Clinical trials: Disorder, Pediatric
Pediatric Obesity, Pediatric Overweight
Comparing Outcomes Among Children With Obesity in a Community Healthy Lifestyle Program
This study aims to evaluate the outcomes of an existing clinical program that teaches families of children with overweight and obesity healthy lifestyle. The design will be unblinded, randomized, waitlist control.
- Conditions
- Pediatric Obesity, Pediatric Overweight, Overweight , Obesity
- Trial name
- 73357 (NCT07342855)
- Testing
- Get Up & Go Healthy Lifestyle Program
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of Texas Southwestern Medical Center
Breast Feeding, Infant Nutrition
Feeding My Baby - A National WIC Study
The goal of the study is to be a current examination of infant and toddler feeding practices among families receiving WIC services.
- Conditions
- Breast Feeding, Infant Nutrition, Childhood Obesity, Infant Feeding Patterns
- Trial name
- NCT02031978
- Volunteers
- 4,367 people
- Sponsor
- USDA Food and Nutrition Service
Arteriovenous Malformations, Arteriovenous Fistula
Endovascular Management of Pediatric Intracranial Arteriovenous Shunts
Review the outcomes of the Endovascular management of pediatric intracranial arteriovenous shunts. Give an effective treatment for pediatric intracranial arteriovenous shunts and can detect the best method could be used and…
- Trial name
- NCT03950258
- Testing
- endovascular embolization
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Pharyngitis
APC-231 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) in Pediatric Patients With Strep Throat
The purpose of this study is to evaluate the efficacy and safety of APC-231 QD for 7 days in the bacteriological outcome at the Test of Cure Visit.
- Trial name
- NCT00100126
- Testing
- Amoxicillin Pulsatile Release Multiparticluate Sprinkle
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Advancis Pharmaceutical Corporation
Schistosomiasis
Introduction of Arpraziquantel Treatment for Schistosomiasis Control in Preschool-aged Children in Endemic Areas: A Small-scale Public Health Intervention Study
The proposed small-scale pilot studies are public health intervention studies implemented through established routine programs and services in the frame of the mass drug administration (MDA) campaigns in Côte d'Ivoire, Kenya and…
- Trial name
- ADOPTpilot (NCT06698510)
- Testing
- Arpraziquantel 150mg dispersible tablet
- Where
- 7 sites in Côte d’Ivoire, Kenya and 1 more
- Volunteers
- 18,500 people, healthy volunteers welcome
- Sponsor
- Peter Steinmann
Childhood Obesity
YMCA-Physical Activity and Nutrition
There is an epidemic rise in the number of overweight and obese children. Overweight and obesity in children tracks into adulthood and carries elevated risk of chronic diseases such as seen with the metabolic syndrome (i.e.…
- Trial name
- YMCA-PAN (NCT01107678)
- Testing
- Healthy Snacks and Organized Physical Activity
- Where
- United States
- Volunteers
- 966 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Moderate to Severe Chronic Plaque-type Psoriasis
Study to Assess the Long-term Safety, Tolerability, Efficacy of Secukinumab in Pediatric Patients of Age 6 to <18 Years, With Moderate to Severe Plaque Psoriasis
This was an open-label, parallel-group, two-arm, multicenter study in pediatric subjects aged 6 years to less than 18 years, at randomization, with moderate to severe chronic plaque psoriasis.
- Trial name
- NCT03668613
- Testing
- secukinumab low dose, secukinumab high dose
- Where
- 23 sites in United States, Belgium and 7 more
- Volunteers
- 84 people
- Sponsor
- Novartis Pharmaceuticals
Acute Renal Insufficiency
Incidence of Acute Renal Failure Associated With Iodinated Contrast Agents in Pediatrics
Iodinated contrast media are now frequently used in diagnostic imaging exams, including pediatrics. In adults, the acute renal failure (ARF) associated with contrast agents (CA-AKI) occur in 3-33% of exposed patients, especially…
- Trial name
- CANOPY (NCT02955979)
- Testing
- CT scan with iodinated contrast agents
- Where
- 2 sites in France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Percutaneous Internal Ring Suturing, Pain Management
Comparison of the Postoperative Analgesic Effects of RSB and CEB in Pediatric Patients Scheduled for Percutaneous Internal Ring Suturing
Inguinal hernia is one of the most common surgical pathologies in children, and the minimally invasive percutaneous internal ring suturing (PIRS) technique is widely preferred.
- Trial name
- NCT07147062
- Testing
- Rectus Sheath Block, Caudal Epidural Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
HIV Infections
A Treatment IND for Retrovir Brand Zidovudine (AZT) Therapy of Pediatric Patients With HIV Disease
To facilitate the use of zidovudine (AZT) in children who are 3 months to 12 years of age who are HIV-infected and either symptomatic or have a CD4 cell count < 400 cells/mm3 and to monitor adverse effects of AZT.
- Trial name
- NCT00000662
- Testing
- Zidovudine
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Plaque Psoriasis
A Study to Evaluate the Drug Levels, Efficacy and Safety of Deucravacitinib in Children and Adolescent Participants With Moderate to Severe Plaque Psoriasis
The purpose of this pediatric study is to evaluate the drug levels, efficacy and safety of Deucravacitinib in children and adolescent participants aged 4 to <18 years with moderate to severe plaque psoriasis.
- Trial name
- NCT04772079
- Testing
- Deucravacitinib
- Where
- 65 sites in Argentina, Australia and 11 more
- Volunteers
- 153 people
- Sponsor
- Bristol-Myers Squibb
Autism, Autistic Disorder
Safety and Efficacy Study in the Treatment of Intestinal Problems Associated With Autism
The purpose of this study is to determine if human immunoglobulin given by mouth twice a day is effective in treating the persistent gastrointestinal (GI) problems such as diarrhea, constipation, abdominal pain, and bloating, in…
- Conditions
- Autism, Autistic Disorder, Child Development Disorders, Pervasive, Gastrointestinal Diseases
- Trial name
- NCT00110708
- Testing
- Oralgam (human immunoglobulin)
- Where
- 22 sites in United States
- Volunteers
- 120 people
- Sponsor
- PediaMed Pharmaceuticals
Hearing Loss, Screening
Adaptation of Pediatric Speech Audiometry Tests Into Other Languages
The objective of this study was to offer a comprehensive framework for the adaptation of speech audiometric tests into other languages.
- Trial name
- NCT07156825
- Where
- Hungary
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Sleep Apnea, Obstructive, Tonsillitis
Laryngeal Mask Airway in Pediatric Adenotonsillectomy
The study will compare how often the tubing kinks when a LMA (laryngeal mask airway) with modified retractor is used compared to use of an endotracheal tube (ETT) and non modified retractor is used.
- Trial name
- LMA (NCT01695980)
- Testing
- ETT with non modified retractor, LMA with modified retractor
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Eastern Virginia Medical School
Healthy Participants
Bioequivalence Study of Bosutinib Pediatric Capsule Relative to Commercial Tablet Under Fed Condition
This study is intended to establish bioequivalence of the bosutinib age-appropriate capsule formulation to the commercial tablet formulation in healthy participants under fed condition.
- Trial name
- NCT04549480
- Testing
- Bosutinib capsule, Bosutinib tablet
- Where
- 2 sites in Netherlands
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Pfizer
Neurogenic Detrusor Overactivity
Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC
The purpose of this study is to evaluate the safety, efficacy, and PK of Vibegron in pediatric participants with NDO who are regularly using CIC
- Trial name
- KANGUROO (NCT05491525)
- Testing
- Vibegron
- Where
- 38 sites in United States, Belgium and 14 more
- Volunteers
- 71 people
- Sponsor
- Urovant Sciences GmbH
Diplegia, Spastic
Eye-Hand Coordination in Children With Spastic Diplegia
This study will examine how the brain controls eye-hand coordination (visuomotor skills) in children with spastic diplegia and will determine whether impairment of this skill is related to the learning difficulties in school that…
- Trial name
- NCT00024791
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Anemia, Sickle Cell
Systematic Psychological and Medical Care for Children With SCD
Sickle cell disease (SCD), a genetically transmitted blood disease, necessitates life-long care. In children, the disease may cause intense pain and other severe complications.
- Trial name
- Drépano (NCT02022891)
- Testing
- systematic psychological care
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pediatric ALL, Critical Illness
Singapore's Health Outcomes After Critical Illness in Kids
What is the problem? Every year about 2.5 million children are affected by critical illness and require admission to the pediatric intensive care unit (PICU).
- Conditions
- Pediatric ALL, Critical Illness, Post Intensive Care Unit Syndrome
- Trial name
- SHACK (NCT04637113)
- Testing
- This is a non-interventional study
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Pediatric Obesity, Psychosocial Well-being
Childhood Obesity, Lifestyle Interventions and Psychosocial Well-being
Childhood obesity has been associated with an increased risk of impaired psychosocial well-being and the development of depression and anxiety.
- Trial name
- NCT06555380
- Testing
- The one-year intervention, The three-year intervention
- Where
- Denmark
- Volunteers
- 319 people
- Sponsor
- University of Aarhus
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