Clinical trials: Disorder, Mood
Anxiety Disorder, Mood Disorder
Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.
The purpose of this study is to determine whether or not spiritual and/or religious commitment affects mood variability and thoughts of suicide.
- Trial name
- NCT00225459
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Saskatchewan
Bipolar Disorder, Mania
Peroxisomal Defects and Familial Risk for Bipolar Disorder
The purpose of this study is to screen for peroxisome defects in child and adolescent offspring of Bipolar Disorder I (BD-I) parents at different stages of risk for transitioning to mania and following the onset of mania.
- Trial name
- NCT01237379
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Depressive Disorder, Major
Major Depressive Disorder In The Elderly
This is a placebo-controlled study evaluating the effectiveness of medication in elderly subjects with Major Depressive Disorder (MDD).
- Trial name
- NCT00093288
- Testing
- bupropion XL
- Where
- 16 sites in Australia, Belgium and 4 more
- Volunteers
- 364 people
- Sponsor
- GlaxoSmithKline
Depressive Disorder
Efficacy Study of a Computer Decision Support System to Treat Depression
The purpose of this study was designed to test the feasibility and effectiveness of implementing a Computerized Decision Support System for depression (CDSS-D) during acute care in a primary care setting.
- Trial name
- CDSS-D (NCT00551083)
- Testing
- Computerized Decision Support System for Depression (CDSS-D), Usual Care (UC)
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Major Depressive Disorder, Healty Controls
Inflammatory Markers as Predictors of the Efficacy of Electroconvulsive Therapy (ECT) in Major Depression Patients
Background: ECT is an effective treatment indicated for patients with treatment resistant depression. Although most patients display some degree of recovery, 32-52% do not respond or remit at all.
- Trial name
- ECT MDD (NCT06439797)
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- The Chaim Sheba Medical Center
Depressive Disorder, Major, Post Traumatic Stress Disorder
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
The proposed study will assess the combined effect of perampanel and ketamine on the anti-depressant response in individuals with treatment resistant depression.
- Trial name
- NCT05915013
- Testing
- Ketamine, Perampanel
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Perinatal Depression, Post Partum Depression
Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model
The proposed study involves experimentally manipulating reproductive hormones in nonpregnant, euthymic women to create a scaled down version of the changes that occur during pregnancy and the postpartum period.
- Conditions
- Perinatal Depression, Post Partum Depression, Depression, Postpartum, Depression
- Trial name
- NCT04051320
- Testing
- Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Depressive Disorder
PAXIL CR Bioequivalence Study
This study is to determine if controlled release paroxetine tablets manufactured at two different sites behave similarly in healthy volunteers.
- Trial name
- NCT00749359
- Testing
- Paxil CR
- Where
- 2 sites in United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Insomnia, Post Partum Depression
Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression
The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms.
- Trial name
- PPD (NCT03596879)
- Testing
- dCBTI, Sleep Education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Henry Ford Health System
Treatment Resistant Depression, Major Depressive Disorder
Clinical Study of GH001 in Depression
The aim of the study is to investigate the safety of GH001 (containing 5-methoxy-dimethyltryptamine; 5-MeO-DMT), and to investigate its effects on severity of depressive symptoms, and its dose-related psychoactive effects in…
- Conditions
- Treatment Resistant Depression, Major Depressive Disorder, Depression
- Trial name
- NCT04698603
- Testing
- 5 Methoxy N,N Dimethyltryptamine
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- GH Research Ireland Limited
Maternal Distress
Essential Coaching for Every Mother, a Postpartum Text Message Program for Canadian Mothers
The purpose of this study is to evaluate a text message-based program called Essential Coaching for Every Mother which sends daily text messages during the immediate six-week postnatal period.
- Trial name
- ECEM (NCT04730570)
- Testing
- Essential Coaching for Every Mother
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Major Depressive Disorder
Metyrapone as Additive Treatment in Major Depression
The purpose of this study is to test whether metyrapone is an effective and safe augmenting agent in the treatment of major depression.
- Trial name
- NCT00125554
- Testing
- Metyrapone
- Where
- Germany
- Volunteers
- 63 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Major Depression
Multicenter Comparative Study of the Activity of the Medial Prefrontal Cortex in Vulnerability to Depression
To examine whether the medial prefrontal cortex displays an increased activity during self-referential processing among remitted depressed patients compared to healthy controls
- Trial name
- CORVAD (NCT02171923)
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Menopause, Menopausal Symptoms
A Clinical Trial to Evaluate the Effects of A Supplement on Symptoms of Menopause and Overall Well-being
This study evaluates the effects of Primal Harvest's Primal Meno+ supplement on symptoms of menopause and overall well-being in females aged 40-60 who are currently menopausal and experiencing at least two menopausal symptoms.
- Conditions
- Menopause, Menopausal Symptoms, Hot Flashes, Night Sweats
- Trial name
- NCT07903480
- Testing
- Primal Meno+ Supplement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Primal Harvest, LLC
Healthy
A Multiple Ascending Dose Study of BCI-838 in Healthy Volunteers
This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of BCI-838 and its metabolite BCI-632 in healthy male and female subjects.
- Trial name
- NCT01548703
- Testing
- BCI-838
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BrainCells Inc.
Depressive Disorder, Major, Postpartum Depression
Mommy-Baby Treatment for Perinatal Depression
Perinatal depression is a major public health problem, affecting 15% of women during pregnancy through the postpartum period, with adverse consequences for the mother, the fetus, the infant, and the family.
- Trial name
- NCT01744041
- Testing
- Dyadic Interpersonal Psychotherapy, Enhanced Treatment as Usual
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Parenting Self Efficacy, Postpartum Depression
Essential Coaching for Every Mother in Tanzania
The purpose of this study is to evaluate a text message intervention called Essential Coaching for Every Mother in Tanzania to improve mothers' access to essential newborn care information during the immediate six-week postnatal…
- Conditions
- Parenting Self Efficacy, Postpartum Depression, Postpartum Anxiety, Breastfeeding Self-Efficacy
- Trial name
- ECEMTZ (NCT05362305)
- Testing
- Essential Coaching for Every Mother
- Where
- Tanzania
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Parkinson Disease, Fluctuating Mood Symptoms
Validation of the Neuropsychiatric Fluctuations Scale (EFN-VALID))
Neuropsychiatric fluctuations (NF) are among the most disabling non motor fluctuations in Parkinson disease (PD). The investigators developed the NF-scale for acute assessment of non-motor neuropsychiatric fluctuations between…
- Trial name
- EFN-VALID (NCT04455074)
- Testing
- FN scale auto-questionnaire
- Where
- 6 sites in France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Grenoble
Mood Disorder, Anxiety Disorder
Validation of an Automated Online Language Interpreting Tool - Phase Two.
There is a pressing national need to provide higher-quality, more effectively accessible language interpretation services to improve the health outcomes of Americans who have limited English proficiency (LEP).
- Conditions
- Mood Disorder, Anxiety Disorder, Substance Use Disorder, Chronic Medical Condition
- Trial name
- NCT03538860
- Testing
- Active comparator: Human interpreter, Intervention: Asynchronous Telepsychiatry
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Depression, Depressive Disorder
Beyond Ageing Project: A Study for the Prevention of Depression
The purpose of this study is to determine whether folate and vitamin B12, physical activity and mental health literacy can prevent depression, and folate and vitamin B12 and physical activity can prevent cognitive impairment in…
- Trial name
- NCT00214682
- Testing
- Folate (400mcg) and Vitamin B12 (100 mcg), mediated physical activity promotion, Mental health literacy
- Where
- Australia
- Volunteers
- 909 people
- Sponsor
- Australian National University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.