Clinical trials: Disorder, Mood
Bipolar Disorder
Emotion Recognition Modification for Bipolar Disorder
Previous research suggests that people with bipolar disorder have trouble accurately identifying emotions. The goal of this study is to test a novel intervention, emotion recognition modification (ERM), to help improve the…
- Trial name
- NCT02613104
- Testing
- emotion recognition modification - sad>happy, emotion recognition modification - sad>happy control, emotion recognition modification - angry>happy
- Where
- United States
- Sponsor
- Northwell Health
Bipolar Disorder
Remediation of Cognitive Dysfunction in Euthymic Bipolar Disorder Patients Using Transcranial Direct Current Stimulation (tDCS)
This study aims to investigate the potential for Transcranial Direct Current Stimulation (tDCS) to enhance cognitive functioning in euthymic bipolar patients through comparing the effect of active or sham tDCS (placebo control)…
- Trial name
- NCT01339598
- Testing
- Transcranial direct current stimulation (Eldith DC Stimulator)
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- The University of New South Wales
Bone Diseases, Metabolic, Depression, Involutional
Use of Bone Biopsy to Better Understand the Causes of Decreased Bone Mineral Density in Depression
In this study researchers would like to learn more about the low levels of bone mineral density seen in approximately half of women in their forties diagnosed as currently having or previously had depression.
- Conditions
- Bone Diseases, Metabolic, Depression, Involutional, Osteoporosis
- Trial name
- NCT00001916
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder (MDD)
Study to Evaluate Efficacy and Safety of Ropanicant in MDD Patients
The primary objective is to evaluate the efficacy of Ropanicant at two different dosage levels compared to placebo in patients with Major Depressive Disorder (MDD).
- Trial name
- NCT06836063
- Testing
- Ropanicant
- Where
- 35 sites in United States
- Volunteers
- 214 people
- Sponsor
- Suven Life Sciences Limited
Depression
Motivational Interviewing to Improve Medication Adherence Among Hispanic Adults With Depression
This study will determine the effectiveness of motivational interviewing in improving antidepressant medication adherence among Hispanics.
- Trial name
- NCT00356304
- Testing
- Motivational interviewing, Treatment as usual
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Major Depression
Neuroimaging Sleep and Mood in Depression
This study will investigate how sleep and mood are related in patients with depression and in healthy controls. It will use MRI-based measures of brain function to determine how neural systems are modulated by sleep and sleep…
- Trial name
- NCT05497414
- Testing
- Sleep deprivation
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Smoking, Bipolar Disorder
Web-Delivered Acceptance & Commitment Therapy for Smokers With Bipolar Disorder
This purpose of the study is to develop and test a new website to help people who have bipolar disorder quit smoking.
- Trial name
- WebQuit Plus (NCT02750904)
- Testing
- Experimental plus Nicotine Replacement Therapy, Control plus Nicotine Replacement Therapy
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- Fred Hutchinson Cancer Center
Major Depressive Disorder
the Safety, Tolerability, and Pharmacokinetics Study of HEC113995
Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC113995 PA•H2O in Healthy Subjects
- Trial name
- NCT04623814
- Testing
- Food, HEC113995
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Bipolar Disorder, Depression
Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder
This study will develop strategies for early detection and prevention of mood disorders and associated impairment in adolescent children of parents with bipolar disorder.
- Trial name
- NCT00338806
- Testing
- Interpersonal psychotherapy for prevention with adolescents, Educational clinical monitoring
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- New York State Psychiatric Institute
Schizophrenia, Schizophreniform Disorders
Bazedoxifene -Treatment for Women With Schizophrenia
To study the effect of adjunctive bazedoxifene - a selective estrogen receptor modulator (SERM) in a double blind, placebo-controlled adjunctive study in the treatment of women with schizophrenia.
- Conditions
- Schizophrenia, Schizophreniform Disorders, Schizo Affective Disorder
- Trial name
- NCT04113993
- Testing
- Bazedoxifene Acetate
- Where
- Australia
- Volunteers
- 160 people
- Sponsor
- The Alfred
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic iCBT for Depression and Anxiety
This 8-week, pilot randomized, controlled trial to evaluate the benefits of transdiagnostic Internet-based CBT (iCBT) in young adults with MDD, SAD, PD or GAD.
- Conditions
- Major Depressive Disorder, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT02266693
- Testing
- iCBT
- Where
- Canada
- Volunteers
- 77 people
- Sponsor
- Centre for Addiction and Mental Health
Sleep Quality, Mood
A Clinical Trial to Evaluate the Effects of the Edge+Ease PM+AM System on Mood, Mental Clarity, Sleep Quality, and Digestive Wellbeing
This is a decentralized, single-arm, open-label clinical trial evaluating the effects of the Edge+Ease PM+AM dietary supplement system on sleep quality, mood, mental clarity, focus, and digestive comfort in 35 generally healthy…
- Conditions
- Sleep Quality, Mood, Mental Clarity, Brain Fog
- Trial name
- NCT07721506
- Testing
- Edge+ease PM
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Edge+Ease
Posttraumatic Stress Disorder, Major Depressive Disorder
Positive Processes and Transition to Health (PATH)
The R33 will be a randomized controlled trial to replicate changes in the targets (unproductive processing, avoidance, reward deficits) from the R61 phase in a larger sample of 135 participants who have experienced a…
- Trial name
- NCT06093906
- Testing
- Positive Processes and Transition to Health, Progressive Muscle Relaxation
- Where
- 3 sites in United States
- Volunteers
- 135 people
- Sponsor
- Case Western Reserve University
Bipolar Disorder, Pediatric
Efficacy and Safety of Asenapine Treatment for Pediatric Bipolar Disorder (P06107 Has an Extension [P05898; NCT01349907])(P06107)
Efficacy and safety of asenapine for the treatment of bipolar I disorder (manic or mixed episodes) will be evaluated in participants between 10 and 17 years old, who are either hospitalized or non-hospitalized.
- Trial name
- NCT01244815
- Testing
- asenapine, Rescue medication
- Volunteers
- 404 people
- Sponsor
- Organon and Co
Major Depressive Disorder
A Study to Evaluate the Safety, Tolerability and Efficacy of XEN1101 in Major Depressive Disorder
This is a multicenter, Phase 2, double-blind, randomized, parallel-arm, placebo-controlled clinical trial to evaluate the efficacy, safety, and tolerability of XEN1101 in subjects with Major Depressive Disorder.
- Trial name
- X-NOVA (NCT05376150)
- Testing
- XEN1101 10 mg, XEN1101 20 mg
- Where
- 20 sites in United States
- Volunteers
- 168 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Major Depressive Disorder
Cognitive Reappraisal in Adolescents With Major Depression
Major depression (MD) is common during adolescence and associated with significant morbidity and mortality. One important factor for the development and maintenance of adolescent MD are disturbances in emotion regulation…
- Trial name
- KONNI (NCT03957850)
- Testing
- Cognitive Reappraisal Training, Control Training
- Where
- Germany
- Volunteers
- 71 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Depression, Unipolar, Depressive Disorder
Gaze Contingent Feedback in Major Depressive Disorder (MDD)
The purpose of this study is to determine whether giving gaze-contingent feedback is an effective attention modification procedure, helping in the treatment of Major Depressive Disorder (MDD)
- Conditions
- Depression, Unipolar, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02945735
- Testing
- Attention Modification
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Depression, Postpartum, Depression
Using a Preparation and Education Intervention to Reduce Postpartum Depression Among New Mothers (The MADE IT 2 Study)
This study will test an intervention that aims to prevent postpartum depression by providing new mothers with information on and resources for dealing with the disorder.
- Trial name
- NCT00951717
- Testing
- Behavioral education intervention
- Where
- United States
- Volunteers
- 590 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postpartum Depression
Emotional Freedom Techniques (EFT) and Postpartum Depression
Hypothesis 1: Pregnant women in the EFT group will have a lower test score from Edinburgh Postpartum Depression Scale, and a follow-up score of three months and six months after the last application date, compared to the control…
- Trial name
- NCT04355091
- Testing
- Emotional Freedom Techniques (EFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Istanbul University - Cerrahpasa
Depression, Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) vs. Escitalopram in Postmenopausal Women
Desvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI). This study will investigate the safety, efficacy, and tolerability of DVS SR versus escitalopram in women with major…
- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT00406640
- Testing
- Desvenlafaxine succinate sustained-release (DVS SR), Escitalopram
- Where
- 70 sites in United States, Argentina and 4 more
- Volunteers
- 595 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
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