Clinical trials: Disorder, Mood
Exhaustion; Syndrome
Effects of Acute Physical Activity in Patients With Exhaustion Disorder
A new stress-related diagnosis, Exhaustion disorder (ED), was introduced in the Swedish version of ICD-10 in 2005 and has since then increased rapidly.
- Trial name
- NCT06429423
- Testing
- Acute exercise low intensity, Acute exercise moderate intensity
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Victoria Blom
Depressive Disorder, Anxiety Disorders
Happy Nurse Project: Lifestyle Interventions to Maintain Healthy Mental State in Hospital Nurses
The study is to explore the effectiveness of omega-3 fatty acids and mindfulness-based stress management program to maintain healthy mental state in hospital nurses.
- Trial name
- HNP (NCT02151162)
- Testing
- Mindfulness-based stress management program, Omega-3 fatty acids pills, Psychoeducation leaflet
- Where
- 2 sites in Japan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Center of Neurology and Psychiatry, Japan
Major Depressive Disorder
Family Psychoeducation for Major Depressive Disorder
The aim of the present study is to compare an intervention consisting of Family Psychoeducation (FPE) to an active control intervention of social support for relatives of patients with a diagnosis of major depression.
- Trial name
- NCT02348827
- Testing
- Family psychoeducation, Social support group
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Bipolar Disorder
Deep Brain Stimulation for the Treatment of Refractory Bipolar Disorder
Bipolar Disorder (BD) is among the most comon and challenging conditions in psychiatry. Although episodes of mania and hypomania define the different types of the disorder, the clinical picture is one dominated by depressed mood…
- Trial name
- NCT01476527
- Testing
- Deep Brain Stimulation
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto
Major Depressive Disorder (MDD)
Effectiveness of Walking Exercise in Improving Depression in Older Adults With Major Depressive Disorder, A Pilot Study
1. This pilot randomized controlled trial aims at investigating the effects of different intensities of aerobic walking exercise to alleviate depression in older adults with major depressive disorder.
- Trial name
- NCT04403373
- Testing
- Waitlist control, Moderate-intensity walking exercise, Vigorous-intensity walking exercise
- Where
- Hong Kong
- Volunteers
- 35 people
- Sponsor
- The University of Hong Kong
Insomnia, Major Depressive Disorder
The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using Actigraphy
The purpose of this study is to investigate exploratorily the effect of ramelteon 8 mg once daily for 8 weeks in the treatment of insomnia patients with depression by using actigraphy.
- Trial name
- NCT02669082
- Testing
- Ramelteon
- Where
- 7 sites in Japan
- Volunteers
- 26 people
- Sponsor
- Takeda
Mood Disorders, Diagnosis, Psychiatric
Wearable Devices System Diagnoses Mood Disorder in Children and Adolescents
As a diagnostic test, this study aims to explore the effectiveness of systems based on wearable devices in identifying mood disorders in children and adolescents.
- Trial name
- NCT06213220
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Institute of Psychology, Chinese Academy of Sciences
Urinary Incontinence,Stress, Urinary Incontinence, Urge
Association of Urinary Incontinence With Depression, Insomnia, Frailty and Falls in Older Adults
The aim of our study is to provide a holistic analysis of the geriatric syndromes associated with urinary incontinence, which can result in significant adverse outcomes in the elderly, and to explore the gender-specific…
- Conditions
- Urinary Incontinence,Stress, Urinary Incontinence, Urge, Depressive Disorder, Insomnia
- Trial name
- NCT06627400
- Where
- Turkey (Türkiye)
- Volunteers
- 635 people
- Sponsor
- Kastamonu University
Depression, Depressive Disorder
Remote Coaching for Supporting the Implementation of Depression Care in Primary Care in Rural India
This cluster-randomized hybrid type-II implementation superiority trial will include 14 rural primary care facilities in Madhya Pradesh, which will implement a collaborative depression care packaged based on the WHO mhGAP…
- Conditions
- Depression, Depressive Disorder, Psychological, Noncommunicable Diseases
- Trial name
- ESSENCE-IT (NCT05264792)
- Testing
- Enhanced Implementation Support, Routine Implementation Support
- Where
- India
- Volunteers
- 14 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Depression
Childhood Adversity, Genetic Polymorphisms and Stress in First Onset Major Depression
The Blue Sky Project, a 5-year study funded by the Canadian Institutes of Health Research, seeks to examine how genetics and early life experiences work together to cause a person's very first onset of depression by increasing…
- Trial name
- NCT00517764
- Testing
- escitalopram
- Where
- 2 sites in Canada
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Bipolar Disorder Depression
Minocycline and Aspirin in the Treatment of Bipolar Depression
The purpose of this study is to determine whether minocycline and aspirin are effective in the treatment of depression in individuals with bipolar disorder.
- Trial name
- Minocycline (NCT01429272)
- Testing
- Minocycline, Aspirin
- Where
- 3 sites in United States
- Volunteers
- 99 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Sleep Quality
Magnesium Supplement for Sleep Quality in Women With Poor Sleep
This study will test whether a magnesium supplement (Magnesium Breakthrough) improves sleep quality and mood in women ages 35 to 60 who have poor sleep but no diagnosed sleep disorder.
- Trial name
- NCT07708857
- Testing
- Magnesium Breakthrough
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jacksonville University
Anhedonia, Major Depressive Disorder (MDD)
Efficacy of kTMP, a Novel Non-invasive Brain Stimulation Method, for the Treatment of Anhedonia
The goal of this proposal is to provide a first assessment of the efficacy of our innovative non-invasive brain stimulation system, kTMP, in the treatment of anhedonia in MDD.
- Trial name
- kTMP Anhedonia (NCT07032428)
- Testing
- A new non-invasive brain stimulation tool
- Volunteers
- 104 people
- Sponsor
- Magnetic Tides
Treatment Resistant Depression
Exercise in Treatment Resistant Depression (TRD): A Feasibility Study
The objective of this study is to determine the effects of adjunct exercise in treatment resistant depression. The central hypothesis for the research is that adjunct exercise with usual care in Treatment Resistant Depression…
- Trial name
- NCT01383811
- Testing
- Moderate Intensity Aerobic Exercise, Wait-list
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Milton S. Hershey Medical Center
Bipolar Disorder
Genetic Predictors of Lithium Response in Bipolar Disorder
The purpose of this study is to identify genetic predictors of lithium response in bipolar disorder.
- Trial name
- NCT00252577
- Testing
- Lithium treatment
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- VA Office of Research and Development
Neurodegenerative Disease, Dementia
Cognition and Affective Research in China
This is a prospective cohort study of patients with cognitive impairment mood disorders and behavioral disorders. Comprehensive baseline and longitudinal follow-up assessments include clinical and epidemiological data, cognitive…
- Conditions
- Neurodegenerative Disease, Dementia, Alzheimer's Disease, Parkinson's Disease
- Trial name
- CARE (NCT07833267)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Depression, Bipolar Disorder
Brain Imaging in Depression
The purpose of this study is to use brain imaging technology to examine the role of certain brain receptors and the nervous system chemical acetylcholine in major depression.
- Trial name
- NCT00050700
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Environmental Exposure, Winter Depression
Health Consequences of Wintering in the French Southern and Antarctic Territories
Polar stays expose people to extreme climate, isolation and confinement. The combination of these factors induces psychological disorders, sleep disorders, immune and endocrine disturbances, and deficiencies.
- Conditions
- Environmental Exposure, Winter Depression, Endocrine System Diseases, Sleep Disorder
- Trial name
- MediTAAF (NCT04768621)
- Testing
- Questionary
- Where
- Reunion
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Single Seizure, Epilepsy
Seizure Recurrence After Unprovoked First Seizure
One in 10 people have a seizure during their life. Usually no cause is identified. Seizures without an identified cause are called unprovoked first seizure (UFS). Most people with UFS do not have further seizures.
- Trial name
- NCT05724719
- Where
- 2 sites in Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Dr. Gavin Winston
Schizophrenia, Schizoaffective Disorder
Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors
The goals of this study are to replicate previous findings of genetic predictors of response to clozapine and other antipsychotic drugs.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depression
- Trial name
- NCT00178932
- Testing
- genetic analysis, genetic assay
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Northwestern University
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