Clinical trials: Diseases of the Nervous System
Tension-Type Headache, Cervicogenic Headache
The Classification and Treatment of Myofascial Headache: a Cross-sectional Study and Randomized Controlled Trial.
This project comprises two studies; a cross-sectional study and a randomized controlled trial. 1. The goal of the cross-sectional study is to compare multiple outcome parameters in different headache types: tension type (TTH)…
- Conditions
- Tension-Type Headache, Cervicogenic Headache, Myofascial Headache
- Trial name
- COMPHAS_RCT (NCT06100588)
- Testing
- Dry Needling, Manual therapy
- Where
- Belgium
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University Ghent
Pain, Neuropathic, Neuropathic Pain
Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects
This study is being conducted to assess the effects of GSK1014802 and a positive control, lidocaine, on tests of peripheral nerve excitability. This will be a double blind, placebo controlled, 4-period cross over study.
- Trial name
- NCT00964288
- Testing
- GSK1014802 low dose, Lidocaine, GSK1014802 high dose
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Biogen
Diplegic Cerebral Palsy
"Immediate Effect of DAFO on Gross Motor Function and Balance in Diplegic Cerebral Palsy
" Study will investigate the immediate effect of DAFO usage on balance and gross motor functions in individuals with spastic diplegic cerebral palsy.
- Trial name
- NCT06343688
- Testing
- "Assessment of Balance and Lower Extremity Gross Motor Function with and without DAFO"
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Lumbar Spondylosis
Correlation Between Radiculopathy And Quality Of Life In Patients With Chronic Lumbar Spondylosis
This study will be conducted to answer the following question: Is there a Correlation Between Lumbar Radiculopathy and Quality of Life in Patients with chronic lumbar spondylosis?
- Trial name
- LS (NCT06720103)
- Volunteers
- 132 people
- Sponsor
- Cairo University
Hepatolenticular Degeneration; Wilson
Performance and Safety of MEX-CD1 Low-volume Continuous Veno-venous Haemodialysis Medical Device for Copper-extraction in Patients With Wilson's Disease
The goal of this clinical trial is to test the MEX-CD1 hemodialysis medical device in patients suffering from Wilson's Disease. The main questions it aims to answer are: Does the device work as expected by removing the excess of…
- Trial name
- MEXWILS (NCT05917327)
- Testing
- Low-volume continuous veno-venous haemodialysis
- Where
- 4 sites in France, Spain
- Volunteers
- 1 people
- Sponsor
- Mexbrain
Intracranial Aneurysms
Evaluation of DeltaMaxx® Microcoil System in Intracranial Aneurysms
The primary objective of this registry is to assess the safety and angiographic outcomes of endovascular treatment of intracranial aneurysms using the DeltaMaxx Microcoil System.
- Trial name
- NCT01945827
- Testing
- DeltaMaxx Microcoil System
- Sponsor
- Codman & Shurtleff
Knee Osteoarthritis
Evaluation of the Evolution of Biological and Imaging Markers of Bone and Cartilage Degradation in Patients With Knee Osteoarthritis Receiving Intra-articular Injections of a Hyaluronan Derivative HYMOVIS®
This pilot study MOKHA is aimed to evaluate the beneficial effect of HYMOVIS® on cartilage of patients suffering of knee osteoarthritis as revealed by using scientifically sound, objective measurements of biological and MRI-based…
- Trial name
- MOKHA (NCT04293861)
- Testing
- HYMOVIS
- Where
- 8 sites in Belgium, France
- Volunteers
- 50 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Angina (Stable), Coronary Microvascular Disease
Coronary Sinus Reducer in Coronary Microvascular Disease
Coronary microvascular dysfunction (CMD) is a common cause of treatment- resistant angina that lacks evidence-based treatment options.
- Trial name
- REDUCE CMD (NCT06898541)
- Testing
- Coronary sinus reducer
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- UMC Utrecht
Frozen Shoulder, Pain
The Effect of Breathing Exercises in Addition to Conventional Treatment in Frozen Shoulder Patients
The study aimed to investigate the effect of breathing exercises in addition to conventional treatment on pain, normal joint movement and quality of life in patients with frozen shoulder.
- Conditions
- Frozen Shoulder, Pain, Quality of Life
- Trial name
- NCT06157554
- Testing
- Breathing Exercises, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bandırma Onyedi Eylül University
Insomnia Disorder
Investigating Racing Thoughts in Patients With Insomnia Disorder
Cognitive arousal has been identified as playing a key role in the inability to fall asleep or stay asleep. However, although people with insomnia frequently complain about racing thoughts appearing as soon as they get into bed…
- Trial name
- TIP (NCT04752254)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Migraine Disorders
Non-invasive Vagus Nerve Stimulation for the Prevention of Migraines
The purpose of the study is to investigate if the use of gammaCore Sapphire™ device reduces the number of migraines preventatively.
- Trial name
- NCT03716505
- Testing
- gammaCore Sapphire active
- Where
- 30 sites in United States
- Volunteers
- 231 people
- Sponsor
- ElectroCore INC
Crohn's Disease, Inflammatory Bowel Disease
GI Symptoms and Sleep Disturbances in Patients With Quiescent Crohns Disease
In this study we would like to clarify the effect of long lasting Crohn's Disease on motility of the gastrointestinal system in patient and the effect regarding sleep disturbances.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Sleep Disturbances
- Trial name
- NCT02245594
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Acute Ischemic Stroke
NeVa ONE Registry Study
A prospective, open label study designed to assess the safety, performance and efficacy of thrombus removal in subjects presenting with acute ischemic stroke with the NeVa stent retrievers.
- Trial name
- NCT04562194
- Testing
- NeVa Stent Retriever
- Where
- 3 sites in Argentina, Italy and 1 more
- Volunteers
- 600 people
- Sponsor
- Vesalio
Stroke
Very Intensive Variable Repetitive AmbulatioN Training
The overall objective of this subproject is to evaluate the individual and paired contributions of intensity and variability of stepping training on lower extremity (LE) function, health and community participation in patients…
- Trial name
- VIVRANT (NCT02507466)
- Testing
- exercise
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Shirley Ryan AbilityLab
Tension-Type Headache
Prophylactic Effect of Memantine in Chronic Tension-Type Headache
The purpose of this study is to test whether memantine has a prophylactic effect on chronic tension-type headaches.
- Trial name
- NCT00315666
- Testing
- memantine
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Danish Headache Center
Brain and Central Nervous System Tumors, Prostate Cancer
Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer
RATIONALE: Everolimus may stop the growth of tumor cells by stopping blood flow to the tumor. Gefitinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.
- Trial name
- NCT00085566
- Testing
- everolimus, gefitinib
- Where
- 2 sites in United States, Spain
- Volunteers
- 61 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Parkinson Disease, Accidental Falls
Home-Based Exercise Program After Community Balance Training for Parkinson's Disease
This study tested whether a home-based exercise program helps older adults with Parkinson's disease keep the improvements they gain from a community balance program.
- Conditions
- Parkinson Disease, Accidental Falls, Postural Balance
- Trial name
- NCT07859566
- Testing
- Home-based exercise program with remote checking and coaching, General wellness guidance
- Where
- 4 sites in United States
- Volunteers
- 31 people
- Sponsor
- Oklahoma State University
Shotblocker, Injection Pain Prevention
The Effect of SHOTBLOCKER
This study was conducted as a randomized controlled experimental cross over study to examine the effect of injection pain, anxiety and comfort level with the use of Shotblocker in geriatric patients undergoing subcutaneous…
- Conditions
- Shotblocker, Injection Pain Prevention, Pain, Anxiety
- Trial name
- SHOTBLOCKER (NCT06956066)
- Testing
- shotblocker
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul Medeniyet University
Sleep Apnea Syndromes, Sepsis
Impact of Sleep Apnea on Sepsis Mortality
By clinical record review, this retrospective study aims to compare the mortality of sepsis patients with versus without obstructive sleep apnea, who were diagnosed and treated in Taipei Veterans General Hospital, Taiwan.
- Conditions
- Sleep Apnea Syndromes, Sepsis, Mortality
- Trial name
- NCT03654456
- Testing
- OSA
- Where
- Taiwan
- Volunteers
- 280 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
TBI (Traumatic Brain Injury)
Brain Development in Young Children Following Mild Traumatic Brain Injury - Pilot Study
Concussions (also known as mild traumatic brain injury) are common in young children. In some children, they can lead to short- and long-term difficulties.
- Trial name
- KAOUENN (NCT06024122)
- Testing
- IRM exam
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
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