Clinical trials: Disorder of Vein
Chronic Venous Disease, Chronic Venous Insufficiency, CVI
The ReCAna for Lower ExtremIty Venous OBstructions and In-StEnt Restenosis Registry
The goal of this observational study is to gather additional safety and performance (effectiveness) data on the device for the treatment of symptomatic lower extremity venous obstructions and occlusions.
- Conditions
- Chronic Venous Disease, Chronic Venous Insufficiency, CVI, Venous Thrombosis, Thrombosis (Stent Thrombosis)
- Trial name
- CALIBER (NCT07529756)
- Testing
- Recanalization and debulking
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Intervene, Inc.
Atrial Fibrillation
Use of a Novel Contact Force Sensing Catheter for AF Ablation - Impact of TactiCath on Dormant Conduction Across the Pulmonary Veins
The purpose of this study is to collect information about the success rate of atrial fibrillation (AF) ablation procedures using the contact force data from the TactiCath Quartz ablation catheter.
- Trial name
- FORMIDIBLE (NCT02666729)
- Testing
- AF Ablation with contact force information, AF Ablation without contact force information
- Where
- United States
- Sponsor
- Dhanunjaya Lakkireddy, MD, FACC
Primary Aldosteronism
68Ga-Pentixafor PET/CT for the Subtyping Diagnosis of Primary Aldosteronism
To evaluate the value of 68Ga-Pentixafor PET/CT in the diagnosis of primary aldosteronism subtype
- Trial name
- NCT05131061
- Testing
- 68Ga-Pentixafor PET/CT imaging
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qifu Li
Alcoholic Cirrhosis
Hemodynamic Effects of Chronic Administration of Spironolactone and/or Propranolol in Alcoholic Cirrhotic Patients
The aim of this study was assesment of splanchnic and systemic hemodynamic effects of chronic administration (2 month) of spironolactone or propranolol, alone or in association in alcoholic cirrhotic patients.
- Trial name
- NCT00188045
- Testing
- Propranolol - Spironolactone
- Volunteers
- 54 people
- Sponsor
- University Hospital, Angers
Subarachnoid Hemorrhage, Aneurysmal
The Role of Deep Cerebral Vein Variation in Patients With Angiographic Negative Subarachnoid Hemorrhage
The incidence of Rosenthal basilar vein (BVR) variants (deep venous drainage variants) was relatively increased in patients with AN-SAH compared with patients with aneurysms.
- Trial name
- NCT04941846
- Testing
- nimodipine and euvolemia
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Varicose Veins
Prospective Randomized Trial Comparing the New Endovenous Procedures Versus Conventional Surgery for Varicose Veins Due to Great Saphenous Vein Incompetence
Through a prospective RCT evaluate and compare the three new endovenous methods for great saphenous vein ablation (Radiofrequency, endovenous laser and foam sclerotherapy) versus high ligation and stripping.
- Trial name
- RAFPELS (NCT00621062)
- Testing
- High Ligation of the GSV, Endovenous Laser Ablation, Radiofrequency ablation
- Where
- Sweden
- Volunteers
- 540 people
- Sponsor
- Uppsala University
Wounds and Injuries, Venous Thromboembolism
STAT-STatin and Aspirin in Trauma
This is a phase II, pragmatic, prospective, randomized, double-blind, adaptive clinical trial examining the efficacy of statins and aspirin in the reduction of acute lung injury and venous thromboembolism in patients with…
- Trial name
- STAT (NCT02901067)
- Testing
- Aspirin and Rosuvastatin
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Denver Health and Hospital Authority
Atrial Fibrillation, Heart Failure
Ablation Strategies for Persistent Atrial Fibrillation Combined With Heart Failure
(1) To evaluate the efficacy and safety of "2C3L" strategy combined with VOM anhydrous ethanol chemical ablation for persistent atrial fibrillation complicated with heart failure; (2) To evaluate the effectiveness of…
- Trial name
- NCT06438692
- Testing
- VOM ethanol chemical ablation and 2C3L, 2C3L
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Qianfoshan Hospital
Intrauterine Growth Restriction
FETAL PULMONARY VEIN AND UMBILICAL ARTERY PULSATILITY INDICES AS PREDICTORS OF FETAL GROWTH RESTRICTION IN DIABETIC AND HYPERTENSIVE PREGNANT WOMEN
Diabetic and hypertensive pregnant women attending at Kasr Alani for antenatal care were subjected to Complete History taking. All the participants were scanned using B mode sonography to determine the fetal biometric parameters…
- Trial name
- NCT06988436
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Cairo University
Chronic Venous Insufficiency
Study of Antiinflammatory Effects of Detralex (Daflon)
Aim of the study: To investigate if there is a differences in expression of inflammatory markers in venous wall and blood among patients treated with Detralex and those not treated with Detralex (control group).
- Trial name
- NCT01654016
- Testing
- Detralex
- Where
- Croatia
- Volunteers
- 84 people
- Sponsor
- University Hospital Dubrava
Atrial Fibrillation, Deep Vein Thrombosis
A Pharmacogenetic Study of Warfarin Dosing, "The COUMA-GEN Study"
Anticoagulation with warfarin is a common and potentially hazardous therapeutic intervention. It is a leading cause of iatrogenic bleeding events and, hence, of malpractice claims.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT00334464
- Testing
- Standard of care or genotyping dosing of warfarin dosing
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Intermountain Health Care, Inc.
Deep Vein Thrombosis
MDA D-Dimer / Recurrent DVT Study
To determine whether treatment and further investigation can be safely withheld in patients who present with suspected recurrent deep vein thrombosis (DVT) and have either a (i) negative D-Dimer or (ii) a positive D-Dimer with…
- Trial name
- NCT00157599
- Testing
- various diagnostic measures for DVT (e.g., CUS)
- Where
- 6 sites in Canada, Netherlands
- Volunteers
- 500 people
- Sponsor
- McMaster University
Fractures, Bone, CKD Stage 4
The Effect of Prophylactic Anticoagulation on Major Bleeding Events in Hospitalized Chronic Kidney Disease and Lower Limb Fracture Patients.
the risk of bleeding may be greater than the benefit of antithrombotic protection when prophylactically anticoagulating a patient with a lower limb fracture and advanced CKD.
- Conditions
- Fractures, Bone, CKD Stage 4, CKD Stage 3, CKD Stage 5
- Trial name
- FAA (NCT06795698)
- Testing
- Enoxaparin
- Where
- Mexico
- Volunteers
- 61 people
- Sponsor
- Hospital Civil de Guadalajara
Glucose-6 Phosphate Dehydrogenase Deficiency
Comparing G6PD Tests Using Capillary Blood Versus Venous Blood
In this study we propose to determine the correlation in glucose-6phosphate dehydrogenase enzyme activity in capillary blood obtained from a finger stick versus a venous blood specimen.
- Trial name
- NCT02069236
- Testing
- G6PD Test
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- PATH
Kidney Diseases
Intermittent Pneumatic Compression Device for Vein Dilation in Kidney Disease Patients to Enable AVF Creation (FACT)
This is a single center pilot study that is seeking to determine whether the use of the Fist Assist® device for 360 hours over 90 days by patients with advanced CKD prior to AVF surgery results in significant increases in…
- Trial name
- FACT (NCT04063787)
- Testing
- Fist Assist
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Chicago
Biliary Tract Cancer, Portal Vein Embolization
Effect of PVE on Surgical Outcomes and Long-term Survival in Perihilar Cholangiocarcinoma
Portal vein embolization is often recommended to reduce the risk of postoperative liver failure and mortality. In this retrospective cohort study, researchers investigated the effect of portal vein embolization in patients with…
- Trial name
- NCT06222619
- Testing
- Potal vein embilization
- Where
- South Korea
- Volunteers
- 136 people
- Sponsor
- Seoul National University Hospital
Postthrombotic Syndrome
DVT Burden and the Risk of Post-thrombotic Syndrome
Post-thrombotic syndrome (PTS) is the most common chronic complication of deep vein thrombosis (DVT), with major consequences for patient quality of life and cost of management.
- Trial name
- DVT-Burden (NCT06385353)
- Testing
- Quantification of deep vein thrombosis burden and assessment of post-thrombotic syndrome
- Where
- 27 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Non-Small Cell Lung Carcinoma, Venous Thromboembolism
Hypercoagulable Parameters as Predictors of Thrombotic Events and Prognosis in Patients With Advanced Non-Small Cell Lung Carcinoma
The association between cancer and thrombosis is well known and the occurrence of thrombotic complications is commonly associated with poor prognosis.
- Trial name
- NCT00192829
- Testing
- Blood sample withdrawal
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Venous Thromboembolism
Replication of the AMPLIFY Anticoagulant Trial in Healthcare Claims Data
Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials.
- Trial name
- NCT04736719
- Testing
- Apixaban, Warfarin
- Where
- United States
- Volunteers
- 19,002 people
- Sponsor
- Brigham and Women's Hospital
Pancreatic Cancer, Venous Thromboembolism
Dalteparin for Primary Venous Thromboembolism (VTE) Prophylaxis in Pancreatic Cancer Patients
The goal of this clinical research study is to learn if dalteparin can lower the risk of VTE occurring in the legs and lungs. This will be tested in patients with pancreatic cancer who are going to receive chemotherapy.
- Trial name
- NCT00966277
- Testing
- Dalteparin
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- M.D. Anderson Cancer Center
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