Clinical trials: Disinfection
Candidiasis, Oral
Evaluation of the Effect of Different Cleaning and Disinfection Procedures on the Involvement of Candida Species
Individuals may experience tooth loss as a result of trauma, periodontal destruction, lack of adequate bone support and clinically dental mobility.
- Trial name
- NCT03894839
- Testing
- glutaraldehyde disinfection and microwave application, Chlorhexidine gluconate disinfection and microwave application, Sodium hypochlorite disinfection and microwave application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Hand Disinfection
The Impact of Patient Motivational Dialogue (PMD) on Patient Self-advocacy for Hand Hygiene
This exploratory cross sectional cohort study will evaluate the feasibility and fidelity of using an innovative strategy, the Patient Motivational Dialogue (PMD)/PMDPlus that will intentionally motivate and encourage the patient…
- Trial name
- NCT04360057
- Testing
- PMD, PMDPlus
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Dental Caries, Infection, Bacterial
Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth.
The process of removing bacteria and their products from the root canals is an essential step that is achieved through the combination of mechanical preparation and irrigation with chemicals.
- Conditions
- Dental Caries, Infection, Bacterial, Tooth, Deciduous
- Trial name
- NCT05361278
- Testing
- Chlorhexidine solution, Activated chlorhexidine solution, Chlorhexidine gel
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Damascus University
Pulp Necrosis
Photo-Activated Disinfection Versus Triple-Antibiotic Paste for Management of Necrotic Young Permanent Anterior Teeth
This study aims to compare regenerative endodontics for necrotic young permanent anterior teeth using oral photo-activated disinfection versus triple antibiotic paste in terms of: 1.
- Trial name
- NCT03763110
- Testing
- Photo Activated Disinfection, antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Aerosol Disease, Caries,Dental
Quantitative Evaluation of Aerosols Produced in the Dental Office
Background: Maintaining biosafety in dental practice requires an efficient elimination of aerosols produced during dental treatment.
- Trial name
- NCT05988359
- Testing
- Caries treatment with a dental turbine, Caries treatment with Er:YAG laser
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Shoulder Surgery
Does the Disinfection of the Subcutaneous Tissue Reduce the Contamination of the Operative Field by P. Acnes During Primary Shoulder Surgery?
Propionibacterium acnes is a pathogen frequently identified during postoperative infections of the shoulder. A recent study has shown that P.
- Trial name
- NCT03664284
- Testing
- subcutaneous disinfection
- Where
- Switzerland
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hôpital du Valais
Chronic Periodontitis
Efficacy of INERSAN in Patients With Chronic Periodontitis as Adjunctive to Full Mouth Disinfection
The purpose of this study is to evaluate beneficial effects of probiotic Lactobacillus brevis CD2 tablets in addition to the primary treatment for patients with chronic periodontitis (Full Mouth Disinfection), at local level and…
- Trial name
- NCT01438333
- Testing
- lactobacillus brevis tablets
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of L'Aquila
Surgical Wound Infection
Recolonization Following Preoperative Disinfection Plastic Adhesive Drapes
The purpose of this study is to measure the time to recolonization intraoperatively after preoperative disinfection with chlorhexidine solution in ethanol and to determine evidence of differential bacterial growth with or without…
- Trial name
- NCT01316588
- Testing
- Plastic adesive drape, Microbial Sealant
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Örebro University, Sweden
Apical Periodontitis, Pulp Disease, Dental
A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment
The goal of this observational is study is to develop a protocol for root canal biofilms disinfection using a clinically approved and commercially available iron oxide nanoparticle formulation Ferumoxytol/H2O2 treatments.
- Trial name
- NCT06110494
- Testing
- Iron oxide nanoparticles treatment Ferumoxytol/H2O2, NaOCl, NaCl
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Patients With Deep Carious Lesions
Clinical Evaluation and Microbiological Assessment of Diode Laser and Chemical Disinfection in Comparison to Selective Caries Removal
Objectives: To evaluate the clinical and antimicrobial effect of Diode laser and chemical disinfection in comparison to selective caries removal in management of deep carious lesions.
- Trial name
- NCT03955341
- Testing
- Diode laser disinfection, Chemical disinfection using 2% Chlorhexidine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Diarrhea
Health Impact Study of Aquatabs in Tamale, Ghana
The purpose of this study to determine whether Aquatabs, a water treatment tablet, reduces diarrheal diseases in a peri-urban population of Tamale, Ghana.
- Trial name
- NCT00252928
- Testing
- Sodium dichloroisocyanurate (NaDCC) tablets
- Where
- 3 sites in United States, Ghana
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Healthy
Photodynamic Therapy (PDT) for Oral Disinfection
Photodynamic therapy (PDT) is a technique used for the oral disinfection. In dentistry, PDT for microbial inactivation may reduces both dental plaque and risk of developing caries as well as contributes to treat gingivitis…
- Trial name
- NCT02152475
- Testing
- mouthwash with curcumin, blue LED illumination
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pain, Postoperative
Effect of Different Root Canal Disinfection Procedures on Postoperative Pain
This clinical study evaluated the effects of different root canal disinfection procedures on postoperative pain. Patients requiring root canal treatment received one of several disinfection methods.
- Trial name
- EDRCD-PP (NCT07355816)
- Testing
- Conventional Needle Irrigation, Passive Ultrasonic Irrigation, Sonic Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cumhuriyet University
Peri-implant Mucositis
Non-surgical Mechanical Debridement With or Without Full-mouth Disinfection in the Treatment of Peri-implant Mucositis
To evaluate the naturally occurring peri-implant mucositis (PM) treatment by means of non-surgical sub-marginal peri-implant instrumentation (NSPI) with or without full-mouth disinfection approach (FMD).
- Trial name
- NCT05711576
- Testing
- Full mouth disinfection
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Catania
Periodontitis
Anti-infectious Therapy of Periodontitis - Comparison of Different Clinical Strategies
It is the aim of the study to evaluate the efficiency of "One stage full mouth disinfection" according to the original protocol (Quirynen et al.
- Trial name
- NCT03509233
- Testing
- Q-SRP, FMS, FMD
- Where
- 5 sites in Germany, Romania
- Volunteers
- 228 people
- Sponsor
- RWTH Aachen University
Problems With Dentures
Evaluation of Sodium Hypochlorite as a Denture Cleanser
The present study tried to integrate all aspects of denture care: patient satisfaction with the treatment, denture decontamination and base material defects after decontamination processing.
- Trial name
- NCT01616355
- Testing
- Sodium hypochlorite immersion
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Primary Root Caries
Clinical Effect of Photoactivated Disinfection on Primary Root Carious Lesions After Partial Caries Removal
The problem of root caries has been increasing in last decades as the an average life expectancy is rising. Due to progress of medicine and dentistry humans also maintain natural dentition longer.
- Trial name
- PAD (NCT03186352)
- Testing
- photoactivated disinfection
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Pulp Necrosis, Root Canal Infection
Comparison of Ultrasonic vs 980-nm Diode Laser Irrigant Activation for Reducing Residual Bacterial DNA in Necrotic Teeth
This randomized clinical trial aimed to compare residual oral bacterial DNA detection after ultrasonic irrigant activation and 980-nm diode laser irrigant activation during root canal treatment of necrotic single-rooted teeth.
- Trial name
- NCT07607028
- Testing
- Ultrasonic Activation, 980-nm Diode Laser Activation
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Hasanuddin University
Endodontic Treatment, Periapical Diseases
Effectiveness of Photodynamic Therapy in the Disinfection of Root Canals in Patients With Apical Lesion
The object of the present study is to compare the effectiveness of conventional endodontic treatment with that of endodontic treatment combined with Photodynamic Therapy (PDT) in patients with apical lesion.
- Trial name
- PDT (NCT05916859)
- Testing
- Group 2 PDT (10 s), Group 3 PDT 20 s
- Where
- Chile
- Volunteers
- 159 people
- Sponsor
- Universidad de La Frontera
Spinal Diseases, Spinal Fusion
Intraoperative Disinfection by Pulse Irrigation With Povidone-Iodine Solution in Spine Surgery
The purpose of this study was to evaluate the efficacy, in preventing Spinal Surgical Infection, of intraoperative pulsatile irrigation with a 2000-ml saline solution of PVP-Iodine in a group of patients undergoing complex spine…
- Conditions
- Spinal Diseases, Spinal Fusion, Spine Injury, Infection, Hospital
- Trial name
- NCT03249363
- Testing
- Group A - Pulsed PVP-I Irrigation
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata