Clinical trials: Diseases/Diagnoses
Heart, Heart Failure
Kosmos PLAX EF Pivotal Study
The purpose of this study is to validate the efficacy of Kosmos PLAX EF, an AI-assisted workflow that uses a cardiac ultrasound clip in Parasternal Long Axis (PLAX) cardiac view to calculate Left Ventricular Ejection Fraction…
- Conditions
- Heart, Heart Failure, Ejection Fraction, Left Ventricular Ejection Fraction
- Trial name
- NCT07771231
- Testing
- PLAX EF Manual vs. Automatic Measurement
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- EchoNous Inc.
Attention Deficit Hyperactivity Disorder (ADHD)
The Safety and Efficacy of Terpene-enriched Cannabidiol (CBD) Oil in ADHD
ADHD is the most frequent neurodevelopmental disorder in childhood. Symptoms often appear in preschool years, and most children (65-80%) continue to experience some ADHD-associated symptoms into adolescence and adulthood.
- Trial name
- NCT06542445
- Testing
- Oral CBD oil enriched with terpenes
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Bazelet Nehushtan LtD.
Diabetes Mellitus, Type 2, Autoimmune Diabetes
Metabolic and Immunoinflammatory Profiles in Adults With Newly Diagnosed Diabetes
The goal of this observational study is to better understand how diabetes develops in adults at the time of diagnosis. The study focuses on adults with newly diagnosed diabetes in the Kazakh population.
- Trial name
- AD-HET-KZ (NCT07522502)
- Where
- Kazakhstan
- Volunteers
- 240 people
- Sponsor
- West Kazakhstan Marat Ospanov Medical University
Borderline Personality Disorder
The Short-Term MBT Project
The study will evaluate the benefitial and harmful effects of short-term (20 weeks) compared to long-term (14 months) mentalization-based therapy for outpatients with subthreshold or diagnosed borderline personality disorder.
- Trial name
- MBT-RCT (NCT03677037)
- Testing
- Short-term MBT, Long-term MBT
- Where
- Denmark
- Volunteers
- 166 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Caries, Diagnoses Disease
Evaluation of Caries Detection Methods
The investigators aim will be to compare the diagnostic performance of clinical visual examination (ICDAS II), intraoral/bite wing radiography (BW), near infrared light transillumination (NIR-LT), and laser fluorescence (LF), in…
- Trial name
- NCT05064566
- Testing
- caries assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Nazan Kocak Topbas
Tissular Lesion
Interest in Using Ultrasound Fusion in Percutaneous Interventional Radiology
The investigators want to evaluate the accuracy of an ultrasound fusion guiding system in the positioning of a needle (here the accuracy is evaluated with a 22G spinal needle), by comparing the path indicated by the ultrasound…
- Trial name
- ECHOFUSION (NCT02563444)
- Testing
- Ultrasound fusion guiding system - TUS A-500 (Aplio 500)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Strasbourg, France
Claustrophobia, Complication of Diagnostic Procedure
Reduction of Claustrophobia and Patient Motion After Training of MRI Personnel in Comfort TalkTM
Annually, an estimated 700,000 patients do not complete their scheduled MRI scans because of claustrophobia or inability to hold still.
- Trial name
- NCT01563198
- Testing
- Comfort Talk®
- Where
- 4 sites in United States
- Volunteers
- 97,712 people
- Sponsor
- Hypnalgesics, LLC
Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder)
Evaluation of the Patient Deterioration Warning System
The overall goal of the project is to reduce the number of unexpected patient deteriorations by 50% at Emergency Departments (ED) by investigating if the novel Patient Deterioration Warning Systems (PDWS), can improve clinicians'…
- Conditions
- Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder), Cardiac Arrest (Disorder), Patient Died in Hospital (Finding)
- Trial name
- PDWS (NCT03375658)
- Testing
- PDWS Intervension
- Where
- 2 sites in Denmark
- Volunteers
- 6,500 people
- Sponsor
- University of Southern Denmark
Postmenopausal Women, Stable Angina Pectoris
Coronary Artery Disease (CAD) in Postmenopausal Women
Aim of this study is the determination of a valid procedure for ischemia diagnositc in postmenopausal women.
- Trial name
- FEMCAD (NCT00763464)
- Testing
- stress-echocardiography, stress-MRI
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Hodgkin Lymphoma
Targeted BEACOPP Variants in Patients With Newly Diagnosed Advanced Classical Hodgkin Lymphoma
The Purpose of this trial is: to determine complete response rate (CRR) after six cycles of chemotherapy to determine complete remission rate (CR/CRr) as final treatment outcome after completion of treatment
- Trial name
- NCT01569204
- Testing
- Etoposide, Cyclophosphamide, Doxorubicin
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Cologne
Osteoporosis, Diagnoses Disease
Normative Database for HR-pQCT-Based Radius and Tibia Strength
A novel methodology was recently developed and validated by the applicants to compute bone strength at the distal radius and tibia using second-generation HR-pQCT reconstructions.
- Conditions
- Osteoporosis, Diagnoses Disease, Fracture, Bone Strength
- Trial name
- NODARATIS (NCT03219099)
- Where
- Switzerland
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pulmonary Tuberculoses
Phase 2 Trial to Evaluate the Safety and Tolerability and Early Bactericidal Activity of RESP30TB in Tuberculosis
A Phase 2 Trial to Evaluate the Safety and Tolerability and Early Bactericidal Activity of Nebulised RESP30TB in Adults with Newly Diagnosed, Rifampicin Susceptible Pulmonary Tuberculosis
- Trial name
- NCT07073638
- Testing
- RESP30TB, HRZE (Rifampicin, Isoniazid, Pyrazinamide, Ethambutol combination)
- Where
- South Africa
- Volunteers
- 24 people
- Sponsor
- Thirty Respiratory Limited
Human African Trypanosomiasis
Assessment of Recombinant HAT-RDT Specificity
Human African trypanosomiasis HAT, or sleeping sickness, is a tropical disease caused mainly by the parasite Trypanosoma brucei gambiense (gHAT).
- Trial name
- NCT05637632
- Where
- Democratic Republic of the Congo
- Volunteers
- 1,504 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Breast Cancer
Combination of Letrozole, Everolimus and TRC105 in Postmenopausal Women With Hormone-Receptor Positive and Her2 Negative Breast Cancer
This study will test how well a new combination of three drugs (Letrozole, Everolimus, and TRC105) is tolerated and how well it works in Stage 2 and 3 breast cancer when given prior to definitive surgery.
- Trial name
- NCT02520063
- Testing
- Letrozole, Everolimus, TRC105
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Alabama at Birmingham
Malignant Neoplasm of Lung
Single Pulmonary Nodule Investigation
A small proportion of patients with lung cancer present with a solitary pulmonary nodule (SPN). This is an important group of patients because if it is lung cancer, presentation as a SPN represents early disease, which following…
- Trial name
- SPUtNIk (NCT02013063)
- Where
- 9 sites in United Kingdom
- Volunteers
- 375 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Leukemia, Acute, Covid19
Clinical Characteristics of Patients With Leukemia and COVID-19
The purpose of this study is to describe the main clinical characteristics of patients with de novo acute lymphoblastic leukemia treated inside the third level hospitals converted to Coronavirus disease 2019 (COVID-19) attention…
- Conditions
- Leukemia, Acute, Covid19, Leukemia, Lymphoblastic
- Trial name
- NCT04745416
- Where
- 2 sites in Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital General de Mexico
Alzheimer Disease
A Study of 18F-AV-45 in Healthy Volunteers
This study will determine how florbetapir F 18 (18F-AV-45) radioactivity is distributed throughout the body.
- Trial name
- NCT01564706
- Testing
- florbetapir F 18
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Small Cell Lung Cancer
Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)
Researchers are looking for new ways to treat Limited-Stage Small Cell Lung Cancer (LS-SCLC), a type of lung cancer that has not spread from the lung to other parts of the body.
- Trial name
- NCT04624204
- Testing
- Pembrolizumab 200 mg, Pembrolizumab 400 mg, Olaparib 300 mg BID
- Where
- 187 sites in United States, Australia and 23 more
- Volunteers
- 672 people
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Efficacy Study of Diabetes Group Visits
Much evidence exists that new, more effective methods of delivering care to diabetics are necessary. In our current system of delivering care, diabetes care is often done in the context of multiple other issues addressed during a…
- Trial name
- NCT01497301
- Testing
- Group Visits
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Breast Cancer
Effects of Mindfulness Meditation and Stress Management After Breast Cancer
The primary aim of this study is to examine the effects of a mindfulness-based stress reduction training program, delivered in individual web-based sessions, among breast cancer patients.
- Trial name
- NCT02119481
- Testing
- Mindfulness-based stress reduction, Expressive writing condition
- Where
- Sweden
- Volunteers
- 142 people
- Sponsor
- Karolinska Institutet
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.