Clinical trials: Diseases of the Genitourinary System
Endometriosis
The Developmental Origins of Endometriosis
Introduction: Endometriosis is a common pathology affecting one in 10 women, characterized by the ectopic development of endometrium, which can cause pain and/or infertility.
- Trial name
- ENDOHaD (NCT05951452)
- Testing
- Blood samples for testosterone and SHBG measurements, Saliva samples for oxytocin measurements
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Montpellier
Prostate Adenocarcinoma, Stage IIB Prostate Cancer AJCC v7
68Ga-PSMA-11 PET/CT in Imaging Patients With Intermediate or High Risk Prostate Cancer Before Surgery
This clinical trial studies how well 68Ga-PSMA-11 positron emission tomography (PET)/computed tomography (CT) works in imaging patients with intermediate or high risk prostate cancer before surgery.
- Conditions
- Prostate Adenocarcinoma, Stage IIB Prostate Cancer AJCC v7, Stage III Prostate Cancer AJCC v7, Stage IV Prostate Cancer AJCC v7
- Trial name
- NCT03368547
- Testing
- Computed Tomography, Gallium Ga 68 Gozetotide, Positron Emission Tomography
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Vaginal Candidiasis
Use of Oral Probiotics as an Adjunctive Therapy to Fluconazole in the Treatment of Yeast Vaginitis
Yeast vaginitis is a very common ailment affecting premenopausal women in Nigeria. This condition is more prevalent in the age group between 21-30 years.
- Trial name
- NCT00479947
- Testing
- Probiotics (Natural product), Probiotics (L. rhamnosus GR-1 and L. reuteri RC-14)
- Where
- Nigeria
- Volunteers
- 100 people
- Sponsor
- Faith Mediplex
Incontinence
Efficacy of Functional Magnetic Stimulation in Urinary Incontinence
Functional Magnetic Stimulation (FMS) appears to modulate autonomic and somatic nervous systems that innervate the lower urinary tract.
- Trial name
- FMS (NCT02091947)
- Testing
- FMS (Magstim rapid2)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- vghtpe user
HIV Infections
Double Blind Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected Patients
Examine the ability of Timunox (thymopentin) to reduce the amount and/or frequency of virus isolation. Examine the ability of thymopentin to stimulate the immune system and alter the clinical findings of patients infected with…
- Trial name
- NCT00002049
- Testing
- Thymopentin
- Where
- United States
- Sponsor
- Immunobiology Research Institute
Endometriosis, Chronic Pain
Therapeutic-educational Physiotherapy on Pain, Physical-functionality and Quality of Life in Women With Endometriosis.
This is a randomized clinical trial that will be carried out in women with endometriosis divided into two groups: the experimental group (EG) that will receive therapeutic-educational physiotherapy, which will combine therapeutic…
- Conditions
- Endometriosis, Chronic Pain, Women's Health
- Trial name
- PHYSIO_ENDOM (NCT06212349)
- Testing
- therapeutic-educational physiotherapy and pain education program, pain education program
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- University of Valencia
Chronic Kidney Diseases, Dialysis
Dialysis Geriatric Care Model
The objectives of this study are to refine the dialysis care model with key stakeholder input and conduct a pilot randomized controlled trial (RCT) to obtain evidence critical to inform a definitive RCT.
- Conditions
- Chronic Kidney Diseases, Dialysis, Geriatric
- Trial name
- NCT05793138
- Testing
- Geriatric Care Model, Usual Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Duke University
HIV Infections
Phase III Randomized Double-Blind Placebo Controlled Study To Evaluate the Safety and Efficacy of Betaseron in AIDS and Advanced ARC Patients Receiving a Reduced-Dose AZT Regimen
To evaluate the safety and efficacy of interferon beta (Betaseron) in AIDS and advanced AIDS related complex (ARC) patients receiving a reduced-dose zidovudine (AZT) regimen.
- Trial name
- NCT00002238
- Testing
- Interferon beta-1b, Zidovudine
- Where
- 25 sites in United States
- Sponsor
- Bayer
Acute Renal Failure
Early Renal Replacement Therapy and the Outcome of Acute Kidney Injury
This research project is a prospective study to compare mortality between early renal replacement therapy (RRT) and late renal replacement therapy by using plasma neutrophil gelatinase associated lipocalin (pNGAL) as a tool in…
- Trial name
- EarlyRRT (NCT01819038)
- Testing
- continuous renal replacement therapy
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chulalongkorn University
Acute Kidney Injury
Effects of BRS and LRS on Postoperative Acute Kidney Injury
1. Title: Effects of Sodium Bicarbonate Ringer's Injection and Sodium Lactated Ringer's Injection on postoperative acute kidney injury in patients undergoing major abdominal surgery: a randomized, controlled, open-label clinical…
- Trial name
- BRS/LRS (NCT04835038)
- Testing
- Sodium Bicarbonate Ringer's Injection, Sodium Lactated Ringer's Injection
- Where
- China
- Volunteers
- 3,400 people
- Sponsor
- Tongji Hospital
Human Papilloma Virus Infection
Detection of High-Risk HPV in Urine and Cervical Swab Specimen Using HPV Diagnostic Kit (Bio Farma)
This study is a cross-sectional study to evaluate accuracy of high-risk DNA-HPV testing using HPV Diagnostic Kit (Bio Farma) compared to Standard Kit (COBAS® 6800 HPV from Roche Molecular Systems) RT-PCR based in urine and…
- Trial name
- NCT06111911
- Testing
- HPV Diagnostic Kit (Bio Farma)
- Where
- Indonesia
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Gestational Diabetes Mellitus
Structured Aerobic and Resistance Exercise and Gestational Diabetes
Gestational diabetes mellitus (GDM) is defined as impaired glucose tolerance of various degrees first manifested during pregnancy. The primary aim of treating GDM is to optimize glycaemic control and improve pregnancy outcomes.
- Trial name
- NCT02196571
- Testing
- Structured Exercise
- Where
- Croatia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Association for Functional Rehabilitation, Recreation and Applied Kinesiology Impulse
Prostate Cancer
Radiation Therapy and IRreversible Electroporation for Intermediate Risk Prostate Cancer (RTIRE)
This is a single-site trial for 42 subjects with intermediate risk prostate cancer who undergo Irreversible Electroporation (IRE) followed by Magnetic Resonance guided Radiotherapy MRgRT.
- Trial name
- RTIRE (NCT05345444)
- Testing
- IRE & MRgRT
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Kidney Disease Stage 5, Chronic Kidney Disease Stage 4B
Prognostic Value of a Multidimensional Assessment for Survival in Elderly Patients With CKD 4B/5
The aim of this study is to determine a multidimensional signature (integrating frailty and patient-reported outcomes measures (PROMs) at entry into stage 4B/5 CKD) to improve prediction of renal death (dialysis, transplantation…
- Trial name
- PROFILER (NCT06825234)
- Where
- 2 sites in France
- Volunteers
- 390 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Preeclampsia, Hypertension in Pregnancy
Preeclampsia Postpartum Antihypertensive Treatment
The goal of this study is to compare whether antihypertensive treatment in the postpartum period decreases postpartum hypertension and its associated maternal morbidity, including risk of readmission and healthcare utilization in…
- Trial name
- P-PAT (NCT04298034)
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Medical College of Wisconsin
Insulin Resistance
Novel Therapy for Glucose Intolerance in HIV Disease
This research is to investigate the nutritional supplement chromium picolinate. The investigators are testing to see how effective this supplement is in treating insulin resistance associated with HIV disease.
- Trial name
- NCT02006914
- Testing
- Chromium Picolinate
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Stony Brook University
Breast Cancer, Bladder Cancer
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients
The basic premise of this research proposal is to determine whether there is any significant association between germline polymorphisms and cancers of colon, bladder, breast, testicular, prostate, ovaries, kidney, lung, lymphoid…
- Conditions
- Breast Cancer, Bladder Cancer, Kidney Cancer, Colon Cancer
- Trial name
- NCT00579514
- Testing
- PCR/PCR/LDR Strategy
- Where
- United States
- Volunteers
- 21,081 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Urolithiasis
Single-use Digital Flexible Ureteroscope vs Nondisposable Fiber Optic vs Digital Ureteroscope
The aim of this trial is to compare the safety, efficacy and cost effectiveness of the three types of scopes.
- Trial name
- NCT03220516
- Testing
- single use digital ureteroscope, reusable fiberoptic ureteroscope, reusable digital flexible ureteroscope
- Volunteers
- 450 people
- Sponsor
- Guohua Zeng
Prostatic Neoplasms, Prostatic Cancer
Treatment of Castration Resistant Prostate Cancer Using Multi-Targeted Recombinant Ad5 PSA/MUC1/Brachyury Based Immunotherapy Vaccines
Background: Metastatic castration resistant prostate cancer (mCRPC) keeps growing even when the amount of testosterone in the body is reduced to very low levels. mCRPC is incurable.
- Trial name
- NCT03481816
- Testing
- ETBX-071; adenoviral PSA vaccine, ETBX-061; adenoviral MUC1 vaccine, ETBX-051; adenoviral brachyury vaccine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Cancer Institute (NCI)
Diabetic Nephropathy
Clinical Trial Technology Development for the Validation of Surrogate Prognostic Markers in Patients With Diabetic Nephropathy
Worldwide, the most common cause of chronic kidney disease (CKD) and end stage renal disease (ESRD) is diabetes. Unlike the past, in south korea, diabetes account for more than 40% of ESRD.
- Trial name
- NCT01673204
- Testing
- Calcitriol
- Where
- 2 sites in South Korea
- Volunteers
- 276 people
- Sponsor
- Seoul National University Hospital
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