Clinical trials: Disorder of Hip Joint
Orthopedic Disorder, Arthropathy of Knee
Study to Reduce Sitting in Older Adults Undergoing Hip or Knee Replacements
The aim of this study is to investigate the feasibility of an intervention to reduce sedentary behaviour in older adults waiting for hip and knee replacements.
- Conditions
- Orthopedic Disorder, Arthropathy of Knee, Arthropathy of Hip, Sedentary Lifestyle
- Trial name
- INTEREST (NCT03740412)
- Testing
- Sedentary behaviour reduction using motivational interviewing, education, individualised feedback, goal-setting, self-monitoring, environmental modification, and supportive phone calls
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Birmingham
Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Knee
Extended Post-operative Oral TXA in Primary THA
The goal of this clinical trial is to learn if extended post-operative oral tranexamic acid (TXA) - a medication that reduces bleeding by slowing the breakdown of blood clots - can improve functional recovery following surgery in…
- Trial name
- NCT07685743
- Testing
- Extended oral tranexamic acid regimen
- Volunteers
- 170 people
- Sponsor
- Oregon Health and Science University
Lumbar Spondylosis, Cervical Spondylosis
Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
The purpose of this research is to determine if post-operative cognition will be better if the general anesthesia for surgery is done with an inhaled (gas through a breathing tube) or intravenous (medicine injected in the IV)…
- Conditions
- Lumbar Spondylosis, Cervical Spondylosis, Hip Osteoarthritis, Knee Osteoarthritis
- Trial name
- NCT00788008
- Testing
- inhalation anesthesia with isoflurane vs. TIVA with propofol
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Coxarthrosis, Arthroplasties Hip Replacement
Use of Etoricoxib Compared to Diclofenac in the Perioperative Treatment of Patients After Total Hip Arthroplasty
The primary aim of this study is to test if etoricoxib decreases the perioperative blood loss compared to diclofenac. Secondary questions to be explored are: Does etoricoxib prevent Heterotopic ossification after Total Hip…
- Conditions
- Coxarthrosis, Arthroplasties Hip Replacement, Perioperative Blood Loss
- Trial name
- NCT01229774
- Testing
- Etoricoxib, Diclofenac
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Regensburg
Anemia
A Study to Evaluate the Safety and Efficacy of Epoetin Alfa Versus Placebo to Reduce the Need for Blood Transfusions and Reduce the Occurrence of Severe Anemia During the Time Period Surrounding Total Hip Replacement Surgery
The purpose of this study is to evaluate the safety and effectiveness of two different dosing schedules of epoetin alfa versus placebo for decreasing the need for blood transfusions and preventing the occurrence of severe anemia…
- Trial name
- NCT00269958
- Testing
- epoetin alfa
- Volunteers
- 208 people
- Sponsor
- Janssen-Ortho Inc., Canada
Osteoarthritis of the Hip or Knee
Dexibuprofen 400 mg Sachet Versus Ibuprofen 400 mg Sachet in Patients With Osteoarthritis of the Hip or Knee
Medical condition under investigation: Osteoarthritis of the hip or knee Number of patients planned: 480 adult patients Main objective: To evaluate and compare the tolerability profile of Dexibuprofen Gebro 400 mg powder for oral…
- Trial name
- NCT01066676
- Testing
- Dexibuprofen, Ibuprofen
- Where
- 2 sites in Austria
- Volunteers
- 482 people
- Sponsor
- Gebro Pharma GmbH
Hip Osteoarthritis, Knee Osteoarthritis
Prevalence,Natural History,Prognosis Factor,QualityofLife,Health Care Consumption and Social Consequences of Symptomatic Knee and Hip Osteoarthritis in France
The aim of the project is to assemble and to follow on a 10-year period a nationwide representative sample of lower limb OA patients.
- Trial name
- KHOALA (NCT00481338)
- Testing
- X-rays, biological samples, medical information about osteoarthritis
- Where
- 6 sites in France
- Volunteers
- 878 people
- Sponsor
- Central Hospital, Nancy, France
Heterotopic Ossification
Influence of Naproxen on Heterotropic Bone Formation Following Hip Arthroscopy
In a brief summary the study would like to evaluate the effectiveness of Naproxen in preventing radiographically detected heterotopic ossification following hip arthroscopy for the treatment of femoroacetabular impingement.
- Trial name
- NCT01539447
- Testing
- Naproxen
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Utah
Osteoarthritis, Osteoarthritis, Hip
A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related Pain
The purpose of this study is to compare the safety and effectiveness of different doses of JNJ-42160443 with placebo in the treatment of chronic, moderate to severe knee or hip pain in patients with a diagnosis of osteoarthritis.
- Conditions
- Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Pain
- Trial name
- NCT00973141
- Testing
- JNJ-42160443
- Where
- 77 sites in United States, Canada and 2 more
- Volunteers
- 467 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Osteoarthritis
Analysis of Crosslinked and Conventional Polyethylene Explants
This retrospective study will investigate the changes that occur in ultrahigh molecular weight polyethylene (UHMWPE) implants that have been retrieved from joint replacement patients.
- Trial name
- NCT01484002
- Testing
- Total hip arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Anderson Orthopaedic Research Institute
Hip Osteoarthritis, Knee Osteoarthritis
Hip and Knee Scores
Patient-reported outcome measures (PROMs) are currently used for evaluating orthopaedic procedures. Nevertheless, there is no consensus in the different studies, making them difficult to compare .
- Trial name
- HIP-KNEE (NCT04057651)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Lille
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Femoroacetabular Impingement
Longitudinal Evaluation of Hip Cartilage Degeneration: FAI
Femoroacetabular impingement (FAI) is one of the most common mechanisms leading to the development of early cartilage and labral damage in the non-dysplastic hip.
- Trial name
- NCT02408276
- Testing
- dGEMERIC MRI technique
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Hospital for Special Surgery, New York
Osteoarthritis, Hip
Examining the Effect of Neuromuscular Exercises on Movement Control in Hip & Knee Osteoarthritis: A Randomised Proof of Concept and Feasibility Study
This completed study evaluated the effects of a six-week neuromuscular exercise programme on movement control in individuals with hip and/or knee osteoarthritis (OA).
- Conditions
- Osteoarthritis, Hip, Knee OA, Motor Control
- Trial name
- NCT06963892
- Testing
- Neuromuscular Exercise Programme (GLA:D®-based, Usual Physiotherapy Care (NHS Standard)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- University of Southampton
Peripheral Neuropathies, Osteoarthritis
A Proof of Concept Study to Investigate the Effect of a New Treatment in Patient With Chronic Pain
The purpose of this clinical trial conducted in patients suffering from chronic pain is to study the relationship between individual patients' profile and their analgesic response
- Trial name
- NCT02459197
- Testing
- Heat Pain Stimuli A, Heat Pain Stimuli B, Positive Video
- Where
- 6 sites in Belgium, France
- Volunteers
- 114 people
- Sponsor
- Tools4Patient
Osteoarthritis, Knee, Osteoarthritis, Hip
Phase II Study of CG100649 for Primary Osteoarthritis in Male Subjects
The primary objective of this study is to evaluate the safety and efficacy of 3 loading and maintenance dose levels of CG100649 administered for 21 days in the treatment of osteoarthritis pain.
- Trial name
- NCT00530452
- Testing
- CG100649, Silicified microcrystalline cellulose + talc
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- CrystalGenomics, Inc.
Rheumatoid Arthritis, Osteoarthritis
A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the Summit™ hip in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208390
- Testing
- Summit Tapered Hip System
- Where
- 5 sites in China, Hong Kong and 3 more
- Volunteers
- 275 people
- Sponsor
- DePuy International
Fracture, Lengthening; Leg
Pediatric Orthopaedic Implant Safety & Efficacy
Implant devices are important tools - their use is essential across a number of orthopaedic indications, including hip conditions, trauma and limb deformity.
- Conditions
- Fracture, Lengthening; Leg, Orthopedic Disorder, Deformity of Limb
- Trial name
- Global POISE (NCT05361980)
- Testing
- Pediatric orthopaedic implant
- Where
- Canada
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Osteoarthritis of Hip
Bone Mineral Changes Around Stemless and Stemmed Cementless Femoral Components
The purpose of this study is to determine if there is a difference in stress shielding and bone resorption of the proximal femur in two anatomical stem total hip designs.
- Trial name
- NCT00957970
- Testing
- Stemless femoral component, IPS, Depuy cementless femoral stem
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Ewha Womans University
Hip Osteoarthritis, Hip Arthropathy
Dexamethasone for ESPB in Total Hip Arthroplasty
Effect of adding Dexamethasone to Erector Spinae Plane Block in Patients undergoing Total Hip Arthroplasty
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Arthritis
- Trial name
- NCT06789042
- Testing
- 0.9%NaCl, Dexamethasone 4mg
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
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