Clinical trials: Disease Self Management
HIV Infections
Telephone Support to Improve Adherence to Anti-HIV Medications
This study tested a system of nursing telephone support to determine if it improves adherence to antiretroviral therapy (ART) in at-risk, treatment-experienced people.
- Trial name
- NCT00988442
- Testing
- Enhanced nursing telephone support, Standard care
- Where
- 16 sites in United States
- Volunteers
- 59 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Juvenile Idiopathic Arthritis
Internet Self-Management Program With Telephone Support for Adolescents With Arthritis
This study will evaluate the feasibility of "Teens Taking Charge: Managing Arthritis On-line" intervention that will help adolescents with arthritis to better manage their disease and improve their health-related quality of life…
- Trial name
- NCT01011179
- Testing
- Teens Taking Charge, Self-Management
- Where
- 4 sites in Canada
- Volunteers
- 46 people
- Sponsor
- The Hospital for Sick Children
Inflammatory Bowel Diseases, Ulcerative Colitis
A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease
This study aims to test the feasibility, acceptability, and preliminary efficacy of a comprehensive self-management (CSM) intervention for people with inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT05651542
- Testing
- Comprehensive Self-Management Intervention, Control
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Washington
Asthma
Symptom Perception
Older asthmatics have considerably worse outcomes than younger patients with asthma. In this study, the investigators will evaluate the role of symptom perception as a key determinant of poorer outcomes and lower adherence to…
- Trial name
- NCT03646669
- Testing
- PEF Feedback, Asthma education
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
COPD, Emphysema
The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD
COPD currently afflicts 24 million US residents; the prevalence of COPD is high among Veterans. Persons with COPD have significant functional disability as a result of the disease.
- Conditions
- COPD, Emphysema, Chronic Bronchitis
- Trial name
- WEB (NCT02099799)
- Testing
- Pedometer and Website
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VA Office of Research and Development
Children With Medical Complexity
Self-management Intervention for Children With Chronic Medical Complexity: Pilot Feasibility Trial
The investigators have developed a tool to facilitate self-management for children with medical complexity (complex, multisystem chronic diseases) called MyChildCMC (My Child's Complex Medical Condition).
- Trial name
- NCT04470193
- Testing
- MyChildCMC app
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Alcohol Use Disorder
Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers
This is a double-blind, randomized, placebo-controlled, crossover design trial tested the effect of lacosamide on alcohol self-administration and craving following a priming dose of alcohol.
- Trial name
- NCT03271528
- Testing
- Lacosamide
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Boston Medical Center
Multiple Sclerosis
A Randomized Trial of Two Formal Group Programs for Multiple Sclerosis
The purpose of this study is to compare two different educational programs for people with multiple sclerosis (MS), which is a common and often disabling disease of the central nervous system.
- Trial name
- NCT01918800
- Testing
- Fatigue: Take control, MS: Take Control
- Where
- 4 sites in United States
- Volunteers
- 282 people
- Sponsor
- VA Office of Research and Development
Acute Lymphocytic Leukemia, Acute Myeloid Leukemia
Use Feasibility of the iThermonitor in Pediatrics Patients on Myelosuppresive Therapies
This is a pilot study to evaluate the use feasibility of the iThermonitor, a continuous temperature monitoring device, as a clinical support and patient self-management tool in the management of pediatrics patients on…
- Conditions
- Acute Lymphocytic Leukemia, Acute Myeloid Leukemia, Non-Hodgkin Lymphoma
- Trial name
- NCT02410252
- Testing
- iThermonitor
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Heart Failure; With Decompensation
Danger Signs in Heart Failure- Effects of Video Education
Lack of recognition of HF danger signs and lack of understanding of how to control and minimize danger signs could lead to their escalation and prompt all-cause and HF-related health care resource utilization (HCRU).
- Trial name
- NCT03657459
- Testing
- Danger Signs of Heart Failure Videos
- Where
- 8 sites in United States
- Volunteers
- 746 people
- Sponsor
- The Cleveland Clinic
Hypertension
Self-management of Blood Pressure Medication for Hypertensive Veterans
Hypertension is the most common medical problem among US Veterans. Treatment is available and effective, but control rates remain under 75%.
- Trial name
- NCT03224624
- Testing
- self-management protocol for hypertension care
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- VA Office of Research and Development
IUD Insertion
Self-Administered Lidocaine Gel for Pain Management With IUD Insertion
For intrauterine device (IUD) insertion, currently there are no standardized clinical guidelines for pain management. The investigators aim to explore whether adequate pain relief is possible through self-administered…
- Trial name
- SALUD (NCT02738203)
- Testing
- Vaginal 2% Lidocaine, Surgical Lubricant Jelly
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Stanford University
Marijuana Use, Opioid Use
Reinforcing Effects of Marijuana and Opioids
The primary goals of this study are to examine 1) marijuana modulation of oxycodone self-administration and 2) oxycodone modulation of marijuana self-administration, under controlled conditions and across a range of doses for…
- Trial name
- NCT05485012
- Testing
- Marijuana, Opioid
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Shanna Babalonis, PhD
Chronic Disease, Hypertension
Rehabilitation in Primary Care: A Project to Maximize the Health Status of Adults With Chronic Illness
The purpose of the study is to determine whether occupational therapy and physiotherapy delivered in a primary care setting to adults with chronic illness is effective in improving health.
- Conditions
- Chronic Disease, Hypertension, Back Pain, Obesity
- Trial name
- NCT00229957
- Testing
- Occupational therapy, Physiotherapy, Self-management
- Where
- Canada
- Volunteers
- 303 people
- Sponsor
- Hamilton Health Sciences Corporation
Depression, Stress, Psychological
Rural Dementia Caregiver Project
Rural caregivers face challenges of geographic isolation and lower health care access and quality. Many rural dementia caregivers experience serious health consequences due to caregiving responsibilities that can limit their…
- Conditions
- Depression, Stress, Psychological, Self Efficacy, Loneliness
- Trial name
- NCT04428112
- Testing
- Building Better Caregivers Workshop, Attention Control
- Where
- United States
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes
Mobile Diabetes Management
The Mobile Diabetes Intervention Study trial is evaluating a diabetes coaching system, using mobile phones and patient/ physician internet portals to allow patient-specific treatment and communication by their primary care…
- Trial name
- NCT01107015
- Testing
- Tailored Patient Intervention, Patient-physician intervention, Patient and PCP intervention with analyzed data
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- University of Maryland, Baltimore
Diabetes, Diabetes Distress
Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes
Veterans with diabetes may become overwhelmed with the self-management behaviors needed to maintain optimal health. Veterans may experience diabetes distress (DD), a concept distinct from depression, due the amount and frequency…
- Conditions
- Diabetes, Diabetes Distress, Self-Management, Veteran
- Trial name
- TARDIS (NCT04587336)
- Testing
- Cognitive Interview, Baseline Survey, Qualitative Interviews
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder
Increasing the Temporal Window in Individuals With Alcohol Use Disorder
Episodic future thinking (EFT) is based on the new science of prospection, which was first identified in a Science publication in 2007 and refers to pre-experiencing the future by simulation.
- Trial name
- RP1A (NCT04125238)
- Testing
- Episodic Future Thinking, Control Episodic Thinking
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Virginia Polytechnic Institute and State University
Colorectal Cancer, Bladder Cancer
Feasibility Testing of Patient Reported Outcomes - Informed Symptom Management System (PRISMS)
This is a proof-of-concept pilot randomized clinical trial to test the feasibility of the innovative Patient-Reported Outcomes-Informed Symptom Management System (PRISMS) to enhance personalized supportive care for cancer…
- Conditions
- Colorectal Cancer, Bladder Cancer, Ovarian Cancer, Cervical Cancer
- Trial name
- PRISMS (NCT04492007)
- Testing
- Patient-Reported Outcomes-Informed Symptom Management System (PRISMS)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Diabetes
Technologically Enhanced Coaching: A Program to Improve Diabetes Outcomes
Peer support programs have been demonstrated to improve glycemic control among Veterans with poor control. This program will expand on this success by putting innovative tools in the hands of Veteran diabetes patients.
- Trial name
- VA-TEC (NCT01855399)
- Testing
- Peer Coaching, Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 290 people
- Sponsor
- VA Office of Research and Development