Clinical trials: Disorder of Upper Respiratory System
Infection Viral
Xanthohumol and Viral Infections (XL)
The aim of the present study is to determine if a regular oral supplementation of xanthohumol attenuate the severity of symptoms and duration of´viral infections.
- Trial name
- NCT06286657
- Testing
- Xanthohumol
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Upper Respiratory Tract Infections, Acute Respiratory Tract Infection
Implementation of Academic Detailing Interventions on Prescribing of Antimicrobial Drugs in Primary Health Care
World increase in mortality from consequences of antimicrobial resistance (AMR) represents a significant public health problem. Irrational prescribing of antimicrobial drugs (AMD) in general population is one of the main causes…
- Conditions
- Upper Respiratory Tract Infections, Acute Respiratory Tract Infection, Viral Infection
- Trial name
- NCT05090475
- Testing
- Academic detailing intervention
- Where
- Croatia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- General Hospital Koprivnica
Upper Respiratory Infection
Efficacy of Cold-FX (CVT-E002) in the Prevention of Upper Respiratory Tract Infections in Healthy Adults
The purpose of the Study is to determine the prophylactic effects of CVT-E002 treatment for upper respiratory tract infections in healthy adult employees working with residents in continuing care facilities.
- Trial name
- NCT00259831
- Testing
- CVT-E002 (Cold-FX); a natural health product
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- CV Technologies
Fever
Comparison of the Efficacy of Intravenous Paracetamol and Ibuprofen in the Treatment of Fever Due to Upper Respiratory Tract Infection
Currently, paracetamol, ibuprofen and nonsteroidal antiinflammatory drugs are widely used by emergency physicians in Turkey for the treatment of fever .
- Trial name
- NCT03918135
- Testing
- Paracetamol, Ibuprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Pamukkale University
Volleyball Players
Diaphragmatic Facilitation and Upper Extremity Performance in Volleyball Players
The diaphragm contributes to both respiration and trunk stabilization. Effective diaphragmatic function may support postural control, force transfer, and upper extremity performance during dynamic activities.
- Trial name
- NCT07784517
- Testing
- Diaphragmatic Facilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istinye University
Post-Thyroidectomy Dysphonia
Effects of Therapeutic Exercise With and Without Nerve Stimulation on Dysphonia in Post Thyroidectomy Patients
This clinical trial evaluates rehabilitation strategies for post-thyroidectomy dysphonia. Voice impairment is a frequent complication following thyroid surgery. It often occurs even without direct laryngeal nerve transection.
- Trial name
- NCT07811154
- Testing
- therapeutic exercise, therapeutic exercise + transcutaneous nerve stimulation
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Chronic Graft Versus Host Disease
A Study to Investigate Safety of Belumosudil in Participants Aged 12 Years and Above, With Chronic Graft-versus-host Disease (cGVHD)
This is an interventional phase IV clinical study which is single-arm study for assessing the safety of belumosudil in Indian patients who are12 years and older.
- Trial name
- NCT07135973
- Testing
- Belumosudil
- Volunteers
- 26 people
- Sponsor
- Sanofi
Carcinomatous Disease
Establishment of an Artificial Larynx After Total Laryngectomy
This study aims to evaluate the effectiveness of an artificial larynx on the restoration of laryngeal functions, mainly breathing and swallowing.
- Trial name
- LA (NCT01474005)
- Testing
- PROTIP MEDICAL ( Artificial larynx prosthesis)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Strasbourg, France
Obstructive Sleep Apnea
Domiciliary Transcutaneous Electrical Stimulation in Obstructive Sleep Apnoea
The aim of this study is to assess the efficacy of transcutaneous electrical stimulation of the pharyngeal dilator muscles in patients with obstructive sleep apnoea in the community compared to usual care, and follow the patients…
- Trial name
- TESLA-home (NCT03160456)
- Testing
- Transcutaneous electrical stimulation, Continuous positive airway pressure
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Sleep Apnea, Obstructive, Child
Effect of CPAP and Adenotonsillectomy in Upper Airway Volume of Children With OSAS
Obstructive sleep apnea syndrome (OSAS) in children has high prevalence and severe complications, and its first line of treatment (adenotonsillectomy) has risk of complications.
- Conditions
- Sleep Apnea, Obstructive, Child, Continuous Positive Airway Pressure, Adenoidectomy
- Trial name
- NCT03169491
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Enfermedades Respiratorias
Airway Stenosis, Upper Airway Obstruction
Flow-Controlled Versus Volume-Controlled Ventilation During Balloon Dilatation Under Direct Laryngoscopy
This prospective trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on airway pressures and oxygenation in adult patients undergoing balloon dilatation under direct…
- Trial name
- NCT07430124
- Testing
- FCV Group, VCV Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara Etlik City Hospital
Sleep Apnea
Influence of Didgeridoo Practice on UA Obstruction Levels in Moderate OSA
Didgeridoo practice has been shown to improve OSA severity. The aim of our study is to assess the changes in upper airways obstruction levels before and after Didgeridoo practice in moderate OSA patients.
- Trial name
- NCT02159664
- Testing
- didgeridoo practice
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Sore Throat Due to a Common Cold
Efficacy and Safety of a Sore Throat Lozenge Containing Lidocaine and Cetylpyridinium Chloride in Patients With Sore Throat Due to a Common Cold.
This study will compare the efficacy and safety of a single dose of a lidocaine 8 mg + cetylpyridimium chloride (CPC) 2 mg lozenge with a single dose of a lidocaine 1 mg + CPC 2 mg lozenge in the treatment of sore throat due to a…
- Trial name
- NCT01265446
- Testing
- Lidocaine 8mg + CPC 2mg, Lidocaine 1mg + CPC 2mg
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Novartis
Covid19
Safety and Immunogenicity of SARS-CoV-2 Protein Subunit Recombinant Vaccine
The study is an observer-blind, randomized, controlled prospective intervention study of Phase I. The primary objective is To evaluate the safety of the SARS-CoV-2 protein subunit recombinant vaccine within 7 days after each dose.
- Trial name
- NCT05067894
- Testing
- SARS-CoV-2 Protein Subunit Recombinant Vaccine, SARS-CoV-2 Inactivated Vaccine
- Where
- Indonesia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- PT Bio Farma
Health Services Misuse, Physician's Practice Patterns
Primary Care Clinician Commitments to Choosing Wisely®
This pragmatic trial examines the uptake and effects of primary care clinician commitments to follow 3 Choosing Wisely® recommendations.
- Conditions
- Health Services Misuse, Physician's Practice Patterns, Guideline Adherence, Unnecessary Procedures
- Trial name
- NCT02247050
- Testing
- Commitment invitation
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- University of Michigan
Antibiotic Associated Diarrhea, Upper Respiratory Tract Infection
Effectiveness of Saccharomyces Boulardii in Prevention of Antibiotic Associated Diarrhea
Antibiotic-associated diarrhea (AAD) is a common adverse effect in pediatric patients receiving broad-spectrum antibiotics such as co-amoxiclav for upper respiratory tract infections (URTI).
- Trial name
- NCT07785206
- Testing
- Co-amoxiclav, Saccharomyces boulardii
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
COVID-19
Sequential Immunization of Two Doses of Inactivated COVID-19 Vaccine (Omicron) in Vaccinated Population Aged 18 Years and Above
This trial adopts a randomized, double-blind and positive control design, it is planned to recruit 1800 healthy participants who have been vaccinated with 2/3 doses of COVID-19 inactivated vaccine or mRNA vaccine for 3 months.
- Trial name
- COVID-19 (NCT05382871)
- Testing
- BIBP Omicron Inactivated COVID-19 vaccine (Vero Cell), WIBP Omicron Inactivated COVID-19 vaccine (Vero Cell), COVID-19 Vaccine (Vero Cell), Inactivated
- Where
- Hong Kong
- Volunteers
- 1,804 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Respiratory Tract Infections
Prevention of Respiratory Infections Among Children Under 3 Years of Age Attending Daycare Centres
The aim of this study is to evaluate the influence of Primary and Secondary Prevention of Respiratory Infections in children up to 3 years-old attending daycare.
- Trial name
- PRICAD (NCT02588963)
- Testing
- Health education session, Nasal clearance Protocol, Control
- Where
- Portugal
- Volunteers
- 200 people
- Sponsor
- Polytechnic Institute of Porto
Emphysema, Chronic Obstructive Pulmonary Disease (COPD)
Study of the AeriSeal System Treatment in Patients With Advanced Non-Upper Lobe Predominant Heterogeneous Emphysema
The purpose of this study is to prospectively evaluate the safety and efficacy of the AeriSeal System in patients with advanced Non-Upper Lobe Predominant Heterogeneous Emphysema.
- Trial name
- NCT01908933
- Testing
- AeriSeal Emphysematous Lung Sealant Syst
- Sponsor
- Aeris Therapeutics
Acute Respiratory Infection, Viral Infection
Rapid Diagnosis of Viral Acute Respiratory Infection to Decrease Unnecessary Antibiotic Utilization in the Emergency Department (RADIATE)
The study titled " The Effect of Definitive Identification of Viral Etiology in Emergency Department Patients with Acute Respiratory Infection on Antibiotic Utilization (RADIATE)" aims to investigate the effectiveness of a rapid…
- Conditions
- Acute Respiratory Infection, Viral Infection, Upper Respiratory Tract Infections
- Trial name
- RADIATE (NCT06271655)
- Testing
- SPOTFIRE R Panel
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Christopher Payette