Clinical trials: Disease, Acute
Anxiety, Pain
Validation and Pertinence of Anxiety Analogic Visual Scale in Pain Management
Screening of anxiogenic part of pain is an imperative during a medical pain consultation. The actual tools for evaluation of this specific part are complex and time consuming.
- Trial name
- ANXYDOL (NCT02690597)
- Testing
- Anxiety visual analog scale
- Where
- France
- Volunteers
- 55 people
- Sponsor
- University Hospital, Toulouse
Urinary Tract Infections, Pyelonephritis
NRX-101 for Complicated Urinary Tract Infection (UTI) Including Pyelonephritis
The goal of this clinical study is to test NRX101 in participants with complicated urinary tract infections including pyelonephritis.
- Trial name
- NCT06128213
- Testing
- NRX101 (a fixed dose combination of D-cycloserine (DCS) and lurasidone HCl (lurasidone))
- Volunteers
- 13 people
- Sponsor
- NeuroRx, Inc.
Myocardial Infarction, Acute Coronary Syndrome
Clinical and Atherosclerotic Characteristics of Patients With ACS Associated With Cocaine Use
Cocaine use has increased in our country in recent decades. It is associated with cardiovascular events and early atherosclerotic disease. Acute coronary syndrome (ACS) is one of its most frequent and serious manifestations.
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, Cocaine Use, Cocaine Abuse
- Trial name
- NCT06177860
- Where
- Argentina
- Volunteers
- 400 people
- Sponsor
- Hospital El Cruce
Coronary Artery Disease Acute Coronary Syndrome Myocardial Ischemia Plaque Characterization
The AIPLAQUE Study: An Artificial Intelligence-based Prospective Study to Analyze PLAQUE Using CCTA
This trial is a single-center, prospective, observational clinical study. All patients who have at least one coronary artery stenosis of 30%-90% in diameter ≥ 2mm confirmed by CCTA, and who are scheduled to undergo clinically…
- Trial name
- NCT05750082
- Testing
- CCTA CT-FR CAG OCT
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Harbin Medical University
Atrial Fibrillation
Performance and Safety of the Globe® Mapping and Ablation System With the GPS™ Module for the Treatment of Atrial Fibrillation
This study will evaluate the safety and acute performance of the Globe® Mapping and Ablation System with the GPS™ Module intended to conduct electroanatomic mapping and ablation treatment of subjects with atrial fibrillation (AF).
- Trial name
- GPS-CA (NCT04486924)
- Testing
- Globe Mapping and Ablation System
- Where
- 2 sites in Canada
- Volunteers
- 18 people
- Sponsor
- Kardium Inc.
Acute Ischemic Stroke, Endovascular Treatment
Endovascular Treatment and RIPC in Acute Ischemic Stroke
Endovascular treatment（ET）is an effective therapy for acute ischemic stroke(AIS) with great vessel obstruction. However, acute complications such as high postoperative perfusion injury, hemorrhagic transformation and restenosis…
- Trial name
- EnTRIPS (NCT04581759)
- Testing
- RIPC device (IPC-906X), foundational treatment
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cholelithiasis Associated With Common Bile Duct Stones
Timing of Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiography for Acute Biliary Pancreatitis
Timing of laparoscopic cholecystectomy following after endoscopic retrograde cholangiography for acute biliary pancreatitis is a controversial issue.
- Trial name
- NCT01687959
- Testing
- tissue sampling from peritoneum of the gallbladder
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Atrial Fibrillation, Atrial Flutter
Decreasing Hospital Admissions From the ED for AAFF
Acute atrial fibrillation and flutter (AAFF) is characterized by rapid heart rates with onset less than seven days. It's the most common type of palpitation treated in the Emergency Department (ED).
- Trial name
- RAFF-3 (NCT03627143)
- Testing
- KTI activities
- Where
- 12 sites in Canada
- Volunteers
- 846 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Asthma in Children
BiPAP in Pediatric Moderate to Severe Asthma Randomized Control Trial
The goal of this clinical trial is to study if starting bi-level positive airway pressure (BiPAP), a mask that gives pressure to the lungs, works well for children in the emergency department with moderate to severe asthma…
- Trial name
- NCT05848115
- Testing
- Bi-level Positive Airway Pressure
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Colorado, Denver
Acute Liver Failure, Hepatic Encephalopathy
N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure
We have completed patient enrollment in the the double blind, randomized, placebo-controlled trial of intravenous (IV) N-acetylcysteine (NAC) vs. placebo for the treatment of non-acetaminophen ALF.
- Trial name
- NCT00248625
- Testing
- N-acetylcysteine
- Where
- 20 sites in United States, Canada and 1 more
- Volunteers
- 184 people
- Sponsor
- University of Pittsburgh
Asthma, Acute Asthma
Budesonide for Emergency Treatment of Acute Wheezing in Children
The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in the emergency room.
- Trial name
- NCT00733317
- Testing
- 0.5 mg/ml budesonide nebules, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kecioren Education and Training Hospital
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)
Phase II Study of Idarubicin, Cytarabine, and Vorinostat With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)
The goal of this clinical research study is to find the highest safe dose of vorinostat that can be given in combination with idarubicin and ara-C for the treatment of AML and high-risk MDS.
- Trial name
- NCT00656617
- Testing
- Idarubicin, Cytarabine, Vorinostat
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- M.D. Anderson Cancer Center
Leukemia
Phenylbutyrate, Dexamethasone, and Sargramostim in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Colony-stimulating factors such as sargramostim may increase the number of immune cells found in bone marrow…
- Trial name
- NCT00006240
- Testing
- sargramostim, dexamethasone, oral sodium phenylbutyrate
- Where
- 4 sites in United States
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
AML, Adult
IL-6: A Marker for AML Chemo Sensitivity
Acute myeloid leukemia (AML) is a clonal malignancy that arises from the primitive hematopoietic cells within the hematopoietic system.
- Trial name
- NCT06486350
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Fujian Medical University Union Hospital
Acute Respiratory Distress Syndrome
Impact of the Transpulmonary Pressure on Right Ventricle Function in Acute Respiratory Distress Syndrome
Pulmonary distension induced by mechanical ventilation physiologically alters right ventricle pre and after-load, hence might lead to right ventricle failure.
- Trial name
- VD-SDRA (NCT04184674)
- Testing
- Pneumotachograph, Esophageal catheter, Transthoracic and / or transesophageal cardiac ultrasound
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Ischemic Stroke
Ali Pay Intelligent Navigation Applet-aided Pre-hospital Triage for Non-emergency Medical Service Patients With Acute Ischemic Stroke
According to the Bigdata Observatory platform for Stroke of China (BOSC), the proportion of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis or endovascular treatment in China is 5.64% and 1.45%…
- Trial name
- i-Path (NCT06613074)
- Testing
- Ali Pay intelligent navigation applet
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Myelodysplastic Syndromes
Infliximab in Treating Patients With Myelodysplastic Syndrome
RATIONALE: Monoclonal antibodies, such as infliximab, can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
- Trial name
- NCT00074074
- Testing
- infliximab
- Where
- 19 sites in Belgium, Czechia and 4 more
- Volunteers
- 46 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Organ Dysfunction, Organ Support
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Acute pancreatitis may cause early respiratory, cardiovascular, or renal dysfunction and may require intensive care and organ support.
- Conditions
- Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
- Trial name
- TEA-APOD (NCT07697690)
- Testing
- Thoracic Epidural Analgesia With Ropivacaine, conventional analgesia
- Volunteers
- 150 people
- Sponsor
- First People's Hospital of Chenzhou
Heart Failure
Acute Reno-Cardiac Action of Dapagliflozin In Advanced Heart Failure Patients on Heart Transplant Waiting List
Heart failure affects 1 to 2% of the adult population in developed countries, representing about 55 million people worldwide. Advanced heart failure is a condition where the heart can no longer provide sufficient cardiac output…
- Trial name
- ARCADIA-HF (NCT06868797)
- Testing
- Biological sample for the measurement of suPAR levels.
- Where
- 11 sites in France
- Volunteers
- 103 people
- Sponsor
- Central Hospital, Nancy, France
Carbon Monoxide Poisoning
Neurological Sequelae in Patients With Acute Carbon Monoxide Poisoning
The purpose of this study is to access the clinical characteristics and risk factors for neurological sequelae after acute carbon monoxide poisoning.
- Trial name
- NCT04925297
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,250 people
- Sponsor
- The First Hospital of Jilin University
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