Clinical trials: Disk Prolapse
Pain, Lumbar Disc Herniation
The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation
This study will investigate whether two clinical tests can be used to diagnose and predict the outcome in patients with lumbar disc herniation undergoing surgery and non-surgery treatment.
- Conditions
- Pain, Lumbar Disc Herniation, Back Pain, Spinal Diseases
- Trial name
- NCT03832036
- Testing
- Paraspinal Mapping and Quantitative Sensory Pain Test
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Spine Centre of Southern Denmark
Herniated Lumbar Disc
High Power Laser Therapy for Herniated Disc and Lumbosacral Radiculopathy
To determine the effect of high-power laser therapy on the size of herniated disc and functional outcome in patients with lumbosacral radiculopathy.
- Trial name
- NCT06831227
- Testing
- High power Laser Therapy, physical therapy exercise program and hot pack
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Lumbar Disc Herniation, Acute Pain
Short-Term Effects of Dynamic Taping in Patients With Lumbar Disc Herniation
Previous evidence has shown that kinesio tape application reduces pain levels and improves disability in patients with chronic low back pain due to lumbar disc herniation.
- Trial name
- NCT05940519
- Testing
- Dynamic taping technique
- Volunteers
- 34 people
- Sponsor
- NAİME ULUG
Surgical Wound Infection
Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery
The purpose of the study is to determine whether a single, pre-operative dose of cefuroxime is effective in preventing surgical site infection in patients undergoing surgery for herniated disk
- Trial name
- NCT00530400
- Testing
- cefuroxime
- Where
- 2 sites in Switzerland
- Volunteers
- 1,369 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Low Back Pain and Core Muscle, Disc Herniation
Neural Control and Mechanosensation in Spine Muscle
Low back pain (LBP) is a condition that affects a majority of the US population and is responsible for a significant proportion of health care costs and utilization.
- Trial name
- NCT07003802
- Testing
- Resistance exercise
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Paresis, Lumbar Disc Herniation
Validation of a Methodology Using Isometric Dynamometer for Ankle STrength Assessment to Quantify LDH-induced Paresis
Lumbar disc herniation (LDH) is a common condition that may cause lower limb motor weakness (paresis), particularly affecting ankle dorsiflexion and plantarflexion.
- Trial name
- VAST-LDH (NCT07763522)
- Testing
- Strength test validity and reliability
- Where
- Finland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Lumbar Disc Herniation
Comparative Study Between UBE and PETD for the Treatment of Lumbar Spinal Canal Stenosis
OBJECTIVE Both unilateral biportal endoscopy technique(UBE) and percutaneous endoscopic transforaminal discectomy(PETD) are minimally invasive and effective surgical procedures for lumbar spinal stenosis.The object of this…
- Trial name
- NCT05033457
- Testing
- unilateral biportal endoscopy technique or percutaneous endoscopic transforaminal discectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shaanxi Provincial People's Hospital
Radiculopathy, Spinal Stenosis
Steroid Injections Given at the "Level of MRI Pathology" Versus at the "Level of Clinical Symptoms" to See if One is More Effective Than the Other.
Patients are being asked to participate in a research study because the patients are being treated for low back pain and the patients have decided to have an epidural steroid injection.
- Conditions
- Radiculopathy, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT02196883
- Testing
- Transforaminal Epidural Steroid Injection
- Where
- United States
- Sponsor
- State University of New York - Upstate Medical University
Lumbar Disc Herniation, Degenerative Disc Disease
Peri-Incisional Drug Injection in Lumbar Spine Surgery
This is a randomized prospective study that will compare the use of narcotics in a control group of non-injected patients with a treatment arm of patients injected intra-operatively with a ropivacaine, morphine, and epinephrine…
- Conditions
- Lumbar Disc Herniation, Degenerative Disc Disease, Spondylolisthesis
- Trial name
- NCT03513445
- Testing
- Morphine, Epinephrine, naropin
- Where
- United States
- Sponsor
- University of Minnesota
Cervical Foraminal Stenosis, Cervical Disc Herniation
Safety and Efficacy of Electromagnetic Navigation System Assisted Percutaneous Endoscopic Lumbar Decompression
There is a shallow learning curve with TELD (transforaminal endoscopic lumbar discectomy). The aim of this study is to assess the safety and efficacy of TELD assisted by electromagnetic navigation for treating lumbar disc…
- Trial name
- NCT05270486
- Testing
- Electromagnetic navigation system
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Régional de la Citadelle
Lumbar Herniated Disc
Percutaneous Transforaminal Endoscopic Discectomy vs Microendoscopic Discectomy for Treatment of Lumbar Disc Herniation
The purpose of this study is to evaluate the effectiveness of two minimal invasive endoscopic discectomy, PTED and MED, for the treatment of symptomatic lumbar disc herniation.
- Trial name
- NCT01997086
- Testing
- Percutaneous transforaminal endoscopic discectomy (PTED), Microendoscopic discectomy (MED)
- Where
- China
- Volunteers
- 125 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Infection, Intervertebral Disc Herniation
Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID)
Subclinical infection of the intervertebral disc after lumbar disc herniation surgery has been correlated to chronic low back pain and vertebral endplate changes. The most commonly reported agent is Propionibacterium acnes.
- Conditions
- Infection, Intervertebral Disc Herniation, Propionibacterium Infection, Spinal Diseases
- Trial name
- SPInE-ID (NCT03158766)
- Testing
- Microdiscectomy
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- Hospital Israelita Albert Einstein
Lumbar Degenerative Disc Disease
TRIUMPH Lumbar Artificial Disc IDE: A Pilot Study
The purpose of this investigation is to evaluate the safety and effectiveness of the TRIUMPH® Lumbar Artificial Disc for the treatment of patients who are suffering from Degenerative Disc Disease (DDD) at one level from L1 to S1.
- Trial name
- NCT01198470
- Testing
- TRIUMPH® Lumbar Artificial Disc
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Globus Medical Inc
Postoperative Pain, Erector Spinae Plane Block in Spinal Surgery
Open Technique Erector Spinae Plane Block in Spinal Surgery
Erector spinae plane (ESP) block is an interfacial plane block with visceral and somatic analgesic activity at paraspinal muscles.ESPB has been successfully applied as a part of multimodal analgesia in treating postoperative pain…
- Trial name
- NCT06157762
- Testing
- Erector spinae plane block, Erector spinae plane block performed by surgeon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Cervical Stenosis, Disk, Herniated
Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we…
- Conditions
- Cervical Stenosis, Disk, Herniated, Spondylosis
- Trial name
- NCT05356286
- Testing
- epidural electrical stimulation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Los Angeles
Lumber Disc Prolapse
H-Reflex-Guided Direction-Sensitive Exercise Versus Standard Extension Exercise for Functional Recovery in Patients With Lumbar Disc Prolapse
This randomized controlled trial will compare H-reflex-guided direction-sensitive exercise with standard extension exercise in patients with lumbar disc prolapse.
- Trial name
- NCT07871422
- Testing
- H-Reflex-Guided Direction-Sensitive Exercise, Standard Lumbar Extension Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Disc Disease
Epidural Steroid Following Discectomy for Herniated Disc Reduces Morbidity
Focus of this study is evaluation of the outcome, neurologic impairment and safety of epidural steroide following lumbar discectomy for herniated disc disease.
- Trial name
- NCT01499641
- Testing
- Methylprednisolone
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Necrosis of Femoral Head, Knee Osteoarthritis
Probiotics Attenuate Postoperative Cognition Decline
The aim of this study was to evaluate whether perioperative probiotics can reduce the incidence of postoperative cognitive dysfunction and postoperative delirium.
- Conditions
- Necrosis of Femoral Head, Knee Osteoarthritis, Fracture of Neck of Femur, Lumbar Disc Herniation
- Trial name
- NCT04017403
- Testing
- Bifidobacterium triple live capsule
- Where
- 3 sites in China
- Volunteers
- 220 people
- Sponsor
- RenJi Hospital
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Endoscopic Spinal Surgery
Application of 3D printing guide plate in endoscopic spinal surgery
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radicular Pain, Low Back Pain
- Trial name
- NCT05632835
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Prolapse With Radiculopathy
HYBRID TELE-REHABILITATION VERSUS CLINIC-BASED THERAPY IN PATIENTS WITH LUMBAR RADICULOPATHY: A RANDOMIZED CONTROLLED TRIAL
A single blinded clinical randomized trial. A single blinded trained investigator examined all patients and collect all data to eliminate inter- investigator error.
- Trial name
- NCT07041476
- Testing
- Exercise, telemedicine
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Ahmed Adel Eid