Clinical trials: Disease Exacerbation
Chronic Obstructive Pulmonary Disease
BACE Trial Substudy 1 - PROactive Substudy
A first sub-analysis of the BACE trial will address physical activity levels in a subgroup of the intervention study with portable validated activity monitors.
- Trial name
- PROactive (NCT02205242)
- Testing
- Azithromycin, Dynaport®
- Where
- 6 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Wim Janssens
COPD Exacerbation
COPD Care Model on Clinical and Patient-Reported Outcomes
This study is the first to evaluate a unique integrated care model for COPD which uses a validated clinical frailty indicator to set care goals and guide health care in hospital and in the community.
- Trial name
- NCT03332394
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Ottawa Hospital Research Institute
Sleep Apnea, COPD Exacerbation
Impact of Continuous Positive Airway Pressure on the Occurrence of Acute Exacerbations of COPD in Patients With COPD-OSA Overlap Syndrome (CO-OS)
Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA) are both frequent respiratory diseases with estimated prevalences between 8 and 15% of the adult population.
- Conditions
- Sleep Apnea, COPD Exacerbation, Overlap Syndrome
- Trial name
- SLEEPOVEA (NCT05958563)
- Testing
- continuous positive airway pressure treatment
- Where
- 15 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Angers
Pulmonary Disease, Chronic Obstructive
Short-term Telehealth Follow up After Hospital Discharge for Chronic Obstructive Pulmonary Disease Exacerbation
The purpose of this study is to evaluate whether the introduction of a short-term telemonitoring program for chronic obstructive pulmonary disease (COPD) patients discharged from the hospital after disease exacerbation produces…
- Trial name
- RHCluster4GR (NCT01489241)
- Testing
- Telemonitoring
- Where
- Greece
- Volunteers
- 155 people
- Sponsor
- Regional Health Authority of Sterea & Thessaly
Asthma
Laminar Airflow in Severe Asthma for Exacerbation Reduction - 48 Month Follow-up.
Temperature-controlled Laminar Airflow (TLA) treatment delivered by the Airsonett treatment device is a new treatment for patients with allergic asthma.
- Trial name
- LASER-48 (NCT02813811)
- Where
- United Kingdom
- Volunteers
- 77 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Hepatitis B, Chronic
The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation
Mother-to-child transmission (MTCT) is the most common mode of perpetuating chronic hepatitis B virus (HBV) infection in endemic countries.
- Trial name
- NCT03468907
- Testing
- Telbivudine 600mg, Tenofovir disoproxil fumarate 300mg
- Volunteers
- 111 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Prevalence of OSA in Patients Hospitalized With COPD Exacerbation
Prevalence of OSA in COPD and the Clinical Impact of OSA Diagnosis and Treatment
COPD is a major cause of morbidity and mortality and is characterized by breathing impairment and related symptoms. Obstructive sleep apnea (OSA) is a highly prevalent condition that adversely affects breathing during sleep.
- Trial name
- NCT05042154
- Testing
- WatchPAT
- Volunteers
- 300 people
- Sponsor
- Atlantic Health System
Chronic Obstructive Pulmonary Disease, Respiratory Disease
A Wireless Bed Sensor for Monitoring Coughs
Aging of the population is dramatically increasing the number of hospitalized patients, with the consequent challenges of limited medical personnel and resources in hospitals.
- Trial name
- "MoniToux" (NCT03177694)
- Testing
- Wireless bed sensor
- Volunteers
- 20 people
- Sponsor
- Ligue Pulmonaire Neuchâteloise
COPD Exacerbation Acute
Airway Inflammation, Small Airways Dysfunction, and Frequency of Exacerbations in COPD
Chronic Obstructive Pulmonary Disease (COPD) is a common, preventable, and treatable disease that is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities…
- Trial name
- NCT06040931
- Testing
- Bronchoscopy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University Hospital
Multiple Sclerosis
Efficacy Study of Adrenocorticotropin Hormone to Treat Multiple Sclerosis (MS) Relapses After Sub-responding to an Initial 3 Day Course of Intravenous (IV) Methylprednisolone
The purpose of this study is to compare intramuscular (IM) ACTH (adrenocorticotropin hormone) and intravenous (IV) methylprednisolone (Solumedrol) for the treatment of an MS (Multiple Sclerosis) relapse (exacerbation) after…
- Trial name
- RECLAIM (NCT00947895)
- Testing
- Methylprednisolone, ACTH
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Neurologique Foundation, Inc.
Allergic Asthma, Thunderstorm Asthma
Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study
Thunderstorm asthma is a recurring public health emergency in South-Eastern Australia which occurs in springtime. The major identified risk factors for thunderstorm asthma is hay fever and allergy to ryegrass pollen.
- Conditions
- Allergic Asthma, Thunderstorm Asthma, Seasonal Allergic Rhinitis, Grass Pollen Allergy
- Trial name
- CARISTA (NCT07055542)
- Testing
- Observational
- Where
- 6 sites in Australia
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Chronic Obstructive Pulmonary Disease
Acute Exacerbation of COPD and Physical Activity - Preliminary Study
People with chronic obstructive pulmonary disease (COPD) are very sedentary and efforts to establish an active lifestyle are challenging because of periodic acute exacerbations of COPD that interrupt physical activity patterns…
- Trial name
- NCT01871246
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Cystic Fibrosis
OPTIMIZing Treatment for Early Pseudomonas Aeruginosa Infection in Cystic Fibrosis
The purpose of this trial is to compare the effects of treatment with tobramycin solution for inhalation (TIS) with and without azithromycin in people with cystic fibrosis (CF) age 6 months to 18 years who have early isolation of…
- Trial name
- OPTIMIZE (NCT02054156)
- Testing
- azithromycin, Tobramycin solution for inhalation
- Where
- 45 sites in United States
- Volunteers
- 221 people
- Sponsor
- Bonnie Ramsey
COPD Exacerbation Acute, Asthma Acute
Study on Acupuncture Treatment of Chronic Airway Diseases(Asthma and Chronic Obstructive Pulmonary Disease)
For patients in the acute phase of chronic airway diseases, on the basis of guideline-directed treatment, the experimental group was given acupuncture treatment, while the control group was given sham acupuncture treatment.
- Trial name
- NCT06869525
- Testing
- Acupuncture
- Volunteers
- 576 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Chronic Obstructive Pulmonary Disease
Oxygen Therapy Remote Monitoring in COPD Patients.
Background : Long-term oxygen therapy is prescribed for patients with severe COPD. The aim of oxygen therapy is to administer oxygen at a concentration level higher than that of ambient air, in order to treat or prevent the…
- Trial name
- NCT05473780
- Where
- 36 sites in France
- Volunteers
- 159 people
- Sponsor
- Vivisol
Chronic Obstructive Pulmonary Disease Exacerbation, Magnesium Sulfate
Acute Exacerbation of COPD and Nebulized Magnesium Sulphate
This study is designed to determine the effect of Nebulized Magnesium Sulphate as an add-on therapy with conventional treatment on In-hospital outcome in patients having acute exacerbation of COPD.
- Trial name
- NCT05699720
- Testing
- Nebulized Magnesium Sulphate
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- King Edward Medical University
COPD Exacerbation
Hospitalization at Home of Elderly Patients With Exacerbated COPD
Aim of the study was to evaluate the efficacy of hospital-at-home treatment compared with inpatient care in selected elderly patients with acute exacerbation of chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00369083
- Testing
- Hospital at home treatment
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Acute Cardiovascular, Pneumonia
Evaluation of Lung Doppler Signals in Patients Presenting to EMD
Historically, ultrasound has been unable to provide interpretable data from the lung parenchyma, mainly because of the high total ultrasound energy attenuation and scattering by the air in the lungs.
- Conditions
- Acute Cardiovascular, Pneumonia, Pulmonary Embolism, CHF Exacerbation
- Trial name
- NCT01961141
- Where
- Israel
- Sponsor
- Echosense Ltd.
COPD Exacerbation
Emotional-distress-based Integrated Care Programme in Patients With an Acute Exacerbation of COPD
The investigators have developed a new counseling service that focuses on the emotional distress experienced by people living with COPD.
- Trial name
- EmoD (NCT07351929)
- Testing
- EmoD Intervention
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Shortness of Breath, Asthma in Children
The Effect of Nebulized Epinephrine in Asthma Exacerbation in Pediatric Age Group With the Standard Treatment Compared to Standard Treatment Using Improvement PRAM Score as a Primary Outcome
Our study aiming to look in improvement of Pediatric Respiratory Assessment Measure (PRAM) score as a primary outcome. The secondary outcomes involving the need for second step management, need for admission and possible side…
- Conditions
- Shortness of Breath, Asthma in Children, Epinephrine Causing Adverse Effects in Therapeutic Use, Salbutamol Adverse Reaction
- Trial name
- NCT05667727
- Testing
- nebulized epinephrine, Salbutamol
- Where
- Oman
- Volunteers
- 30 people
- Sponsor
- Oman Medical Speciality Board
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.