Clinical trials: Diseases of the Genitourinary System
Intrauterine Adhesions
Efficiency of Amnion Graft to Prevent Intrauterine Adhesions After Hysteroscopic Surgery
The purpose of the study is to evaluate whether human amnion graft reduces the reformation of severe intrauterine adhesions (IUA) following hysteroscopic adhesiolysis.
- Trial name
- NCT02132104
- Testing
- Uterine application of amnion membrane, Foley balloon, Femoston
- Where
- 2 sites in China
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Endometrial Neoplasms
Uterine Manipulator Versus no Uterine Manipulator in Endometrial Cancer Trial
Minimally invasive surgery is the recommended approach in endometrial cancer (EC) patients based on the results of two randomized controlled trials, given its advantages without compromised oncologic outcomes.
- Trial name
- MANEC (NCT05687084)
- Testing
- Uterine manipulator use
- Where
- 3 sites in Italy
- Volunteers
- 1,030 people
- Sponsor
- Universita di Verona
Bladder Cancer
Chemoradiotherapy for Recurrent T1G3 Bladder Cancer
To evaluate the short term results of chemoradiation in case of T1G3 BC after BCG failure.
- Trial name
- NCT03274284
- Testing
- chemoradiation
- Volunteers
- 20 people
- Sponsor
- Assiut University
Carcinoma in Situ, Non Muscle Invasive Bladder Cancer
Study With TMX-101 in Patients With Carcinoma In Situ (CIS) Bladder Cancer
This is a Phase II pilot study to explore the effect of intravesical TMX-101 in patients with CIS bladder cancer, as assessed by histology and cytology after TMX-101 treatment.
- Trial name
- NCT01731652
- Testing
- TMX-101
- Where
- 4 sites in United States
- Volunteers
- 12 people
- Sponsor
- Telormedix SA
Post Partum Hemorrhage
Mansoura-VV Uterine Compression Suture for Primary Atonic Postpartum Hemorrhage
Postpartum hemorrhage is the leading cause of maternal, uterine atony accounts for 75-90% of primary postpartum hemorrhage. The efficacy of the Uterine compression suture in the treatment of atonic postpartum hemorrhage is…
- Trial name
- NCT03117647
- Testing
- Mansoura-VV compression suture
- Volunteers
- 108 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia
Is Ejaculation Preservation TURis the Natural Evolution of the "Gold Standard".
evaluation of the impact of apical urethral mucosa sparring with the urethra around the verumontanum on the ejaculatory function and early postoperative urinary incontinence
- Trial name
- NCT06263049
- Testing
- transurethral resection of prostate
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Brain and Central Nervous System Tumors, Childhood Langerhans Cell Histiocytosis
Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other sources to damage tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
- Conditions
- Brain and Central Nervous System Tumors, Childhood Langerhans Cell Histiocytosis, Gastrointestinal Carcinoid Tumor, Head and Neck Cancer
- Trial name
- NCT00002947
- Testing
- indium In 111 pentetreotide
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Yale University
End Stage Renal Disease
Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD
Prospective, randomized, controlled clinical trial. The aim is to compare the effects of the peritoneal dialysis solution IPX15, containing glucose (0.5%), xylitol (1.5%) and L-carnitine (0.02%) as osmotic agents (comparable to…
- Trial name
- NCT04001036
- Testing
- 1.5% Xylitol, 0.5% Glucose, and 0.02% L-carnitine, 0.7% Xylitol, 0.5% Glucose, and 0.02% L-carnitine
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- Iperboreal Pharma Srl
Prostate Cancer
5 Fractions of Pelvic SABR With Intra Prostatic SABR
Stereotactic Ablative Radiation(SABR) 35 Gy in 5 fractions, once weekly to prostate with simultaneous intraprostatic boost to the MR detected nodule up to 50Gy + 25 Gy in 5 fractions, once weekly simultaneously to seminal…
- Trial name
- 5STAR (NCT02911636)
- Testing
- Pelvic SABR with intra-prostatic SABR
- Volunteers
- 30 people
- Sponsor
- Andrew Loblaw
Prostate Cancer
Hemiablative Focal Brachytherapy Pilot Study
Whole gland LDR brachytherapy has been a well established modality of treating low risk prostate cancer. Treatment in a focal manner has the advantages of reduced toxicity to surrounding organs.
- Trial name
- NCT02643511
- Testing
- Transperineal template guided mapping biopsy, multiparametric MRI, Hemiablative Focal Brachytherapy
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St George Hospital, Australia
Apical Periodontitis, Chronic Kidney Diseases
Effects of RCT on Periapical Healing, Inflammatory Markers, and Kidney Function Indicators in CKD Patients With AP
The purpose of this prospective study is to determine the effect of non-surgical root canal treatment in chronic kidney disease patients and healthy patients with apical periodontitis.
- Trial name
- NCT06446011
- Testing
- root canal treatment in Ckd patients, root canal treatment in healthy patients
- Where
- India
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Diabetes, Diabetic Kidney Disease
Effect of Acute Hypoxia on Renal Hemodynamic in Healthy Volunteers, Patients With Diabetes and Patients With Diabetes and Kidney Disease
Diabetes mellitus is a non-transmissible disease whose incidence is growing worldwide . This pathology is defined by a chronic hyperglycaemia linked to a deficiency of either insulin secretion or its action or both.
- Conditions
- Diabetes, Diabetic Kidney Disease, Hypoxia, Healthy Volunteer
- Trial name
- DIAKIPOX (NCT06846034)
- Testing
- Hypoxia administration study group, Renal clairance study
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Pre-Eclampsia
Autogenic Training Effects on Pre-eclampsia
The purpose of study is to find the effects of autogenic training on blood pressure and anxiety in preeclampsia females. There is little of evidence to allow conclusions about effectiveness of autogenic training on preeclampsia…
- Trial name
- NCT05709834
- Testing
- Autogenic training, Conventional treatment
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
HIV Infections
Evaluating the Safety and Efficacy of Long-Acting Injectable Cabotegravir Compared to Daily Oral TDF/FTC for Pre-Exposure Prophylaxis in HIV-Uninfected Women
This study will evaluate the safety and efficacy of the long-acting injectable agent cabotegravir (CAB LA) compared to daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) for pre-exposure prophylaxis (PrEP) in…
- Trial name
- NCT03164564
- Testing
- Oral CAB, Oral TDF/FTC, CAB LA
- Where
- 20 sites in Botswana, Eswatini and 5 more
- Volunteers
- 3,224 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Type 2 Diabetes Mellitus
A Clinical Study to Evaluate Renal Hemodynamic Responses to Aliskiren in Patients With Type 2 Diabetes Mellitus
The study objective was to assess the effect of single and multiple doses of aliskiren on renal plasma flow, glomerular filtration rate and to compare the effects of single and multiple doses of aliskiren versus captopril or…
- Trial name
- NCT00660309
- Testing
- Aliskiren, Irbesartan, Captopril
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Novartis
Kidney Disease, Kidney Failure
A Retrospective Multicenter Study to Determine 5-Year Clinical Outcomes in Subjects Previously Enrolled in the CTOT-01 Study
This study is a multicenter, non-randomized, retrospective study to collect long term (5 years post-transplant) clinical outcome data to test whether the results of the noninvasive immune monitoring test strategy performed in the…
- Conditions
- Kidney Disease, Kidney Failure, End Stage Renal Disease
- Trial name
- NCT01974999
- Where
- 7 sites in United States, Canada
- Volunteers
- 184 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
POPQ Associated With Total Laparoscopic Hysterectomy
The goal of this observational study is to evaluate the impact of different hysterectomy (removal of the uterus) techniques on the risk of pelvic organ prolapse (situation when one or more of your pelvic organs like your bladder…
- Conditions
- Uterine Fibroids (UF), Abnormal Uterine Bleeding Unrelated to Menstrual Cycle, Endometrial Hyperplasia, Pelvic Organ Prolapse (POP)
- Trial name
- POP-LAP (NCT07137299)
- Testing
- Questionnaire and Physical Exam
- Where
- 4 sites in Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Silesia
Premature Birth
Family Integrated Care (FICare) in Level II NICUs
In Alberta, nearly one in every twelve babies is born too soon (preterm). Preterm babies are at greater risk for breathing and feeding problems, as well as infections, than babies born on their due date (full term).
- Trial name
- FICare (NCT02879799)
- Testing
- Implement Family Integrated Care
- Where
- 10 sites in Canada
- Volunteers
- 765 people
- Sponsor
- University of Calgary
Schistosomiasis Haematobia
The Chinese-made Praziquantel for Treatment of Schistosoma Haematobium
Schistosomiasis remains an important parasitic disease in the tropics, special in Africa including Zanzibar. The WHO-recommended strategy to eliminate schistosomiasis involves large-scale treatment of affected populations through…
- Trial name
- NCT03133832
- Testing
- Companion Tablet
- Where
- Tanzania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jiangsu Institute of Parasitic Diseases
Fetal Growth Restriction, Small for Gestational Age at Delivery
Evaluation of HALP Score in Distinction Between FGR and SGA
Fetal Growth Restriction (FGR) and Small for Gestational Age (SGA) are two conditions that can happen when a baby doesn't grow as much as expected during pregnancy.
- Trial name
- NCT05814198
- Testing
- HALP score
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
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