Clinical trials: Diseases/Diagnoses
Functional Gastrointestinal Disorders
Multi-center Study on Pediatric Functional Gastrointestinal Disorders in Mainland China
This study plans to understand the prevalence and clinical characteristics of pediatric functional gastrointestinal disorders in mainland China through multi-center investigation and clinical epidemiological analysis, to reveal…
- Trial name
- NCT04388137
- Testing
- No intervention.
- Volunteers
- 1,500 people
- Sponsor
- Zhejiang University
Breast Cancer, Breast Cancer and Rehabilitation
Cancer Patient Navigation and Readiness
This study evaluated whether Cancer Patient Navigation (CPN) services could improve readiness for the transition from breast cancer diagnosis to treatment.
- Conditions
- Breast Cancer, Breast Cancer and Rehabilitation, Transition Care, Breast Cancer - Female
- Trial name
- CPN Readiness (NCT07892157)
- Testing
- Cancer Patient Navigation Services
- Where
- Indonesia
- Volunteers
- 64 people
- Sponsor
- Universitas Muhammadiyah Semarang
Cancer, Hematologic Malignancies
Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
The purpose of this study is to determine if denosumab is non-inferior to zoledronic acid in the treatment of bone disease from multiple myeloma.
- Conditions
- Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology
- Trial name
- NCT01345019
- Testing
- Denosumab, Zoledronic acid, Denosumab (for the open-label treatment phase)
- Where
- 309 sites in United States, Australia and 27 more
- Volunteers
- 1,718 people
- Sponsor
- Amgen
Vaccines, Adverse Effects, Injection Site Reaction
Evaluation of Deltoid Exercises on Injection Site Pain After (BNT162b2) COVID - 19 Vaccination
Pfizer - BioNTech (BNT162b2) COVID - 19 vaccine is the first vaccine to be approved for emergency use by FDA. The most commonly reported side effect of the BNT162b2 vaccination is mild-to-moderate pain at injection site, i.e.
- Trial name
- NCT05157230
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Peri-implant Mucositis, Peri-Implantitis
Peri-implant Phenotype, Calprotectin and Mmp-8 Levels in Cases Diagnosed With Peri-implant Disease
Following the implantation procedures; The peri-implant mucosa may begin to show signs of inflammation depending on the patient (bruxism, lack of oral hygiene) or other factors (planning errors, iatrogenic factors).
- Trial name
- NCT06173739
- Testing
- Non-surgical mechanical treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Beliz Önder
Chronic Liver Diseases, Spleen Stiffness
Clinical Trial to Evaluate the Effectiveness of Liver Shear Wave Quantization Detector Spleen Stiffness Value in the Diagnosis of Esophageal Varices
Esophageal variceal bleeding is one of the serious and life-threatening complications of chronic liver disease (CLD). Studies have shown that the prevalence of esophageal varices (EV) in patients with liver cirrhosis is about…
- Conditions
- Chronic Liver Diseases, Spleen Stiffness, Esophageal Varices, Diagnostic Performance Study
- Trial name
- NCT07753577
- Volunteers
- 246 people
- Sponsor
- Beijing Friendship Hospital
Kidney Tumor, Renal Benign Neoplasm
Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors
The goal of this clinical trial is to better tell apart whether kidney tumors are benign (not cancer) or malignant (cancer) based on a biopsy or imaging tests and ask patients how they feel about decisions they make about…
- Conditions
- Kidney Tumor, Renal Benign Neoplasm, Renal Malignant Tumor
- Trial name
- BIOPSy (NCT05728957)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Loyola University
Opioid-induced Constipation, Cancer
Study of Opioid-Induced Constipation 1 Project
The aim of the project is to investigate opioid-induced constipation (OIC) in a real world / diverse group of patients with cancer.
- Conditions
- Opioid-induced Constipation, Cancer, Cancer Pain
- Trial name
- StOIC-1 (NCT04350112)
- Testing
- Clinical assessment
- Where
- 16 sites in United Kingdom
- Volunteers
- 1,007 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Peri-implantitis, Alveolar Bone Loss
Diagnostic Accuracy of Large Language Models for Peri-Implant Marginal Bone Loss on Panoramic Radiographs
Dental implants are a routine treatment for missing teeth, but the number of implants affected by peri-implantitis, a progressive inflammatory disease of the tissues around implants, is increasing.
- Conditions
- Peri-implantitis, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07907900
- Testing
- Multimodal large language model evaluation (ChatGPT, Gemini, Claude, DeepSeek, Grok)
- Where
- Turkey (Türkiye)
- Volunteers
- 784 people, healthy volunteers welcome
- Sponsor
- Ankara University
Ovarian Cancer, Cervical Cancer
Oral Iron vs. Placebo in Newly Diagnosed Gynecologic Oncology Patients Who Are Surgical Candidates.
The prevalence of anemia in gynecologic oncology new patients has been seen in previous studies to be as high as 35-59%. this population includes women with several types of gynecologic malignancies.
- Conditions
- Ovarian Cancer, Cervical Cancer, Uterine Cancer, Anemia
- Trial name
- NCT01953107
- Testing
- Oral Ferrous Fumarate
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Sunnybrook Health Sciences Centre
To Assess the Presence of Internal Pudendal Artery Disease in Patients With Erectile Dysfunction Undergoing Coronary Angiography
Prevalence Of Internal Pudendal Artery Disease In Patients With Erectile Dysfunction Undergoing Diagnostic Coronary Angiography
Subjects in this study have recently had or are scheduled for a coronary angiography as part of their normal, routine medical care. This procedure uses x-ray imaging to see the inside of the heart's blood vessels.
- Trial name
- NCT01276145
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Chicago
Takayasu Arteritis, Behcet Disease
Turkish Adaptation of the VascuQoL-6 Quality of Life Scale
Study type: Observational study Primary objective: The aim of this study was to examine the validity and reliability of the Vascular Quality of Life Questionnaire-6 (VascuQoL-6) in Turkish in individuals diagnosed with Takayasu…
- Conditions
- Takayasu Arteritis, Behcet Disease, Quality of Life
- Trial name
- NCT06979245
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Uşak University
Acute Kidney Injury
Fractional Excretion of Urea for the Differential Diagnosis of Acute Kidney Injury in Cirrhosis
The aim of this study is to evaluate: The diagnostic performance of Fractional Excretion of Urea (FEUrea) for the differential diagnosis of acute kidney injury in patients with cirrhosis and ascites presenting to a tertiary care…
- Trial name
- NCT04986137
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Coronary Disease, Heart Diseases
Clinical Efficacy of Stent-balloon-stent (SBS) Technique in the Treatment of Coronary Bifurcation Lesions
The treatment of coronary bifurcation lesions continue to remain challenges. Due to the special hemodynamics caused by the special anatomical structure of the coronary bifurcation, it is easy to cause vascular crest displacement…
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Vascular Diseases
- Trial name
- NCT06045039
- Testing
- Stent-balloon-stent (SBS) technique
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Induction Chemotherapy, Acute T-Lymphocytic Leukemia
Study of Decitabine Combined With HAAG Regimen in Newly Diagnosed ETP-ALL/LBL, T/M-MPAL and ALL/LBL With Myeloid or Stem Cell Markers Patients
The purpose of this study is to evaluate the efficacy and safety of decitabine combined with HAAG regimen in the treatment of newly diagnosed patients with ETP-ALL/LBL, T/M-MPAL and ALL/LBL with myeloid or stem cell markers.
- Conditions
- Induction Chemotherapy, Acute T-Lymphocytic Leukemia, T-cell Lymphoblastic Lymphoma Leukemia, T-cell/Myeloid Mixed Phenotype Acute Leukemia
- Trial name
- NCT04446130
- Testing
- Decitabine combined with HAAG Regimen
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Diabetic Retinopathy, Diabetic Macular Edema
Evaluation of NeoRetina Artificial Intelligence Algorithm for the Screening of Diabetic Retinopathy at the CHUM
This prospective study aims to validate if NeoRetina, an artificial intelligence algorithm developped by DIAGNOS Inc. and trained to automatically detect the presence of diabetic retinopathy (DR) by the analysis of macula…
- Conditions
- Diabetic Retinopathy, Diabetic Macular Edema, Diabetic Maculopathy
- Trial name
- DR-NeoRetina (NCT04699864)
- Testing
- Screening of DR and DME with artificial intelligence using NeoRetina, Routine ophthalmological evaluation of DR and DME, Manual grading of DR and DME by CHUM ophthalmologists based on retinal photographies acquired by Diagnos
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Covid19, Anxiety
COVID 19 and Psychological Health: a Cross Sectional Study to Evaluate Anxiety and Depression in Covid-19 Patients
The covid-19 pandemic started to spread worldwide since December 2019. It promoted to an exaggerated psychological stress and anxiety in humans due to the intolerable symptoms higher than usual death of many infected patients.
- Conditions
- Covid19, Anxiety, Depression
- Trial name
- NCT04689464
- Where
- Iraq
- Volunteers
- 450 people
- Sponsor
- Alhasan Mujtaba Al-Mudhaffer
New-onset Type 1 Diabetes Mellitus
Study of Antithymocyte Globulin for Treatment of New-onset T1DM
Antithymocyte globulin (e.g., Thymoglobulin®) is an antibody preparation that is commonly used to treat and prevent organ transplant rejection.
- Trial name
- START (NCT00515099)
- Testing
- Antithymocyte globulin
- Where
- 9 sites in United States
- Volunteers
- 58 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Narcolepsy Type 1, Hypersomnia
A Pilot Observational Study to Assess the Ability of Continuous 'Home' EEG to Accurately Diagnose Narcolepsy and Demonstrate Response to Treatment
The goal of this pilot observational study is to assess the ability of continuous 'home' EEG to accurately diagnose Narcolepsy in children and young people with hypersomnia.
- Trial name
- NCT05983731
- Volunteers
- 60 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Lymphoma, Follicular
A Study to Evaluate the Efficacy and Safety of Golcadomide in Combination With Rituximab in Participants With Newly Diagnosed Advanced Stage Follicular Lymphoma
The purpose of this study is to assess the efficacy and safety of golcadomide in combination with rituximab in participants with newly diagnosed advanced stage Follicular Lymphoma (FL).
- Trial name
- GOLSEEK-2 (NCT06425302)
- Testing
- Golcadomide, Rituximab, Cyclophosphamide
- Where
- 56 sites in United States, Australia and 11 more
- Volunteers
- 95 people
- Sponsor
- Celgene
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