Clinical trials: Disorder Characterized by Fever
Febrile Illness, Fever Without Source
Etiology of Febrile Illness in Nepal (DEFINe Study)
In the absence of a microbiological lab testing, majority of the cases of febrile illnesses in Nepal are diagnosed on a clinical basis alone.
- Trial name
- DEFINe (NCT07004751)
- Testing
- Additional laboratory analysis, Standard of Care (SOC)
- Where
- Nepal
- Volunteers
- 194 people
- Sponsor
- Patan Academy of Health Sciences
Febrile Illness, Malaria
Rapid Diagnostic Tests (RDTs) for Malaria in Kampala, Uganda
Malaria remains a disease that causes much death and sickness, especially in sub-Saharan Africa. An accurate, simple, and inexpensive method of diagnosing malaria is urgently needed.
- Trial name
- NCT00327964
- Where
- Uganda
- Volunteers
- 600 people
- Sponsor
- University of California, San Francisco
Febrile Syndrome
Study of Febrile Syndromes After Tick Bite
Febrile syndromes after tick bites can be caused by different microorganisms: bacteria (B. miyamotoi, A. phagocytophilum, R. helvetica…), parasites (Babesia spp) and viruses (TBE virus).
- Trial name
- FebriTick (NCT05090969)
- Where
- France
- Volunteers
- 940 people
- Sponsor
- University Hospital, Strasbourg, France
Dengue, Arbovirus Infections
Improving Disease Prevention Strategies by Integrating Socio-spatial Characterization of Human Mobility
In contrast to the trend expected based on existing prediction models, dengue incidence was historically low during the pandemic mobility restrictions of 2020-2021 in most dengue endemic countries.
- Conditions
- Dengue, Arbovirus Infections, Epidemic Disease, Behavior, Health
- Trial name
- DI-MOB (NCT06599970)
- Testing
- No intervention
- Where
- Cuba
- Volunteers
- 810 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Bloodstream Infection, Health Care Utilization
Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo
Bloodstream infections are frequent in children admitted to the hospital for severe febrile illness in sub-Saharan Africa.Ongoing blood culture surveillance at Kisantu Hospital showed non-typhoidal Salmonella (NTS) as the first…
- Conditions
- Bloodstream Infection, Health Care Utilization, Malaria,Falciparum, Salmonella Infection Non-Typhoid
- Trial name
- HIT BSI (NCT04289688)
- Where
- Democratic Republic of the Congo
- Volunteers
- 784 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Febrile Illness
Febrile Illness in Kinshasa and Kimpese
This is a bi-centric prospective observational cohort study of adults and children presenting to the emergency room or outpatient department with community febrile illness (with or without signs of focalization) in 2 clinical…
- Trial name
- FIKI² (NCT04760678)
- Testing
- Observational study
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 1,046 people
- Sponsor
- Institute of Tropical Medicine, Belgium
Acute Febrile Illness
Electronic Algorithms Based on Host Biomarkers to Manage Febrile Children
Health professionals in developing countries have limited ability to identify children at risk of dying and those in need of antibiotics.
- Trial name
- e-POCT (NCT02225769)
- Testing
- Management of febrile children using e-POCT, Management of febrile children using ALMANACH
- Where
- Tanzania
- Volunteers
- 3,192 people
- Sponsor
- Swiss Tropical & Public Health Institute
Febrile Illness
Epidemiology and Clinical Characteristics of Emerging and Re-emerging Infectious Diseases With Epidemic Potential in Mali
This is a prospective observational study to include participants with a spectrum of emerging or unknown pathogens with the objective to determine etiology and clinical characteristics of those diseases.
- Trial name
- ECERID (NCT05441800)
- Testing
- Observational Study
- Where
- Mali
- Volunteers
- 400 people
- Sponsor
- University Clinical Research Center, Mali
Antibiotic Prescription
Management and Outcome of Fever in Children in Europe
This is an observational study assessing the management and outcome of children presenting to Emergency Departments (ED) with fever across Europe.
- Trial name
- MOFICHE (NCT05221437)
- Testing
- antibiotic prescription
- Volunteers
- 38,480 people
- Sponsor
- Imperial College London