Clinical trials: Disorder of Vein
Iron Deficiency Anemia of Pregnancy
Iron Infusion Into a Vein Compared to Iron Tablet Taken by Mouth for Treating Iron Deficiency Anemia in Pregnancy (IVON)
Background: Anaemia in pregnancy is a public health burden with high incidence in Africa. Currently high dose oral iron is recommended for treatment of mild to moderate anaemia and blood transfusion for severe anaemia.
- Trial name
- IVON (NCT04976179)
- Testing
- Ferric carboxymaltose, Ferrous sulfate
- Where
- 11 sites in Nigeria
- Volunteers
- 1,056 people, healthy volunteers welcome
- Sponsor
- University of Lagos, Nigeria
Venous Thromboembolism
Dose-ranging Study of Once-daily Regimen of BAY 59-7939 in the Prevention of VTE in Patients Undergoing Elective Total Hip Replacement
The purpose of this study is to assess different doses of a new drug (BAY 59-7939), taken as a tablet, are safe and can help prevent blood clots forming after a hip replacement operation.
- Trial name
- ODIXaHIP-OD (NCT00396786)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Enoxaparin
- Where
- 62 sites in Austria, Belgium and 11 more
- Volunteers
- 877 people
- Sponsor
- Bayer
Gastric Cancer, Venous Thromboembolism
Incidence of Venous Thromboembolism Following Surgery in Patients With Gastric Cancer
Venous thromboembolism (VTE) has considerably harmful effects on morbidity and mortality of cancer patients. Several guidelines recommendations have been made about the use of anticoagulation for the prevention and treatment of…
- Conditions
- Gastric Cancer, Venous Thromboembolism, Postoperative Period
- Trial name
- NCT01345773
- Testing
- Gastric surgery
- Where
- South Korea
- Volunteers
- 375 people
- Sponsor
- Seoul National University Bundang Hospital
Postpartum Hemorrhage (PPH), Postpartum Hemorrhage Third Stage of Labour Retained Placenta
Intra-Umbilical Vein Oxytocin Injection as an Adjunct to Active Management of the Third Stage of Labour
This randomized controlled clinical trial evaluates the effect of umbilical vein injection of oxytocin given in addition to routine active management of the third stage of labour.
- Trial name
- NCT07436286
- Testing
- Oxytocin
- Where
- Nigeria
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Dangana Zakari Adeka
Pneumothorax Iatrogenic Postprocedural, Malposition, Central Venous Catheter
Comparison of Bedside Ultrasound With Chest X-ray for Confirmation of Central Venous Catheter Position
Background: Insertion of a central venous catheter (CVC) could lead to a variety of complications. To detect those complications, Chest X-ray (CXR) is still the reference standard.
- Trial name
- COMBUX (NCT02959203)
- Where
- Netherlands
- Volunteers
- 750 people
- Sponsor
- Amsterdam UMC, location VUmc
Venous Leg Ulcer
Safety Study to Examine the Systemic Exposure of Granexin® Gel After Topical Application to Venous Leg Ulcers
The purpose of this study is to determine the systemic exposure of Granexin® gel after topical application to human subjects' venous leg ulcers.
- Trial name
- NCT02652572
- Testing
- Granexin
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Xequel Bio, Inc.
Circulatory Function, Laparoscopic Radical Cystectomy for Bladder Cancer
Circulatory Function in Laparoscopic Radical Cystectomy for Bladder Cancer
To optimize the perioperative management of patients undergoing laparoscopic radical cystectomy(LPC) for bladder cancer through observation of perioperative changes of Brain Natriuretic Peptide(BNP), stroke volume variation(SVV)…
- Trial name
- NCT03892031
- Where
- China
- Volunteers
- 186 people
- Sponsor
- RenJi Hospital
Menopause, Thrombophilia
Effect of DT56a (Femarelle) on the Coagulation System in the Treatment of Postmenopausal Women
The purpose of this study is to determine if Femeralle (DT56a) has an effect on the coagulation system, measured by platelet adhesion and aggregation, of normal and thrombophilic postmenopausal women.
- Trial name
- NCT00883272
- Testing
- DT56a (Femarelle) [Se-cure pharmaceuticals, Dalton, Israel]
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Major Orthopaedic Surgery and Renal Impairment
Prospective, Multicentre, Open-label Study Evaluating 1.5 mg/Day of Fondaparinux.
Fondaparinux is an antithrombotic agent having already received a regulatory approval by the European Authorities in venous thromboembolic event prevention after major orthopaedic surgery, as total hip replacement (THR), total…
- Trial name
- PROPICE (NCT00555438)
- Testing
- fondaparinux 1.5 mg/day
- Where
- 29 sites in France
- Volunteers
- 451 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Varicose Veins, Veins Diseases
Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFU
This is a one-arm, open label, prospective, single center study to evaluate clinical standardization with Theraclion's Sonovein 2 HIFU device.
- Conditions
- Varicose Veins, Veins Diseases, Varicose Ulcer
- Trial name
- NCT04280679
- Testing
- Sonovein 2
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Theraclion
Hemorrhage, Cerebrovascular Accident
Antiplatelet Therapy Continuation in Spine Surgery - Its Effect on Postoperative Morbidity and Mortality
The objective of this study is to evaluate the safety of antiplatelet (APA)therapy continuation in patients undergoing lumbar spine surgery (laminectomy, discectomy and foraminotomy), and to gather evidence-based data regarding…
- Conditions
- Hemorrhage, Cerebrovascular Accident, Myocardial Infarction, Pulmonary Embolism
- Trial name
- NCT01006083
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Portal Hypertension, Budd-Chiari Syndrome
Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in India
There is a need to re-evaluate the patients classified as NCPH and determine whether the new histological classification proposed by the VALDIG applies to the Indian scenario.
- Conditions
- Portal Hypertension, Budd-Chiari Syndrome, Non-Cirrhotic Portal Hypertension, Porto-Sinusoidal Vascular Diseases
- Trial name
- PSVD-India (NCT06054451)
- Where
- India
- Volunteers
- 210 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Venous Leg Ulcer
DermaRep™ Device in the Treatment of Venous Leg Ulcers
This is a First in Human clinical study on the safety and effectiveness of DermaRep™ wound contact dressing. Patients with venous leg ulcers will be treated with standard of care dressings and compression for 4 weeks to establish…
- Trial name
- DermaRep™ (NCT03699072)
- Testing
- DermaRep™ Wound Contact Device
- Where
- 6 sites in United Kingdom
- Volunteers
- 39 people
- Sponsor
- Biovotec AS
Thrombosis, Venous
The Impact of MTM Model on the Efficacy and Safety of Anticoagulant Therapy in Postoperative Colorectal Cancer Patients
Anticoagulants are classified as high-risk medications, with their main adverse drug events (ADEs) being recurrent venous thromboembolism (VTE) and bleeding events.Postoperative colorectal cancer (CRC) patients exhibit a high…
- Trial name
- NCT06998745
- Testing
- Medication Therapy Management (MTM) model
- Where
- China
- Volunteers
- 327 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Deep Vein Thrombosis (DVT)
COMPARISON OF WARFARIN AND RIVAROXABAN IN THE TREATMENT OF LOWER LIMB DEEP VENOUS THROMBOSIS
This was a randomized controlled trial conducted at General Surgical wards of Mayo Hospital, Lahore.Total 74(37 in each group) patients were included.After heparinizing patients for 48 hours (80 units/kg/stat and 18…
- Trial name
- NCT07077954
- Testing
- Rivaroxaban, Warfarin
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Pancreatic Neoplasm Malignant Head Primary
A New Anatomical Classification of Portal Vein Location of Pancreas Tumors
In this retrospective study, we recorded the location of pancreatic tumors and relation/proximity to the portal vein. The surgical difficulty and requirement of additional interventions were also evaluated.
- Trial name
- NCT04416685
- Testing
- primary repair, segmental resection, graft reconstruction
- Volunteers
- 43 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Acute Deep Venous Thrombosis
Endovascular Therapy in Patients With Acute Deep Vein Thrombosis
Despite optimal anticoagulation therapy of patients with proximal deep vein thrombosis (DVT), there is still high number of patients suffering from post-thrombotic syndrome (PTS) due to the chronic venous occlusion, suboptimal…
- Trial name
- LEVANTE (NCT05827120)
- Testing
- Mechanical / pharmacomechanical thrombectomy plus local catheter directed thrombolysis, Local catheter directed thrombolysis alone
- Where
- 3 sites in Slovakia
- Volunteers
- 110 people
- Sponsor
- National Institute of Cardiovascular Diseases, Slovakia
Critical Illness
An Infraclavicular Landmark-based Approach to the Axillary Vein
The central line placement is the widespread procedure performed in the intensive care and emergency medicine. Indications for this procedure are chiefly lack of peripheral catheters, administration some medications, renal…
- Trial name
- NCT02083458
- Testing
- Catheterization of the axillary vein.
- Where
- Poland
- Volunteers
- 153 people
- Sponsor
- Uniwersytecki Szpital Kliniczny w Opolu
Venous Leg Ulcer
Suprasorb®X+PHMB Pro vs Suprasorb®X+PHMB in Treatment of Infected Venous Leg Ulcers
This clinical investigation will be conducted as a multicentre, open-label, randomised in parallel groups, controlled study on patients with infected venous leg ulcers.
- Trial name
- NCT07211243
- Testing
- PHMB-impregnated biocellulose wound dressing with additional polyethylene film on top, compression therapy, systemic antomicrobial therapy (optional), PHMB-impregnated biocellulose wound dressing without additional polyethylene film on top, compression therapy, systemic antomicrobial therapy (optional)
- Where
- 9 sites in Poland
- Volunteers
- 150 people
- Sponsor
- Lohmann & Rauscher
Acute Pain, Anxiety
MOLI Technique and Virtual Reality Versus Conventional Venipuncture for Pain and Anxiety in Children
Venipuncture is one of the most frequent and distressing invasive procedures in paediatric care. Both immersive virtual reality (VR) and structured breathing-based active distraction have been proposed as effective…
- Conditions
- Acute Pain, Anxiety, Pain, Procedural, Phlebotomy
- Trial name
- MOLIVeR (NCT07878117)
- Testing
- Conventional venipuncture technique, MOLI technique, Meta Quest 3 with Fruit Ninja VR
- Where
- Spain
- Volunteers
- 201 people
- Sponsor
- José Luis Cobo Sánchez