Clinical trials: Disorder, Pediatric
Dengue Hemorrhagic Fever
Pharmacokinetics and Pharmacodynamics of Ivermectin in Pediatric Dengue Patients
Design and Outcomes This research study is designed as open-label, sequential dose-escalating clinical trial. There will be two phases of enrollment.
- Trial name
- PKIDEN (NCT03432442)
- Testing
- Ivermectin
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
PANS, PANDAS
Antibiotic Treatment Trial for the PANDAS/PANS Phenotype
The purpose of this research study is to know if the antibiotic azithromycin, an antibiotic approved by the U.S. Food and Drug Administration (FDA) for treating infections, improves symptom severity in children with sudden and…
- Conditions
- PANS, PANDAS, Obsessive Compulsive Disorder (OCD)
- Trial name
- AZT (NCT01617083)
- Testing
- Azithromycin
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of South Florida
Hip Disease, Hip Dysplasia
PENG With LFCB vs. ESP Blocks for Pediatric Hip Surgery
This randomized controlled trial (RCT) compares the analgesic effectiveness of two regional anesthesia techniques-Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve Block (LFCB) versus Lumbar and…
- Conditions
- Hip Disease, Hip Dysplasia, Hip Arthropathy
- Trial name
- NCT07023094
- Testing
- Ropivacaine 0.2% for PENG Block, Ropivacaine 0.2% for LFCB, Ropivacaine 0.2% for L-ESPB
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Acute Kidney Injury, Renal Injury
Pediatric Acute Kidney Injury (AKI) Retrospective, Real-Time and Repository Research
This proposal will incorporate statistical models developed by the investigators to predict risk for acute kidney injury into our electronic medical record system, enabling an alert to notify providers of the risk status.
- Conditions
- Acute Kidney Injury, Renal Injury, Kidney Disease
- Trial name
- PAR4 (NCT02660931)
- Testing
- AKI Risk Notification
- Where
- United States
- Volunteers
- 12,108 people
- Sponsor
- Vanderbilt University Medical Center
Childhood Obesity
Brighter Bites - Access, Continuity and Education With Fruits and Vegetables
The purpose of the research is to find out how well a new nutrition program works for elementary school students and their families. This program is called Brighter Bites.
- Trial name
- Brighter Bites (NCT02726529)
- Testing
- Brighter Bites, CATCH
- Where
- United States
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Keratoconus
The Collagen Factors of Rapid Progression of Keratoconus in Children.
The purpose of this observational study was to understand the differences in clinical features and mechanisms of keratoconus between children and adults.
- Trial name
- KCLD (NCT06722937)
- Testing
- Observation
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Congenital Disorders
Repeat Sternotomy for Pediatrics
Given the relative lack of information regarding the risks associated with repeat sternotomy in the pediatric patient population, a preliminary screen of the Children's Cardiothoracic Surgery Database was performed to determine…
- Trial name
- NCT00485745
- Volunteers
- 1,281 people
- Sponsor
- Children's Healthcare of Atlanta
Patent Ductus Arteriosus (PDA)
Outcome of Transcatheter Closure of Patent Ductus Arteriosus in Pediatric Cardiology Unit in 3 Years Duration
Transcatheter Closure of Patent Ductus Arteriosus to evaluate the outcome of percutaneous transcatheter closure of patent ductus arteriosus in children
- Trial name
- NCT06634407
- Testing
- transcatheter closure
- Volunteers
- 90 people
- Sponsor
- Assiut University
Bipolar Depression
Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients
This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I or bipolar II disorder as…
- Trial name
- NCT06372964
- Testing
- Lumateperone
- Where
- 68 sites in United States, Colombia and 2 more
- Volunteers
- 384 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Keratoconus
Iontophoretic Transepithelial Collagen Cross-linking Versus Epithelium-off Collagen Cross-linking in Pediatric Patients. Three Year Follow up.
To compare 3 year iontophoretic transepithelial corneal cross-linking (I-ON CXL) outcomes with epithelium-off collagen cross-linking (epi-off CXL)in pediatric patients.
- Trial name
- NCT03753009
- Testing
- corneal cross-linking
- Volunteers
- 28 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Ulcerative Colitis
Infliximab Accelerated Induction in Moderate to Severe Pediatric UC
Objectives: To examine the effect of accelerated infliximab induction in children with moderate to severe UC. Design: A multi-center, prospective, randomized, open label study. Setting: Pediatric gastroenterology centers.
- Trial name
- INDUCE (NCT03209232)
- Testing
- Infliximab
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Schneider Children's Medical Center, Israel
Hematologic Malignancies, Nonmalignant Diseases
Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients
Melphalan is a chemotherapy drug used extensively in bone marrow transplantation. The goal of this study is to determine what causes some children to have different drug concentrations of melphalan in their bodies and if drug…
- Conditions
- Hematologic Malignancies, Nonmalignant Diseases, Immunodeficiencies, Hemoglobinopathies
- Trial name
- NCT03609827
- Testing
- Melphalan
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Francisco
Lupus Nephritis, Children
Multicenter Registry of Pediatric Lupus Nephritis in China
This study is designed to evaluate the efficacy and safety of the current treatment option and outcome of pediatric lupus nephritis patients in China.
- Conditions
- Lupus Nephritis, Children, Steroid, Immunosuppressive Treatment
- Trial name
- NCT03791827
- Testing
- Corticosteroid, Hydroxychloroquine, Cyclophosphamide
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Xiqiang Dang
Out-Of-Hospital Cardiac Arrest, Pediatric Disorder
Etiology, Incidence and Survival of Pediatric Out-of-hospital Cardiac Arrests: a Four-year Danish Analysis
Background: OHCA is a rare condition for children and young adults. Overall incidence rates are reported as 3.3-5.97 per 100.000 inhabitants.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Pediatric Disorder, Cardiopulmonary Arrest
- Trial name
- Child-OHCA (NCT04275856)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Childhood Obesity, Overweight (BMI > 25)
Weight Status, Resilience, and Quality of Life in Indian Children
A school-based cross-sectional study that aims to generate context-specific evidence on how weight status is related to resilience, health behaviour, and quality of life among Indian adolescents.
- Conditions
- Childhood Obesity, Overweight (BMI > 25), Underweight
- Trial name
- NCT05648045
- Where
- 16 sites in India
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obstructive Sleep Apnea
Rapid Maxillary Expansion for Residual Pediatric
Randomized Controlled Trial comparing Rapid Maxillary Expansion with Standard Clinical Practice in patients with residual pediatric Obstructive Sleep Apnea Syndrome after adenotonsillectomy.
- Trial name
- ERMES (NCT02947464)
- Testing
- Standard clinical practice, Standard clinical practice + Rapid Maxillary Expansion
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Childhood Obesity, Breastfeeding
Breastfeeding in Infancy and Food Intake in Preschool-Aged Children
The purpose of this study is to compare female, preschool-aged children breastfed during infancy to female, preschool-aged children bottle-fed during infancy in their ability to adjust calorie intake in response to internal…
- Trial name
- NCT00994487
- Testing
- High Energy Density Preload, Low Energy Density Preload
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Migraine
AMG 334 20160172 Pediatric Migraine PK Study.
AMG 334 20160172 Pediatric Migraine PK Study.
- Trial name
- NCT03499119
- Testing
- AMG 334 Dose 1, AMG 334 Dose 2, AMG 334 Dose 3
- Where
- 14 sites in United States
- Volunteers
- 53 people
- Sponsor
- Amgen
PTEN Hamartoma Tumor Syndrome, Macrocephaly Autism Syndrome
PTEN Hamartoma Tumor Syndrome Pediatric Patient Registry
PtenTurkiye.org' is a national ( Turkish), web-based registry for PTEN Hamartoma Tumour ( PHTS) syndrome established in 2022. It is designed to increase awareness, gather scientific knowledge by collaboration and increase data…
- Trial name
- NCT06462430
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Yale University
Developmental Dysplasia of the Hip (DDH)
Early Outcomes of Arthroscopic Versus Open Reduction for Developmental Dysplasia of the Hip in Children
This study was designed to determine whether arthroscopic-assisted reduction offers better early surgical outcomes than open reduction for treating developmental dysplasia of the hip in children.
- Trial name
- NCT06747767
- Testing
- Arthroscopy, Open reduction
- Where
- Iraq
- Volunteers
- 43 people
- Sponsor
- Hawler Medical University
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