeloid Leukemia
- Trial name
- NCT04361058
- Testing
- Nivolumab
- Where
- United States
- Sponsor
- SCRI Development Innovations, LLC
Malnutrition, Calorie, Malnutrition; Protein
The Impact of Artificial Intelligence Dietary Smartphone Application on Nutritional Status Among Cancer Patients
Multi-center prospective pilot trial study
- Conditions
- Malnutrition, Calorie, Malnutrition; Protein, Weight Change, Body
- Trial name
- NCT04643626
- Testing
- artificial intelligence dietary android mobile application
- Where
- Malaysia
- Volunteers
- 56 people
- Sponsor
- Universiti Putra Malaysia
Sudden Cardiac Arrest, Seizures
EEG in Resuscitated In-hospital Patients
In Kuopio University Hospital Department of Clinical Neurophysiology there have been designed a fast EEG electrode, that is suitable for acute emergency use.
- Trial name
- NCT02349087
- Testing
- Acute EEG with fast applicable EEG electrode
- Where
- Finland
- Volunteers
- 1 people
- Sponsor
- Kuopio University Hospital
Ischemic Stroke, Alteplase Adverse Reaction
Predictors of AIS Unfavorable Outcomes
The investigators evaluated whether the characteristics of ischemic stroke patients, door-to-needle time, and stroke risk factors were predictive variables for unfavourable outcomes.
- Trial name
- NCT06058884
- Testing
- Alteplase
- Where
- Egypt
- Volunteers
- 592 people
- Sponsor
- Kafrelsheikh University
Acute Malignant Colonic Obstruction, Colorectal Cancer
Colonic Stenting With Elective Surgery Versus Emergency Surgery in the Management of Acute Malignant Colonic Obstruction
The use of colonic stenting with elective surgery has been suggested as an alternative management for acute malignant colonic obstruction, as emergency surgery has a high risk of morbidity and mortality.
- Conditions
- Acute Malignant Colonic Obstruction, Colorectal Cancer, Colonic Obstruction
- Trial name
- NCT01997684
- Testing
- Colonic Stenting with Elective Surgery, Emergency Surgery
- Where
- 9 sites in China
- Volunteers
- 200 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Inflammation, Obesity
Effects of a PUFA-rich Diet on Acute Metabolic and Inflammatory High-Fat Meal Responses
This study evaluates whether a diet rich in poly-unsaturated fats can compensate for the negative effects of high saturated fat meals on metabolic, inflammatory, and coagulation responses.
- Trial name
- NCT02246933
- Testing
- PUFA Diet, Control Diet
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Blood Stream Infection, Gut Microbiota
Application of Nanopore Sequencing in Newly Diagnosed Acute Myeloid Leukemia Patients With Bloodstream Infection
Acute myeloid leukemia (AML) patients are prone to blood stream infection (BSI) due to bone marrow suppression, oral and gastrointestinal mucositis, endovascular tubes, and the application of a large number of broad-spectrum…
- Conditions
- Blood Stream Infection, Gut Microbiota, Acute Myeloid Leukemia
- Trial name
- NCT05016752
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Partial Thickness Wound, Pressure Ulcer
The RESPOND Registry
The RESPOND Registry is an observational study to assess the impact of PuraPly™ AM on the management of wounds in real world clinical settings; no experimental intervention is involved.
- Conditions
- Partial Thickness Wound, Pressure Ulcer, Venous Ulcer, Diabetic Ulcer
- Trial name
- RESPOND (NCT03286452)
- Testing
- PuraPly™ Antimicrobial Wound Matrix
- Where
- 15 sites in United States
- Volunteers
- 310 people
- Sponsor
- Organogenesis
Chronic Bronchitis
Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis
A study to assess the safety and efficacy of moxifloxacin compared to that of amoxicillin-clavulanic acid for the treatment of subjects with acute exacerbation of chronic bronchitis.
- Trial name
- NCT00656747
- Testing
- Avelox (Moxifloxacin, BAY12-8039), Amoxicillin clavulanic acid
- Where
- 220 sites in Andorra, Argentina and 29 more
- Volunteers
- 1,372 people
- Sponsor
- Bayer
Acute Decompensated Heart Failure
Mobile Education System to Improve Disease Knowledge, Self-efficacy and Quality of Life in Patients With Heart Failure
Heart failure (HF) is an incurable and complex disease syndrome with sophisticated disease trajectories. The guideline for HF management suggests that treatment should include adequate education to help patients have better…
- Trial name
- NCT06161649
- Testing
- accepting the operation process of automated intelligent education software system
- Where
- Taiwan
- Volunteers
- 138 people
- Sponsor
- Chang Gung Memorial Hospital
Heart Failure, Acute Kidney Injury
Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome
The overall objective of this study is to determine whether the addition of SGLT2 inhibitors to usual care in hospitalized patients with heart failure associated acute kidney injury is safe and efficacious.
- Trial name
- NCT07273838
- Testing
- Dapagliflozin 10mg Tab
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Yale University
GVHD,Acute, GVHD, Chronic
Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD)
Range of motion, antropometric measurements, quality of life questionnaire and 2 minutes walk test will be implemented as an initial assessment.
- Trial name
- NCT05401955
- Testing
- Physical exercise
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- University of Salamanca
Chronic Obstructive Pulmonary Disease
Signaling Pathway Activation After Exercise in Patients With Chronic Obstructive Pulmonary Disease
Muscle weakness and atrophy are important consequences of chronic obstructive pulmonary disease (COPD). Although resistance exercises increase strength and muscle mass in patients with COPD, the response to training appears to be…
- Trial name
- SIM (NCT01561625)
- Testing
- exercise
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
An Evaluation of Post Discharge Utilization Among Patients With an Acute Exacerbation of COPD
Patients who are hospitalized at select Carolinas Healthcare System (CHS) sites with Chronic Obstructive Pulmonary Disorder (COPD) acute exacerbation symptoms will be treated per the CHS COPD Clinical Pathway.
- Trial name
- NCT03207776
- Testing
- Usual Care, COPD Clinical Pathway
- Where
- 8 sites in United States
- Volunteers
- 4,832 people
- Sponsor
- Wake Forest University Health Sciences
Acute Coronary Syndrome
Deciphering the Salutogenic Effects of Close Relationships: Psycho-physiological Coregulation Processes and Their Outcomes in Couples Coping With Cardiovascular Disease
The established attachment theory elucidates how early human bonds bring about functional neurophysiological alterations influencing the lifelong capacity for self and co- regulation within relationships.
- Trial name
- NCT05341440
- Where
- Israel
- Volunteers
- 81 people
- Sponsor
- Bar-Ilan University, Israel
Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia
Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma
The purpose of this study is to evaluate the safety and effectiveness of CAR-T cell immunotherapy in patients with CD19 positive relapsed or refractory Leukemia and Lymphoma.
- Conditions
- Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, Follicular Lymphoma, Mantle Cell Lymphoma
- Trial name
- NCT02851589
- Testing
- PCAR-019 (anti-CD19 CAR-T cells)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Acute Myeloid Leukemia
A Phase 1B/2A Trial of Combination of ASTX727 With ASTX029 in Acute Myeloid Leukemia
To find the recommended dose of the study drugs ASTX727 and ASTX029 that can be given to patients with relapsed/refractory AML. The goal of Part 2 of the study is to learn if the dose of study drugs found in Part 1B can help to…
- Trial name
- NCT06113289
- Testing
- ASTX727, ASTX029-01
- Sponsor
- M.D. Anderson Cancer Center
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