Clinical trials: Disease Self Management
Asthma
Asthma Digital Study
The Asthma Digital Study is a virtual, two-arm, randomized, controlled trial that will investigate the impact of digital tools on asthma symptom control, exacerbation frequency, healthcare utilization, and medical expenditures in…
- Trial name
- ADS (NCT04609644)
- Testing
- Digital Tools for Asthma Self-Management
- Where
- United States
- Volunteers
- 901 people
- Sponsor
- Elevance Health
Alcohol Dependence
Safety and Pharmacodynamic Study of GET 73 in Alcohol Dependent
Examination of the effect of GET 73 on alcohol pharmacokinetics and pharmacodynamics (intoxication and sedation)and safety profile in alcohol-dependent individuals.To evaluate whether GET 73, as compared to placebo, results in…
- Trial name
- SPAD (NCT01842503)
- Testing
- GET 73, inactive ingredients capsule
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Laboratorio Farmaceutico Ct S.r.l.
Cardiovascular Abnormalities
Postoperative Canadian Oral Anticoagulation Self-management (Post-COAGS) Trial
This study will measure the efficacy and safety of an early postoperative anticoagulation self-management program, using the CoaguChek S device, in patients undergoing mechanical valve replacements.
- Trial name
- NCT00468702
- Testing
- CoaguChek S
- Where
- Canada
- Sponsor
- Hoffmann-La Roche
Diabetes Mellitus, Type 2
Digital Self-Management and Health Coaching for Type 2 Diabetes - Impact on Diabetes Clinical and Wellness Indicators
Each subject enrolled in the study will be requested to complete an intake questionnaire including diabetes quality of life questions.
- Trial name
- NCT04057248
- Testing
- Dario Blood Glucose Monitoring System, CDE
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- LabStyle Innovations Ltd.
Hypercholesterolemia
A 6-Month Consumer Behavior Study of a Self-Management System (0803-084)(COMPLETED)
The purpose of this study is to evaluate the ability of patients with intermediate risk of heart disease to appropriately use a Self-Management System.
- Trial name
- NCT00092846
- Testing
- MK0803, lovastatin, Self-Management System
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Asthma
Study of Mepolizumab Autoinjector in Asthmatics
This study is aimed to assess the correct real-world use of an autoinjector for the repeat self-administration of mepolizumab SC, so to improve subject / physician convenience and to enable repeat dose self injection themselves…
- Trial name
- NCT03099096
- Testing
- Mepolizumab
- Where
- 38 sites in United States, Australia and 5 more
- Volunteers
- 159 people
- Sponsor
- GlaxoSmithKline
Bipolar Depression, Suicidal Ideation
NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression
NMDA antagonist drugs have increasingly been demonstrated to reduce symptoms of depression and suicidal ideation. NeuroRx has developed a sequential therapy consisting of IV NRX-100 (ketamine HCL) for rapid stabilization of…
- Trial name
- SevereBD (NCT03396601)
- Testing
- Ketamine Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- NeuroRx, Inc.
Alpha-1 Antitrypsin Deficiency
Respreeza® Self-administration and Learning Program (AmAREtTI Study)
According to the Respreeza® Summary of Product Characteristics, the initial infusions must be administered under the supervision of a health professional experienced in the treatment of alpha-1 antitrypsin deficiency, although…
- Trial name
- AmAREtTI (NCT04262284)
- Where
- 11 sites in France
- Volunteers
- 15 people
- Sponsor
- CSL Behring
Knee Osteoarthritis, Hip Osteoarthritis
The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.
The study intervention provides an innovative way of making exercise training and other recommended lifestyle modifications as accessible as possible for knee and hip OA participants by introducing a home-based exercise training…
- Trial name
- PIVOT (NCT04615377)
- Testing
- Kaia hip and knee pain application, Treatment as usual
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Kaia Health Software
Opioid-use Disorder
mHealth for Patient Self-Management of Opioid Use Disorder
Twenty individuals diagnosed with opioid use disorder (OUD) will be recruited to participate in a beta test to demonstrate feasibility of using an online tool to help them better self-manage their recovery.
- Trial name
- NCT03633929
- Testing
- KIOS OUD
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Biomedical Development Corporation
Type 2 Diabetes
Evaluation of a Digital Diabetes Self-Management Education and Support Program
The goal of this study is to examine the efficacy of an integrated solution, defined as a combination of the Abbott FreeStyle Libre 14-day CGM sensor and the Omada care team's receipt of real-time, continuous glucose data from…
- Trial name
- NCT05368454
- Testing
- Online Diabetes Self-Management Education and Support (DSMES) Program, Standard of Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Omada Health, Inc.
Rett Syndrome
A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)
The primary objectives of this study are to evaluate the safety of a single intrathecal (IT) dose of TSHA-102 in females with typical Rett syndrome, to select the TSHA-102 dose with the best benefit/risk profile based on the…
- Trial name
- NCT05606614
- Testing
- TSHA-102
- Where
- 9 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- Taysha Gene Therapies, Inc.
Type 2 Diabetes
Effectiveness of an Online Self-management Intervention for Type 2 Diabetes Mellitus
This trial was designed to evaluate the effectiveness of the dialogue-based online intervention covivio, which was designed to improve diabetes self-management in patients with type 2 diabetes.
- Trial name
- OnSeT-2D (NCT05525117)
- Testing
- covivio (additional to treatment as usual), treatment as usual
- Where
- Germany
- Sponsor
- Gaia AG
Diabetes Mellitus, Type 2
Self Titration With Apidra to Reach Target Study (START)
Primary Objective: The primary objective of this study is to demonstrate non-inferiority of a patient-managed titration algorithm (including blood glucose monitoring) for the addition of a single dose of insulin glulisine at…
- Trial name
- NCT01013571
- Testing
- insulin glargine, Apidra (insulin glulisine)
- Where
- Canada
- Volunteers
- 493 people
- Sponsor
- Sanofi
Rett Syndrome
Safety and Preliminary Efficacy of TSHA-102 Gene Therapy in Pediatric Females Aged >2 to <4 Years With Rett Syndrome
The primary objectives of this study are to evaluate the safety, tolerability and preliminary efficacy of a single intrathecal (IT) dose of TSHA-102 in pediatric females with typical Rett syndrome.
- Trial name
- ASPIRE (NCT07480564)
- Testing
- TSHA-102
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Taysha Gene Therapies, Inc.
Type 2 Diabetes Mellitus
Type 2 Diabetes Patients Switched From Sulfonylurea With Metformin to Glyburide/Metformin Combination Tablet
To evaluate the efficacy and safety of type 2 diabetes patients switched from sulfonylurea co-administered with metformin to glyburide/metformin combination tablet.
- Trial name
- NCT00541437
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Genovate Biotechnology Co., Ltd.,
Asthma, Bronchial Diseases
Asthma Data Innovation Demonstration Project
Propeller Health is collaborating with the City of Louisville and other local partners to carry out a focused demonstration project that will evaluate the effectiveness of the Propeller Health approach to asthma management while…
- Conditions
- Asthma, Bronchial Diseases, Respiratory Tract Diseases, Lung Diseases, Obstructive
- Trial name
- ADID (NCT02162576)
- Testing
- Propeller Health intervention
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- David Van Sickle
Type 2 Diabetes Mellitus
One Drop Experts Program for Type 2 Diabetes Self-Management: Impact on A1c
The One Drop Experts Program for Type 2 Diabetes Self-Management Impact on A1c trial is a 12-week long, prospective, intent-to-treat study that aims to evaluate the impact of the One Drop app and Experts program on HbA1c levels…
- Trial name
- NCT02827669
- Testing
- One Drop Experts Program, One Drop Experts Program + Apple Watch
- Where
- United States
- Volunteers
- 297 people
- Sponsor
- Evidation Health
Diabetes Mellitus Self Management Education, Diabetes
Digital Health Intervention On Awareness Of Vaccination Against Influenza Among Adults With Diabetes
The study leveraged the Dario digital health platform to retrospectively analyze data from 64,904 users with diabetes assigned by the platform into three groups: Group A received previously studied monthly flu nudge messages…
- Trial name
- NCT06840236
- Testing
- Adapted Flu nudge messages, Previously studied based on RCT
- Where
- Israel
- Volunteers
- 8,431 people
- Sponsor
- LabStyle Innovations Ltd.
Generalized Myasthenia Gravis
A Phase 3, Open-label, Crossover Study to Evaluate Self-administration of Rozanolixizumab by Study Participants With Generalized Myasthenia Gravis (gMG)
The purpose of this study is to evaluate the ability of study participants with generalized Myasthenia Gravis (gMG) to successfully self-administer rozanolixizumab after training in the self-administration technique using the…
- Trial name
- NCT05681715
- Testing
- Rozanolixizumab
- Where
- 27 sites in United States, Canada and 8 more
- Volunteers
- 62 people
- Sponsor
- UCB Biopharma SRL