Clinical trials: Diseases/Diagnoses
Glioblastoma Multiforme (WHO Grade IV), Anaplastic Astrocytoma (WHO Grade III)
Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy
Cure rates for patients with high grade glioma remain disappointing, in part because tumor cells are often resistant to chemotherapy, and because using higher doses of chemotherapy causes damage to normal blood cells.
- Trial name
- NCT00272870
- Testing
- 06Benzylguanine, MGMT P140K, Meltenyi CliniMacs
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pneumonia
Diagnostic Use of Lung Ultrasound for Suspected Pneumonia in Nepal
This study is designed to evaluate the use of lung ultrasound compared to chest x-ray to diagnose pneumonia in Nepal. Given the ease, portability, and relative ease of teaching ultrasound, this would be potential technology…
- Trial name
- NCT02949141
- Testing
- Lung Ultrasound, Chest X-ray, Chest Computed Tomography (CT)
- Volunteers
- 62 people
- Sponsor
- Patan Academy of Health Sciences
Anxiety
Acupuncture Treatment in Adults Undergoing Diagnostic OGD : A Double-Blind Placebo Controlled Randomized Trial
To find out how the application of acupuncture needles to the proposed acupuncture points: Heart 7 (HT 7) and Pericardium 6 (PC 6) for reducing anxiety during Esophago-gastro-duodenoscopy (EGD)
- Trial name
- NCT00449241
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Breast Cancer
DTi Diffusion Findings in Breast MRI Screening and Diagnostic
Introduction The most common breast cancer originates within the breast milk ducts, and is called ductal carcinoma. After the stage where the cancer is found only within the ducts, it invades the breast tissue beyond the ducts…
- Trial name
- NCT03158441
- Testing
- Breast MRI
- Sponsor
- Rabin Medical Center
Hodgkin Disease, Lymphoma, Non-Hodgkin
Tissue Collection for Studies of Lymph Cancer
Background: Lab studies help researchers better understand cancer biology. This information may lead to new methods for diagnosing or treating cancer.
- Conditions
- Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Lymphomatoid Granulomatosis
- Trial name
- NCT01676805
- Where
- 2 sites in United States, Jamaica
- Volunteers
- 1,295 people
- Sponsor
- National Cancer Institute (NCI)
Non-Hodgkin's Lymphoma
Doxorubicin (Doxil) Combined With Rituxan, Cyclophosphamide, Vincristine and Prednisone in Newly Diagnosed Aggressive Non-Hodgkin's Lymphomas
The current standard treatment for non-Hodgkin's lymphoma involves drugs called cyclophosphamide, doxorubicin, vincristine, prednisone and rituxan in a regimen called "R-CHOP." Using R-CHOP therapy, complete disappearance of…
- Trial name
- NCT00184002
- Testing
- Doxorubicin, Rituxan, Cyclophosphamide, Vincristine and Prednisone
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Southern California
Autism Spectrum Disorder, Siblings
Screening for Neurodevelopmental Disorders in Siblings of Children With Autism Diagnosed in Tertiary Centers
In this study, a selective and multi-stages screening for neurodevelopmental disorders (NDD) in siblings of children with a confirmed ASD is done.
- Conditions
- Autism Spectrum Disorder, Siblings, Neurodevelopmental Disorders
- Trial name
- FRATSA (NCT05512637)
- Testing
- Step 1 - Screening ; Step 2 - Clinical interview
- Where
- France
- Volunteers
- 384 people
- Sponsor
- University Hospital, Montpellier
Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection
HPV Genotyping by DR. HPV Genotyping in Vitro Diagnostic Device (IVD) Kit in Exfoliated Cells of the Uterine Cervix
High-risk type human papillomavirus (HPV) is the known etiological agent of cervical cancer. HPV testing and risk stratification by genotyping has been recognized as an effective cervical screening program.
- Conditions
- Cervical Intraepithelial Neoplasia, Human Papillomavirus Infection, HPV Infection
- Trial name
- NCT04333212
- Testing
- DR. Chip HPV genotyping IVD kit
- Where
- 4 sites in Taiwan
- Volunteers
- 1,103 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Acute Myeloid Leukemia
A Phase 2 Study of MAX-40279 Combined With Venetoclax and Azacitidine in Unfit Newly Diagnosed Acute Myeloid Leukemia
This is a prospective, multicenter, phase Ⅱ study consisting of dose escalation and ex-pansion stages in unfit newly diagnosed AML.
- Trial name
- NCT07743112
- Testing
- MAX-40279, Azacitidine, Venetoclax
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Maxinovel Pty., Ltd.
Acute Pancreatitis
The Evaluation of Pro/Antioxidative Profile and Diagnostic Parameters in the Patients With Pancreatic Disease
The study aims to assess and analyze some selected antioxidants and laboratory parameters during hospitalization of the patients with acute pancreatitis.
- Trial name
- NCT03028181
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Pneumonia, Acute Respiratory Infection
Pediatric Pneumonia Lung Ultrasound
The purpose of this study is to evaluate the impact of LUS on the diagnosis and management of childhood pneumonia in developing countries
- Trial name
- PLUS (NCT03187067)
- Testing
- Lung ultrasound
- Where
- 2 sites in Mozambique, Pakistan
- Volunteers
- 270 people
- Sponsor
- Save the Children
Deglutition Disorders
Diagnostic Accuracy of Aerodigestive Ultrasound for Predicting Swallowing Disorders
Swallowing disorders management requires an accurate recognition of implicated anatomical structures and pathways. The usual clinical assessment of swallowing disorders lacks reliability and accuracy.
- Trial name
- DARC-VADOC (NCT04800783)
- Testing
- Swallowing ultrasound
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Hopital Forcilles
Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
Amifostine in Treating Young Patients With Newly Diagnosed De Novo Myelodysplastic Syndromes
RATIONALE: Drugs used in chemotherapy, such as amifostine, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00098683
- Testing
- amifostine trihydrate
- Where
- 85 sites in United States, Australia and 2 more
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Peritonitis
Performance of Clinical and Biological Diagnostic Tests in Reference to the Recommended Tests for the Management of Fungal Peritonitis in Intensive Care
Fungal peritonitis accounts for nearly 70% of invasive candidiasis in surgical resuscitation. Their mortality is high, around 38% and their morbidity also with an increase in length of stay in intensive care, invasive ventilation…
- Trial name
- PERISCORE (NCT03973645)
- Testing
- Patient presenting peritonitis managed with fungal research during year 2016
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Central Hospital, Nancy, France
Migraine
Trans-diagnostic Cognitive-behavioral Therapy for Treatment of Migraine
Migraine headache is one of the disabling conditions that may be associated with decreased quality of life, anxiety and depression.
- Trial name
- NCT03701477
- Testing
- Trans-diagnostic cognitive-behavioral therapy, General relaxation/stress management therapeutic session
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Isfahan University of Medical Sciences
Diagnosis, Psychiatric
Learning Diagnostic Skills Online (German: Diagnostik Skills Online Lernen)
Clinical psychologists give diagnoses to their patients everyday and these diagnoses determine if and how these patients will be treated. Misdiagnoses can have severely adverse effects.
- Trial name
- DiSkO (NCT05294094)
- Testing
- blended learning, teaching format as usual
- Where
- 3 sites in Germany
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Chronic Diarrhea of Unknown Origin
Yield of Diagnostic Tests and Effects of Crofelemer for Chronic Idiopathic Diarrhea In Non-HIV Patients
The purpose of this study is to evaluate the effectiveness of the drug Crofelemer in the treatment of non-HIV patients with chronic idiopathic diarrhea; to determine the prevalence of identifiable causes of chronic diarrhea in a…
- Trial name
- NCT03898856
- Testing
- Crofelemer, Diagnostic tests for cause of chronic diarrhea
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- The University of Texas Health Science Center, Houston
Shoulder Dislocation
Associated Pathologies Following Luxatio Erecta Humeri: A Retrospective Analysis of 31 Cases and Diagnostic Algorithm
The aim of this study was to evaluate the clinical outcome of this rare injury with special emphasis on associated pathologies. Additionally, we aimed to develop an algorithm for the diagnosis of associated pathologies following…
- Trial name
- NCT02643537
- Volunteers
- 31 people
- Sponsor
- Medical University of Vienna
Drug-induced Liver Injury, Autoimmune Hepatitis
Discrimination of DILI and AIH by Artificial Intelligence
A retrospective, multi-center, non-interventional cohort study has been going to explore whether artificial intelligence can discriminate Drug-induced liver injury and Autoimmune hepatitis.
- Trial name
- NCT05532345
- Where
- China
- Volunteers
- 2,583 people
- Sponsor
- Beijing Friendship Hospital
Metastatic Colorectal Cancer, Metastatic Gastroesophageal Adenocarcinoma
Safety of Trifluridine/Tipiracil in Patients With Dihydropyrimidine Dehydrogenase Deficiency Diagnosed With Metastatic Colorectal or Gastroesophageal Cancer
The goal of this clinical trial is to test the safety of the trifluridine/tipiracil as replacement of fluoropyrimidines based chemotherapy as first line metastatic colorectal or gastroesophageal cancer regimens in patients with…
- Conditions
- Metastatic Colorectal Cancer, Metastatic Gastroesophageal Adenocarcinoma, DPD Deficiency
- Trial name
- TRIFLUOX-DP (NCT06245356)
- Testing
- Lonsurf, Oxaliplatin, Panitumumab
- Where
- 21 sites in France
- Volunteers
- 73 people
- Sponsor
- UNICANCER
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