Clinical trials: Disorder, Mood
Major Depressive Disorder
Group Metacognitive Therapy vs Clinical Management for Depression
The main aims of the study are to (1) compare the effectiveness of Group metacognitive therapy (GMCT) treatment to that of clinical management and (2) explore patterns of change and investigate factors associated with treatment…
- Trial name
- NCT03711123
- Testing
- Group metacognitive therapy, Clinical management
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- University of Oslo
Depressive Disorder, Anxiety Disorder
Feasibility of Process-based Therapy in a Naturalistic Setting
The main objective is to explore the feasibility of Process-based Therapy in a natural mental health care setting delivered by practitioners.
- Trial name
- PBaPP (NCT06530888)
- Testing
- Process-based Cognitive Behavioral Therapy (PBT), Routine practice (r-PT)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Goethe University
Major Depressive Disorder, Cognitive Dysfunction
Musical Attention Control and Executive Function Training for Adults With MDD
The investigators have developed music-based cognitive training sessions derived from Neurologic Music Therapy (NMT) techniques.
- Conditions
- Major Depressive Disorder, Cognitive Dysfunction, Suicide
- Trial name
- NCT05694156
- Testing
- Music-based cognitive training
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Unity Health Toronto
Major Depressive Disorder, Generalized Anxiety Disorder
Augmenting Mental Health Support Through a Supportive Text Messaging Program
Patients seeking mental health care and those being discharged from psychiatric units frequently express psychological distress.
- Conditions
- Major Depressive Disorder, Generalized Anxiety Disorder, Mental Health Wellness 1
- Trial name
- Text4Support (NCT05411302)
- Testing
- Mental health supportive text messages
- Where
- Canada
- Volunteers
- 1,500 people
- Sponsor
- Vincent Agyapong
Rheumatoid Arthritis, Inflammatory Arthritis
Sleep and Exercise in Rheumatoid Arthritis
Regular physical activity is important for people with rheumatoid arthritis (RA). Sleep requirements for adults should be on a 'sleep needs spectrum' of between 7 to 9 hours per day.
- Trial name
- NCT03140995
- Testing
- Walking Programme
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital of Limerick
Depression - Major Depressive Disorder, Anxiety
Feasibility and Acceptability of an E-learning Dialectical Behavior Therapy Skills Course
Dialectical behavior therapy (DBT) is a comprehensive, third-wave psychological intervention designed for patients with complex and severe behavioral, emotional, and interpersonal dysfunction.
- Conditions
- Depression - Major Depressive Disorder, Anxiety, Depression, Stress
- Trial name
- NCT07088939
- Testing
- dialectical behavior therapy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Windsor
Major Depressive Disorder
Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder
This randomized, double-blind, placebo-controlled, multicenter study will evaluate the effects of NMRA-335140 (formerly BTRX-335140) on symptoms of depression in participants with Major Depressive Disorder (MDD).
- Trial name
- NCT06058039
- Testing
- NMRA-335140
- Where
- 71 sites in United States, Bulgaria and 6 more
- Volunteers
- 422 people
- Sponsor
- Neumora Therapeutics, Inc.
Major Depressive Disorder
Magnesium Bisglycinate in Major Depressive Disorder
Depression is a common illness that can affect a person's mood, sleep, energy, ability to work, and overall quality of life. While medicines are available to treat depression, many people do not get complete relief from their…
- Trial name
- DReAM-BiG (NCT07633080)
- Testing
- Magnesium Bisglycinate, Microcrystalline cellulose
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Bipolar Disorder, Involutional Depression
Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial
This study will examine the effectiveness of omega-3 fatty acids, compounds found in plants and fish, in treating bipolar disorder. Some studies have indicated that omega-3 fatty acids may be effective in treating mood disorders.
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001146
- Testing
- Ethyl Eicosapentaenoic Acid, OmegaBrite
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Mental Health (NIMH)
Moderate Depression, Severe Depressive Episode Without Psychotic Symptoms
A Randomized Clinical Trial Comparing Active Versus Sham T-PEMF Headband Treatment for Depression
An 8-week, two-armed, randomized-controlled trial that examines the antidepressant effect of treatment with transcranial pulsed electromagnetic fields (T-PEMF) in patients diagnosed with moderate to severe depression using using…
- Conditions
- Moderate Depression, Severe Depressive Episode Without Psychotic Symptoms, Recurrent Depressive Disorder, Current Episode Moderate, Recurrent Depressive Disorder, Current Episode Severe Without Psychotic Symptoms
- Trial name
- NCT06005103
- Testing
- Treatment with MoodHeadBand (T-PEMF treatment)
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Patients Diagnosed With Severe Mental Illness
From Compliance to Alliance: Engaging Psychiatric Patients in Illness Management
The purpose of this study is to determine the benefit and impact on relapse prevention,adherence to treatment and general health indices of participation in psycho-eduational group intervention among psychiatric patients with…
- Trial name
- NCT00192751
- Testing
- Psychoeducational group sessions
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rambam Health Care Campus
Amphetamine Dependence
Dose Response of Mirtazapine to Methamphetamine Induced Interest, Mood Elevation and Reward
The primary purpose of this study is to determine if Mirtazapine will produce a decrease in interest in the drug, a decrease in mood elevation, and/or a decrease in reward when given before methamphetamine compared to placebo.
- Trial name
- NCT00600145
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Depression, Depressive Disorder, Major
Feasibility of a Technology-Based Treatment Support System
This study aims to evaluate a technology-based treatment support system for patients undergoing the treatment of depression. The investigators will explore the usefulness of the technology-based treatment support system as an…
- Trial name
- NCT03121937
- Testing
- Mobile App
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Northwestern University
Traumatic Brain Injury, Depression
The Effect of Exercise on Mood After Traumatic Brain Injury
We proposed to examine the effect of an aerobic exercise intervention on depression in persons with Traumatic Brain Injury (TBI).
- Trial name
- NCT00571545
- Testing
- Aerobic exercise, No exercise
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Washington
Major Depressive Disorder, Healthy Participants
A Study of the Neurobiology of Depression
Previous research studies have shown that depression is associated with changes in structure and activity in different parts of the brain and that antidepressant medication can affect brain activity in different parts of the…
- Trial name
- NCT01051466
- Testing
- Duloxetine
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Bipolar Disorder, Bipolar Depression
Seroquel in Bipolar Depression Versus Lithium
This study is being carried out to see if quetiapine fumarate (Seroquel) is effective in treating bipolar depression during an 8-week acute phase compared with placebo and lithium, followed by continuation treatment for 26 up to…
- Conditions
- Bipolar Disorder, Bipolar Depression, Depression
- Trial name
- NCT00206141
- Testing
- Quetiapine Fumarate (Seroquel™) drug, mood stabilizer (mood)
- Where
- 76 sites in Canada, Croatia and 14 more
- Volunteers
- 672 people
- Sponsor
- AstraZeneca
Bipolar Disorder
Adjuvant Psychotherapy for Relapse Prevention in Early Adulthood (< 35 yr.) of Bipolar Disorder
This efficacy study compares an adjuvant specific psychotherapy and an active control intervention for Bipolar Disorder under mood stabilizer to prevent relapse an maintain remission.
- Trial name
- A2BipoLife (NCT02506322)
- Testing
- SEKT - Cognitive-Behavioral-Emotional, FEST - Clinical Supportive Educational
- Where
- Germany
- Volunteers
- 318 people
- Sponsor
- University Hospital Tuebingen
Bipolar Disorder
Prevention of Relapse & Recurrence of Bipolar Depression
The purpose of this study is to determine whether the long-term use of combined antidepressant plus mood stabilizer therapy is superior to mood stabilizer therapy alone in preventing the relapse and recurrence of bipolar…
- Trial name
- NCT00961961
- Testing
- Lithium / Fluoxetine
- Where
- 2 sites in United States
- Volunteers
- 177 people
- Sponsor
- University of Pennsylvania
Major Depressive Disorder, Mood Disorders
Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder
This trial has two studies. In study 1, the investigators will explore the relationships between three psychobiological factors (sleep patterns, motor activity, and decision-making ability).
- Conditions
- Major Depressive Disorder, Mood Disorders, Bipolar Disorder (BD)
- Trial name
- MoodCatcher (NCT07427966)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Depressive Disorder
A Study of Duloxetine (LY248686) in the Treatment of Japanese Children and Adolescents With Depressive Disorder
The purpose of this long-term study is to evaluate the safety and efficacy of duloxetine hydrochloride in Japanese children and adolescents with depressive disorder.
- Trial name
- NCT03395353
- Testing
- Duloxetine Hydrochloride
- Where
- Japan
- Volunteers
- 151 people
- Sponsor
- Shionogi
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.